Chan JJ, Tang YS, Lo CY, Shaw PC. Functional Importance of the Hydrophobic Residue 362 in Influenza A PB1 Subunit. Viruses. 2023 Jan 30;15(2):396. Abstract
submitted by kickingbird at Mar, 1, 2023 from Viruses. 2023 Jan 30;15(2):396 (via https://www.mdpi.com/1999-4915/15/2/396)
PB1, acting as the catalytic subunit of the influenza polymerase, has numerous sequentially and structurally conserved regions. It has been observed that the slight modification of residues in PB1 would ... Xu L, Ou J, Hu X, Zheng Y, Ye S, Zhong L, Lai Z, C. Identification of Two Isoforms of Canine Tetherin in Domestic Dogs and Characterization of Their Antiviral Activity against Canine Influenza Virus. Viruses. 2023 Jan 30;15(2):393. Abstract
submitted by kickingbird at Mar, 1, 2023 from Viruses. 2023 Jan 30;15(2):393 (via https://www.mdpi.com/1999-4915/15/2/393)
Canine influenza virus (CIV) significantly threatens the canine population and public health. Tetherin, an innate immune factor, plays an important role in the defense against pathogen invasion and has ... Liu Y, Wei Y, Zhou Z, Gu Y, Pang Z, Liao M, Sun H. Overexpression of TRIM16 Reduces the Titer of H5N1 Highly Pathogenic Avian Influenza Virus and Promotes the Expression of Antioxidant Genes through Regulating the SQSTM1-NRF2-KEAP1 Axis. Viruses. 2023 Jan 30;15(2):391. Abstract
submitted by kickingbird at Mar, 1, 2023 from Viruses. 2023 Jan 30;15(2):391 (via https://www.mdpi.com/1999-4915/15/2/391)
Oxidative stress plays a vital role in viral replication. Tripartite motif containing 16 (TRIM16) is involved in diverse cellular processes. However, the role of TRIM16 in oxidative stress induced by infection ... Zhang H, Han S, Wang B, Xing Y, Yuan G, Wang Y, Zh. Genetic Characterization and Pathogenesis of Avian Influenza Virus H3N8 Isolated from Chinese pond heron in China in 2021. Viruses. 2023 Jan 28;15(2):383. Abstract
submitted by kickingbird at Mar, 1, 2023 from Viruses. 2023 Jan 28;15(2):383 (via https://www.mdpi.com/1999-4915/15/2/383)
In October 2021, a wild bird-origin H3N8 influenza virus-A/Chinese pond heron/Jiangxi 5-1/2021 (H3N8)-was isolated from Chinese pond heron in China. Phylogenetic and molecular analyses were performed to ... Einav T, Kosikova M, Radvak P, Kuo YC, Kwon HJ, Xi. Mapping the Antibody Repertoires in Ferrets with Repeated Influenza A/H3 Infections: Is Original Antigenic Sin Really. Viruses. 2023 Jan 28;15(2):374. Abstract
submitted by kickingbird at Mar, 1, 2023 from Viruses. 2023 Jan 28;15(2):374 (via https://www.mdpi.com/1999-4915/15/2/374)
The influenza-specific antibody repertoire is continuously reshaped by infection and vaccination. The host immune response to contemporary viruses can be redirected to preferentially boost antibodies specific ... Souza CK, Kimble JB, Anderson TK, Arendsee ZW, Huf. Swine-to-Ferret Transmission of Antigenically Drifted Contemporary Swine H3N2 Influenza A Virus Is an Indicator of Zoonotic Risk to Humans. Viruses. 2023 Jan 24;15(2):331. Abstract
submitted by kickingbird at Mar, 1, 2023 from Viruses. 2023 Jan 24;15(2):331 (via https://www.mdpi.com/1999-4915/15/2/331)
Human-to-swine transmission of influenza A (H3N2) virus occurs repeatedly and plays a critical role in swine influenza A virus (IAV) evolution and diversity. Human seasonal H3 IAVs were introduced from ... Mettier J, Prompt C, Bruder E, Da Costa B, Chevali. Comparison of PB1-F2 Proximity Interactomes Reveals Functional Differences between a Human and an Avian Influenza Virus. Viruses. 2023 Jan 24;15(2):328. Abstract
submitted by kickingbird at Mar, 1, 2023 from Viruses. 2023 Jan 24;15(2):328 (via https://www.mdpi.com/1999-4915/15/2/328)
