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2024-5-4 7:12:50
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YAN Ju-ying, etc.,al. Pathogenicity and Molecular Characterization of the H5N1 Influenza Virus Isolated from the First Human Case in Zhejiang Province. Virologica Sinica.  Abstract  
submitted by kickingbird at Oct, 28, 2006 from Virologica Sinica
In order to confirm the etiology of the first suspected human case of the highly-pathogenic avian influenza virus and to perform the pathogenicity studies, a tracheal aspirate specimen was tested by RT-PCR, ...

Z. Kou, F. M. Lei, J. Yu, Z. J. Fan, Z. H. Yin, C.. New Genotype of Avian Influenza H5N1 Viruses Isolated from Tree Sparrows in China. J. Virol. 2005 79: 15460-15466.  Abstract  
submitted by kickingbird at Oct, 26, 2006 from J. Virol. 2005 79: 15460-15466 (via http://jvi.asm.org/cgi/content/full/79/24/15460?maxtoshow=&H)
The 2004 outbreaks of highly pathogenic avian influenza H5N1 disease in China led to a great poultry loss and society attention. A survey of avian influenza viruses was conducted on tree sparrows (Passer ...

Brown JD, Stallknecht DE, Beck JR, Suarez DL, Sway. Susceptibility of North American Ducks and Gulls to H5N1 Highly Pathogenic Avian Influenza Viruses. Emerg Infect Dis. 2006 Nov publication.  Abstract  
submitted by kickingbird at Oct, 26, 2006 from Emerg Infect Dis. 2006 Nov publication (via http://www.cdc.gov/ncidod/EID/vol12no11/06-0652.htm)
Since 2002, H5N1 highly pathogenic avian influenza (HPAI) viruses have been associated with deaths in numerous wild avian species throughout Eurasia. We assessed the clinical response and extent and duration ...

Desheva JA, Lu XH, Rekstin AR, Rudenko LG, Swayne. Characterization of an influenza A H5N2 reassortant as a candidate for live-attenuated and inactivated vaccines against highly pathogenic H5N1 viruses with pandemic potential. Vaccine. 2006 Jun 28.  Abstract  
submitted by kickingbird at Oct, 24, 2006 from Vaccine. 2006 Jun 28 (via http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&d)
We generated a high-growth 7:1 reassortant (Len17/H5) that contained the hemagglutinin (HA) gene from non-pathogenic A/Duck/Potsdam/1402-6/86 (H5N2) virus and other genes from the cold-adapted (ca) attenuated ...

Guo Z, Chen LM, Zeng H, Gomez JA, Plowden J, Fujit. NS1 Protein of Influenza A Virus Inhibits the Function of Intracytoplasmic Pathogen Sensor, RIG-I. Am J Respir Cell Mol Biol. 2006 Oct 19.  Abstract  
submitted by kickingbird at Oct, 24, 2006 from Am J Respir Cell Mol Biol. 2006 Oct 19 (via http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&d)
Retinoic acid-inducible gene I (RIG-I) has recently been identified as one of the key intracellular sensors of virus infection. RIG-I binds to cytosolic double-stranded RNA and initiates a signaling cascade ...

Sawada T, Hashimoto T, Nakano H, Suzuki T, Ishida. Why does avian influenza A virus hemagglutinin bind to avian receptor stronger than to human receptor? Ab initio fragment molecular orbital studies. Biochem Biophys Res Commun. 2006 Oct 12.  Abstract  
submitted by kickingbird at Oct, 24, 2006 from Biochem Biophys Res Commun. 2006 Oct 12 (via http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&d)
Influenza A viruses attach to alpha-sialosides on the target cell surface by their hemagglutinins, which strictly recognize the difference in sialic acid-galactose linkage. Why does avian virus H3 subtype ...

Wu G, Yan S. Fate of influenza A virus proteins. Medline.  Abstract  
submitted by DreamSciTech at Oct, 24, 2006 from Medline (via http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=pubmed&cmd=)
In this review we summarize the current state, history, future, mutation tendency and species susceptibility of influenza A virus proteins based on our probabilistic analyses on amino acid pairs, and compare ...

Glass RJ, Glass LM, Beyeler WE, Min HJ.. Targeted Social Distancing Design for Pandemic Influenza. Emerg Infect Dis 2006 Nov.  Abstract  
submitted by kickingbird at Oct, 24, 2006 from Emerg Infect Dis 2006 Nov (via http://www.cdc.gov/ncidod/EID/vol12no11/06-0255.htm)
Targeted social distancing to mitigate pandemic influenza can be designed through simulation of influenza's spread within local community social contact networks. We demonstrate this design for a stylized ...

Kong W, Hood C, Yang A, et al.. Protective immunity to lethal challenge of the 1918 pandemic influenza virus by vaccination. Proc Nat Acad Sci 2006;103(43):15987-91.  Abstract  
submitted by kickingbird at Oct, 22, 2006 from Proc Nat Acad Sci 2006;103(43):15987-91 (via http://www.pnas.org/cgi/reprint/0607564103v1)
The remarkable infectivity and virulence of the 1918 influenza virus resulted in an unprecedented pandemic, raising the question of whether it is possible to develop protective immunity to this virus and ...

BAO Hong-mei, etc.,al. Development of a one-step RT-PCR assay for detection of A subtype avian influenza virus. Veterinary Science in China.  Abstract  
submitted by kickingbird at Oct, 15, 2006 from Veterinary Science in China
A one-step RT-PCR assay was developed to detect avian influenza virus(AIV).A pair of specific oligonucleotide primers was designed for the detection of AIV according to M gene sequences.Sensitivity for ...

