AEFFNER F, Woods PS, Davis IC. Activation of A1-adenosine Receptors Promotes Leukocyte Recruitment to the Lung and Attenuates Acute Lung Injury in Mice Infected with Influenza A/WSN/33 (H1N1) Virus. J Virol. 2014 Jun 25. pii: JVI.01068-14. Abstract
submitted by kickingbird at Jun, 29, 2014 from J Virol. 2014 Jun 25. pii: JVI.01068-14 (via http://www.ncbi.nlm.nih.gov/pubmed/24965449)
We have shown that bronchoalveolar epithelial A1-adenosine receptors (A1-AdoR) are activated in influenza A virus-infected mice. Alveolar macrophages and neutrophils also express A1-AdoRs and we hypothesized ... OHKURA T, Momose F, Ichikawa R, Takeuchi K, et al. Influenza A virus hemagglutinin and neuraminidase mutually accelerate their apical targeting through clustering of lipid rafts. J Virol. 2014 Jun 25. pii: JVI.00586-14. Abstract
submitted by kickingbird at Jun, 29, 2014 from J Virol. 2014 Jun 25. pii: JVI.00586-14 (via http://www.ncbi.nlm.nih.gov/pubmed/24965459)
In polarized epithelial cells, influenza A virus hemagglutinin (HA) and neuraminidase (NA) are intrinsically associated with lipid rafts and target the apical plasma membrane for viral assembly and budding. ... WU NC, Young AP, Al-Mawsawi LQ, Olson CA, et al. High-throughput identification of loss-of-function mutations for anti-interferon activity in influenza A virus NS segment. J Virol. 2014 Jun 25. pii: JVI.01494-14.. Abstract
submitted by kickingbird at Jun, 29, 2014 from J Virol. 2014 Jun 25. pii: JVI.01494-14. (via http://www.ncbi.nlm.nih.gov/pubmed/24965464)
Viral proteins often display several functions which require multiple assays to dissect their genetic basis. Here, we describe a systematic approach to screen for loss-of-function mutations that confer ... NELSON MI, Wentworth DE, Culhane MR, Vincent AL, e. Introductions and evolution of human-origin seasonal influenza A viruses in multinational swine populations. J Virol. 2014 Jun 25. pii: JVI.01080-14. Abstract
submitted by kickingbird at Jun, 29, 2014 from J Virol. 2014 Jun 25. pii: JVI.01080-14 (via http://www.ncbi.nlm.nih.gov/pubmed/24965467)
The capacity of influenza A viruses to cross species barriers presents a continual threat to human and animal health. Knowledge of the human-swine interface is particularly important for understanding ... YEN HL, Zhou J, Choy KT, Sia SF, et al. The R292 K mutation that confers resistance to neuraminidase inhibitors leads to competitive fitness loss of A/Shanghai/1/2013 (H7N9) influenza virus in ferrets.. J Infect Dis. 2014 Jun 20. pii: jiu353. Abstract
submitted by kickingbird at Jun, 29, 2014 from J Infect Dis. 2014 Jun 20. pii: jiu353 (via http://www.ncbi.nlm.nih.gov/pubmed/24951824)
BACKGROUND:
?The neuraminidase (NA) inhibitors are the only licensed therapeutic option for human zoonotic H7N9 infections. An NA-R292 K mutation that confers broad-spectrum resistance to NA inhibitors ... WANG J, Li F, Sun R, Gao X, et al. Klebsiella pneumoniae Alleviates Influenza-Induced Acute Lung Injury via Limiting NK Cell Expansion. J Immunol. 2014 Jun 20. pii: 1303303.. Abstract
submitted by kickingbird at Jun, 29, 2014 from J Immunol. 2014 Jun 20. pii: 1303303. (via http://www.ncbi.nlm.nih.gov/pubmed/24951819)
A protective effect induced by bacterial preinfection upon a subsequent lethal influenza virus infection has been observed, but the underlying immune mechanisms have not yet been fully elucidated. In this ... HIRATA N, Suizu F, Matsuda-Lennikov M, Edamura T,. Inhibition of Akt kinase activity suppresses entry and replication of influenza virus. Biochem Biophys Res Commun. 2014 Jun 24.. Abstract
submitted by kickingbird at Jun, 29, 2014 from Biochem Biophys Res Commun. 2014 Jun 24. (via http://www.ncbi.nlm.nih.gov/pubmed/24971535)
