Li PQ, Zhang J, Muller CP, Chen JX, Yang ZF, Zhang. Development of a multiplex real-time polymerase chain reaction for the detection of influenza virus type A including H5 and H9 subtypes. Diagn Microbiol Infect Dis. 2008 Feb 22. Abstract
submitted by kickingbird at Mar, 1, 2008 from Diagn Microbiol Infect Dis. 2008 Feb 22 (via http://www.ncbi.nlm.nih.gov/pubmed/18296004?ordinalpos=29&it)
Avian influenza viruses (AIVs) are endemic in wild birds and, if transmitted to poultry, can cause serious economic losses. The aim of this study was to develop a multiplex real-time reverse transcriptase ... Choi JG, Lee YJ, Kim YJ, Lee EK, Jeong OM, Sung HW. An inactivated vaccine to control the current H9N2 low pathogenic avian influenza in Korea. J Vet Sci. 2008 Mar;9(1):67-74. Full Text
submitted by kickingbird at Mar, 1, 2008 from J Vet Sci. 2008 Mar;9(1):67-74 (via http://www.vetsci.org/2008/abstract/67a.html)
The H9N2 subtype low pathogenic avian influenza is one of the most prevalent avian diseases worldwide, and was first documented in 1996 in Korea. This disease caused serious economic loss in Korea's poultry ... Bertelli AA, Mannari C, Santi S, Filippi C, Miglio. Immunomodulatory activity of shikimic acid and quercitin in comparison with oseltamivir (Tamiflu) in an "in vitro" model. J Med Virol. 2008 Feb 22;80(4):741-745. Abstract
submitted by kickingbird at Mar, 1, 2008 from J Med Virol. 2008 Feb 22;80(4):741-745 (via http://www.ncbi.nlm.nih.gov/pubmed/18297698?ordinalpos=23&it)
The risk of an avian influenza pandemic has put oseltamivir (Tamiflu(R)) in the spotlight and has given rise to rumors that shikimic acid (SK), which is used for the synthesis of Tamiflu(R), possesses ... Townsend MB, Smagala JA, Dawson ED, Deyde V, Gubar. Detection of adamantane-resistant influenza on a microarray.. J Clin Virol. 2008 Feb 23. Abstract
submitted by kickingbird at Mar, 1, 2008 from J Clin Virol. 2008 Feb 23 (via http://www.ncbi.nlm.nih.gov/pubmed/18299250?ordinalpos=21&it)
BACKGROUND: Influenza A has the ability to rapidly mutate and become resistant to the commonly prescribed influenza therapeutics, thereby complicating treatment decisions. OBJECTIVE: To design a cost-effective ... Cannell JJ, Zasloff M, Garland CF, Scragg R, Giova. On the epidemiology of influenza. Virol J. 2008 Feb 25;5(1):29. Abstract
submitted by kickingbird at Mar, 1, 2008 from Virol J. 2008 Feb 25;5(1):29 (via http://www.virologyj.com/content/5/1/29)
ABSTRACT: The epidemiology of influenza swarms with incongruities, incongruities exhaustively detailed by the late British epidemiologist, Edgar Hope-Simpson. He was the first to propose a parsimonious ... Joo HM, He Y, Sangster MY. Broad dispersion and lung localization of virus-specific memory B cells induced by influenza pneumonia. Proc Natl Acad Sci U S A. 2008 Feb 25. Abstract
submitted by kickingbird at Mar, 1, 2008 from Proc Natl Acad Sci U S A. 2008 Feb 25 (via http://www.pnas.org/cgi/content/abstract/0800003105v1)
Although memory B cells (B(Mem)) contribute significantly to resistance to infection, B(Mem) population characteristics that may relate to protective efficacy have received little attention. Here, we report ... Singh N, Pandey A, Jayashankar L, Mittal SK. Bovine Adenoviral Vector-based H5N1 Influenza Vaccine Overcomes Exceptionally High Levels of Pre-existing Immunity Against Human Adenovirus. Mol Ther. 2008 Feb 26. Abstract
submitted by kickingbird at Mar, 1, 2008 from Mol Ther. 2008 Feb 26 (via http://www.ncbi.nlm.nih.gov/pubmed/18301400?ordinalpos=17&it)
