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2024-7-17 5:23:35
Article

Liang Y. Pathogenicity and virulence of influenza. Virulence. 2023 Dec;14(1):2223057.  Abstract  
submitted by kickingbird at Jun, 21, 2023 from Virulence. 2023 Dec;14(1):2223057 (via https://www.tandfonline.com/doi/full/10.1080/21505594.2023.2)
Influenza viruses, including four major types (A, B, C, and D), can cause mild-to-severe and lethal diseases in humans and animals. Influenza viruses evolve rapidly through antigenic drift (mutation) and ...

Rafique S, Rashid F, Mushtaq S, Ali A, Li M, Luo S. Global review of the H5N8 avian influenza virus subtype. Front Microbiol. 2023 Jun 2;14:1200681.  Abstract  
submitted by kickingbird at Jun, 20, 2023 from Front Microbiol. 2023 Jun 2;14:1200681 (via https://www.frontiersin.org/articles/10.3389/fmicb.2023.1200)
Orthomyxoviruses are negative-sense, RNA viruses with segmented genomes that are highly unstable due to reassortment. The highly pathogenic avian influenza (HPAI) subtype H5N8 emerged in wild birds in ...

Fereidouni S, Starick E, Karamendin K, Genova CD,. Genetic characterization of a new candidate hemagglutinin subtype of influenza A viruses. Emerg Microbes Infect. 2023 Jun 19:2225645.  Abstract  
submitted by kickingbird at Jun, 20, 2023 from Emerg Microbes Infect. 2023 Jun 19:2225645 (via https://www.tandfonline.com/doi/full/10.1080/22221751.2023.2)
Avian influenza viruses (AIV) have been classified on the basis of 16 subtypes of hemagglutinin (HA) and 9 subtypes of neuraminidase. Here we describe genomic evidence for a new candidate HA subtype, nominally ...

Arcos S, Han AX, Te Velthuis AJW, Russell CA, Laur. Mutual information networks reveal evolutionary relationships within the influenza A virus polymerase. Virus Evol. 2023 May 27;9(1):vead037.  Abstract  
submitted by kickingbird at Jun, 16, 2023 from Virus Evol. 2023 May 27;9(1):vead037 (via https://academic.oup.com/ve/article/9/1/vead037/7181271)
The influenza A virus (IAV) RNA polymerase is an essential driver of IAV evolution. Mutations that the polymerase introduces into viral genome segments during replication are the ultimate source of genetic ...

Ferreri LM, Carnaccini S, Olivera V, Pereda A, Raj. South American H4N2 influenza A virus improved replication in chicken trachea after low number of passages. Front Vet Sci. 2023 May 31;10:1182550..  Abstract  
submitted by kickingbird at Jun, 16, 2023 from Front Vet Sci. 2023 May 31;10:1182550. (via https://www.frontiersin.org/articles/10.3389/fvets.2023.1182)
Introduction of influenza A viruses (FLUAV) into poultry from waterfowl is frequent, producing economic burden and increasing the probability of human infections. We have previously described the presence ...

Rosone F, Bonfante F, Sala MG, Maniero S, Cersini. Seroconversion of a Swine Herd in a Free-Range Rural Multi-Species Farm against HPAI H5N1 2.3.4.4b Clade Virus. Microorganisms. 2023 Apr 28;11(5):1162.  Abstract  
submitted by kickingbird at Jun, 15, 2023 from Microorganisms. 2023 Apr 28;11(5):1162 (via https://www.mdpi.com/2076-2607/11/5/1162)
Starting from October 2021, several outbreaks of highly pathogenic avian influenza virus (HPAIV) subtype H5N1 were reported in wild and domestic birds in Italy. Following the detection of an HPAIV in a ...

Saim-Mamoun A, Carbonneau J, Rhéaume C, Abed Y, Bo. Viral Fitness of Baloxavir-Resistant Recombinant Influenza B/Victoria- and B/Yamagata-like Viruses Harboring the I38T PA Change, In Vitro, Ex Vivo and in Guinea Pigs. Microorganisms. 2023 Apr 22;11(5):1095.  Abstract  
submitted by kickingbird at Jun, 15, 2023 from Microorganisms. 2023 Apr 22;11(5):1095 (via https://www.mdpi.com/2076-2607/11/5/1095)
Seasonal influenza A and B viruses may cause severe infections requiring therapeutic interventions. Baloxavir, the latest antiviral drug approved against those infections, targets the endonuclease activity ...

