Wang Z, Zhao Q, Huang M, Duan Y, Li F, Wang T. Dual Detection of Hemagglutinin Proteins of H5N1 and H1N1 Influenza Viruses Based on FRET Combined With DNase I. Front Microbiol. 2022 Jun 30;13:934475. Abstract
submitted by kickingbird at Jul, 19, 2022 from Front Microbiol. 2022 Jun 30;13:934475 (via https://www.frontiersin.org/articles/10.3389/fmicb.2022.9344)
Influenza A viruses (IAV) are classified based on their surface proteins hemagglutinin (HA) and neuraminidase (NA). Both pandemic H1N1 (pH1N1) and highly pathogenic avian influenza (HPAI) H5N1 viruses ... Ye H, Zhang J, Sang Y, Shan N, Qiu W, Zhong W, Li. Divergent Reassortment and Transmission Dynamics of Highly Pathogenic Avian Influenza A(H5N8) Virus in Birds of China During 2021. Front Microbiol. 2022 Jun 30;13:913551. Abstract
submitted by kickingbird at Jul, 19, 2022 from Front Microbiol. 2022 Jun 30;13:913551 (via https://www.frontiersin.org/articles/10.3389/fmicb.2022.9135)
Highly pathogenic influenza A(H5N8) viruses had caused several outbreaks among wild bird and poultry populations across the globe, and strikingly, caused human infection, posing serious public health concerns. ... Pulit-Penaloza JA, Belser JA, Brock N, Thakur PB,. Pathogenesis and Transmissibility of North American Highly Pathogenic Avian Influenza A(H5N1) Virus in Ferrets. Emerg Infect Dis. 2022 Jul 15;28(9). Abstract
submitted by kickingbird at Jul, 18, 2022 from Emerg Infect Dis. 2022 Jul 15;28(9) (via https://pubmed.ncbi.nlm.nih.gov/35840125/)
Highly pathogenic avian influenza A(H5N1) viruses have spread rapidly throughout North American flyways in recent months, affecting wild birds in over 40 states. We evaluated the pathogenicity and transmissibility ... Liu M, Huang LZX, Smits AA, Büll C, Narimatsu Y, v. Human-type sialic acid receptors contribute to avian influenza A virus binding and entry by hetero-multivalent interactions. Nat Commun. 2022 Jul 13;13(1):4054. Abstract
submitted by kickingbird at Jul, 16, 2022 from Nat Commun. 2022 Jul 13;13(1):4054 (via https://www.nature.com/articles/s41467-022-31840-0)
Establishment of zoonotic viruses, causing pandemics like the Spanish flu and Covid-19, requires adaptation to human receptors. Pandemic influenza A viruses (IAV) that crossed the avian-human species barrier ... Leow BL, Syamsiah Aini S, Faizul Fikri MY, Muhamma. Molecular characterisation of hemagglutinin and neuraminidase genes of the first highly pathogenic Avian Influenza H5N1 2.3.2.1c virus isolated from Sabah, Malaysia. Trop Biomed. 2022 Jun 1;39(2):160-169. Abstract
submitted by kickingbird at Jul, 16, 2022 from Trop Biomed. 2022 Jun 1;39(2):160-169 (via https://msptm.org/files/Vol39No2/tb-39-2-001-Leow-B-L.pdf)
Highly Pathogenic Avian Influenza (HPAI) is a highly contagious disease in poultry. The outbreaks can lead to flock mortality up to 100% in two to three days. In July 2018, high mortality in a commercial ... ones JC, Zagribelnyy B, Pascua PNQ, Bezrukov DS, B. Influenza A virus polymerase acidic protein E23G/K substitutions weaken key baloxavir drug-binding contacts with minimal impact on replication and transmission. PLoS Pathog. 2022 Jul 13;18(7):e1010698. Abstract
submitted by kickingbird at Jul, 14, 2022 from PLoS Pathog. 2022 Jul 13;18(7):e1010698 (via https://journals.plos.org/plospathogens/article?id=10.1371/j)
Baloxavir marboxil (BXM) is approved for treating uncomplicated influenza. The active metabolite baloxavir acid (BXA) inhibits cap-dependent endonuclease activity of the influenza virus polymerase acidic ... Caliendo V, Lewis NS, Pohlmann A, Baillie SR, Bany. Transatlantic spread of highly pathogenic avian influenza H5N1 by wild birds from Europe to North America in 2021. Sci Rep. 2022 Jul 11;12(1):11729. Abstract
submitted by kickingbird at Jul, 14, 2022 from Sci Rep. 2022 Jul 11;12(1):11729 (via https://www.nature.com/articles/s41598-022-13447-z)
