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2024-7-17 7:28:29
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Vreman S, Kik M, Germeraad E, Heutink R, Harders F. Zoonotic Mutation of Highly Pathogenic Avian Influenza H5N1 Virus Identified in the Brain of Multiple Wild Carnivore Species. Pathogens. 2023 Jan 20;12(2):168.  Abstract  
submitted by kickingbird at Feb, 26, 2023 from Pathogens. 2023 Jan 20;12(2):168 (via https://www.mdpi.com/2076-0817/12/2/168)
Wild carnivore species infected with highly pathogenic avian influenza (HPAI) virus subtype H5N1 during the 2021-2022 outbreak in the Netherlands included red fox (Vulpes vulpes), polecat (Mustela putorius), ...

Tarasiuk K, Kycko A, ?wi?toń E, Bocian ?, Wyrostek. Homo- and Heterosubtypic Immunity to Low Pathogenic Avian Influenza Virus Mitigates the Clinical Outcome of Infection with Highly Pathogenic Avian Influenza H5N8 Clade 2.3.4.4.b in Captive Mallards (. Pathogens. 2023 Jan 30;12(2):217..  Abstract  
submitted by kickingbird at Feb, 26, 2023 from Pathogens. 2023 Jan 30;12(2):217. (via https://www.mdpi.com/2076-0817/12/2/217)
In this study, we investigated the clinical response, viral shedding, transmissibility, pathologic lesions, and tropism of HPAIV Gs/Gd H5N8 subtype (clade 2.3.4.4b), following experimental infection of ...

Braun KM, Haddock Iii LA, Crooks CM, Barry GL, Lal. Avian H7N9 influenza viruses are evolutionarily constrained by stochastic processes during replication and transmission in mammals. Virus Evol. 2023 Jan 19;9(1):vead004.  Abstract  
submitted by kickingbird at Feb, 24, 2023 from Virus Evol. 2023 Jan 19;9(1):vead004 (via https://academic.oup.com/ve/article/9/1/vead004/6991850)
H7N9 avian influenza viruses (AIVs) have caused over 1,500 documented human infections since emerging in 2013. Although wild-type H7N9 AIVs can be transmitted by respiratory droplets in ferrets, they have ...

Aznar E, Casas I, González Praetorius A, Ruano Ram. Influenza A(H5N1) detection in two asymptomatic poultry farm workers in Spain, September to October 2022: suspected environmental contamination. Euro Surveill. 2023 Feb;28(8).  Abstract  
submitted by kickingbird at Feb, 24, 2023 from Euro Surveill. 2023 Feb;28(8) (via https://pubmed.ncbi.nlm.nih.gov/36820643/)
In autumn 2022, the Spanish Influenza National Reference Laboratory (NRL) confirmed the detection of influenza A(H5N1) in samples from two asymptomatic workers linked to an outbreak in a poultry farm in ...

Gu M, Jiao J, Liu S, Zhao W, Ge Z, Cai K, Xu L, He. Monoclonal antibody targeting a novel linear epitope on nucleoprotein confers pan-reactivity to influenza A virus. Appl Microbiol Biotechnol. 2023 Feb 23:1–14..  Abstract  
submitted by kickingbird at Feb, 24, 2023 from Appl Microbiol Biotechnol. 2023 Feb 23:1–14. (via https://link.springer.com/article/10.1007/s00253-023-12433-3)
Nucleoprotein (NP) functions crucially in the replicative cycle of influenza A virus (IAV) via forming the ribonucleoprotein complex together with PB2, PB1, and PA proteins. As its high conservation, NP ...

Liu Y, Zeng Q, Hu X, Xu Z, Pan C, Liu Q, Yu J, Wu. Natural variant R246K in hemagglutinin increased zoonotic characteristics and renal inflammation in mice infected with H9N2 influenza virus. Vet Microbiol. 2023 Feb 3;279:109667.  Abstract  
submitted by kickingbird at Feb, 23, 2023 from Vet Microbiol. 2023 Feb 3;279:109667 (via https://www.sciencedirect.com/science/article/pii/S037811352)
Considered a potential pandemic candidate, the widespread among poultry of H9N2 avian influenza viruses across Asia and North Africa pose an increasing threat to poultry and human health. The massive epidemic ...

