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2024-7-17 7:45:13
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Larbi I, Ghedira K, Marwa A, Butcher GD, Rego N, N. Phylogenetic analysis and assessment of the pathogenic potential of the first H9N2 avian influenza viruses isolated from wild birds and lagoon water in Tunisia. Virus Res. 2022 Sep 17:198929.  Abstract  
submitted by kickingbird at Sep, 21, 2022 from Virus Res. 2022 Sep 17:198929 (via https://www.sciencedirect.com/science/article/abs/pii/S01681)
H9N2 avian influenza virus (AIV) has been isolated from various species of wild birds and domestic poultry worldwide. It has been reported since the late 1990s, that H9N2 AIV has infected humans as reported ...

Ogrzewalska M, Couto Motta F, Resende PC, Fumian T. Influenza A(H11N2) Virus Detection in Fecal Samples from Adélie ( Pygoscelis adeliae) and Chinstrap ( Pygoscelis antarcticus) Penguins, Penguin Island, Antarctica. Microbiol Spectr. 2022 Sep 19:e0142722.  Abstract  
submitted by kickingbird at Sep, 20, 2022 from Microbiol Spectr. 2022 Sep 19:e0142722 (via https://journals.asm.org/doi/10.1128/spectrum.01427-22)
Influenza A viruses infect a range of host species, including a large variety of mammals and more than a hundred species of birds. A total of 95 avian fecal samples were collected from penguin colonies ...

Shartouny JR, Lee CY, Delima GK, Lowen AC. Beneficial effects of cellular coinfection resolve inefficiency in influenza A virus transcription. PLoS Pathog. 2022 Sep 19;18(9):e1010865.  Abstract  
submitted by kickingbird at Sep, 20, 2022 from PLoS Pathog. 2022 Sep 19;18(9):e1010865 (via https://journals.plos.org/plospathogens/article?id=10.1371/j)
For diverse viruses, cellular infection with single vs. multiple virions can yield distinct biological outcomes. We previously found that influenza A/guinea fowl/Hong Kong/WF10/99 (H9N2) virus (GFHK99) ...

Sicca F, Sakorafa E, de Jonge A, de Vries-Idema J,. The evolution of humoral immune responses to past and novel influenza virus strains gives evidence for antigenic seniority. Front Immunol. 2022 Sep 2;13:987984.  Abstract  
submitted by kickingbird at Sep, 19, 2022 from Front Immunol. 2022 Sep 2;13:987984 (via https://www.frontiersin.org/articles/10.3389/fimmu.2022.9879)
The high genetic and antigenic variability of influenza virus and the repeated exposures of individuals to the virus over time account for the human immune responses toward this pathogen to continuously ...

Rengui Yang, et al. Human infection of avian influenza A H3N8 virus and the viral origins: a descriptive study. Lancet Microbe 14 September 2022.  Abstract  
submitted by kickingbird at Sep, 18, 2022 from Lancet Microbe 14 September 2022 (via https://www.sciencedirect.com/science/article/pii/S266652472)
BackgroundThe H3N8 avian influenza virus (AIV) has been circulating in wild birds, with occasional interspecies transmission to mammals. The first human infection of H3N8 subtype occurred in Henan Province, ...

Zhang Q, Pizzorno A, Miorin L, Bastard P, Gervais. Autoantibodies against type I IFNs in patients with critical influenza pneumonia. J Exp Med. 2022 Nov 7;219(11):e20220514.  Abstract  
submitted by kickingbird at Sep, 18, 2022 from J Exp Med. 2022 Nov 7;219(11):e20220514 (via https://rupress.org/jem/article/219/11/e20220514/213469/Auto)
Autoantibodies neutralizing type I interferons (IFNs) can underlie critical COVID-19 pneumonia and yellow fever vaccine disease. We report here on 13 patients harboring autoantibodies neutralizing IFN-α2 ...

Sia ZR, Chiem K, Huang WC, Seffouh A, Teimouri Der. Respiratory Vaccination with Hemagglutinin Nanoliposomes Protects Mice from Homologous and Heterologous Strains of Influenza Virus. J Virol. 2022 Sep 15:e0100622.  Abstract  
submitted by kickingbird at Sep, 18, 2022 from J Virol. 2022 Sep 15:e0100622 (via https://journals.asm.org/doi/10.1128/jvi.01006-22)
Intranasal vaccination offers the potential advantage of needle-free prevention of respiratory pathogens such as influenza viruses with induction of mucosal immune responses. Optimal design of adjuvants ...

