CHENG X, Zengel JR, Xu Q, Jin H, et al.. Surface glycoproteins of influenza A H3N2 virus modulate virus replication in the respiratory tract of ferrets. Virology. 2012. Abstract
submitted by kickingbird at Jul, 9, 2012 from Virology. 2012 (via http://www.ncbi.nlm.nih.gov/pubmed/22743127)
The hemagglutinin (HA) genes of the influenza A H3N2 subtype viruses isolated from 1968 to 2010 have evolved substantially but their neuraminidase (NA) genes have been relatively less divergent. The H3N2 ... B. W. Jagger, H. M. Wise, J. C. Kash, K.-A. Walter. An Overlapping Protein-Coding Region in Influenza A Virus Segment 3 Modulates the Host Response. Science DOI: 10.1126/science.1222213. Abstract
submitted by kickingbird at Jul, 1, 2012 from Science DOI: 10.1126/science.1222213 (via http://www.sciencemag.org/content/early/2012/06/27/science.1)
Influenza A virus (IAV) infection leads to variable and imperfectly understood pathogenicity. We report that segment 3 of the virus contains a second open reading frame (“X-ORF”), accessed via ribosomal ... WILKS S, de Graaf M, Smith DJ, Burke DF, et al. A review of influenza haemagglutinin receptor binding as it relates to pandemic properties. Vaccine. 2012 Jun 19;30(29):4369-76.. Abstract
submitted by kickingbird at Jun, 25, 2012 from Vaccine. 2012 Jun 19;30(29):4369-76. (via http://www.ncbi.nlm.nih.gov/pubmed/22682293)
Haemagglutinin is a determinant of many viral properties, and successful adaptation to a human-like form is thought to be an important step toward pandemic influenza emergence. The availability of structurally ... SCHRAUWEN EJ, Herfst S, Leijten LM, van Run P, et. The multibasic cleavage site in H5N1 virus is critical for systemic spread along the olfactory and hematogenous routes in ferrets. J Virol. 2012;86:3975-84. Abstract
submitted by kickingbird at Jun, 25, 2012 from J Virol. 2012;86:3975-84 (via http://www.ncbi.nlm.nih.gov/pubmed/22278228)
The route by which highly pathogenic avian influenza (HPAI) H5N1 virus spreads systemically, including the central nervous system (CNS), is largely unknown in mammals. Especially, the olfactory route, ... O´DONNELL CD, Wright A, Vogel L, Wei CJ, et . The effect of priming with H1N1 influenza viruses of variable antigenic distance on challenge with 2009 pandemic H1N1 virus. J Virol. 2012. Abstract
submitted by kickingbird at Jun, 25, 2012 from J Virol. 2012 (via http://www.ncbi.nlm.nih.gov/pubmed/22674976)
Compared to seasonal influenza viruses, the 2009 pandemic H1N1 (pH1N1) virus caused greater morbidity and mortality in children and young adults. People over 60 years of age showed a higher prevalence ... YANG H, Carney PJ, Donis RO, Stevens J, et al. Structure and receptor complexes of the hemagglutinin from a highly pathogenic H7N7 influenza virus. J Virol. 2012. Abstract
submitted by kickingbird at Jun, 25, 2012 from J Virol. 2012 (via http://www.ncbi.nlm.nih.gov/pubmed/22674977)
Recurrence of highly pathogenic avian influenza (HPAI) subtype H7 in poultry continues to be a public health concern. In 2003, an HPAI H7N7 outbreak in the Netherlands infected 89 people in close contact ... WEEKS-GOROSPE JN, Hurtig HR, Iverson AR, Schuneman. Naturally occurring swine influenza A virus PB1-F2 phenotypes that contribute to super-infection with Gram-positive respiratory pathogens. J Virol. 2012. Abstract
submitted by kickingbird at Jun, 25, 2012 from J Virol. 2012 (via http://www.ncbi.nlm.nih.gov/pubmed/22674997)