Most influenza viruses express the PB1-F2 protein which is regarded as a virulence factor. However, PB1-F2 behaves differently in avian and mammalian hosts, suggesting that this protein may be involved ... Baggio G, Filippini F, Righetto I. Comparative Surface Electrostatics and Normal Mode Analysis of High and Low Pathogenic H7N7 Avian Influenza Viruses. Viruses. 2023 Jan 21;15(2):305. Abstract
submitted by kickingbird at Mar, 1, 2023 from Viruses. 2023 Jan 21;15(2):305 (via https://www.mdpi.com/1999-4915/15/2/305)
Influenza A viruses are rarely symptomatic in wild birds, while representing a higher threat to poultry and mammals, where they can cause a variety of symptoms, including death. H5 and H7 subtypes of influenza ... Nagy A, Stará M, ?erníková L, Hofmannová L, Sedlák. Genotype Diversity, Wild Bird-to-Poultry Transmissions, and Farm-to-Farm Carryover during the Spread of the Highly Pathogenic Avian Influenza H5N1 in the Czech Republic in 2021/2022. Viruses. 2023 Jan 20;15(2):293. Abstract
submitted by kickingbird at Mar, 1, 2023 from Viruses. 2023 Jan 20;15(2):293 (via https://www.mdpi.com/1999-4915/15/2/293)
In 2021/2022, the re-emergence of highly pathogenic avian influenza (HPAI) occurred in Europe. The outbreak was seeded from two sources: resident and reintroduced viruses, which is unprecedented in the ... Takadate Y, Tsunekuni R, Kumagai A, Mine J, Kikuta. Different Infectivity and Transmissibility of H5N8 and H5N1 High Pathogenicity Avian Influenza Viruses Isolated from Chickens in Japan in the 2021/2022 Season. Viruses. 2023 Jan 17;15(2):265. Abstract
submitted by kickingbird at Mar, 1, 2023 from Viruses. 2023 Jan 17;15(2):265 (via https://www.mdpi.com/1999-4915/15/2/265)
H5N8 and H5N1 high pathogenicity avian influenza viruses (HPAIVs) caused outbreaks in poultry farms in Japan from November 2021 to May 2022. Hemagglutinin genes of these viruses belong to clade 2.3.4.4B ... Rehman S, Prasetya RR, Rahardjo K, Effendi MH, Ran. Whole-genome sequence and genesis of an avian influenza virus H5N1 isolated from a healthy chicken in a live bird market in Indonesia: accumulation of mammalian adaptation markers in avian hosts. PeerJ. 2023 Feb 21;11:e14917. Abstract
submitted by kickingbird at Feb, 28, 2023 from PeerJ. 2023 Feb 21;11:e14917 (via https://peerj.com/articles/14917/)
Background: Influenza A viruses are a major pathogen that causes significant clinical and economic harm to many animals. In Indonesia, the highly pathogenic avian influenza (HPAI) H5N1 virus has been endemic ... Duvvuri VR, Hicks JT, Damodaran L, Grunnill M, Bra. Comparing the transmission potential from sequence and surveillance data of 2009 North American influenza pandemic waves. Infect Dis Model. 2023 Feb 16;8(1):240-252. Abstract
submitted by kickingbird at Feb, 28, 2023 from Infect Dis Model. 2023 Feb 16;8(1):240-252 (via https://www.sciencedirect.com/science/article/pii/S246804272)
Technological advancements in phylodynamic modeling coupled with the accessibility of real-time pathogen genetic data are increasingly important for understanding the infectious disease transmission dynamics. ... Haw DJ, Biggerstaff M, Prasad P, Walker J, Grenfel. Using real-time data to guide decision-making during an influenza pandemic: A modelling analysis. PLoS Comput Biol. 2023 Feb 27;19(2):e1010893. Abstract
submitted by kickingbird at Feb, 28, 2023 from PLoS Comput Biol. 2023 Feb 27;19(2):e1010893 (via https://journals.plos.org/ploscompbiol/article?id=10.1371/jo)
Influenza pandemics typically occur in multiple waves of infection, often associated with initial emergence of a novel virus, followed (in temperate regions) by a resurgence accompanying the onset of the ... Li X, Xu Y, Li W, Che J, Zhao X, Cao R, Li X, Li S. Design, Synthesis, Biological Evaluation, and Molecular Dynamics Simulation of Influenza Polymerase PB2 Inhibitors. Molecules. 2023 Feb 15;28(4):1849. Abstract
submitted by kickingbird at Feb, 26, 2023 from Molecules. 2023 Feb 15;28(4):1849 (via https://www.mdpi.com/1420-3049/28/4/1849)