Yesilbag K, Toker EB, Ates O. Recent strains of influenza D virus create a new genetic cluster for European strains. Microb Pathog. 2022 Sep 11:105769.  Abstract  
submitted by kickingbird at Sep, 15, 2022 from Microb Pathog. 2022 Sep 11:105769 (via https://www.sciencedirect.com/science/article/abs/pii/S08824)
Bovine respiratory diseases(BRD) are one of the significant health problems for cattle breeding industry. Influenza D virus(IDV) alone or in combination with other respiratory pathogens plays a role in ...

Alkie TN, Lopes S, Hisanaga T, Xu W, Suderman M, K. A threat from both sides: Multiple introductions of genetically distinct H5 HPAI viruses into Canada via both East Asia-Australasia/Pacific and Atlantic flyways. Virus Evol. 2022 Aug 25;8(2):veac077.  Abstract  
submitted by kickingbird at Sep, 15, 2022 from Virus Evol. 2022 Aug 25;8(2):veac077 (via https://academic.oup.com/ve/article/8/2/veac077/6675431)
From 2016 to 2020, high pathogenicity avian influenza (HPAI) H5 viruses circulated in Asia, Europe, and Africa, causing waves of infections and the deaths of millions of wild and domestic birds and presenting ...

Motahhar M, Keyvanfar H, Shoushtari A, Fallah Mehr. The arrival of highly pathogenic avian influenza viruses H5N8 in Iran through two windows, 2016. Virus Genes. 2022 Sep 13.  Abstract  
submitted by kickingbird at Sep, 15, 2022 from Virus Genes. 2022 Sep 13 (via https://link.springer.com/article/10.1007/s11262-022-01930-8)
The highly pathogenic avian influenza (HPAI) H5N1 virus has received considerable attention during the past 2 decades due to its zoonotic and mutative features. This Virus is of special importance due ...

Caliendo V, Leijten L, van de Bildt MWG, Poen MJ,. Long-Term Protective Effect of Serial Infections with H5N8 Highly Pathogenic Avian Influenza Virus in Wild Ducks. J Virol. 2022 Sep 13:e0123322.  Abstract  
submitted by kickingbird at Sep, 15, 2022 from J Virol. 2022 Sep 13:e0123322 (via https://journals.asm.org/doi/10.1128/jvi.01233-22)
Highly pathogenic avian influenza viruses (HPAIVs) of the Goose/Guangdong (Gs/Gd) lineage are an emerging threat to wild birds. In the 2016-2017 H5N8 outbreak, unexplained variability was observed in susceptible ...

Sun H, Liu H, Liu Y, Pang Z, Jiang Y, Liu Q, Liao. Genetic characterization of a novel quadruple reassortant influenza A (H1N2) virus from swine, China, 2021. J Infect. 2022 Sep 10:S0163-4453(22)00538-2.  Abstract  
submitted by kickingbird at Sep, 15, 2022 from J Infect. 2022 Sep 10:S0163-4453(22)00538-2 (via https://www.journalofinfection.com/article/S0163-4453(22)005)
We read with interest a recent letter in the Journal of Infection, which reported the emergence of novel H5N6 reassortant and it's threat to both birds and humans. Pigs are susceptible to human, swine, ...

Ke X, Yao Z, Tang Y, Yang M, Li Y, Yang G, Chen J,. Highly Pathogenic Avian Influenza A (H5N1) Virus in Swans, Central China, 2021. Microbiol Spectr. 2022 Sep 14:e0231522.  Abstract  
submitted by kickingbird at Sep, 15, 2022 from Microbiol Spectr. 2022 Sep 14:e0231522 (via https://journals.asm.org/doi/10.1128/spectrum.02315-22)
Six highly pathogenic avian influenza (HPAI) H5N1 viruses (clade 2.3.4.4b) were detected in migratory birds in Hubei Province in November 2021. Phylogenetic analysis indicated that the viruses in the study ...

