Song W, Zhao L, Liu S, Jia Y, Ma L, Liao M, Dai M. Analysis of H5N8 influenza virus infection in chicken with mApple reporter genes in vivo and in vitro. Vet Microbiol. 2024 Mar 11;292:110052. Abstract
submitted by kickingbird at Mar, 18, 2024 from Vet Microbiol. 2024 Mar 11;292:110052 (via https://www.sciencedirect.com/science/article/abs/pii/S03781)
H5N8 highly pathogenic avian influenza virus (HPAIV) has caused huge losses to the global poultry industry and critically threatens public health. Chickens are the important host for the transmission. ... Lagan P, Hamil M, Cull S, Hanrahan A, Wregor RM, L. Swine influenza A virus infection dynamics and evolution in intensive pig production systems. Virus Evol. 2024 Feb 27;10(1):veae017. Abstract
submitted by kickingbird at Mar, 16, 2024 from Virus Evol. 2024 Feb 27;10(1):veae017 (via https://academic.oup.com/ve/article/10/1/veae017/7615508)
Swine influenza A virus (swIAV) is one of the main viral pathogens responsible for respiratory disease in farmed pigs. While outbreaks are often epidemic in nature, increasing reports suggest that continuous, ... Kim HJ, Han CW, Jeong MS, Jang SB. Cryo-EM structure of Influenza A virus NS1 and antiviral protein kinase PKR complex. Biochem Biophys Res Commun. 2024 Mar 5;706:149728. Abstract
submitted by kickingbird at Mar, 16, 2024 from Biochem Biophys Res Commun. 2024 Mar 5;706:149728 (via https://www.sciencedirect.com/science/article/abs/pii/S00062)
Influenza A virus is the cause of a widespread human disease with high morbidity and mortality rates. The influenza virus encodes non-structural protein 1 (NS1), an exceedingly multifunctional virulence ... Arruda B, Baker ALV, Buckley A, Anderson TK, Torch. Divergent Pathogenesis and Transmission of Highly Pathogenic Avian Influenza A(H5N1) in Swine. Emerg Infect Dis. 2024 Mar 13;30(4). Abstract
submitted by kickingbird at Mar, 15, 2024 from Emerg Infect Dis. 2024 Mar 13;30(4) (via https://pubmed.ncbi.nlm.nih.gov/38478379/)
Highly pathogenic avian influenza (HPAI) viruses have potential to cross species barriers and cause pandemics. Since 2022, HPAI A(H5N1) belonging to the goose/Guangdong 2.3.4.4b hemagglutinin phylogenetic ... Heindl MR, Rupp A-L, Schwerdtner M, Bestle D, Harb. ACE2 acts as a novel regulator of TMPRSS2-catalyzed proteolytic activation of influenza A virus in airway cells. J Virol. 2024 Mar 12:e0010224. Abstract
submitted by kickingbird at Mar, 13, 2024 from J Virol. 2024 Mar 12:e0010224 (via https://journals.asm.org/doi/10.1128/jvi.00102-24)
The transmembrane serine protease 2 (TMPRSS2) activates the outer structural proteins of a number of respiratory viruses including influenza A virus (IAV), parainfluenza viruses, and various coronaviruses ... Spruit CM, Palme DI, Li T, Ríos Carrasco M, Gabarr. Complex N-glycans are important for interspecies transmission of H7 influenza A viruses. J Virol. 2024 Mar 12:e0194123. Abstract
submitted by kickingbird at Mar, 13, 2024 from J Virol. 2024 Mar 12:e0194123 (via https://journals.asm.org/doi/10.1128/jvi.01941-23)
Influenza A viruses (IAVs) can overcome species barriers by adaptation of the receptor-binding site of the hemagglutinin (HA). To initiate infection, HAs bind to glycan receptors with terminal sialic acids, ... Wen F, Yan Z, Chen G, Chen Y, Wang N, Li Z, Guo J,. Recent H9N2 avian influenza virus lost hemagglutination activity due to a K141N substitution in hemagglutinin. J Virol. 2024 Mar 11:e0024824. Abstract
submitted by kickingbird at Mar, 12, 2024 from J Virol. 2024 Mar 11:e0024824 (via https://journals.asm.org/doi/10.1128/jvi.00248-24)