The possibility of the pandemic spread of influenza viruses highlights the need for an effective cure for this life-threatening disease. Influenza A virus, belonging to a family of orthomyxoviruses, is ... YIN X, Zhao FR, Zhou DH, Wei P, et al. Serological report of pandemic and seasonal human influenza virus infection in dogs in southern China. Arch Virol. 2014 Jun 26.. Abstract
submitted by kickingbird at Jun, 29, 2014 from Arch Virol. 2014 Jun 26. (via http://www.ncbi.nlm.nih.gov/pubmed/24965232)
From January to July 2012, we looked for evidence of subclinical A (H1N1) pdm09 and seasonal human influenza viruses infections in healthy dogs in China. Sera from a total of 1920 dogs were collected from ... Yondon M, Zayat B, Nelson MI, Heil GL, Anderson BD. Equine Influenza A(H3N8) Virus Isolated from Bactrian Camel, Mongolia. Emerg Infect Dis. 2014 Dec. Abstract
submitted by kickingbird at Jun, 28, 2014 from Emerg Infect Dis. 2014 Dec (via http://wwwnc.cdc.gov/eid/article/20/12/14-0435_article)
Because little is known about the ecology of influenza viruses in camels, 460 nasal swab specimens were collected from healthy (no overt illness) Bactrian camels in Mongolia during 2012. One specimen was ... Qi W, Zhou X, Shi W, Huang L, Xia W, Liu D, Li H,. Genesis of the novel human-infecting influenza A(H10N8) virus and potential genetic diversity of the virus in poultry, China. Euro Surveill. 2014;19(25):pii=20841. Abstract
submitted by kickingbird at Jun, 27, 2014 from Euro Surveill. 2014;19(25):pii=20841 (via http://www.eurosurveillance.org/ViewArticle.aspx?ArticleId=2)
Human infection with a novel influenza A(H10N8) virus was first described in China in December 2013. However, the origin and genetic diversity of this virus is still poorly understood. We performed a phylogenetic ... Wang D, Yang L, Gao R, Zhang X, Tan Y, Wu A, Zhu W. Genetic tuning of the novel avian influenza A(H7N9) virus during interspecies transmission, China, 2013. Euro Surveill. 2014;19(25):pii=20836. Abstract
submitted by kickingbird at Jun, 27, 2014 from Euro Surveill. 2014;19(25):pii=20836 (via http://www.eurosurveillance.org/ViewArticle.aspx?ArticleId=2)
A novel avian influenza A(H7N9) virus causing human infection emerged in February 2013 in China. To elucidate the mechanism of interspecies transmission, we compared the signature amino acids of avian ... Hu J, Zhu Y, Zhao B, Li J, Liu L, Gu K, Zhang W, S. Limited human-to-human transmission of avian influenza A(H7N9) virus, Shanghai, China, March to April 2013. Euro Surveill. 2014;19(25):pii=20838. Abstract
submitted by kickingbird at Jun, 27, 2014 from Euro Surveill. 2014;19(25):pii=20838 (via http://www.eurosurveillance.org/ViewArticle.aspx?ArticleId=2)
In April 2013, two members of one family were successively confirmed as cases of avian influenza A(H7N9) virus infection in Shanghai, China. Respiratory specimens from the two cases and their close contacts ... Xiao XC, Li KB, Chen ZQ, Di B, Yang ZC, Yuan J, Lu. Transmission of avian influenza A(H7N9) virus from father to child: a report of limited person-to-person transmission, Guangzhou, China, January 2014. Euro Surveill. 2014;19(25):pii=20837. Abstract
submitted by kickingbird at Jun, 27, 2014 from Euro Surveill. 2014;19(25):pii=20837 (via http://www.eurosurveillance.org/ViewArticle.aspx?ArticleId=2)
We investigated a possible person-to-person transmission within a family cluster of two confirmed influenza A(H7N9) patients in Guangzhou, China. The index case, a man in his late twenties, worked in a ... Herfst S, Fouchier R.. Epidemiological and genetic investigations of human-to-human transmission of zoonotic influenza viruses. Euro Surveill. 2014;19(25):pii=20840. Full Text
submitted by kickingbird at Jun, 27, 2014 from Euro Surveill. 2014;19(25):pii=20840 (via http://www.eurosurveillance.org/ViewArticle.aspx?ArticleId=2)