The PB2 subunit of the influenza RNA-dependent RNA polymerase (RdRp) has been identified as a promising target for the treatment of influenza. To expand the chemical space of the known influenza polymerase ... Ip HS, Uhm S, Killian ML, Torchetti MK. An Evaluation of Avian Influenza Virus Whole-Genome Sequencing Approaches Using Nanopore Technology. Microorganisms. 2023 Feb 19;11(2):529. Abstract
submitted by kickingbird at Feb, 26, 2023 from Microorganisms. 2023 Feb 19;11(2):529 (via https://www.mdpi.com/2076-2607/11/2/529)
As exemplified by the global response to the SARS-CoV-2 pandemic, whole-genome sequencing played an important role in monitoring the evolution of novel viral variants and provided guidance on potential ... Vreman S, Kik M, Germeraad E, Heutink R, Harders F. Zoonotic Mutation of Highly Pathogenic Avian Influenza H5N1 Virus Identified in the Brain of Multiple Wild Carnivore Species. Pathogens. 2023 Jan 20;12(2):168. Abstract
submitted by kickingbird at Feb, 26, 2023 from Pathogens. 2023 Jan 20;12(2):168 (via https://www.mdpi.com/2076-0817/12/2/168)
Wild carnivore species infected with highly pathogenic avian influenza (HPAI) virus subtype H5N1 during the 2021-2022 outbreak in the Netherlands included red fox (Vulpes vulpes), polecat (Mustela putorius), ... Tarasiuk K, Kycko A, ?wi?toń E, Bocian ?, Wyrostek. Homo- and Heterosubtypic Immunity to Low Pathogenic Avian Influenza Virus Mitigates the Clinical Outcome of Infection with Highly Pathogenic Avian Influenza H5N8 Clade 2.3.4.4.b in Captive Mallards (. Pathogens. 2023 Jan 30;12(2):217.. Abstract
submitted by kickingbird at Feb, 26, 2023 from Pathogens. 2023 Jan 30;12(2):217. (via https://www.mdpi.com/2076-0817/12/2/217)
In this study, we investigated the clinical response, viral shedding, transmissibility, pathologic lesions, and tropism of HPAIV Gs/Gd H5N8 subtype (clade 2.3.4.4b), following experimental infection of ... Braun KM, Haddock Iii LA, Crooks CM, Barry GL, Lal. Avian H7N9 influenza viruses are evolutionarily constrained by stochastic processes during replication and transmission in mammals. Virus Evol. 2023 Jan 19;9(1):vead004. Abstract
submitted by kickingbird at Feb, 24, 2023 from Virus Evol. 2023 Jan 19;9(1):vead004 (via https://academic.oup.com/ve/article/9/1/vead004/6991850)
H7N9 avian influenza viruses (AIVs) have caused over 1,500 documented human infections since emerging in 2013. Although wild-type H7N9 AIVs can be transmitted by respiratory droplets in ferrets, they have ... Aznar E, Casas I, González Praetorius A, Ruano Ram. Influenza A(H5N1) detection in two asymptomatic poultry farm workers in Spain, September to October 2022: suspected environmental contamination. Euro Surveill. 2023 Feb;28(8). Abstract
submitted by kickingbird at Feb, 24, 2023 from Euro Surveill. 2023 Feb;28(8) (via https://pubmed.ncbi.nlm.nih.gov/36820643/)
In autumn 2022, the Spanish Influenza National Reference Laboratory (NRL) confirmed the detection of influenza A(H5N1) in samples from two asymptomatic workers linked to an outbreak in a poultry farm in ... Gu M, Jiao J, Liu S, Zhao W, Ge Z, Cai K, Xu L, He. Monoclonal antibody targeting a novel linear epitope on nucleoprotein confers pan-reactivity to influenza A virus. Appl Microbiol Biotechnol. 2023 Feb 23:1–14.. Abstract
submitted by kickingbird at Feb, 24, 2023 from Appl Microbiol Biotechnol. 2023 Feb 23:1–14. (via https://link.springer.com/article/10.1007/s00253-023-12433-3)
Nucleoprotein (NP) functions crucially in the replicative cycle of influenza A virus (IAV) via forming the ribonucleoprotein complex together with PB2, PB1, and PA proteins. As its high conservation, NP ... 5184 items, 20/Page, Page[24/260][|<<] [|<] [21] [22] [23] [24] [25] [26] [27] [28] [29] [30] [>|] [>>|] |
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