The H9N2 avian influenza virus (AIV) represents a significant risk to both the poultry industry and public health. Our surveillance efforts in China have revealed a growing trend of recent H9N2 AIV strains ... Kim JY, Jeong S, Kim DW, Lee DW, Lee DH, Kim D, Kw. Genomic epidemiology of highly pathogenic avian influenza A (H5N1) virus in wild birds in South Korea during 2021-2022: Changes in viral epidemic patterns. Virus Evol. 2024 Feb 7;10(1):veae014.. Abstract
submitted by kickingbird at Mar, 10, 2024 from Virus Evol. 2024 Feb 7;10(1):veae014. (via https://academic.oup.com/ve/article/10/1/veae014/7606456)
Clade 2.3.4.4b highly pathogenic avian influenza A (HPAI) viruses have been detected in wild birds worldwide, causing recurrent outbreaks since 2016. During the winter of 2021-2022, we detected one H5N8 ... Mao Q, Li Z, Li Y, Zhang Y, Liu S, Yin X, Peng C,. H5N1 high pathogenicity avian influenza virus in migratory birds exhibiting low pathogenicity in mallards increases its risk of transmission and spread in poultry. Vet Microbiol. 2024 Mar 2;292:110038. Abstract
submitted by kickingbird at Mar, 10, 2024 from Vet Microbiol. 2024 Mar 2;292:110038 (via https://www.sciencedirect.com/science/article/abs/pii/S03781)
In 2020, an H5N1 avian influenza virus of clade 2.3.4.4b was detected in Europe for the first time and was spread throughout the world by wild migratory birds, resulting in the culling of an unprecedented ... Lim WW, Shuo F, Wong SS, Sullivan SG, Cowling BJ. Hemagglutination inhibition antibody titers mediate influenza vaccine efficacy against symptomatic influenza A(H1N1), A(H3N2), and B/Victoria infections. J Infect Dis. 2024 Mar 7:jiae122. Abstract
submitted by kickingbird at Mar, 8, 2024 from J Infect Dis. 2024 Mar 7:jiae122 (via https://academic.oup.com/jid/advance-article-abstract/doi/10)
Background: The hemagglutination inhibition antibody (HAI) titer mediates only a part of vaccine-induced protection against influenza virus infections. Using causal mediation analysis, we quantified the ... Tan M, Zhang Y, Bo H, Li X, Zou S, Yang L, Liu J,. Rapid adaptive substitution of L226Q in HA protein increases the pathogenicity of H9N2 viruses in mice. Infect Med (Beijing). 2024 Feb 13;3(1):100090. Abstract
submitted by kickingbird at Mar, 7, 2024 from Infect Med (Beijing). 2024 Feb 13;3(1):100090 (via https://www.sciencedirect.com/science/article/pii/S2772431X2)
Background: Since the first human infection with H9N2 virus was reported in 1998, the number of cases of H9N2 infection has exceeded one hundred by 2021. However, there is no systematic description of ... Aracena KA, Lin YL, Luo K, Pacis A, Gona S, Mu Z,. Epigenetic variation impacts individual differences in the transcriptional response to influenza infection. Nat Genet. 2024 Feb 29. Abstract
submitted by kickingbird at Mar, 3, 2024 from Nat Genet. 2024 Feb 29 (via https://www.nature.com/articles/s41588-024-01668-z)
Humans display remarkable interindividual variation in their immune response to identical challenges. Yet, our understanding of the genetic and epigenetic factors contributing to such variation remains ... Ding X, Liu J, Jiang T, Wu A. Transmission restriction and genomic evolution co-shape the genetic diversity patterns of influenza A virus. Virol Sin. 2024 Feb 27:S1995-820X(24)00025-7. Abstract
submitted by kickingbird at Mar, 1, 2024 from Virol Sin. 2024 Feb 27:S1995-820X(24)00025-7 (via https://www.sciencedirect.com/science/article/pii/S1995820X2)
Influenza A virus (IAV) shows an extensive host range and rapid genomic variations, leading to continuous emergence of novel viruses with significant antigenic variations and the potential for cross-species ... Zhang M, Liu M, Chen H, Qiu T, Jin X, Fu W, Teng Q. PB2 residue 473 contributes to the mammalian virulence of H7N9 avian influenza virus by modulating viral polymerase activity via ANP32A. J Virol. 2024 Feb 29:e0194423. Abstract