A combination of viral, bacterial, and host factors contribute to the severity and overall mortality associated with influenza virus:bacteria super-infections. To date, the virulence associated with the ... NELSON MI, Vincent AL, Kitikoon P, Holmes EC, et a. The evolution of novel reassortant A/H3N2 influenza viruses in North American swine and humans, 2009-2011. J Virol. 2012. Abstract
submitted by kickingbird at Jun, 25, 2012 from J Virol. 2012 (via http://www.ncbi.nlm.nih.gov/pubmed/22696653)
Novel H3N2 influenza viruses (H3N2v) containing seven genome segments from swine-lineage triple reassortant H3N2 viruses and a 2009 pandemic H1N1 (H1N1pdm09) matrix protein segment (pM) have been isolated ... MOISY D, Avilov SV, Jacob Y, Laoide BM, et al. HMGB1 protein binds to influenza virus nucleoprotein and promotes viral replication. J Virol. 2012. Abstract
submitted by kickingbird at Jun, 25, 2012 from J Virol. 2012 (via http://www.ncbi.nlm.nih.gov/pubmed/22696656)
Influenza virus has evolved replication strategies that hijack host cell pathways. To uncover interactions between viral macromolecules and host proteins, we applied a phage display strategy. A library ... REDLBERGER-FRITZ M, Aberle JH, Popow-Kraupp T, Kun. Attributable deaths due to influenza: a comparative study of seasonal and pandemic influenza. Eur J Epidemiol. 2012. Abstract
submitted by kickingbird at Jun, 25, 2012 from Eur J Epidemiol. 2012 (via http://www.ncbi.nlm.nih.gov/pubmed/22678614)
Influenza epidemics lead to an increase in hospitalizations and deaths. Up to now the overall impact of attributable deaths due to seasonal and pandemic influenza viruses in Austria has not been investigated ... HENNING J, Morton JM, Wibawa H, Yulianto D, et al. Incidence and risk factors for H5 highly pathogenic avian influenza infection in flocks of apparently clinically healthy ducks. Epidemiol Infect. 2012. Abstract
submitted by kickingbird at Jun, 25, 2012 from Epidemiol Infect. 2012 (via http://www.ncbi.nlm.nih.gov/pubmed/22687557)
SUMMARYA prospective longitudinal study was conducted on 96 smallholder duck farms in Indonesia over a period of 14 months in 2007 and 2008 to monitor bird- and flock-level incidence rates of H5 highly ... XU K, Ferreri L, Rimondi A, Olivera V, et al. Isolation and characterization of an H9N2 influenza virus isolated in Argentina. Virus Res. 2012. Abstract
submitted by kickingbird at Jun, 25, 2012 from Virus Res. 2012 (via http://www.ncbi.nlm.nih.gov/pubmed/22709552)
As part of our ongoing efforts on animal influenza surveillance in Argentina, an H9N2 virus was isolated from a wild aquatic bird (Netta peposaca), A/rosy-billed pochard/Argentina/CIP051-559/2007 (H9N2)-herein ... VERMA N, Dimitrova M, Carter DM, Crevar CJ, et al.. Influenza virus H1N1pdm09 infections in the young and old: evidence of greater antibody diversity and affinity for the hemagglutinin globular head domain (HA1 Domain) in the elderly than in young adul. J Virol. 2012;86:5515-22. Abstract
submitted by kickingbird at Jun, 25, 2012 from J Virol. 2012;86:5515-22 (via http://www.ncbi.nlm.nih.gov/pubmed/22379097)
The H1N1 2009 influenza virus (H1N1pdm09) pandemic had several unexpected features, including low morbidity and mortality in older populations. We performed in-depth evaluation of antibody responses generated ... BABON JA, Cruz J, Ennis FA, Yin L, et al.. A human CD4+ T cell epitope in the influenza hemagglutinin is cross-reactive to influenza A subtypes and to influenza B virus. J Virol. 2012.. Abstract
submitted by kickingbird at Jun, 25, 2012 from J Virol. 2012. (via http://www.ncbi.nlm.nih.gov/pubmed/22718815)
