Ríos Carrasco M, Lin TH, Zhu X, Gabarroca García A. The Q226L mutation can convert a highly pathogenic H5 2.3.4.4e virus to bind human-type receptors. PNAS 2025 Apr 22;122(16):e2419800122. Abstract
submitted by kickingbird at Apr, 17, 2025 from PNAS 2025 Apr 22;122(16):e2419800122 (via https://www.pnas.org/doi/10.1073/pnas.2419800122)
H5Nx viruses continue to wreak havoc in avian and mammalian species worldwide. The virus distinguishes itself by the ability to replicate to high titers and transmit efficiently in a wide variety of hosts ... Jimenez C, Hoepner LA. Exploring Methods to Evaluate HPAI Transmission Risk in Iowa During Peak HPAI Incidence, February 2022~December 2023. Int J Environ Res Public Health. 2025 Mar 10;22(3). Abstract
submitted by kickingbird at Apr, 17, 2025 from Int J Environ Res Public Health. 2025 Mar 10;22(3) (via https://www.mdpi.com/1660-4601/22/3/400)
Highly pathogenic avian influenza (HPAI), H5N1 strain, began to circulate in the United States on 8 February 2022. The state of Iowa lost the most domestic poultry to HPAI from February 2022-December 2023. ... Pittman Ratterree DC, Chitlapilly Dass S, Ndeffo-M. Estimating the risk of zoonotic transmission of swine influenza A variant during agricultural fairs in the United States: a mathematical modeling. Front Vet Sci. 2025 Apr 1;12:1523981. Abstract
submitted by kickingbird at Apr, 17, 2025 from Front Vet Sci. 2025 Apr 1;12:1523981 (via https://www.frontiersin.org/journals/veterinary-science/arti)
Introduction: Agricultural fairs offer a unique interface between humans and swine. We investigate the transmissibility of influenza A variant from pigs to humans using epidemiological data from a 2011 ... Katzner TE, Blackford AV, Donahue M, Gibbs SEJ, Le. Safety and Immunogenicity of Poultry Vaccine for Protecting Critically Endangered Avian Species against Highly Pathogenic Avian Influenza Virus, United States. Emerg Infect Dis. 2025 Jun. Abstract
submitted by kickingbird at Apr, 17, 2025 from Emerg Infect Dis. 2025 Jun (via https://wwwnc.cdc.gov/eid/article/31/6/24-1558_article)
In 2023, an outbreak of highly pathogenic avian influenza occurred among critically endangered California condors (Gymnogyps californianus), and >21 died. We evaluated safety, immunogenicity, vaccination ... Takashita E, Morita H, Nagata S, Fujisaki S, Miura. Influenza A(H1N1)pdm09 Virus with Reduced Susceptibility to Baloxavir, Japan, 2024. Emerg Infect Dis. 2025 May. Abstract
submitted by kickingbird at Apr, 15, 2025 from Emerg Infect Dis. 2025 May (via https://wwwnc.cdc.gov/eid/article/31/5/24-1123_article)
Influenza A(H1N1)pdm09 virus carrying an I38N substitution was detected in an untreated teenager in Japan. The I38N mutant virus exhibited reduced susceptibility to baloxavir but remained susceptible to ... Akhtar Z, Moa AM, Tan TC, Fr?bert O, Menzies R, Ma. Prevention of Cardiovascular Diseases with Standard-Dose Quadrivalent Influenza Vaccine in People Aged ≥50 Years in Australia During the 2017 A/H3N2 Epidemic. Vaccines. 2025; 13(4):407. Abstract
submitted by kickingbird at Apr, 15, 2025 from Vaccines. 2025; 13(4):407 (via https://www.mdpi.com/2076-393X/13/4/407)
Background: In Australia, 2017 was a severe A/H3N2 season and, therefore, we estimated the effectiveness of standard-dose quadrivalent influenza vaccine in preventing hospitalization for cardiovascular ... Uhart, M.M., Vanstreels, R.E.T., Nelson, M.I. et a. Epidemiological data of an influenza A/H5N1 outbreak in elephant seals in Argentina indicates mammal-to-mammal transmission. Nat Commun 15, 9516 (2024). Abstract
submitted by kickingbird at Apr, 14, 2025 from Nat Commun 15, 9516 (2024) (via https://www.nature.com/articles/s41467-024-53766-5)