submitted by kickingbird at Mar, 1, 2024 from J Virol. 2024 Feb 29:e0194423 (via https://journals.asm.org/doi/10.1128/jvi.01944-23)
Since the first human infection reported in 2013, H7N9 avian influenza virus (AIV) has been regarded as a serious threat to human health. In this study, we sought to identify the virulence determinant ... Yang R, Pan M, Guo J, Huang Y, Zhang QC, Deng T, W. Mapping of the influenza A virus genome RNA structure and interactions reveals essential elements of viral replication. Cell Rep. 2024 Feb 27;43(3):113833. Abstract
submitted by kickingbird at Feb, 29, 2024 from Cell Rep. 2024 Feb 27;43(3):113833 (via https://www.cell.com/cell-reports/fulltext/S2211-1247(24)001)
Influenza A virus (IAV) represents a constant public health threat. The single-stranded, segmented RNA genome of IAV is replicated in host cell nuclei as a series of 8 ribonucleoprotein complexes (vRNPs) ... Han J, Chang W, Fang J, Hou X, Li Z, Wang J, Deng. The H9N2 avian influenza virus increases APEC adhesion to oviduct epithelia by viral NS1 protein-mediated activation of the TGF-β pathway. J Virol. 2024 Feb 28:e0151223. Abstract
submitted by kickingbird at Feb, 29, 2024 from J Virol. 2024 Feb 28:e0151223 (via https://journals.asm.org/doi/10.1128/jvi.01512-23)
Avian influenza A (H9N2) avian influenza is a low-pathogenic avian influenza circulating in poultry and wild birds worldwide and frequently contributes to chicken salpingitis that is caused by avian pathogenic ... de Bruin ACM, Spronken MI, Kok A, Rosu ME, de Meul. Species-specific emergence of H7 highly pathogenic avian influenza virus is driven by intrahost selection differences between chickens and ducks. PLoS Pathog. 2024 Feb 26;20(2):e1011942. Abstract
submitted by kickingbird at Feb, 27, 2024 from PLoS Pathog. 2024 Feb 26;20(2):e1011942 (via https://journals.plos.org/plospathogens/article?id=10.1371/j)
Highly pathogenic avian influenza viruses (HPAIVs) cause severe hemorrhagic disease in terrestrial poultry and are a threat to the poultry industry, wild life, and human health. HPAIVs arise from low pathogenic ... Gu C, Fan S, Dahn R, Babujee L, Chiba S, Guan L, M. Characterization of a human H3N8 influenza virus. EBioMedicine. 2024 Feb 25;101:105034. Abstract
submitted by kickingbird at Feb, 27, 2024 from EBioMedicine. 2024 Feb 25;101:105034 (via https://www.thelancet.com/journals/ebiom/article/PIIS2352-39)
Background: In 2022 and 2023, novel reassortant H3N8 influenza viruses infected three people, marking the first human infections with viruses of this subtype.Methods: Here, we generated one of these viruses ... Ranum JN, Ledwith MP, Alnaji FG, Diefenbacher M, O. Cryptic proteins translated from deletion-containing viral genomes dramatically expand the influenza virus proteome. Nucleic Acids Res. 2024 Feb 26:gkae133. Abstract
submitted by kickingbird at Feb, 27, 2024 from Nucleic Acids Res. 2024 Feb 26:gkae133 (via https://academic.oup.com/nar/advance-article/doi/10.1093/nar)
Productive infections by RNA viruses require faithful replication of the entire genome. Yet many RNA viruses also produce deletion-containing viral genomes (DelVGs), aberrant replication products with ... Chen W, Ma T, Liu S, Zhong Y, Yu H, Shu J, Wang X,. N-Glycan Profiles of Neuraminidase from Avian Influenza Viruses. Viruses. 2024 Jan 26;16(2):190. Abstract
submitted by kickingbird at Feb, 25, 2024 from Viruses. 2024 Jan 26;16(2):190 (via https://www.mdpi.com/1999-4915/16/2/190)
The cleavage of sialic acids by neuraminidase (NA) facilitates the spread of influenza A virus (IV) descendants. Understanding the enzymatic activity of NA aids research into the transmission of IVs. An ... 5581 items, 20/Page, Page[25/280][|<<] [|<] [21] [22] [23] [24] [25] [26] [27] [28] [29] [30] [>|] [>>|] |
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