Zaraket H, Bridges OA, Russell CJ.. The pH of Activation of the Hemagglutinin Protein Regulates H5N1 Influenza Virus Replication and Pathogenesis in Mice. J Virol. 2013 Feb 28. Abstract
submitted by kickingbird at Mar, 6, 2013 from J Virol. 2013 Feb 28 (via http://www.ncbi.nlm.nih.gov/pubmed/23449784)
After receptor binding and internalization during influenza virus entry, the hemagglutinin (HA) protein is triggered by low pH to undergo irreversible conformational changes that mediate membrane fusion. ... TSE LV, Marcano VC, Huang W, Pocwierz MS, et al. Plasmin-mediated activation of pandemic H1N1 influenza virus hemagglutinin independent of the viral neuraminidase. J Virol. 2013 Feb 28. Abstract
submitted by kickingbird at Mar, 6, 2013 from J Virol. 2013 Feb 28 (via http://www.ncbi.nlm.nih.gov/pubmed/23449787)
Influenza virus is well recognized to modulate host tropism and pathogenesis based on mutations in the proteolytic cleavage site of the viral hemagglutinin (HA), which activates HA and exposes the fusion ... DERMODY TS, Sandri-Goldin RM, Shenk T. A New Determinant of H5N1 Influenza Virus Pathogenesis in Mammals. J Virol. 2013 Feb 28. Abstract
submitted by kickingbird at Mar, 6, 2013 from J Virol. 2013 Feb 28 (via http://www.ncbi.nlm.nih.gov/pubmed/23449798)
In this issue of the Journal of Virology, we publish a paper by Hassan Zaraket, Olga A. Bridges, and Charles J. Russell from St. Jude Children's Research Hospital reporting a sequence polymorphism in the ... TAKEMAE N, Nguyen T, Ngo LT, Hiromoto Y, et al. Antigenic variation of H1N1, H1N2 and H3N2 swine influenza viruses in Japan and Vietnam. Arch Virol. 2013 Feb 23. Abstract
submitted by kickingbird at Mar, 6, 2013 from Arch Virol. 2013 Feb 23 (via http://www.ncbi.nlm.nih.gov/pubmed/23435952)
The antigenicity of the influenza A virus hemagglutinin is responsible for vaccine efficacy in protecting pigs against swine influenza virus (SIV) infection. However, the antigenicity of SIV strains currently ... H.K.K. Perera et al. Swine Influenza in Sri Lanka. EID Volume 19, Number 3—March 2013. Abstract
submitted by kickingbird at Mar, 2, 2013 from EID Volume 19, Number 3—March 2013 (via http://wwwnc.cdc.gov/eid/article/19/3/12-0945_article.htm)
Abstract
To study influenza viruses in pigs in Sri Lanka, we examined samples from pigs at slaughterhouses. Influenza (H3N2) and A(H1N1)pdm09 viruses were prevalent during 2004–2005 and 2009–2012, respectively. ... R. Bodewes et al. Recurring Influenza B Virus Infections in Seals. EID Volume 19, Number 3—March 2013. Abstract
submitted by kickingbird at Mar, 2, 2013 from EID Volume 19, Number 3—March 2013 (via http://wwwnc.cdc.gov/eid/article/19/3/12-0965_article.htm)
To the Editor: Until 1999, influenza B virus was considered to infect humans only. However, more recent data proved that harbor seals (Phoca vitulina) and gray seals (Halichoerus grypus) also can be infected ... Elizabeth Miller,etc.,al. Risk of narcolepsy in children and young people receiving AS03 adjuvanted pandemic A/H1N1 2009 influenza vaccine: retrospective analysis. BMJ 2013;346:f794. Abstract
submitted by kickingbird at Feb, 28, 2013 from BMJ 2013;346:f794 (via http://www.bmj.com/content/346/bmj.f794)
Objective To evaluate the risk of narcolepsy in children and adolescents in England targeted for vaccination with ASO3 adjuvanted pandemic A/H1N1 2009 vaccine (Pandemrix) from October 2009.
