Li J, Musarat Ishaq, Prudence M, Hu T, Liu Q, Guo. Single mutation at the amino acid position 627 of PB2 that leads to increased virulence of an H5N1 avian influenza virus during adaptation in mice can be compensated by multiple mutations at other sit. Virus Res. 2009 Apr 22. Abstract
submitted by kickingbird at Apr, 28, 2009 from Virus Res. 2009 Apr 22 (via http://www.ncbi.nlm.nih.gov/pubmed/19393699?ordinalpos=13&it)
To understand the adaptation of H5N1 influenza viruses to mammals, a non-pathogenic influenza H5N1 virus (HN021) in mice was passaged for 15 times in mammalian host. Animal experiment results indicated ... Tu J, Zhou H, Jiang T, Li C, Zhang A, Guo X, Zou W. Isolation and molecular characterization of equine H3N8 influenza viruses from pigs in China. Arch Virol. 2009 Apr 26.. Abstract
submitted by kickingbird at Apr, 28, 2009 from Arch Virol. 2009 Apr 26. (via http://www.ncbi.nlm.nih.gov/pubmed/19396578?ordinalpos=1&ito)
During 2004-2006 swine influenza virus surveillance, two strains of H3N8 influenza viruses were isolated from pigs in central China. Sequence and phylogenetic analyses of eight gene segments revealed that ... Bastien N, Bowness D, Burton L, Bontovics E, Winte. Parotitis in a Child Infected with Triple Reassortant Influenza A, Canada, 2007. J Clin Microbiol. 2009 Apr 1.. Abstract
submitted by kickingbird at Apr, 5, 2009 from J Clin Microbiol. 2009 Apr 1. (via http://www.ncbi.nlm.nih.gov/pubmed/19339469)
Swine H3N2 influenza virus designated A/Ontario/1252/07 was isolated from a child with parotitis. Diagnosis was confirmed by viral isolation and serological assays. A/Ontario/1252/07 was related to H3N2 ... Sui B, Bamba D, Weng K, Ung H, Chang S, Van Dyke J. The use of Random Homozygous Gene Perturbation to identify novel host-oriented targets for influenza. Virology. 2009 Mar 26. Abstract
submitted by kickingbird at Apr, 5, 2009 from Virology. 2009 Mar 26 (via http://www.ncbi.nlm.nih.gov/pubmed/19327807)
Conventional approaches for therapeutic targeting of viral pathogens have consistently faced obstacles arising from the development of resistant strains and a lack of broad-spectrum application. Influenza ... Lesnoff M, Peyre M, Duarte PC, Renard JF, Mariner. A simple model for simulating immunity rate dynamics in a tropical free-range poultry population after avian influenza vaccination. Epidemiol Infect. 2009 Mar 30:1-9.. Abstract
submitted by kickingbird at Apr, 5, 2009 from Epidemiol Infect. 2009 Mar 30:1-9. (via http://www.ncbi.nlm.nih.gov/pubmed/19327199)
SUMMARYIn developing countries, vaccination against highly pathogenic avian influenza subtype H5N1 (HPAI) in free-range poultry flocks is usually implemented as periodic campaigns and newborn chicks are ... Tamura D, Mitamura K, Yamazaki M, Fujino M, Nirasa. Oseltamivir-Resistant Influenza A Viruses Circulating in Japan. J Clin Microbiol. 2009 Mar 4. Abstract
submitted by kickingbird at Mar, 8, 2009 from J Clin Microbiol. 2009 Mar 4 (via http://www.ncbi.nlm.nih.gov/pubmed/19261802)
Surveillance studies of influenza viruses circulating in Europe and other countries in 2007-2008 have revealed rates of resistance to oseltamivir of up to 67% among H1N1 viruses. Here, we examined 202 ... Crouch E, Hartshorn K, Horlacher T, McDonald B. Recognition of Mannosylated Ligands and Influenza A Virus by Human SP-D: Contributions of an Extended Site and Residue 343. Biochemistry. 2009 Feb 27. Abstract
submitted by kickingbird at Mar, 8, 2009 from Biochemistry. 2009 Feb 27 (via http://www.ncbi.nlm.nih.gov/pubmed/19249874)