Yin Y, Liu Y, Fen J, Liu K, Qin T, Chen S, Peng D,. Characterization of an H7N9 Influenza Virus Isolated from Camels in Inner Mongolia, China. Microbiol Spectr. 2023 Feb 21:e0179822.  Abstract  
submitted by kickingbird at Feb, 23, 2023 from Microbiol Spectr. 2023 Feb 21:e0179822 (via https://journals.asm.org/doi/10.1128/spectrum.01798-22)
The H7N9 subtype of influenza virus can infect birds and humans, causing great losses in the poultry industry and threatening public health worldwide. However, H7N9 infection in other mammals has not been ...

Wang T, Zhang J, Wang Y, Li Y, Wang L, Yu Y, Yao Y. Influenza-trained mucosal-resident alveolar macrophages confer long-term antitumor immunity in the lungs. Nat Immunol. 2023 Feb 20.  Abstract  
submitted by kickingbird at Feb, 23, 2023 from Nat Immunol. 2023 Feb 20 (via https://www.nature.com/articles/s41590-023-01428-x)
Respiratory viral infections reprogram pulmonary macrophages with altered anti-infectious functions. However, the potential function of virus-trained macrophages in antitumor immunity in the lung, a preferential ...

Nemoto M, Reedy SE, Yano T, Suzuki K, Fukuda S, Ga. Antigenic comparison of H3N8 equine influenza viruses belonging to Florida sublineage clade 1 between vaccine strains and North American strains isolated in 2021-2022. Arch Virol. 2023 Feb 19;168(3):94.  Abstract  
submitted by kickingbird at Feb, 23, 2023 from Arch Virol. 2023 Feb 19;168(3):94 (via https://pubmed.ncbi.nlm.nih.gov/36806782/)
Equine influenza virus strains of Florida sublineage clade 1 (Fc1) have been circulating in North America. In this study, virus neutralization assays were performed to evaluate antigenic differences between ...

Chien YA, Alford BK, Wasik BR, Weichert WS, Parris. Single Particle Analysis of H3N2 Influenza Entry Differentiates the Impact of the Sialic Acids (Neu5Ac and Neu5Gc) on Virus Binding and Membrane Fusion. J Virol. 2023 Feb 13:e0146322.  Abstract  
submitted by kickingbird at Feb, 17, 2023 from J Virol. 2023 Feb 13:e0146322 (via https://journals.asm.org/doi/10.1128/jvi.01463-22)
Entry of influenza A viruses (IAVs) into host cells is initiated by binding to sialic acids (Sias), their primary host cell receptor, followed by endocytosis and membrane fusion to release the viral genome ...

He D, Gu M, Wang X, Yan Y, Li Y, Wang X, Hu S, Liu. Reintroduction of highly pathogenic avian influenza A H7N9 virus in southwestern China. Virus Genes. 2023 Feb 13:1–5.  Abstract  
submitted by kickingbird at Feb, 17, 2023 from Virus Genes. 2023 Feb 13:1–5 (via https://link.springer.com/article/10.1007/s11262-023-01974-4)
Highly pathogenic (HP) avian influenza A H7N9 virus has emerged in China since 2016. In recent years, it has been most prevalent in northern China. However, several strains of HP H7N9 reappeared in southwestern ...

Wang S, Zhuang Q, Jiang N, Zhang F, Chen Q, Zhao R. Reverse transcription recombinase-aided amplification assay for avian influenza virus. Virus Genes. 2023 Feb 13.  Abstract  
submitted by kickingbird at Feb, 17, 2023 from Virus Genes. 2023 Feb 13 (via https://link.springer.com/article/10.1007/s11262-023-01979-z)
Avian influenza virus (AIV) infection can lead to severe economic losses in the poultry industry and causes a serious risk for humans. A rapid and simple test for suspected viral infection cases is crucial. ...

Günl F, Krischuns T, Schreiber JA, Henschel L, Wah. The ubiquitination landscape of the influenza A virus polymerase. Nat Commun. 2023 Feb 11;14(1):787.  Abstract  
submitted by kickingbird at Feb, 13, 2023 from Nat Commun. 2023 Feb 11;14(1):787 (via https://www.nature.com/articles/s41467-023-36389-0)
During influenza A virus (IAV) infections, viral proteins are targeted by cellular E3 ligases for modification with ubiquitin. Here, we decipher and functionally explore the ubiquitination landscape of ...

