Raviv Y, Blumenthal R, Tompkins SM, Humberd J, Hog. Hydrophobic Inactivation of Influenza Viruses confers Preservation of Viral Structure with Enhanced Immunogenicity. J Virol. 2008 Feb 27. Abstract
submitted by kickingbird at Mar, 19, 2008 from J Virol. 2008 Feb 27 (via http://www.ncbi.nlm.nih.gov/pubmed/18305038?dopt=Abstract)
The use of inactivated influenza virus for the development of vaccines with broad heterosubtypic protection requires selective inactivation techniques that eliminate viral infectivity while preserving ... Gabriel G, Herwig A, Klenk HD.. Interaction of Polymerase Subunit PB2 and NP with Importin alpha1 Is a Determinant of Host Range of Influenza A Virus. PLoS Pathog. 2008 Feb 1;4(2):e11. Full Text
submitted by kickingbird at Mar, 19, 2008 from PLoS Pathog. 2008 Feb 1;4(2):e11 (via http://www.plospathogens.org/article/info:doi/10.1371/journa)
We have previously reported that mutations in the polymerase proteins PB1, PB2, PA, and the nucleocapsid protein NP resulting in enhanced transcription and replication activities in mammalian cells are ... Srinivasan A, Viswanathan K, Raman R, Chandrasekar. Quantitative biochemical rationale for differences in transmissibility of 1918 pandemic influenza A viruses. Proc Natl Acad Sci U S A. 2008 Feb 26;105(8):2800-. Full Text
submitted by kickingbird at Mar, 19, 2008 from Proc Natl Acad Sci U S A. 2008 Feb 26;105(8):2800- (via http://www.pnas.org/cgi/content/full/105/8/2800)
The human adaptation of influenza A viruses is critically governed by the binding specificity of the viral surface hemagglutinin (HA) to long (chain length) alpha2-6 sialylated glycan (alpha2-6) receptors ... Jackson D, Hossain MJ, Hickman D, Perez DR, Lamb R. A new influenza virus virulence determinant: The NS1 protein four C-terminal residues modulate pathogenicity. Proc Natl Acad Sci U S A. 2008 Mar 11. Full Text
submitted by kickingbird at Mar, 18, 2008 from Proc Natl Acad Sci U S A. 2008 Mar 11 (via http://www.pnas.org/cgi/reprint/0800482105v1)
The virulence of influenza virus is a multigenic trait. One determinant of virulence is the multifunctional NS1 protein that functions in several ways to defeat the cellular innate immune response. Recent ... Vanlaere I, Vanderrijst A, Guénet JL, De Filette M. Mx1 causes resistance against influenza A viruses in the Mus spretus-derived inbred mouse strain SPRET/Ei. Cytokine. 2008 Mar 9. Abstract
submitted by kickingbird at Mar, 18, 2008 from Cytokine. 2008 Mar 9 (via http://www.ncbi.nlm.nih.gov/pubmed/18334301?ordinalpos=22&it)
Inbred SPRET/Ei mice, derived from Mus spretus, were found to be extremely resistant to infection with a mouse adapted influenza A virus. The resistance was strongly linked to distal chromosome 16, where ... Busch MG, Bateman AC, Landolt GA, Karasin AI, Broc. Identification of amino acids in the HA of H3 influenza viruses that determine infectivity levels in primary swine respiratory epithelial cells. Virus Res. 2008 Mar 7. Abstract
submitted by kickingbird at Mar, 18, 2008 from Virus Res. 2008 Mar 7 (via http://www.ncbi.nlm.nih.gov/pubmed/18329747?ordinalpos=29&it)
In the late 1990s, triple reassortant H3N2 influenza A viruses emerged and spread widely within the swine population of the United States. We have shown previously that an isolate representative of this ... Mancini DA, Alves RC, Mendon?a RM, Bellei NJ, Carr. Influenza virus and proteolytic bacteria co-infection in respiratory tract from individuals presenting respiratory manifestations. Rev Inst Med Trop Sao Paulo. 2008 Feb;50(1):41-46. Abstract
submitted by kickingbird at Mar, 18, 2008 from Rev Inst Med Trop Sao Paulo. 2008 Feb;50(1):41-46 (via http://www.ncbi.nlm.nih.gov/pubmed/18327486?ordinalpos=36&it)
