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2024-11-23 8:25:02
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Meroz D, Yoon SW, Ducatez MF, Fabrizio TP, Webby R. Putative amino acid determinants of the emergence of the 2009 influenza A (H1N1) virus in the human population. Proc Natl Acad Sci U S A. 2011 Aug 1..  Abstract  
submitted by kickingbird at Aug, 12, 2011 from Proc Natl Acad Sci U S A. 2011 Aug 1. (via http://www.ncbi.nlm.nih.gov/pubmed/21808039)
The emergence of the unique H1N1 influenza A virus in 2009 resulted in a pandemic that has spread to over 200 countries. The constellation of molecular factors leading to the emergence of this strain is ...

Lalle E, Bordi L, Meschi S, Selleri M, Valli MB, P. Comparison of two real-time RT-PCR-based systems for the detection and typing of the pandemic influenza A virus, 2009. J Virol Methods. 2011 Jul 21.  Abstract  
submitted by kickingbird at Aug, 12, 2011 from J Virol Methods. 2011 Jul 21 (via http://www.ncbi.nlm.nih.gov/pubmed/21807027)
During the 2009 pandemic the Virology Laboratory of L. Spallanzani, Rome, Italy, adopted a real-time RT-PCR developed by the Centers for Disease Control and Prevention (CDC), Atlanta, Georgia to diagnose ...

Zhirnov OP, Klenk HD, Wright PF.. Aprotinin and similar protease inhibitors as drugs against influenza. Antiviral Res. 2011 Jul 23.  Abstract  
submitted by kickingbird at Aug, 12, 2011 from Antiviral Res. 2011 Jul 23 (via http://www.ncbi.nlm.nih.gov/pubmed/21802447)
Efforts to develop new antiviral chemotherapeutic approaches are focusing on compounds that target either influenza virus replication itself or host factor(s) that are critical to influenza replication. ...

Fiebig L, Soyka J, Buda S, Buchholz U, Dehnert M,. Avian influenza A(H5N1) in humans: new insights from a line list of World Health Organization confirmed cases, September 2006 to August 2010. Eurosurveillance, Volume 16, Issue 32, 11 August 2.  Abstract  
submitted by kickingbird at Aug, 12, 2011 from Eurosurveillance, Volume 16, Issue 32, 11 August 2 (via http://www.eurosurveillance.org/ViewArticle.aspx?ArticleId=1)
Introduction Avian influenza (AI) has received public attention since 1997 when human infections and thereof six fatal cases due to the highly pathogenic avian influenza A(H5N1) virus strain were ...

Kimble JB, Sorrell E, Shao H, Martin PL, Perez DR.. Compatibility of H9N2 avian influenza surface genes and 2009 pandemic H1N1 internal genes for transmission in the ferret model. Proc Natl Acad Sci U S A. 2011 Jul 5.  Abstract  
submitted by kickingbird at Jul, 13, 2011 from Proc Natl Acad Sci U S A. 2011 Jul 5 (via http://www.ncbi.nlm.nih.gov/pubmed/21730147)
In 2009, a novel H1N1 influenza (pH1N1) virus caused the first influenza pandemic in 40 y. The virus was identified as a triple reassortant between avian, swine, and human influenza viruses, highlighting ...

Mok CK, Yen HL, Yu MY, Yuen KM, Sia SF, Chan MC, Q. Amino acid residues 253 and 591 of the PB2 protein of avian influenza virus A H9N2 contributes to mammalian pathogenesis. J Virol. 2011 Jul 6.  Abstract  
submitted by kickingbird at Jul, 13, 2011 from J Virol. 2011 Jul 6 (via http://www.ncbi.nlm.nih.gov/pubmed/21734052)
We investigated the tropism, host responses and virulence of two variants of A/Quail/Hong Kong/G1/1997 (H9N2) (H9N2/G1) with D253N and Q591K in the PB2 protein in primary human macrophages and bronchial ...