Design Retrospective ... COHEN S, Janicki-Deverts D, Turner RB, Casselbrant. Association between telomere length and experimentally induced upper respiratory viral infection in healthy adults. JAMA. 2013 Feb 20;309(7):699-705.. Abstract
submitted by kickingbird at Feb, 25, 2013 from JAMA. 2013 Feb 20;309(7):699-705. (via http://www.ncbi.nlm.nih.gov/pubmed/23423415)
Abstract
IMPORTANCE:
Although leukocyte telomere length is associated with mortality and many chronic diseases thought to be manifestations of age-related functional decline, it is not known whether ... PERRONE LA, Belser JA, Wadford DA, Katz JM, et al. Inducible nitric oxide contributes to viral pathogenesis following highly pathogenic influenza virus infection in mice. J Infect Dis. 2013. Abstract
submitted by kickingbird at Feb, 25, 2013 from J Infect Dis. 2013 (via http://www.ncbi.nlm.nih.gov/pubmed/23420903)
Highly pathogenic influenza A viruses including avian H5N1 viruses and the 1918 pandemic virus cause severe respiratory disease in humans and animals. Virus infection is followed by intense pulmonary congestion ... CILLONIZ C, Ewig S, Menendez R, Ferrer M, et al. Bacterial co-infection with H1N1 infection in patients admitted with community acquired pneumonia. J Infect. 2012;65:223-30. Abstract
submitted by kickingbird at Feb, 25, 2013 from J Infect. 2012;65:223-30 (via http://www.ncbi.nlm.nih.gov/pubmed/22543245)
BACKGROUND:
Bacterial co-infection is an important contributor to morbidity and mortality during influenza pandemics .We investigated the incidence, risk factors and outcome of patients with influenza ... GAO X, Wang W, Li Y, Zhang S, et al. Enhanced Influenza VLP Vaccines Comprising Matrix-2 Ectodomain and Nucleoprotein Epitopes Protects mice from Lethal Challenge. Antiviral Res. 2013 Feb 14. pii: S0166-3542(13)000. Abstract
submitted by kickingbird at Feb, 25, 2013 from Antiviral Res. 2013 Feb 14. pii: S0166-3542(13)000 (via http://www.ncbi.nlm.nih.gov/pubmed/23416215)
The matrix protein 2ectodomain (M2e) of the influenza A virus is a rational target antigen candidate for the development of a universal influenza virus-like particle (VLP) vaccine. In this study, a recombinant ... MURCIA PR, Baillie GJ, Stack JC, Jervis C, et al. Evolution of equine influenza virus in vaccinated horses. J Virol. 2013 Feb 6. Abstract
submitted by kickingbird at Feb, 24, 2013 from J Virol. 2013 Feb 6 (via http://www.ncbi.nlm.nih.gov/pubmed/23388708)
Influenza A viruses are characterized by their ability to evade host immunity, even in vaccinated individuals. To determine how prior immunity shapes viral diversity in vivo we studied the intra- and inter-host ... ALFONSO R, Rodriguez A, Rodriguez P, Lutz T, et al. CHD6, a cellular repressor of influenza virus replication is degraded in human alveolar epithelial cells and mice lungs during infection. J Virol. 2013 Feb 13. Abstract
submitted by kickingbird at Feb, 24, 2013 from J Virol. 2013 Feb 13 (via http://www.ncbi.nlm.nih.gov/pubmed/23408615)
The influenza virus polymerase associates to an important number of transcription related proteins including the largest subunit of the RNA polymerase II complex (RNAP II). Despite this association, degradation ... YOON SW, Kayali G, Ali MA, Webster RG, et al. A Single Amino Acid at the Hemagglutinin Cleavage Site Contributes to the Pathogenicity but not Transmission of Egyptian Highly Pathogenic H5N1 Influenza Virus in Chickens. J Virol. 2013 Feb 13.. Abstract
submitted by kickingbird at Feb, 24, 2013 from J Virol. 2013 Feb 13. (via http://www.ncbi.nlm.nih.gov/pubmed/23408622)
