TENG Q, Hu T, Li X, Li G, et al. Complete Genome Sequence of an H3N2 Avian Influenza Virus Isolated from a Live Poultry Market in Eastern China. J Virol. 2012;86:11944. Abstract
submitted by kickingbird at Oct, 14, 2012 from J Virol. 2012;86:11944 (via http://www.ncbi.nlm.nih.gov/pubmed/23043175)
Previous studies indicate that the H3 influenza virus has the ability to establish infection upon interspecies transmission and poses a threat to mammals. Therefore, it is important to enhance the surveillance ... CHEN C, Zhao G, Gu X, Gu M, et al. Complete Genomic Sequence of a Novel Reassortant H11N3 Influenza Virus Isolated from Domestic Ducks in Jiangsu, China. J Virol. 2012;86:11950-1. Abstract
submitted by kickingbird at Oct, 14, 2012 from J Virol. 2012;86:11950-1 (via http://www.ncbi.nlm.nih.gov/pubmed/23043179)
For the first time we report the complete genomic sequence of an H11N3 influenza virus from domestic ducks in China. Phylogenetic analysis showed that the H11N3 virus was a novel reassortant with its genes ... TENG Q, Ji X, Li G, Li X, et al. Complete Genome Sequences of a Novel Reassortant H4N2 Avian Influenza Virus Isolated from a Live Poultry Market in Eastern China. J Virol. 2012;86:11952. Abstract
submitted by kickingbird at Oct, 14, 2012 from J Virol. 2012;86:11952 (via http://www.ncbi.nlm.nih.gov/pubmed/23043180)
A/duck/Shanghai/28-1/2009(H4N2) (DK28) was isolated from a live poultry market in Shanghai, China. Using PCR and sequencing analysis, we obtained the complete genome sequences of the DK28 virus. The sequence ... HSU WB, Shih JL, Shih JR, Du JL, et al. Cellular Protein HAX1 Interacts With Influenza A Virus Polymerase PA Subunit and Impedes Its Nuclear Translocation. J Virol. 2012. Abstract
submitted by kickingbird at Oct, 14, 2012 from J Virol. 2012 (via http://www.ncbi.nlm.nih.gov/pubmed/23055567)
Transcription and replication of the influenza A virus RNA genome occurs in the nucleus through the viral RNA-dependent RNA polymerase consisting of PB1, PB2, and PA. Cellular factors that associate with ... SAKABE S, Takano R, Nagamura-Inoue T, Yamashita N,. Differences in Cytokine Production in Human Macrophages and in Virulence in Mice Are Attributable to the Acidic Polymerase Protein of Highly Pathogenic Influenza A Virus Subtype H5N1. J Infect Dis. 2012. Abstract
submitted by kickingbird at Oct, 14, 2012 from J Infect Dis. 2012 (via http://www.ncbi.nlm.nih.gov/pubmed/23042757)
BackgroundThe pathogenesis of influenza A virus subtype H5N1 (hereafter, "H5N1") infection in humans is not completely understood, although hypercytokinemia is thought to play a role. We previously reported ... WU P, Goldstein E, Ho LM, Yang L, et al.. Excess mortality associated with influenza A and B virus in Hong Kong, 1998-2009. J Infect Dis. 2012. Abstract
submitted by kickingbird at Oct, 14, 2012 from J Infect Dis. 2012 (via http://www.ncbi.nlm.nih.gov/pubmed/23045622)
While deaths associated with laboratory-confirmed influenza virus infections are rare, the excess mortality burden of influenza estimated from statistical models may more reliably quantify the impact of ... TAKANO R, Kiso M, Igarashi M, Le QM, et al. Molecular mechanisms underlying oseltamivir resistance mediated by an I117V substitution in the NA of H5N1 avian influenza viruses. J Infect Dis. 2012. Abstract
submitted by kickingbird at Oct, 14, 2012 from J Infect Dis. 2012 (via http://www.ncbi.nlm.nih.gov/pubmed/23053629)