Highly pathogenic avian influenza (HPAI) viruses of the A/Goose/Guangdong/1/1996 lineage (GsGd), which threaten the health of poultry, wildlife and humans, are spreading across Asia, Europe, Africa and ... Xu H, Palpant T, Weinberger C, Shaw DE. Characterizing Receptor Flexibility to Predict Mutations That Lead to Human Adaptation of Influenza Hemagglutinin. J Chem Theory Comput. 2022 Jul 11. Abstract
submitted by kickingbird at Jul, 13, 2022 from J Chem Theory Comput. 2022 Jul 11 (via https://pubs.acs.org/doi/10.1021/acs.jctc.1c01044)
A key step in the emergence of human pandemic influenza strains has been a switch in binding preference of the viral glycoprotein hemagglutinin (HA) from avian to human sialic acid (SA) receptors. The ... Song H, Liu X, Gao X, Li J, Shang Y, Gao W, Li Y,. Transcriptome analysis of pre-immune state induced by interferon gamma inhibiting the replication of H9N2 avian influenza viruses in chicken embryo fibroblasts. Infect Genet Evol. 2022 Jul 7:105332. Abstract
submitted by kickingbird at Jul, 13, 2022 from Infect Genet Evol. 2022 Jul 7:105332 (via https://www.sciencedirect.com/science/article/pii/S156713482)
Interferon (IFN), a critical antiviral cytokine produced by pathogens-induced cells, plays an important role in host innate immune system. In this study, to investigate the inhibition effect of IFN on ... Song Y, Zhu W, Wang Y, Deng L, Ma Y, Dong C, Gonza. Layered protein nanoparticles containing influenza B HA stalk induced sustained cross-protection against viruses spanning both viral lineages. Biomaterials. 2022 Jul 4;287:121664. Abstract
submitted by kickingbird at Jul, 13, 2022 from Biomaterials. 2022 Jul 4;287:121664 (via https://www.sciencedirect.com/science/article/abs/pii/S01429)
The influenza epidemics pose a significant threat to public health. Of them, type B influenza coincided with several severe flu outbreaks. The efficacy of the current seasonal flu vaccine is limited due ... Xu W, Wang Y, Li L, Qu X, Liu Q, Li T, Wu S, Liao. Transmembrane domain of IFITM3 is responsible for its interaction with influenza virus HA 2 subunit. Xu W, Wang Y, Li L, Qu X, Liu Q, Li T, Wu S, Liao. Abstract
submitted by kickingbird at Jul, 11, 2022 from Xu W, Wang Y, Li L, Qu X, Liu Q, Li T, Wu S, Liao (via https://www.sciencedirect.com/science/article/pii/S1995820X2)
Interferon-inducible transmembrane protein 3 (IFITM3) inhibits influenza virus infection by blocking viral membrane fusion, but the exact mechanism remains elusive. Here, we investigated the function and ... Baek YG, Lee YN, Park YR, Chung DH, Kwon JH, Si YJ. Evolution, Transmission, and Pathogenicity of High Pathogenicity Avian Influenza Virus A (H5N8) Clade 2.3.4.4, South Korea, 2014-2016. Front Vet Sci. 2022 Jun 21;9:906944. Abstract
submitted by kickingbird at Jul, 9, 2022 from Front Vet Sci. 2022 Jun 21;9:906944 (via https://www.frontiersin.org/articles/10.3389/fvets.2022.9069)
During 2014-2016, clade 2.3.4.4 H5N8 high pathogenicity avian influenza virus (HPAIV) caused the largest known avian influenza epidemic in South Korea. Based on data from earlier H5N8 outbreaks, primitive ... Tanikawa T, Fujii K, Sugie Y, Tsunekuni R, Nakayam. Comparative susceptibility of mallard (Anas platyrhynchos) to infection with high pathogenicity avian influenza virus strains (Gs/Gd lineage) isolated in Japan in 2004-2017. Vet Microbiol. 2022 Jun 28;272:109496. Abstract
submitted by kickingbird at Jul, 9, 2022 from Vet Microbiol. 2022 Jun 28;272:109496 (via https://www.sciencedirect.com/science/article/pii/S037811352)
The Goose/Guangdong-lineage (Gs/Gd) H5 high pathogenicity avian influenza viruses (HPAIVs) spread among poultry and wild birds worldwide; an association has been identified between the migration of wild ... Si L, Shen Q, Li J, Chen L, Shen J, Xiao X, Bai H,. Generation of a live attenuated influenza A vaccine by proteolysis targeting. Nat Biotechnol. 2022 Jul 4. Abstract