Because of the high prevalence of adenovirus (Ad) infections in humans, it is believed that pre-existing Ad-neutralizing antibodies (vector immunity) may negatively impact the immune response to vaccine ... Leroux-Roels I, Bernhard R, Gérard P, Dramé M, Han. Broad Clade 2 Cross-Reactive Immunity Induced by an Adjuvanted Clade 1 rH5N1 Pandemic Influenza Vaccine. PLoS ONE. 2008 Feb 27;3(2):e1665.. Full Text
submitted by kickingbird at Mar, 1, 2008 from PLoS ONE. 2008 Feb 27;3(2):e1665. (via http://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pub)
BACKGROUND: The availability of H5N1 vaccines that can elicit a broad cross-protective immunity against different currently circulating clade 2 H5N1 viruses is a pre-requisite for the development of a ... Tecle T, White MR, Sorensen GL, Gantz D, Kacak N,. Critical role for crosslinking of trimeric lectin domains of surfactant protein D in antiviral activity against influenza A virus. Biochem J. 2008 Feb 27. Abstract
submitted by kickingbird at Mar, 1, 2008 from Biochem J. 2008 Feb 27 (via http://www.ncbi.nlm.nih.gov/pubmed/18302538?ordinalpos=12&it)
Collectins are multimeric host defense lectins with trimeric carbohydrate recognition domains (CRDs) and collagen and N-terminal domains that form higher order structures composed of four or more trimers. ... Nogusa S, Ritz BW, Kassim SH, Jennings SR, Gardner. Characterization of age-related changes in natural killer cells during primary influenza infection in mice. Mech Ageing Dev. 2008 Jan 20. Abstract
submitted by kickingbird at Mar, 1, 2008 from Mech Ageing Dev. 2008 Jan 20 (via http://www.ncbi.nlm.nih.gov/pubmed/18304606?ordinalpos=9&ito)
The current investigation examined the importance of natural killer (NK) cells during the innate immune response to primary influenza infection in young and aged mice. Young (6-8 weeks) and aged (22 months) ... Zhang J, Wang Q, Fang H, Xu W, Liu A, Du G. Design, synthesis, inhibitory activity, and SAR studies of hydrophobic p-aminosalicylic acid derivatives as neuraminidase inhibitors. Bioorg Med Chem. 2008 Jan 30. Abstract
submitted by kickingbird at Mar, 1, 2008 from Bioorg Med Chem. 2008 Jan 30 (via http://www.ncbi.nlm.nih.gov/pubmed/18304821?ordinalpos=8&ito)
A series of hydrophobic p-aminosalicylic acid derivatives containing a lipophilic side chain at C-2 and an amino or guanidine at C-5 were synthesized and evaluated for their ability to inhibit neuraminidase ... Wasilenko JL, Lee CW, Sarmento L, Spackman E, Kapc. NP, PB1 and PB2 viral genes contribute to altered replication of H5N1 avian influenza viruses in chickens. J Virol. 2008 Feb 27. Abstract
submitted by kickingbird at Mar, 1, 2008 from J Virol. 2008 Feb 27 (via http://www.ncbi.nlm.nih.gov/pubmed/18305037?ordinalpos=7&ito)
The virulence determinants for highly pathogenic avian influenza viruses are considered multigenic, although the best characterized virulence factor is the hemagglutinin cleavage site. The capability of ... Pasquato A, Seidah NG. The H5N1 Influenza Variant Fujian-Like Hemagglutinin Selected Following Vaccination Exhibits a Compromised Furin Cleavage : Neurological Consequences of Highly Pathogenic Fujian H5N1 Strains. J Mol Neurosci. 2008 Feb 28. Abstract
submitted by kickingbird at Mar, 1, 2008 from J Mol Neurosci. 2008 Feb 28 (via http://www.ncbi.nlm.nih.gov/pubmed/18306058?ordinalpos=2&ito)
The outbreak of H5N1 avian influenza strains infectious to human has dire neurological and pathological consequences. This led to the massive vaccination of host poultry, resulting in a Fujian-like variant ... HAN Jian-feng; NING Yi-bao; JIANG Tao-zhen; LI Nin. Rapid quantitative detection of H5 subtype avian influenza inactivated vaccine by real-time fluorescent PCR and exploration of vaccine efficacy by in vitro test. Chinese Journal of Microbiology and Immunology. Abstract