Sugaya N, Shinjoh M, Mitamura K, Takahashi T.. Very low pandemic influenza A (H1N1) 2009 mortality associated with early neuraminidase inhibitor treatment in Japan: Analysis of 1000 hospitalized children. J Infect. 2011 Jun 22.  Abstract  
submitted by kickingbird at Jul, 13, 2011 from J Infect. 2011 Jun 22 (via http://www.ncbi.nlm.nih.gov/pubmed/21722665)
OBJECTIVE: There were many cases of pandemic influenza A (H1N1) 2009 (H1N1/09) in Japan during the 2009-2010 epidemic. They accounted for 16% of the total population (20.7 million/128 million), and 59% ...

Knibbs LD, Morawska L, Bell SC.. The risk of airborne influenza transmission in passenger cars. Epidemiol Infect. 2011 May 9:1-5.  Abstract  
submitted by kickingbird at Jul, 13, 2011 from Epidemiol Infect. 2011 May 9:1-5 (via http://www.ncbi.nlm.nih.gov/pubmed/21733264)
SUMMARYTravel in passenger cars is a ubiquitous aspect of the daily activities of many people. During the 2009 influenza A(H1N1) pandemic a case of probable transmission during car travel was reported ...

Song DS, An DJ, Moon HJ, Yeom MJ, etc.,al. Interspecies transmission of the canine influenza H3N2 virus to domestic cats in South Korea, 2010. J Gen Virol. 2011 Jun 29..  Abstract  
submitted by kickingbird at Jul, 3, 2011 from J Gen Virol. 2011 Jun 29. (via http://www.ncbi.nlm.nih.gov:80/pubmed/21715595)
In the last 4 years, incidences of endemic or epidemic respiratory diseases associated with canine influenza H3N2 virus in Asian dogs have been reported in countries such as South Korea and China. Canine ...

Zimmermann P, M?nz B, Haller O, Schwemmle M, Kochs. The viral nucleoprotein determines Mx sensitivity of influenza A viruses.. J Virol. 2011 Jun 15.  Abstract  
submitted by kickingbird at Jun, 27, 2011 from J Virol. 2011 Jun 15 (via http://www.ncbi.nlm.nih.gov/pubmed/21680506)
Host restriction factors play a crucial role in preventing trans-species transmission of viral pathogens. In mammals, the interferon-induced Mx GTPases are powerful antiviral proteins restricting orthomyxoviruses. ...

Octaviani CP, Goto H, Kawaoka Y.. Reassortment between seasonal H1N1 and pandemic (H1N1) 2009 influenza viruses is restricted by limited compatibility among polymerase subunits. J Virol. 2011 Jun 15.  Abstract  
submitted by kickingbird at Jun, 27, 2011 from J Virol. 2011 Jun 15 (via http://www.ncbi.nlm.nih.gov/pubmed/21680507)
Reassortment is important for influenza virus evolution and the generation of novel viruses with pandemic potential; however, the factors influencing reassortment are still poorly understood. Here, using ...

NFON CK, Berhane Y, Hisanaga T, Zhang S, et al. Characterization of H1N1 swine influenza viruses circulating in Canadian pigs in 2009. J Virol. 2011 Jun 22.  Abstract  
submitted by kickingbird at Jun, 27, 2011 from J Virol. 2011 Jun 22 (via http://www.ncbi.nlm.nih.gov/pubmed/21697484)
The 2009 pandemic H1N1 (pH1N1), of apparent swine origin, may have evolved in pigs unnoticed because of insufficient surveillance. Consequently, the need for surveillance of influenza viruses circulating ...

Trevino C, Bihon S, Pinsky BA.. A Synonymous Change in the Influenza A Neuraminidase Gene Interferes with PCR-based Subtyping and Oseltamivir Resistance Mutation Detection. J Clin Microbiol. 2011 Jun 22..  Abstract  
submitted by kickingbird at Jun, 27, 2011 from J Clin Microbiol. 2011 Jun 22. (via http://www.ncbi.nlm.nih.gov/pubmed/21697334)
Rapid detection of the emergence of oseltamivir-resistant influenza A is critically important for both public health surveillance and the selection of appropriate antiviral therapy.…

FRENSING T, Seitz C, Heynisch B, Patzina C, et al.. Efficient influenza B virus propagation due to deficient interferon-induced antiviral activity in MDCK cells. Vaccine. 2011 Jun 4..  Abstract  
submitted by kickingbird at Jun, 14, 2011 from Vaccine. 2011 Jun 4. (via http://www.ncbi.nlm.nih.gov/pubmed/21651940)
Influenza B virus infections are mainly restricted to humans, which is partially caused by the inability of influenza B virus NS1 protein to counteract the innate immune response of other species. However, ...