A role for proteolytic bacteria in the exacerbation of influenza virus has been shown in natural hosts such as pigs and humans. Four hundred seven samples were collected from the respiratory tract of individuals ... Li WC, Shih SR, Huang YC, Chen GW, Chang SC, Hsiao. Clinical and genetic characterization of severe influenza B-associated diseases during an outbreak in Taiwan. J Clin Virol. 2008 Mar 4. Abstract
submitted by kickingbird at Mar, 18, 2008 from J Clin Virol. 2008 Mar 4 (via http://www.ncbi.nlm.nih.gov/pubmed/18325832?ordinalpos=39&it)
BACKGROUND: Mismatches between circulating and vaccine strains of influenza virus had been observed in Taiwan. A comprehensive clinical and genetic analysis of influenza B viruses-associated important ... Long JX, Peng DX, Liu YL, Wu YT, Liu XF.. Virulence of H5N1 avian influenza virus enhanced by a 15-nucleotide deletion in the viral nonstructural gene. Virus Genes. 2008 Mar 4. Abstract
submitted by kickingbird at Mar, 9, 2008 from Virus Genes. 2008 Mar 4 (via http://www.ncbi.nlm.nih.gov/pubmed/18317917?ordinalpos=46&it)
More and more H5N1 subtype avian influenza viruses possessing a 15-nucleotide (15-nt) deletion in the viral nonstructural protein (NS) gene from position 263 to 277 have emerged since 2000. In order to ... Nandi T.. Proposed lead molecules against Hemagglutinin of avian influenza virus (H5N1).. Bioinformation. 2008 Jan 27;2(6):240-4. Abstract
submitted by kickingbird at Mar, 9, 2008 from Bioinformation. 2008 Jan 27;2(6):240-4 (via http://www.ncbi.nlm.nih.gov/pubmed/18317572?ordinalpos=47&it)
Human infection with avian influenza H5N1 is an emerging infectious disease characterized by respiratory symptoms and a high fatality rate. Hemagglutinin and neuraminidase are the two surface proteins ... Yamanaka T, Tsujimura K, Kondo T, Matsumura T.. Evaluation of antigen detection kits for diagnosis of equine influenza. J Vet Med Sci. 2008 Feb;70(2):189-92.. Abstract
submitted by kickingbird at Mar, 9, 2008 from J Vet Med Sci. 2008 Feb;70(2):189-92. (via http://www.ncbi.nlm.nih.gov/pubmed/18319581?ordinalpos=37&it)
In this study, we evaluated whether five rapid antigen detection kits for human influenza could be used for the diagnosis of equine influenza (EI). Limiting dilution analyses showed that Directigen Flu ... Patterson-Kane JC, Carrick JB, Axon JE, Wilkie I,. The pathology of bronchointerstitial pneumonia in young foals associated with the first outbreak of equine influenza in Australia. Equine Vet J. 2008 Feb 27. Abstract
submitted by kickingbird at Mar, 9, 2008 from Equine Vet J. 2008 Feb 27 (via http://www.ncbi.nlm.nih.gov/pubmed/18321807?ordinalpos=27&it)
Reasons for performing study: The first outbreak of equine influenza virus (EIV) infection was confirmed in Australia in 2007. Some EIV-positive young foals died with bronchointerstitial pneumonia, an ... Kryazhimskiy S, Bazykin GA, Dushoff J.. Natural selection for nucleotide usage at synonymous and non-synonymous sites in the influenza A genes. J Virol. 2008 Mar 5. Abstract
submitted by kickingbird at Mar, 9, 2008 from J Virol. 2008 Mar 5 (via http://www.ncbi.nlm.nih.gov/pubmed/18321967?ordinalpos=25&it)
Influenza A is one of the best studied viruses and a model organism for the study of molecular evolution; in particular, much research has focused on detecting natural selection on influenza proteins. ... Xing Z, Cardona C, Dao P, Crossley B, Hietala S, B. Realtime RT-PCR Assay Unable to Detect H7 Subtype Avian Influenza Viruses Isolated from Wild Birds. J Clin Microbiol. 2008 Mar 5. Abstract