Kwon JH, Bertran K, Lee DH, Criado MF, Killmaster. Diverse infectivity, transmissibility, and pathobiology of clade 2.3.4.4 H5Nx highly pathogenic avian influenza viruses in chickens. Emerg Microbes Infect. 2023 Dec;12(1):2218945.  Abstract  
submitted by kickingbird at Jun, 14, 2023 from Emerg Microbes Infect. 2023 Dec;12(1):2218945 (via https://www.tandfonline.com/doi/full/10.1080/22221751.2023.2)
Clade 2.3.4.4 Eurasian lineage H5Nx highly pathogenic avian influenza virus (HPAIV) has become the globally dominant clade and caused global outbreaks since 2014. The clade 2.3.4.4 viruses have evolved ...

Hanula R, Bortolussi-Courval é, Mendel A, Ward BJ,. Evaluation of Oseltamivir Used to Prevent Hospitalization in Outpatients With Influenza: A Systematic Review and Meta-analysis. JAMA Intern Med. 2023 Jun 12..  Abstract  
submitted by kickingbird at Jun, 13, 2023 from JAMA Intern Med. 2023 Jun 12. (via https://jamanetwork.com/journals/jamainternalmedicine/fullar)
Importance: Despite widespread use, summary evidence from prior meta-analyses has contradictory conclusions regarding whether oseltamivir decreases the risk of hospitalization when given to outpatients. ...

Tosheva II, Saygan KS, Mijnhardt SM, Russell CJ, F. Hemagglutinin stability as a key determinant of influenza A virus transmission via air. Curr Opin Virol. 2023 Jun 10;61:101335.  Abstract  
submitted by kickingbird at Jun, 13, 2023 from Curr Opin Virol. 2023 Jun 10;61:101335 (via https://www.sciencedirect.com/science/article/pii/S187962572)
To cause pandemics, zoonotic respiratory viruses need to adapt to replication in and spread between humans, either via (indirect or direct) contact or through the air via droplets and aerosols. To render ...

Wang K, Gong M, Zhao S, Lai C, Zhao L, Cheng S, Xi. A novel lncRNA DFRV plays a dual function in influenza A virus infection. Front Microbiol. 2023 May 25;14:1171423.  Abstract  
submitted by kickingbird at Jun, 12, 2023 from Front Microbiol. 2023 May 25;14:1171423 (via https://www.frontiersin.org/articles/10.3389/fmicb.2023.1171)
Long noncoding RNAs (lncRNAs) have been associated with a variety of biological activities, including immune responses. However, the function of lncRNAs in antiviral innate immune responses are not fully ...

Gass JD Jr, Hill NJ, Damodaran L, Naumova EN, Nutt. Ecogeographic Drivers of the Spatial Spread of Highly Pathogenic Avian Influenza Outbreaks in Europe and the United States, 2016-Early 2022. Int J Environ Res Public Health. 2023 Jun 1;20(11).  Abstract  
submitted by kickingbird at Jun, 11, 2023 from Int J Environ Res Public Health. 2023 Jun 1;20(11) (via https://www.mdpi.com/1660-4601/20/11/6030)
H5Nx highly pathogenic avian influenza (HPAI) viruses of clade 2.3.4.4 have caused outbreaks in Europe among wild and domestic birds since 2016 and were introduced to North America via wild migratory birds ...

Chen P, Jin Z, Peng L, Zheng Z, Cheung YM, Guan J,. Characterization of an Emergent Chicken H3N8 Influenza Virus in Southern China: a Potential Threat to Public Health. J Virol. 2023 Jun 8:e0043423.  Abstract  
submitted by kickingbird at Jun, 9, 2023 from J Virol. 2023 Jun 8:e0043423 (via https://journals.asm.org/doi/10.1128/jvi.00434-23)
Although influenza A viruses of several subtypes have occasionally infected humans, to date only those of the H1, H2, and H3 subtypes have led to pandemics and become established in humans. The detection ...