The hemagglutinin protein (HA) of the influenza virus family is a major antigen for protective immunity. Thus, it is a relevant target for developing vaccines. Here we describe a human CD4(+) T cell epitope ... NELLI RK, Dunham SP, Kuchipudi SV, White GA, et al. Mammalian Innate Resistance to Highly Pathogenic Avian Influenza H5N1 Virus Infection is Mediated through Reduced Pro-inflammation and Infectious Virus Release. J Virol. 2012. Abstract
submitted by kickingbird at Jun, 25, 2012 from J Virol. 2012 (via http://www.ncbi.nlm.nih.gov/pubmed/22718824)
Respiratory epithelial cells and macrophages are the key innate immune cells that play an important role in the pathogenesis of influenza A infection. We found that these two cell types from both human ... QI L, Davis AS, Jagger BW, Schwartzman LM, et al.. Analysis by single gene reassortment demonstrates that the 1918 influenza virus is functionally compatible with a low pathogenicity avian influenza virus in mice. J Virol. 2012.. Abstract
submitted by kickingbird at Jun, 25, 2012 from J Virol. 2012. (via http://www.ncbi.nlm.nih.gov/pubmed/22718825)
The 1918-1919 "Spanish" influenza pandemic is estimated to have caused 50 million deaths worldwide. Understanding the origin, virulence, and pathogenic properties of past pandemic influenza viruses, including ... XU R, Zhu X, McBride R, Nycholat CM, et al.. Functional Balance of the Hemagglutinin and Neuraminidase Activities Accompanies the Emergence of the 2009 H1N1 Influenza Pandemic. J Virol. 2012. Abstract
submitted by kickingbird at Jun, 25, 2012 from J Virol. 2012 (via http://www.ncbi.nlm.nih.gov/pubmed/22718832)
The 2009 H1N1 influenza pandemic is the first human pandemic in decades and was of swine origin. Although swine are believed to be an intermediate host in the emergence of new human influenza viruses, ... MGBEMENA V, Segovia JA, Chang TH, Tsai SY, et al. Transactivation of Inducible Nitric Oxide Synthase Gene by Kruppel-like Factor 6 Regulates Apoptosis during Influenza A Virus Infection. J Immunol. 2012 Jun 18. Abstract
submitted by kickingbird at Jun, 25, 2012 from J Immunol. 2012 Jun 18 (via http://www.ncbi.nlm.nih.gov/pubmed/22711891)
Influenza A virus (flu) is a respiratory tract pathogen causing high morbidity and mortality among the human population. NO is a cellular mediator involved in tissue damage through its apoptosis of target ... WESTGEEST KB, de Graaf M, Fourment M, Bestebroer T. Genetic Evolution of Neuraminidase of Influenza A (H3N2) Viruses from 1968 to 2009 and its Correspondence to Hemagglutinin. J Gen Virol. 2012. Abstract
submitted by kickingbird at Jun, 25, 2012 from J Gen Virol. 2012 (via http://www.ncbi.nlm.nih.gov/pubmed/22718569)
Each year, influenza viruses cause epidemics by evading preexisting humoral immunity through mutations in the major glycoproteins: the hemagglutinin (HA) and the neuraminidase (NA). In 2004, Smith et al. ... CROVILLE G, Soubies SM, Barbieri J, Klopp C, et al. Field Monitoring of Avian Influenza Viruses: Whole Genome Sequencing and Tracking of Neuraminidase Evolution Using 454 Pyrosequencing. J Clin Microbiol. 2012. Abstract
submitted by kickingbird at Jun, 25, 2012 from J Clin Microbiol. 2012 (via http://www.ncbi.nlm.nih.gov/pubmed/22718944)
Adaptation of avian influenza viruses (AIVs) from waterfowl to domestic poultry with a deletion in the neuraminidase (NA) stalk has already been reported. The way the virus undergoes this evolution is ... 5584 items, 20/Page, Page[218/280][|<<] [|<] [211] [212] [213] [214] [215] [216] [217] [218] [219] [220] [>|] [>>|] |
Related Pages:
Browse by Category
Learn about the flu news, articles, events and more
Subscribe to the weekly F.I.C newsletter!
|
- 