submitted by kickingbird at Feb, 26, 2008 from Chinese Journal of Microbiology and Immunology (via http://www.cnki.net)
Objective To establish a specific, sensitive, rapid method to detect virus gene of H5 sub- type inactivated vaccine and to analyze the correlation between the gene copy number and the HI antibody titer. ... HUANG Ping KE Chang-wen LI Hui ZOU Li-rong FANG Li. Variations and evolutions of NP genes of human avian H5N1 strains in Guangdong Province. Chinese Journal of Microbiology and Immunology. Abstract
submitted by kickingbird at Feb, 26, 2008 from Chinese Journal of Microbiology and Immunology (via http://www.cnki.net)
Objective To identify variation and revolution of NP genes of human avian HSNI influenza strains by analysis on sequences of NP gene.Methods NP gene of human avian H5N1 influenza in Guangdong was sequenced ... HAN Qing-gong; QIAO Chuan-ling etc.,al. Sequencing and eukaryotic expression of HA gene of H9N2 subtype influenza virus from swine. Chinese Journal of Preventive Veterinary Medicine. Abstract
submitted by kickingbird at Feb, 26, 2008 from Chinese Journal of Preventive Veterinary Medicine (via http://www.cnki.net)
HA gene of SW/ZhJ7/04 was amplified by RT-PCR,sequenced,and cloned into recombinant plasmid pCAGGS-HA. The 293T cells monolayer were transfected with plasmid pCAGGS-HA,expression of the HA protein was ... ZHONG Gong-xun; LI Yan-bing; PING Ji-hui;CHEN HL. Genetic analysis of the hemagglutinin(HA)and neuraminidase(NA)genes of H9N2 influenza viruses isolated from mainland China. Chinese Journal of Preventive Veterinary Medicine. Abstract
submitted by kickingbird at Feb, 26, 2008 from Chinese Journal of Preventive Veterinary Medicine (via http://www.cnki.net)
The H9N2 subtype of avian influenza viruses have widely circulated in mainland China since 1994.Previous studies revealed that the H9N2 viruses in mainland China formed multiple genotypes.The surface protein ... BERNSTEIN DI, Edwards KM, Dekker CL, Belshe R, et. Effects of Adjuvants on the Safety and Immunogenicity of an Avian Influenza H5N1 Vaccine in Adults. J Infect Dis. 2008 Feb 8. Abstract
submitted by kickingbird at Feb, 20, 2008 from J Infect Dis. 2008 Feb 8 (via http://www.ncbi.nlm.nih.gov/pubmed/18260764)
Background. ; Influenza A H5N1 viruses pose a significant threat to human health.
Methods.; We conducted a multicenter, randomized, double-blind study in 394 healthy adults. Subjects were randomly assigned ... WANG G, Zhan D, Li L, Lei F, et al. H5N1 avian influenza re-emergence of Lake Qinghai: phylogenetic and antigenic analyses of the newly isolated viruses and roles of migratory birds in virus circulation. J Gen Virol. 2008 Mar;89(Pt 3):697-702. Abstract
submitted by kickingbird at Feb, 20, 2008 from J Gen Virol. 2008 Mar;89(Pt 3):697-702 (via http://www.ncbi.nlm.nih.gov/pubmed/18272760)
Highly pathogenic avian influenza H5N1 virus has swept west across the globe and caused serious debates on the roles of migratory birds in virus circulation since the first large-scale outbreak in migratory ... TAKAHASHI T, Moriyama Y, Ikari A, Sugatani J, et a. Surface localization of the nuclear receptor CAR in influenza A virus-infected cells. Biochem Biophys Res Commun. 2008 Feb 7. Abstract
submitted by kickingbird at Feb, 20, 2008 from Biochem Biophys Res Commun. 2008 Feb 7 (via http://www.ncbi.nlm.nih.gov/pubmed/18261975)
Constitutive active/androstane receptor CAR is a member of the nuclear receptors which regulate transcription of xenobiotic metabolism enzymes. CAR is usually localized in the cytosol and nucleus. Here, ... 5584 items, 20/Page, Page[241/280][|<<] [|<] [241] [242] [243] [244] [245] [246] [247] [248] [249] [250] [>|] [>>|] |
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