submitted by kickingbird at Jul, 7, 2022 from Nat Biotechnol. 2022 Jul 4 (via https://www.nature.com/articles/s41587-022-01381-4)
The usefulness of live attenuated virus vaccines has been limited by suboptimal immunogenicity, safety concerns or cumbersome manufacturing processes and techniques. Here we describe the generation of ... Wang C, Qu R, Zong Y, Qin C, Liu L, Gao X, Sun H,. Enhanced stability of M1 protein mediated by a phospho-resistant mutation promotes the replication of prevailing avian influenza virus in mammals. PLoS Pathog. 2022 Jul 6;18(7):e1010645.. Abstract
submitted by kickingbird at Jul, 7, 2022 from PLoS Pathog. 2022 Jul 6;18(7):e1010645. (via https://journals.plos.org/plospathogens/article?id=10.1371/j)
Avian influenza virus (AIV) can evolve multiple strategies to combat host antiviral defenses and establish efficient infectivity in mammals, including humans. H9N2 AIV and its reassortants (such as H5N6 ... Rattanaburi S, Sawaswong V, Nimsamer P, Mayuramart. Genome characterization and mutation analysis of human influenza A virus in Thailand. Genomics Inform. 2022 Jun;20(2):e21. Abstract
submitted by kickingbird at Jul, 7, 2022 from Genomics Inform. 2022 Jun;20(2):e21 (via https://genominfo.org/journal/view.php?doi=10.5808/gi.21077)
The influenza A viruses have high mutation rates and cause a serious health problem worldwide. Therefore, this study focused on genome characterization of the viruses isolated from Thai patients based ... Wen F, Zhang X, Guo J, Liang Z, Cheng Q, Wang C, Y. Emergence of H3N8 avian influenza viruses possessing tri-basic hemagglutinin cleavage sites in China. J Infect. 2022 Jul 1:S0163-4453(22)00383-8. Abstract
submitted by kickingbird at Jul, 6, 2022 from J Infect. 2022 Jul 1:S0163-4453(22)00383-8 (via https://www.journalofinfection.com/article/S0163-4453(22)003)
Recently, the first human case of acute respiratory distress syndrome caused by the H3N8 subtype avian influenza virus (AIV) (A/Henan/4-10CNIC/2022, Henan4-10) was documented in this journal. The H3N8 ... Niu X, Wang H, Zhao L, Lian P, Bai Y, Li J, Qiao J. All-trans retinoic acid increases the pathogenicity of the H9N2 influenza virus in mice. Virol J. 2022 Jun 28;19(1):113. Abstract
submitted by kickingbird at Jul, 1, 2022 from Virol J. 2022 Jun 28;19(1):113 (via https://virologyj.biomedcentral.com/articles/10.1186/s12985-)
Background: The H9N2 virus can infect not only birds but also humans. The pathogenicity of H9N2 virus infection is determined by an excessive immune response in the lung. All-trans retinoic acid (ATRA), ... Neveau MN, Zeller MA, Kaplan BS, Souza CK, Gauger. Genetic and Antigenic Characterization of an Expanding H3 Influenza A Virus Clade in U.S. Swine Visualized by Nextstrain. mSphere. 2022 Jun 29;7(3):e0099421. Abstract
submitted by kickingbird at Jul, 1, 2022 from mSphere. 2022 Jun 29;7(3):e0099421 (via https://journals.asm.org/doi/10.1128/msphere.00994-21)
Defining factors that influence spatial and temporal patterns of influenza A virus (IAV) is essential to inform vaccine strain selection and strategies to reduce the spread of potentially zoonotic swine-origin ... Huang WJ, Cheng YH, Tan MJ, Liu J, Li XY, Zeng XX,. Epidemiological and virological surveillance of influenza viruses in China during 2020-2021. Infect Dis Poverty. 2022 Jun 29;11(1):74. Abstract
submitted by kickingbird at Jul, 1, 2022 from Infect Dis Poverty. 2022 Jun 29;11(1):74 (via https://idpjournal.biomedcentral.com/articles/10.1186/s40249)
Background: During the coronavirus disease 2019 (COVID-19) pandemic, seasonal influenza activity declined globally and remained below previous seasonal levels, but intensified in China since 2021. Preventive ... 5200 items, 20/Page, Page[37/260][|<<] [|<] [31] [32] [33] [34] [35] [36] [37] [38] [39] [40] [>|] [>>|] |
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