submitted by kickingbird at Mar, 9, 2008 from J Clin Microbiol. 2008 Mar 5 (via http://www.ncbi.nlm.nih.gov/pubmed/18322070?ordinalpos=22&it)
We report a failure of the current real-time RT-PCR H7 subtyping protocol, used in national avian influenza surveillance programs. Significant substitutions in primer and probe target sequences were identified, ... Huang IC, Li W, Sui J, Marasco W, Choe H, Farzan M. Influenza A virus neuraminidase limits viral superinfection.. J Virol. 2008 Mar 5. Abstract
submitted by kickingbird at Mar, 9, 2008 from J Virol. 2008 Mar 5 (via http://www.ncbi.nlm.nih.gov/pubmed/18321971?ordinalpos=24&it)
Enveloped viruses use multiple mechanisms to inhibit infection of a target cell by more than one virion. These mechanisms may be of particular importance for the evolution of segmented viruses, because ... Bragstad K, Nielsen LP, Fomsgaard A.. The evolution of human influenza A viruses from 1999 to 2006 - a complete genome study. Virol J. 2008 Mar 7;5(1):40. Abstract
submitted by kickingbird at Mar, 9, 2008 from Virol J. 2008 Mar 7;5(1):40 (via http://www.ncbi.nlm.nih.gov/pubmed/18325125?ordinalpos=13&it)
ABSTRACT: BACKGROUND: Knowledge about the complete genome constellation of seasonal influenza A viruses from different countries is valuable for the monitoring and understanding of the evolution and migration ... Daly JM, Blunden AS, Macrae S, Miller J, Bowman SJ. Transmission of equine influenza virus to english foxhounds. Emerg Infect Dis. 2008 Mar;14(3):461-4. Abstract
submitted by kickingbird at Mar, 9, 2008 from Emerg Infect Dis. 2008 Mar;14(3):461-4 (via http://www.ncbi.nlm.nih.gov/pubmed/18325262?ordinalpos=11&it)
We retrospectively demonstrated that an outbreak of severe respiratory disease in a pack of English foxhounds in the United Kingdom in September 2002 was caused by an equine influenza A virus (H3N8). We ... Hinjoy S, Puthavathana P, Laosiritaworn Y, Limpaka. Low Frequency of Infection with Avian Influenza Virus (H5N1) among Poultry Farmers, Thailand, 2004. Emerg Infect Dis. 2008 Mar;14(3):499-501. Abstract
submitted by kickingbird at Mar, 9, 2008 from Emerg Infect Dis. 2008 Mar;14(3):499-501 (via http://www.ncbi.nlm.nih.gov/pubmed/18325273?ordinalpos=7&ito)
In Thai provinces where avian influenza outbreaks in poultry had been confirmed in the preceding 6 months, serum from 322 poultry farmers was tested for antibodies to avian influenza virus subtype H5N1 ... Altiok E, Taylan F, Yenen OS, Demirkeser G, Bozaci. Mutations in Influenza A Virus (H5N1) and Possible Limited Spread, Turkey, 2006. Emerg Infect Dis. 2008 Mar;14(3):491-2. Abstract
submitted by kickingbird at Mar, 9, 2008 from Emerg Infect Dis. 2008 Mar;14(3):491-2 (via http://www.ncbi.nlm.nih.gov/pubmed/18325270?ordinalpos=8&ito)
We report mutations in influenza A virus (H5N1) strains associated with 2 outbreaks in Turkey. Four novel amino acid changes (Q447L, N556K, and R46K in RNA polymerase and S133A in hemagglutinin) were detected ... Lee YJ, Choi YK, Kim YJ, Song MS, Jeong OM, Lee EK. Highly Pathogenic Avian Influenza Virus (H5N1) in Domestic Poultry and Relationship with Migratory Birds, South Korea. Emerg Infect Dis. 2008 Mar;14(3):487-490. Abstract
submitted by kickingbird at Mar, 9, 2008 from Emerg Infect Dis. 2008 Mar;14(3):487-490 (via http://www.ncbi.nlm.nih.gov/pubmed/18325269?ordinalpos=9&ito)
During the 2006-2007 winter season in South Korea, several outbreaks of highly pathogenic avian influenza virus (H5N1) were confirmed among domestic poultry and in migratory bird habitats. Phylogenetic ... 5170 items, 20/Page, Page[219/259][|<<] [|<] [211] [212] [213] [214] [215] [216] [217] [218] [219] [220] [>|] [>>|] |
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