Surfactant protein D (SP-D) plays important roles in antiviral host defense. Although SP-D shows a preference for glucose/maltose, the protein also recognizes D-mannose and a variety of mannose-rich microbial ... Damian C. Ekiert,etc.,al. Antibody Recognition of a Highly Conserved Influenza Virus Epitope. Science DOI: 10.1126/science.1171491. Abstract
submitted by kickingbird at Mar, 1, 2009 from Science DOI: 10.1126/science.1171491 (via http://www.sciencemag.org/cgi/content/abstract/1171491)
Influenza virus presents a significant and persistent threat to public health worldwide, and current vaccines provide immunity to viral isolates similar to the vaccine strain. High-affinity antibodies ... S. Desvaux et al.. Highly Pathogenic Avian Influenza Virus (H5N1) Outbreak in Captive Wild Birds and Cats, Cambodia. Emerg Infect Dis. 2009 Mar. Abstract
submitted by kickingbird at Feb, 23, 2009 from Emerg Infect Dis. 2009 Mar (via http://www.cdc.gov/eid/content/15/3/475.htm?s_cid=eid475_e)
From December 2003 through January 2004, the Phnom Tamao Wildlife Rescue Centre, Cambodia, was affected by the highly pathogenic influenza virus (H5N1). Birds from 26 species died. Influenza virus subtype ... A. Fusaro et al.. Introduction into Nigeria of a Distinct Genotype of Avian Influenza Virus (H5N1). Emerg Infect Dis. 2009 Mar. Abstract
submitted by kickingbird at Feb, 23, 2009 from Emerg Infect Dis. 2009 Mar (via http://www.cdc.gov/eid/content/15/3/445.htm?s_cid=eid445_e)
Genetic characterization of highly pathogenic avian influenza viruses (H5N1) isolated in July 2008 in Nigeria indicates that a distinct genotype, never before detected in Africa, reached the continent. ... G.J.D. Smith et al. Characterization of Avian Influenza Viruses A (H5N1) from Wild Birds, Hong Kong, 2004–2008. Emerg Infect Dis. 2009 Mar. Abstract
submitted by kickingbird at Feb, 23, 2009 from Emerg Infect Dis. 2009 Mar (via http://www.cdc.gov/eid/content/15/3/402.htm?s_cid=eid402_e)
From January 2004 through June 2008, surveillance of dead wild birds in Hong Kong, People's Republic of China, periodically detected highly pathogenic avian influenza (HPAI) viruses (H5N1) in individual ... Laddy DJ, Yan J, Khan AS, Anderson H, Cohn A, Gree. Electroporation of Synthetic DNA Antigens Offers Protection in Non-Human Primates Challenged with Highly Pathogenic Avian Influenza. J Virol. 2009 Feb 11.. Abstract
submitted by kickingbird at Feb, 15, 2009 from J Virol. 2009 Feb 11. (via http://www.ncbi.nlm.nih.gov/pubmed/19211745)
Avian influenza highlights the need for novel vaccination techniques that would allow for the rapid design and production of safe and effective vaccines. An ideal platform would be capable of inducing ... Karron RA, Callahan K, Luke C, Thumar B, McAuliffe. A Live Attenuated H9N2 Influenza Vaccine Is Well Tolerated and Immunogenic in Healthy Adults. J Infect Dis. 2009 Mar 1;199(5):711-716. Abstract
submitted by kickingbird at Feb, 15, 2009 from J Infect Dis. 2009 Mar 1;199(5):711-716 (via http://www.ncbi.nlm.nih.gov/pubmed/19210163)
Development of live attenuated influenza vaccines (LAIV) against avian strains with pandemic potential is an important public-health strategy. Either 1 or 2 10(7)-TCID(50) doses of H9N2 LAIV A/chicken/Hong ... Lipatov AS, Kwon YK, Pantin-Jackwood MJ, Swayne DE. Pathogenesis of H5N1 Influenza Virus Infections in Mice and Ferret Models Differs According to Respiratory Tract or Digestive System Exposure. J Infect Dis. 2009 Mar 1;199(5):717-25.. Abstract
submitted by kickingbird at Feb, 15, 2009 from J Infect Dis. 2009 Mar 1;199(5):717-25. (via http://www.ncbi.nlm.nih.gov/pubmed/19210164)