The neuraminidase (NA) inhibitor oseltamivir is widely used to treat patients infected with influenza viruses. An Ile-to-Val change at position 117 in H5N1 NA (NA-I117V) confers a reduction in susceptibility ... SOUBIES SM, Hoffmann TW, Croville G, Larcher T, et. Deletion of the C-terminal ESEV domain of NS1 does not affect the replication of a low-pathogenic avian influenza virus H7N1 in ducks and chickens. J Gen Virol. 2012. Abstract
submitted by kickingbird at Oct, 14, 2012 from J Gen Virol. 2012 (via http://www.ncbi.nlm.nih.gov/pubmed/23052391)
Highly pathogenic avian influenza (HPAI) H7N1 viruses caused a series of epizootics in Italy between 1999 and 2001. The emergence of these HPAI viruses coincided with the deletion of the six amino acids ... YAO Y, Wang H, Chen Q, Zhang H, et al. Characterization of low-pathogenic H6N6 avian influenza viruses in central China. Arch Virol. 2012. Abstract
submitted by kickingbird at Oct, 14, 2012 from Arch Virol. 2012 (via http://www.ncbi.nlm.nih.gov/pubmed/23053524)
Three strains of H6N6 subtype avian influenza virus (AIV) were isolated from live-poultry markets of central China during 2009-2010. A phylogenetic analysis showed that these isolates originated from gene ... BUI VN, Ogawa H, Ngo LH, Baatartsogt T, et al. H5N1 highly pathogenic avian influenza virus isolated from conjunctiva of a whooper swan with neurological signs. Arch Virol. 2012. Abstract
submitted by kickingbird at Oct, 14, 2012 from Arch Virol. 2012 (via http://www.ncbi.nlm.nih.gov/pubmed/23053526)
An H5N1 highly pathogenic avian influenza virus was isolated from conjunctiva of a whooper swan with neurological signs, which was captured during the latest H5N1 HPAI outbreak in Japan. The conjunctival ... STANEKOVA Z, Adkins I, Kosova M, Janulikova J, et. Heterosubtypic protection against influenza induced by adenylate cyclase toxoids delivering conserved HA2 subunit of hemagglutinin. Antiviral Res. 2012 Oct 1. pii: S0166-3542(12)0020. Abstract
submitted by kickingbird at Oct, 14, 2012 from Antiviral Res. 2012 Oct 1. pii: S0166-3542(12)0020 (via http://www.ncbi.nlm.nih.gov/pubmed/23036818)
The protective efficacy of currently available influenza vaccines is restricted to vaccine strains and their close antigenic variants. A new strategy to obtain a cross-protection against influenza is based ... DIMMOCK NJ, Dove BK, Meng B, Scott PD, et al. Comparison of the protection of ferrets against pandemic 2009 influenza A virus (H1N1) by 244 DI influenza virus and oseltamivir. Antiviral Res. 2012 Oct 4. pii: S0166-3542(12)0022. Abstract
submitted by kickingbird at Oct, 14, 2012 from Antiviral Res. 2012 Oct 4. pii: S0166-3542(12)0022 (via http://www.ncbi.nlm.nih.gov/pubmed/23041142)
The main antivirals employed to combat seasonal and pandemic influenza are oseltamivir and zanamivir which act by inhibiting the virus-encoded neuraminidase. These have to be deployed close to the time ... UCHIDA Y, Suzuki Y, Shirakura M, Kawaguchi A, et a. Genetics and infectivity of H5N1 highly pathogenic avian influenza viruses isolated from chickens and wild birds in Japan during 2010-11. Virus Res. 2012 Sep 19. pii: S0168-1702(12)00322.. Abstract
submitted by kickingbird at Oct, 8, 2012 from Virus Res. 2012 Sep 19. pii: S0168-1702(12)00322. (via http://www.ncbi.nlm.nih.gov/pubmed/23000396)
Outbreaks of H5N1 subtype highly pathogenic avian influenza virus (HPAIV) were recorded in chickens, domesticated birds and wild birds throughout Japan from November 2010 to March 2011. Genetic analysis ... TAKASHITA E, Muraki Y, Sugawara K, Asao H, et al. Intrinsic Temperature Sensitivity of Influenza C Virus Hemagglutinin-Esterase-Fusion Protein. J Virol. 2012. Abstract
submitted by kickingbird at Oct, 8, 2012 from J Virol. 2012 (via http://www.ncbi.nlm.nih.gov/pubmed/23015703)