Watanabe K, Fuse T, Asano I, Tsukahara F, Maru Y,. Identification of Hsc70 as an influenza virus matrix protein (M1) binding factor involved in the virus life cycle. FEBS Lett. 2006 Sep 27.  Abstract  
submitted by kickingbird at Oct, 10, 2006 from FEBS Lett. 2006 Sep 27 (via http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&d)
Influenza virus matrix protein 1 (M1) has been shown to play a crucial role in the virus replication, assembly and budding. We identified heat shock cognate protein 70 (Hsc70) as a M1 binding protein by ...

Guang Wu, Shaomin Yan. Searching of main cause leading to severe influenza A virus mutations and consequently to influenza pandemics/epidemics. Am J Infect Dis.  Full Text  
submitted by DreamSciTech at Oct, 10, 2006 from Am J Infect Dis (via www.scientificworld.net/fulltext/ajid/ajid12116-123.pdf)
Abstract: The unpredictable mutations in the proteins from influenza A virus lead to the greatdifficulty in prevention of possible outbreak of bird flu and pandemic/epidemic of influenza. Thisunpredictability ...

Tellier R.. Review of Aerosol Transmission of Influenza A Virus. Emerg Infect Dis. 2006 Nov edition.  Full Text  
submitted by kickingbird at Oct, 9, 2006 from Emerg Infect Dis. 2006 Nov edition (via http://www.cdc.gov/ncidod/EID/vol12no11/06-0426.htm)
Concerns about the likely occurrence of an influenza pandemic in the near future are increasing. The highly pathogenic strains of influenza A (H5N1) virus circulating in Asia, Europe, and Africa have become ...

Wu G, Yan SM.. Mutation trend of hemagglutinin of influenza A virus: a review from a computational mutation viewpoint. Acta Pharmacol Sin. 2006 May;27(5):513-26.  Abstract  
submitted by kickingbird at Sep, 30, 2006 from Acta Pharmacol Sin. 2006 May;27(5):513-26 (via http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=pubmed&cmd=)
Since 1999 we have developed two computational mutation approaches to analyze the protein primary structure whose methodology and implications were reviewed in 2002. Our first approach is the calculation ...

Chen G-W, Chang S-C, Mok C-K, Lo Y-L, Kung Y-N, Hu. Genomic Signatures of Human versus Avian Influenza A Viruses. Emerg Infect Dis. 2006 Sep.  Abstract  
submitted by kickingbird at Sep, 30, 2006 from Emerg Infect Dis. 2006 Sep (via http://www.cdc.gov/NCIDOD/eid/vol12no09/06-0276.htm)
Position-specific entropy profiles created from scanning 306 human and 95 avian influenza A viral genomes showed that 228 of 4,591 amino acid residues yielded significant differences between these 2 viruses. ...

Wang S, Taaffe J, Parker C, Solorzano A, Cao H, Ga. The Hemagglutinin (HA) Proteins from H1 and H3 Serotypes of Influenza A Viruses Require Different Antigen Designs for the Induction of Optimal Protective Antibody Responses as Studied by Codon Optimiz. J Virol. 2006 Sep 20; [Epub ahead of print].  Abstract  
submitted by kickingbird at Sep, 28, 2006 from J Virol. 2006 Sep 20; [Epub ahead of print] (via http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&d)
Effective antibody responses provide crucial immunity against influenza (Flu) virus infection. The hemagglutinin (HA) protein is the major target of protective antibody responses induced by viral infection ...

Lipatov AS, Hoffmann E, Salomon R, Yen HL, Webster. Cross-Protectiveness and Immunogenicity of Influenza A/Duck/Singapore/3/97(H5) Vaccines against Infection with A/Vietnam/1203/04(H5N1) Virus in Ferrets. J Infect Dis. 2006 Oct 15;194(8):1040-3. Epub 2006.  Abstract  
submitted by kickingbird at Sep, 28, 2006 from J Infect Dis. 2006 Oct 15;194(8):1040-3. Epub 2006 (via http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&d)
Ferrets were immunized with two 7- mu g doses of hemagglutinin from inactivated whole-virus vaccines containing the hemagglutinin gene of A/Duck/Singapore/3/97(H5N3) then inoculated with a lethal dose ...

John C. Kash et al.. Genomic analysis of increased host immune and cell death responses induced by 1918 influenza virus. Nature advance online publication 27 September 200.  Abstract  
submitted by kickingbird at Sep, 28, 2006 from Nature advance online publication 27 September 200 (via http://www.nature.com/nature/journal/vaop/ncurrent/abs/natur)
The influenza pandemic of 1918–19 was responsible for about 50 million deaths worldwide1. Modern histopathological analysis of autopsy samples from human influenza cases from 1918 revealed significant ...

Wu G, Yan S. Determination of mutation trend in hemagglutinins by means of translation probability between RNA codons and mutated amino acids. Protein Pept Lett. 2006;13(6):601-9.  Abstract  
submitted by kickingbird at Sep, 26, 2006 from Protein Pept Lett. 2006;13(6):601-9 (via http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=pubmed&cmd=)
In this study, we used the 183 translation probabilities between RNA codons and mutated amino acids to construct the theoretical distributions of mutated amino acids in hemagglutinins of influenza A virus. ...

Rappole JH, Hubálek Z. Birds and Influenza H5N1 Virus Movement to and within North America. Emerg Infect Dis. 2006 Oct.  Abstract  
submitted by kickingbird at Sep, 23, 2006 from Emerg Infect Dis. 2006 Oct (via http://www.cdc.gov/ncidod/EID/vol12no10/05-1577.htm?s_cid=ei)
Highly pathogenic avian influenza (HPAI) H5N1 expanded considerably during 2005 and early 2006 in both avian host species and geographic distribution. Domestic waterfowl and migratory birds are reservoirs, ...

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