Background. Epidemiologic, clinical, and laboratory data suggest that H5N1 influenza viruses are transmitted through and predominantly affect the respiratory system of mammals. Some data suggest digestive ... Salomon R, Webster RG.. The influenza virus enigma. Cell. 2009 Feb 6;136(3):402-10. Abstract
submitted by kickingbird at Feb, 15, 2009 from Cell. 2009 Feb 6;136(3):402-10 (via http://www.ncbi.nlm.nih.gov/pubmed/19203576)
Both seasonal and pandemic influenza continue to challenge both scientists and clinicians. Drug-resistant H1N1 influenza viruses have dominated the 2009 flu season, and the H5N1 avian influenza virus continues ... Li Qi, John C. Kash, Vivien G. Dugan, Ruixue Wang,. Role of sialic acid binding specificity of the 1918 influenza virus hemagglutinin protein in virulence and pathogenesis in mice. JVI.02596-08. Abstract
submitted by kickingbird at Feb, 13, 2009 from JVI.02596-08 (via http://jvi.asm.org/cgi/content/abstract/JVI.02596-08v1?papet)
The 1918 influenza pandemic caused over 40 million deaths and likely resulted from introduction and adaptation of a novel avian-like virus. Influenza A virus hemagglutinins are important in host-switching ... Fislová T, Gocník M, Sládková T, Durmanová V, Raj?. Multiorgan distribution of human influenza A virus strains observed in a mouse model. Arch Virol. 2009 Feb 3.. Abstract
submitted by kickingbird at Feb, 8, 2009 from Arch Virol. 2009 Feb 3. (via http://www.ncbi.nlm.nih.gov/pubmed/19189197)
Multiorgan spread and pathogenesis of influenza infection with three human influenza A viruses was studied in mice. Mouse-adapted viruses A/Dunedin/4/73(H3N2), A/Mississippi/1/85(H3N2), and A/PR/8/34(H1N1) ... Takashi Kuzuhara, Daisuke Kise, Hiroko Yoshida, Ta. Structural basis of the influenza A virus RNA polymerase PB2 RNA-binding domain containing the pathogenicity-determinant lysine 627 residue. J. Biol. Chem, 10.1074/jbc.C800224200. Abstract
submitted by kickingbird at Feb, 5, 2009 from J. Biol. Chem, 10.1074/jbc.C800224200 (via http://www.jbc.org/cgi/content/abstract/C800224200v1)
Since the influenza A virus has an RNA genome, its RNA-dependent RNA polymerase, comprising the PA, PB1 and PB2 subunits, is essential for viral transcription and replication. The binding of RNA primers/promoters ... Oleg P Zhirnov, Vladimir V Syrtzev. Influenza virus pathogenicity is determined by caspase cleavage motifs located in viral proteins. J Mol Genet Med (January 2009), 3(1), 124-132. Abstract
submitted by kickingbird at Jan, 23, 2009 from J Mol Genet Med (January 2009), 3(1), 124-132 (via http://www.libpubmedia.co.uk/MedJ-Issues/Issue-4/Zhirnov.htm)
Almost all influenza virus proteins are found to contain caspase cleavage motifs. Two caspase cleavage consensus sequences, EXD|Y and D/EXXD|Y (caspase motifs) were identified in N- and C-terminal regions ... Mosleh, etc.,al. Molecular quantitation of H9N2 avian influenza virus in various organs of broiler chickens using TaqMan real time PCR. J Mol Genet Med (January 2009), 3(1), 152-157. Abstract
submitted by kickingbird at Jan, 23, 2009 from J Mol Genet Med (January 2009), 3(1), 152-157 (via http://www.libpubmedia.co.uk/MedJ-Issues/Issue-4/Mosleh.htm)
During the past decade, H9N2 low pathogenic avian influenza virus (LPAI) has caused considerable economic loss due to decreased production, increased mortality and the cost of vaccination in Iranian poultry ... 5328 items, 20/Page, Page[219/267][|<<] [|<] [211] [212] [213] [214] [215] [216] [217] [218] [219] [220] [>|] [>>|] |
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