Influenza C virus replicates more efficiently at 33°C than at 37°C. To determine whether hemagglutinin-esterase-fusion protein (HEF), a surface glycoprotein of influenza C virus, is a restricting factor ... ZHU X, McBride R, Nycholat CM, Yu W, et al. Influenza virus neuraminidases with reduced enzymatic activity that avidly bind sialic acid receptors. J Virol. 2012. Abstract
submitted by kickingbird at Oct, 8, 2012 from J Virol. 2012 (via http://www.ncbi.nlm.nih.gov/pubmed/23015718)
Influenza neuraminidase (NA) cleaves off sialic acid from cellular receptors of hemagglutinin (HA) to enable progeny escape from infected cells. However, NA variants (D151G) of recent human H3N2 viruses ... HAYNES L, Szaba FM, Eaton SM, Kummer LW, et al. Immunity to the Conserved Influenza Nucleoprotein Reduces Susceptibility to Secondary Bacterial Infections. J Immunol. 2012. Abstract
submitted by kickingbird at Oct, 8, 2012 from J Immunol. 2012 (via http://www.ncbi.nlm.nih.gov/pubmed/23028058)
Influenza causes >250,000 deaths annually in the industrialized world, and bacterial infections frequently cause secondary illnesses during influenza outbreaks, including pneumonia, bronchitis, sinusitis, ... KANG HM, Choi JG, Kim KI, Park HY, et al. Genetic and antigenic characteristics of H4 subtype avian influenza viruses in Korea and their pathogenicity in quails, domestic ducks and mice. J Gen Virol. 2012. Abstract
submitted by kickingbird at Oct, 8, 2012 from J Gen Virol. 2012 (via http://www.ncbi.nlm.nih.gov/pubmed/23015746)
In Korea, a nationwide surveillance program has been implemented to identify highly pathogenic avian influenza virus since 2003. Avian influenza viruses (AIVs) belonging to one of the most common haemagglutinin ... YAMADA H, Moriishi E, Haredy AM, Takenaka N, et al. Influenza virus neuraminidase contributes to the dextran sulfate-dependent suppressive replication of some influenza A virus strains. Antiviral Res. 2012 Sep 26. pii: S0166-3542(12)002. Abstract
submitted by kickingbird at Oct, 8, 2012 from Antiviral Res. 2012 Sep 26. pii: S0166-3542(12)002 (via http://www.ncbi.nlm.nih.gov/pubmed/23022352)
Dextran sulfate (DS), a negatively charged, sulfated polysaccharide, suppresses the replication of an influenza A virus strain, and this suppression is associated with inhibition of the hemagglutinin (HA)-dependent ... LU X, Shi Y, Gao F, Xiao H, et al. Insights into avian influenza virus pathogenicity: the hemagglutinin precursor HA0 of H16 subtype has an alpha-helix structure in its cleavage site with an inefficient HA1/HA2 cleavage. J Virol. 2012. Abstract
submitted by kickingbird at Sep, 24, 2012 from J Virol. 2012 (via http://www.ncbi.nlm.nih.gov/pubmed/22993148)
With a new serotype (H17) hemagglutinin (HA) recently being discovered, there are now 17 serotypes (H1-H17) of influenza A viruses in total. It is believed that HA is initially expressed as a precursor ... AYLLON J, Russell RJ, Garcia-Sastre A, Hale BG, et. Contribution of NS1 effector domain dimerization to influenza A virus replication and virulence. J Virol. 2012. Abstract
submitted by kickingbird at Sep, 24, 2012 from J Virol. 2012 (via http://www.ncbi.nlm.nih.gov/pubmed/22993153)
Conserved tryptophan-187 facilitates homodimerization of the influenza A virus NS1 effector domain. We generated a mutant influenza virus expressing NS1-W187R to destabilize this self-interaction. NS1-W187R ... 5584 items, 20/Page, Page[216/280][|<<] [|<] [211] [212] [213] [214] [215] [216] [217] [218] [219] [220] [>|] [>>|] |
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