Zhao L, Liu Q, Huang J, Lu Y, Zhao Y, Ping J. TREX (transcription/export)-NP complex exerts a dual effect on regulating polymerase activity and replication of influenza A virus. PLoS Pathog. 2022 Sep 9;18(9):e1010835.  Abstract  
submitted by kickingbird at Sep, 14, 2022 from PLoS Pathog. 2022 Sep 9;18(9):e1010835 (via https://journals.plos.org/plospathogens/article?id=10.1371/j)
Influenza A viruses effectively hijack the intracellular "resources" to complete transcription and replication, which involve extensive interactions between the viral and host proteins. Herein, we screened ...

Qiu J, Tian X, Liu Y, Lu T, Wang H, Shi Z, Lu S, X. Univ-flu: A structure-based model of influenza A virus hemagglutinin for universal antigenic prediction. Comput Struct Biotechnol J. 2022 Aug 28;20:4656-46.  Abstract  
submitted by kickingbird at Sep, 14, 2022 from Comput Struct Biotechnol J. 2022 Aug 28;20:4656-46 (via https://www.sciencedirect.com/science/article/pii/S200103702)
The rapid mutations on hemagglutinin (HA) of influenza A virus (IAV) can lead to significant antigenic variance and consequent immune mismatch of vaccine strains. Thus, rapid antigenicity evaluation is ...

Tao P, Ning Z, Zhou P, Xiao W, Wang G, Li S, Zhang. H3N2 canine influenza virus NS1 protein inhibits canine NLRP3 inflammasome activation. Vet Immunol Immunopathol. 2022 Sep 6;252:110483.  Abstract  
submitted by kickingbird at Sep, 12, 2022 from Vet Immunol Immunopathol. 2022 Sep 6;252:110483 (via https://www.sciencedirect.com/science/article/abs/pii/S01652)
Inflammation is an innate immune response of the body against pathogens and other irritants. The NLRP3 (NACHT, LRR and PYD domains-containing protein 3) inflammasome is a major player in the inflammatory ...

Hong Y, Truong AD, Vu TH, Lee S, Heo J, Kang S, Li. Profiling and analysis of exosomal miRNAs derived from highly pathogenic avian influenza virus H5N1-infected White Leghorn chickens. Poult Sci. 2022 Aug 8;101(11):102123.  Abstract  
submitted by kickingbird at Sep, 12, 2022 from Poult Sci. 2022 Aug 8;101(11):102123 (via https://www.sciencedirect.com/science/article/pii/S003257912)
Exosomes are small cell membrane-derived vesicles; they play important roles as mediators of cell-to-cell communication via delivery of their contents, such as proteins and microRNAs (miRNAs). In particular, ...

Hofflich B, Lunardhi A, Sunku N, Tsujimoto J, Cauw. Modeling the Viral Kinetics of Influenza A During Infection in Humans. Annu Int Conf IEEE Eng Med Biol Soc. 2022 Jul;2022.  Abstract  
submitted by kickingbird at Sep, 12, 2022 from Annu Int Conf IEEE Eng Med Biol Soc. 2022 Jul;2022 (via https://ieeexplore.ieee.org/document/9871075)
This study explores the natural control system in the body for responding to exposure to the Influenza A virus. More specifically, it delves into the development of a model to simulate the responses of ...

McBride DS, Nolting JM, Nelson SW, Spurck MM, Blis. Shortening Duration of Swine Exhibitions to Reduce Risk for Zoonotic Transmission of Influenza A Virus. Emerg Infect Dis. 2022 Sep 9;28(10)..  Abstract  
submitted by kickingbird at Sep, 11, 2022 from Emerg Infect Dis. 2022 Sep 9;28(10). (via https://pubmed.ncbi.nlm.nih.gov/36084650/)
Reducing zoonotic influenza A virus (IAV) risk in the United States necessitates mitigation of IAV in exhibition swine. We evaluated the effectiveness of shortening swine exhibitions to <72 hours to reduce ...

Dong W, Zhang P, Xu QL, Ren ZD, Wang J. A Study on a Neural Network Risk Simulation Model Construction for Avian Influenza A (H7N9) Outbreaks in Humans in China during 2013-2017. Int J Environ Res Public Health. 2022 Aug 31;19(17.  Abstract  
submitted by kickingbird at Sep, 11, 2022 from Int J Environ Res Public Health. 2022 Aug 31;19(17 (via https://www.mdpi.com/1660-4601/19/17/10877)
The main purposes of this study were to explore the spatial distribution characteristics of H7N9 human infections during 2013-2017, and to construct a neural network risk simulation model of H7N9 outbreaks ...

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