H5N1 high pathogenicity avian influenza virus has killed thousands of marine mammals in South America since 2022. Here we report epidemiological data and full genome characterization of clade 2.3.4.4b ... Morris SE, Mathis SM, Reeves E, Chung JR, Borcheri. Modeling the Potential Impacts of Outpatient Antiviral Treatment in Reducing Influenza-Associated Hospitalizations in the United States. J Infect Dis. 2025 Apr 12:jiaf061. Abstract
submitted by kickingbird at Apr, 13, 2025 from J Infect Dis. 2025 Apr 12:jiaf061 (via https://academic.oup.com/jid/advance-article-abstract/doi/10)
Background: Seasonal influenza causes an estimated 120 000 to 710 000 hospitalizations annually in the United States. Treatment with antiviral medications, such as oseltamivir, can reduce risks of hospitalization ... Claudio Campagna, Richard Condit, etc.,al. Predicting Population Consequences of an Epidemic of High Pathogenicity Avian Influenza on Southern Elephant Seals. Marine Mammal Science. Abstract
submitted by kickingbird at Apr, 13, 2025 from Marine Mammal Science (via https://onlinelibrary.wiley.com/doi/10.1111/mms.70009)
The colony of southern elephant seals (Mirounga leonina) at Península Valdés (Argentina) grew by 0.9% from 2000 to 2022, reaching a population of 18,000 reproductive females. In 2023, an epidemic of the ... Juan Li, Bingxin Nie, etc.,al. Modelling for assessing the compulsory vaccination strategy against highly pathogenic avian influenza in a poultry farm of China. Applied Mathematical Modelling. Abstract
submitted by kickingbird at Apr, 13, 2025 from Applied Mathematical Modelling (via https://www.sciencedirect.com/science/article/pii/S0307904X2)
The prevalence of highly pathogenic avian influenza (HPAI) has become substantial obstacles for the poultry industry and international trade with potential threat to human health. We developed a data-driven ... Adu OF, Sempere Borau M, Früh SP, Karakus U, Weich. Cell binding, uptake, and infection of influenza A virus using recombinant antibody-based receptors. J Virol. 2025 Apr 10:e0227524. Abstract
submitted by kickingbird at Apr, 13, 2025 from J Virol. 2025 Apr 10:e0227524 (via https://journals.asm.org/doi/10.1128/jvi.02275-24)
Human and avian influenza A viruses bind to sialic acid (Sia) receptors on cells as their primary receptors, and this results in endocytic uptake of the virus. While the role of Sia on glycoproteins and/or ... Zhang X, Zhou Q, Bu S, Yang Y, Wang L, Xu C, Hao Z. A lateral flow biosensor based on duplex-specific nuclease and novel isothermal amplification for detection of influenza virus. Enzyme Microb Technol. 2025 Apr 7;188:110653. Abstract
submitted by kickingbird at Apr, 13, 2025 from Enzyme Microb Technol. 2025 Apr 7;188:110653 (via https://www.sciencedirect.com/science/article/abs/pii/S01410)
Here, we describe a lateral flow biosensor capable of detecting H1N1 virus by integrating duplex-specific nuclease (DSN) and a novel isothermal amplification, two probe isothermal amplification (TPIA). ... Alene KA, Moore HC, Clements ACA, Gilmour B, Barth. Spatiotemporal patterns of influenza in Western Australia. Public Health Pract (Oxf). 2025 Mar 15;9:100602. Abstract
submitted by kickingbird at Apr, 12, 2025 from Public Health Pract (Oxf). 2025 Mar 15;9:100602 (via https://www.sciencedirect.com/science/article/pii/S266653522)
Background: Understanding the geospatial distribution of influenza infection and the risk factors associated with infection clustering can inform targeted preventive interventions. We conducted a geospatial ... Gorden PJ, Magstadt DR, Baker AL, Arruda BL, Bell. Viral Mastitis Associated with Influenza A in Dairy Cattle. Vet Clin North Am Food Anim Pract. 2025 Apr 7:S074. Abstract
submitted by kickingbird at Apr, 10, 2025 from Vet Clin North Am Food Anim Pract. 2025 Apr 7:S074 (via https://www.sciencedirect.com/science/article/abs/pii/S07490)