WEI HJ, Chang W, Lin SC, Liu WC, et al. Fabrication of influenza virus-like particles using M2 fusion proteins for imaging single viruses and designing vaccines. Vaccine. 2011 Jun 4.  Abstract  
submitted by kickingbird at Jun, 14, 2011 from Vaccine. 2011 Jun 4 (via http://www.ncbi.nlm.nih.gov/pubmed/21651946)
Influenza virus-like particles (VLPs) are noninfectious and the assembly of influenza VLPs depends on the interactions of M1 proteins and/or other viral surface proteins, such as HA, NA, and M2, with the ...

TSAI SM, Chiang YC, Chin LT, Liu HJ, et al.. Novel post-translational modifications of the hemagglutinin and neuraminidase proteins of avian influenza virus expressed by Kluyveromyces lactis. J Virol Methods. 2011 May 27.  Abstract  
submitted by kickingbird at Jun, 14, 2011 from J Virol Methods. 2011 May 27 (via http://www.ncbi.nlm.nih.gov/pubmed/21640140)
Avian influenza virus (AIV) is an enveloped virus with segmented RNA that belongs to the Orthomyxoviridae. Recently, avian influenza virus isolates have not only posed a significant threat to the poultry ...

WANG M, Qi J, Liu Y, Vavricka CJ, et al. Influenza A virus neuraminidase N5 has an extended 150-cavity. J Virol. 2011 Jun 8..  Abstract  
submitted by kickingbird at Jun, 14, 2011 from J Virol. 2011 Jun 8. (via http://www.ncbi.nlm.nih.gov/pubmed/21653672)
There are 9 serotypes of neuraminidase (NA) from influenza A virus (N1-N9) which are classified into two groups based on primary sequences (group 1 and 2). The structural hallmark of the two groups is ...

Govorkova EA, Marathe BM, Prevost A, Rehg JE, Webs. Assessment of the efficacy of the neuraminidase inhibitor oseltamivir against 2009 pandemic H1N1 influenza virus in ferrets. Antiviral Res. 2011 May 27.  Abstract  
submitted by kickingbird at Jun, 8, 2011 from Antiviral Res. 2011 May 27 (via http://www.ncbi.nlm.nih.gov/pubmed/21635924)
Pandemic 2009 influenza A (H1N1) virus (H1N1pdm) is different from contemporary seasonal human viruses in that it can cause infection deep in the lungs of critical care patients. Here we establish a mammalian ...

SPESOCK A, Malur M, Hossain MJ, Chen LM, et al. The virulence of 1997 H5N1 influenza viruses in the mouse model is increased by correcting a defect in their NS1 proteins. J Virol. 2011 May 18.  Abstract  
submitted by kickingbird at May, 28, 2011 from J Virol. 2011 May 18 (via http://www.ncbi.nlm.nih.gov/pubmed/21593152)
The NS1 protein of human influenza A viruses binds the 30-kDa subunit of the cleavage and polyadenylation specificity factor (CPSF30), a protein required for 3' end processing of cellular pre-mRNAs, thereby ...

SMITH JH, Nagy T, Driskell E, Brooks P, etc al. Comparative Pathology in Ferrets Infected with H1N1 Influenza A Viruses Isolated from Different Hosts. J Virol. 2011 May 18..  Abstract  
submitted by kickingbird at May, 28, 2011 from J Virol. 2011 May 18. (via http://www.ncbi.nlm.nih.gov/pubmed/21593156)
Virus replication and pulmonary disease pathogenesis in ferrets following intranasal infection with a pandemic influenza strain (A/California/4/09; CA09), a human seasonal influenza H1N1 isolate (A/New ...

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