Zhou Y, Zhang S, Wang B, Ran Y, Tu S, Lin Z, Jin M. Proliferating cell nuclear antigen impairs the nuclear import of influenza A virus PB2 and suppresses virus replication. J Med Virol. 2023 Jun;95(6):e28849.  Abstract  
submitted by kickingbird at Jun, 8, 2023 from J Med Virol. 2023 Jun;95(6):e28849 (via https://pubmed.ncbi.nlm.nih.gov/37282768/)
The genome of Influenza A virus (IAV) transcribes and replicates in the nucleus of cells and the viral ribonucleoprotein (vRNP) complex plays an important role in viral replication. As a major component ...

Stevens L, de Buyl S, Mognetti BM. The sliding motility of the bacilliform virions of Influenza A viruses. Soft Matter. 2023 Jun 6.  Abstract  
submitted by kickingbird at Jun, 7, 2023 from Soft Matter. 2023 Jun 6 (via https://pubs.rsc.org/en/content/articlelanding/2023/SM/D3SM0)
Influenza A virus (IAV) infection relies on the action of the hemagglutinin (HA) and neuraminidase (NA) membrane proteins. The HA ligands anchor the IAV virion to the cell's surface by binding the sialic ...

Yehia N, Rabie N, Adel A, Mossad Z, Nagshabandi MK. Differential replication characteristic of reassortant avian influenza A viruses H5N8 clade 2.3.4.4b in Madin-Darby canine kidney cell. Poult Sci. 2023 Mar 29;102(7):102685.  Abstract  
submitted by kickingbird at Jun, 4, 2023 from Poult Sci. 2023 Mar 29;102(7):102685 (via https://www.sciencedirect.com/science/article/pii/S003257912)
Late in 2016, multiple reassortant highly pathogenic (HP) avian influenza virus (AIVs) H5N8 was detected. AIVs infect different isolated hosts with a specific viral tropism. In the current study, the whole ...

Wang C, Honce R, Salvatore M, Chow D, Randazzo D,. Influenza Defective Interfering Virus Promotes Multiciliated Cell Differentiation and Reduces the Inflammatory Response in Mice. J Virol. 2023 May 31:e0049323.  Abstract  
submitted by kickingbird at Jun, 2, 2023 from J Virol. 2023 May 31:e0049323 (via https://journals.asm.org/doi/10.1128/jvi.00493-23)
Influenza defective interfering (DI) viruses have long been considered promising antiviral candidates because of their ability to interfere with replication-competent viruses and induce antiviral immunity. ...

Meng B, Li H, Feng C, Guo W, Feng Y, Zhu D, Chen H. Emergence of a novel reassortant H3N6 canine influenza virus. Front Microbiol. 2023 May 11;14:1186869.  Abstract  
submitted by kickingbird at May, 31, 2023 from Front Microbiol. 2023 May 11;14:1186869 (via https://www.frontiersin.org/articles/10.3389/fmicb.2023.1186)
Although the natural hosts of avian influenza viruses (AIVs) are wild birds, multiple subtypes of AIVs have established epidemics in numerous mammals due to their cross-species spillover. Replication and ...

Nico Halwe, etc al. The bat-borne influenza A virus H9N2 exhibits a set of unexpected pre-pandemic features. Research Square.  Abstract  
submitted by kickingbird at May, 29, 2023 from Research Square (via https://www.researchsquare.com/article/rs-2937503/v1)
An Old-World bat H9N2 influenza A virus (IAV) identified in Egypt exhibits high replication and transmission potential in ferrets, efficient infection of human lung explant cultures and marked escape from ...

Schuele C, Schmeisser F, Orr M, Meseda CA, Vasudev. Neutralizing and protective murine monoclonal antibodies to the hemagglutinin of influenza H5 clades 2.3.2.1 and 2.3.4.4. Influenza Other Respir Viruses. 2023 May;17(5):e13.  Abstract  
submitted by kickingbird at May, 29, 2023 from Influenza Other Respir Viruses. 2023 May;17(5):e13 (via https://onlinelibrary.wiley.com/doi/10.1111/irv.13152)
Background: Highly pathogenic avian H5 influenza viruses have spread and diversified genetically and antigenically into multiple clades and subclades. Most isolates of currently circulating H5 viruses ...

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