n early 2024, farmers in the southwestern United States described a mysterious disease outbreak causing acute illness and milk drop. Diagnostic investigations determined this syndrome to result from H5N1 ... Tan WX, Qin SY, Yang X, Li XM, Li JH, Cao H, Jiang. Global Prevalence and Distribution of H9 Subtype of Avian Influenza Viruses in Wild Birds: Literature Review with Meta-Analysis. Vector Borne Zoonotic Dis. 2025 Apr 9. Abstract
submitted by kickingbird at Apr, 10, 2025 from Vector Borne Zoonotic Dis. 2025 Apr 9 (via https://www.liebertpub.com/doi/10.1089/vbz.2024.0111)
Background: As a natural accelerator of highly pathogenic avian influenza in wild birds, the H9 subtype of avian influenza poses a substantial threat to both humans and the poultry industry. A comprehensive ... Liu X, Balligand T, Le Gall C, Ploegh HL. A monoclonal anti-hemagglutinin stem antibody modified with zanamivir protects against both influenza A and B viruses. Proc Natl Acad Sci U S A. 2025 Apr 15;122(15):e242. Abstract
submitted by kickingbird at Apr, 9, 2025 from Proc Natl Acad Sci U S A. 2025 Apr 15;122(15):e242 (via https://www.pnas.org/doi/10.1073/pnas.2424889122)
Influenza remains a significant public health threat. Both monoclonal antibodies and small-molecule inhibitors can target the influenza surface glycoproteins hemagglutinin (HA) or neuraminidase (NA) for ... Xu S, Liu Y, Luo C, Zhou M, Wang K, Xie Q, Zhang Q. Identification and characterization of a broadly neutralizing and protective nanobody against the HA1 domain of H5 avian influenza virus hemagglutinin. J Virol. 2025 Apr 7:e0209024. Abstract
submitted by kickingbird at Apr, 8, 2025 from J Virol. 2025 Apr 7:e0209024 (via https://journals.asm.org/doi/10.1128/jvi.02090-24)
The highly pathogenic avian influenza viruses (HPAIVs) of subtype H5, particularly those of the currently circulating clades 2.3.2.1 and 2.3.4.4, are largely responsible for the sporadic human infections ... Zhang H, Chen X, Liu D, Liu X, Ge Y, Sun Y, Zhang. Immunogenicity and protective efficacy of an inactivated bivalent vaccine containing two recombinant H1N1 and H3N2 swine influenza virus strains. Cell Mol Life Sci. 2025 Apr 7;82(1):150. Abstract
submitted by kickingbird at Apr, 8, 2025 from Cell Mol Life Sci. 2025 Apr 7;82(1):150 (via https://link.springer.com/article/10.1007/s00018-025-05674-0)
The wild-type H1N1 and H3N2 swine influenza virus (SIV) strains are unsuitable for vaccine production because of high lethality in chicken embryos and low reproductive titers. This study developed recombinant ... Wang, P., Fu, J., Cheng, L. et al. Neutralizing monoclonal antibodies as effective therapeutics and prophylactics against lethal H10N7 avian influenza infection in a mouse model. Vet Res 56, 75 (2025). Abstract
submitted by kickingbird at Apr, 7, 2025 from Vet Res 56, 75 (2025) (via https://link.springer.com/article/10.1186/s13567-025-01504-0)
The H10 subtype of avian influenza virus (AIV) is widespread in poultry worldwide and poses a significant threat to animal health. With the emergence of sporadic and fatal cases in humans infected with ... Hu Z, Ai H, Wang Z, Huang S, Sun H, Xuan X, Chen M. Impact of inactivated vaccine on transmission and evolution of H9N2 avian influenza virus in chickens. NPJ Vaccines. 2025 Apr 4;10(1):67. Abstract
submitted by kickingbird at Apr, 7, 2025 from NPJ Vaccines. 2025 Apr 4;10(1):67 (via https://www.nature.com/articles/s41541-025-01115-y)
H9N2 avian influenza virus (AIV) is endemic in poultry worldwide and increasingly zoonotic. Despite the long-term widespread use of inactivated vaccines, H9N2 AIVs remain dominant in chicken flocks. We ... 6502 items, 20/Page, Page[32/326][|<<] [|<] [31] [32] [33] [34] [35] [36] [37] [38] [39] [40] [>|] [>>|] |
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