Chen C, Jiang D, Yan D, Pi L, Zhang X, Du Y, Liu X. The global region-specific epidemiologic characteristics of influenza: WHO FluNet data from 1996 to 2021. Int J Infect Dis. 2023 Feb 9:S1201-9712(23)00052-8.  Abstract  
submitted by kickingbird at Feb, 13, 2023 from Int J Infect Dis. 2023 Feb 9:S1201-9712(23)00052-8 (via https://www.ijidonline.com/article/S1201-9712(23)00052-8/ful)
Background: This study aimed to investigate region-specific epidemiologic characteristics of influenza and influenza transmission zones (ITZs).Methods: Weekly influenza surveillance data of 156 countries ...

Heinemann AS, Stalp JL, Bonifacio JPP, Silva F, Wi. Silent neonatal influenza A virus infection primes systemic antimicrobial immunity. Front Immunol. 2023 Jan 24;14:1072142.  Abstract  
submitted by kickingbird at Feb, 11, 2023 from Front Immunol. 2023 Jan 24;14:1072142 (via https://www.frontiersin.org/articles/10.3389/fimmu.2023.1072)
Infections with influenza A viruses (IAV) cause seasonal epidemics and global pandemics. The majority of these infections remain asymptomatic, especially among children below five years of age. Importantly, ...

Li K, McCaw JM, Cao P. Enhanced viral infectivity and reduced interferon production are associated with high pathogenicity for influenza viruses. PLoS Comput Biol. 2023 Feb 9;19(2):e1010886.  Abstract  
submitted by kickingbird at Feb, 10, 2023 from PLoS Comput Biol. 2023 Feb 9;19(2):e1010886 (via https://journals.plos.org/ploscompbiol/article?id=10.1371/jo)
Epidemiological and clinical evidence indicates that humans infected with the 1918 pandemic H1N1 influenza virus and highly pathogenic avian H5N1 influenza viruses often displayed severe lung pathology. ...

Sims A, Tornaletti LB, Jasim S, Pirillo C, Devlin. Superinfection exclusion creates spatially distinct influenza virus populations. PLoS Biol. 2023 Feb 9;21(2):e3001941.  Abstract  
submitted by kickingbird at Feb, 10, 2023 from PLoS Biol. 2023 Feb 9;21(2):e3001941 (via https://journals.plos.org/plosbiology/article?id=10.1371/jou)
Interactions between viruses during coinfections can influence viral fitness and population diversity, as seen in the generation of reassortant pandemic influenza A virus (IAV) strains. However, opportunities ...

Kayed AE, Kutkat O, Kandeil A, Moatasim Y, El Tawe. Comparative pathogenic potential of avian influenza H7N3 viruses isolated from wild birds in Egypt and their sensitivity to commercial antiviral drugs. Arch Virol. 2023 Feb 9;168(3):82.  Abstract  
submitted by kickingbird at Feb, 10, 2023 from Arch Virol. 2023 Feb 9;168(3):82 (via https://link.springer.com/article/10.1007/s00705-022-05646-w)
Active surveillance and studying the virological features of avian-origin influenza viruses are essential for early warning and preparedness for the next potential pandemic. During our active surveillance ...

Vangeti S, Falck-Jones S, Yu M, ?sterberg B, Liu S. Human influenza virus infection elicits distinct patterns of monocyte and dendritic cell mobilization in blood and the nasopharynx. Elife. 2023 Feb 8;12:e77345.  Abstract  
submitted by kickingbird at Feb, 10, 2023 from Elife. 2023 Feb 8;12:e77345 (via https://elifesciences.org/articles/77345)
During respiratory viral infections, the precise roles of monocytes and dendritic cells (DCs) in the nasopharynx in limiting infection and influencing disease severity are incompletely described. We studied ...

Wan Z, Zhao Z, Sang J, Jiang W, Chen J, Tang T, Li. Amino Acid Variation at Hemagglutinin Position 193 Impacts the Properties of H9N2 Avian Influenza Virus. J Virol. 2023 Feb 7:e0137922.  Abstract  
submitted by kickingbird at Feb, 8, 2023 from J Virol. 2023 Feb 7:e0137922 (via https://journals.asm.org/doi/10.1128/jvi.01379-22)
Despite active control strategies, including the vaccination program in poultry, H9N2 avian influenza viruses possessing mutations in hemagglutinin (HA) were frequently isolated. In this study, we analyzed ...

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