Of the over 1,400 species of infectious organisms known to be pathogenic to humans, 60% are zoonotic, i.e. transmissible from animals to humans [1]. We therefore continuously face the threat of newly emerging ... Chea N, Yi SD, Rith S, Seng H, Ieng V, Penh C, Mar. Two clustered cases of confirmed influenza A(H5N1) virus infection, Cambodia, 2011. Euro Surveill. 2014;19(25):pii=20839. Abstract
submitted by kickingbird at Jun, 27, 2014 from Euro Surveill. 2014;19(25):pii=20839 (via http://www.eurosurveillance.org/ViewArticle.aspx?ArticleId=2)
In February 2011, a mother and her child from Banteay Meanchey Province, Cambodia, were diagnosed, postmortem, with avian influenza A(H5N1) virus infection. A field investigation was conducted by teams ... LEVIN Y, Kochba E, Kenney R. Clinical evaluation of a novel microneedle device for intradermal delivery of an influenza vaccine: Are all delivery methods the same?. Vaccine. 2014 Jun 12. pii: S0264-410X(14)00368-5.. Abstract
submitted by kickingbird at Jun, 24, 2014 from Vaccine. 2014 Jun 12. pii: S0264-410X(14)00368-5. (via http://www.ncbi.nlm.nih.gov/pubmed/24930715)
The skin provides the largest immune barrier to infection and is a readily accessible site for vaccination, although intradermal (ID) injection can be challenging. The MicronJet? microneedle is a novel ... LI W, Chen H, Sutton T, Obadan A, et al. Interactions between the Influenza A Virus RNA Polymerase Components and Retinoic Acid-Inducible Gene I. J Virol. 2014 Jun 18. pii: JVI.01383-14. Abstract
submitted by kickingbird at Jun, 24, 2014 from J Virol. 2014 Jun 18. pii: JVI.01383-14 (via http://www.ncbi.nlm.nih.gov/pubmed/24942585)
The influenza A virus genome possesses eight negative-strand RNA segments in the form of viral ribonucleoprotein particles (vRNPs) in association with the three viral RNA polymerase subunits (PB2, PB1, ... CHEN H, Angel M, Li W, Finch C, et al. All-in-one bacmids: An efficient reverse genetics strategy for influenza A virus vaccines. J Virol. 2014 Jun 18. pii: JVI.01468-14. Abstract
submitted by kickingbird at Jun, 24, 2014 from J Virol. 2014 Jun 18. pii: JVI.01468-14 (via http://www.ncbi.nlm.nih.gov/pubmed/24942589)
Vaccination is the first line of defense against influenza infections, yet influenza vaccine production methods are slow, antiquated, and expensive to effectively reduce the virus' burden during epidemic ... PYO CW, Shin N, Jung KI, Choi JH, et al. Alteration of copper-zinc superoxide dismutase 1 expression by influenza A virus is correlated with virus replication.. Biochem Biophys Res Commun. 2014 Jun 16.. Abstract
submitted by kickingbird at Jun, 24, 2014 from Biochem Biophys Res Commun. 2014 Jun 16. (via http://www.ncbi.nlm.nih.gov/pubmed/24946209)
Viruses have evolved mechanisms designated to potentiate virus replication by modulating the physiological condition of host cells. The generation of reactive oxygen species (ROS) during infection with ... LALIME EN, Pekosz A. The R35 residue of the influenza A virus NS1 protein has minimal effects on nuclear localization but alters virus replication through disrupting protein dimerization. Virology. 2014 Jun;458-459:33-42.. Abstract
submitted by kickingbird at Jun, 22, 2014 from Virology. 2014 Jun;458-459:33-42. (via http://www.ncbi.nlm.nih.gov/pubmed/24928037)
The influenza A virus NS1 protein has a nuclear localization sequence (NLS) in the amino terminal region. This NLS overlaps sequences that are important for RNA binding as well as protein dimerization. ... 6502 items, 20/Page, Page[244/326][|<<] [|<] [241] [242] [243] [244] [245] [246] [247] [248] [249] [250] [>|] [>>|] |
Related Pages:
Browse by Category
Learn about the flu news, articles, events and more
Subscribe to the weekly F.I.C newsletter!
|
- 