Highly pathogenic avian influenza H5N1 has been enzootic in Egypt since 2008. Virus-associated mortality (but not the number of cases) in humans and poultry seems to have decreased over time, but the reason ... FAN S, Macken CA, Li C, Ozawa M, et al. Synergistic effect of the PDZ and the p85β-binding domains of the NS1 protein in virulence of an avian H5N1 influenza A virus. J Virol. 2013 Feb 13. Abstract
submitted by kickingbird at Feb, 24, 2013 from J Virol. 2013 Feb 13 (via http://www.ncbi.nlm.nih.gov/pubmed/23408626)
The influenza A virus NS1 protein affects virulence through several mechanisms including the host's innate immune response and various signaling pathways. Highly pathogenic avian influenza (HPAI) viruses ... MARGINE I, Hai R, Albrecht RA, Obermoser G, et al. H3N2 influenza virus infection induces broadly reactive hemagglutinin stalk antibodies in humans and mice. J Virol. 2013 Feb 13.. Abstract
submitted by kickingbird at Feb, 24, 2013 from J Virol. 2013 Feb 13. (via http://www.ncbi.nlm.nih.gov/pubmed/23408625)
Broadly neutralizing antibodies directed against the conserved stalk domain of the viral hemagglutinin have attracted increasing attention in the recent years. However, only a limited number of stalk antibodies ... ZHANG L, Guo ZW, Bridge ES, Li YM, et al. Distribution and dynamics of risk factors associated with highly pathogenic avian influenza H5N1. Epidemiol Infect. 2013 Feb 11:1-10.. Abstract
submitted by kickingbird at Feb, 24, 2013 from Epidemiol Infect. 2013 Feb 11:1-10. (via http://www.ncbi.nlm.nih.gov/pubmed/23398949)
SUMMARY Within China's Poyang Lake region, close interactions between wild migratory birds and domestic poultry are common and provide an opportunity for the transmission and subsequent outbreaks of highly ... CLAES G, Welby S, VAN DEN Berg T, VAN DER Stede Y,. The impact of viral tropism and housing conditions on the transmission of three H5/H7 low pathogenic avian influenza viruses in chickens. Epidemiol Infect. 2013 Feb 11:1-16. Abstract
submitted by kickingbird at Feb, 24, 2013 from Epidemiol Infect. 2013 Feb 11:1-16 (via http://www.ncbi.nlm.nih.gov/pubmed/23398968)
SUMMARY In this study, shedding and transmission of three H5/H7 low pathogenic avian influenza viruses (LPAIVs) in poultry was characterized and the impact of floor system on transmission was assessed. ... Falcone V, Bierbaum S, Kern W, Kontny U, Bertz H,. Influenza virus A(H1N1)pdm09 hemagglutinin polymorphism and associated disease in southern Germany during the 2010/11 influenza season. Arch Virol. 2013 Feb 9.. Abstract
submitted by kickingbird at Feb, 24, 2013 from Arch Virol. 2013 Feb 9. (via http://www.ncbi.nlm.nih.gov/pubmed/23397331)
A novel influenza A virus emerged in early 2009 to cause the first influenza pandemic of the 21(st) century. Understanding the evolution of influenza virus is crucial to determine pathogenesis, vaccine ... Wang Y, Landman B, Wu C, Gelb J, Golovan S.. Comparison of vRNA and cRNA based reporters for detection of influenza replication. Antiviral Res. 2013 Feb 9.. Abstract
submitted by kickingbird at Feb, 24, 2013 from Antiviral Res. 2013 Feb 9. (via http://www.ncbi.nlm.nih.gov/pubmed/23403209)
In this study, RNA polymerase I expressed replicons containing EGFP and luciferase reporter genes controlled by influenza vRNA or cRNA promoters were compared side-by-side in the ability to detect influenza ... 5584 items, 20/Page, Page[213/280][|<<] [|<] [211] [212] [213] [214] [215] [216] [217] [218] [219] [220] [>|] [>>|] |
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