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Ilyinskii PO, Schmidt T, Lukashev D, Meriin AB, Th. Importance of mRNA Secondary Structural Elements for the Expression of Influenza Virus Genes. OMICS. 2009 Jul 13..  Abstract  
submitted by kickingbird at Jul, 16, 2009 from OMICS. 2009 Jul 13. (via http://www.ncbi.nlm.nih.gov/pubmed/19594376?ordinalpos=28&it)
Development of novel vaccines and therapeutics often requires efficient expression of recombinant viral proteins. Here we show that mutations in essential functional regions of conserved influenza proteins ...

Husain M, Harrod KS. Influenza A virus-induced caspase-3 cleaves the histone deacetylase 6 in infected epithelial cells. FEBS Lett. 2009 Jul 10.  Abstract  
submitted by kickingbird at Jul, 16, 2009 from FEBS Lett. 2009 Jul 10 (via http://www.ncbi.nlm.nih.gov/pubmed/19596000?ordinalpos=24&it)
Histone deacetylase 6 (HDAC6) is a multi-substrate cytoplasmic enzyme that regulates many important biological processes. Recently, some reports have implicated HDAC6 in viral infection. However, nothing ...

Yamanaka T, Nemoto M, Tsujimura K, Kondo T, Matsum. Interspecies transmission of equine influenza virus (H3N8) to dogs by close contact with experimentally infected horses. Vet Microbiol. 2009 Jun 21..  Abstract  
submitted by kickingbird at Jul, 16, 2009 from Vet Microbiol. 2009 Jun 21. (via http://www.ncbi.nlm.nih.gov/pubmed/19596528?ordinalpos=20&it)
In horse populations, influenza A virus subtype H3N8 (equine influenza virus, EIV) is a very important pathogen that leads to acute respiratory disease. Recently, EIV has emerged in dogs, and has become ...

Chan RW, Chan MC, Wong AC, Karamanska R, Dell A, H. DAS181 Inhibits H5N1 Influenza virus Infection of Human Lung Tissues. Antimicrob Agents Chemother. 2009 Jul 13.  Abstract  
submitted by kickingbird at Jul, 16, 2009 from Antimicrob Agents Chemother. 2009 Jul 13 (via http://www.ncbi.nlm.nih.gov/pubmed/19596886?ordinalpos=14&it)
DAS181 is a novel therapeutic candidate against influenza virus which functions via the mechanism of removing the virus receptor, sialic acid (Sia) from the adjacent glycan structures. DAS181 and its analogues ...

Smith GJ, Bahl J, Vijaykrishna D, Zhang J, Poon LL. Dating the emergence of pandemic influenza viruses. Proc Natl Acad Sci U S A. 2009 Jul 13.  Abstract  
submitted by kickingbird at Jul, 16, 2009 from Proc Natl Acad Sci U S A. 2009 Jul 13 (via http://www.ncbi.nlm.nih.gov/pubmed/19597152?ordinalpos=12&it)
Pandemic influenza viruses cause significant mortality in humans. In the 20th century, 3 influenza viruses caused major pandemics: the 1918 H1N1 virus, the 1957 H2N2 virus, and the 1968 H3N2 virus. These ...

Vincent AL, Ma W, Lager KM, Gramer MR, Richt JA, J. Characterization of a newly emerged genetic cluster of H1N1 and H1N2 swine influenza virus in the United States. Virus Genes. 2009 Jul 14.  Abstract  
submitted by kickingbird at Jul, 16, 2009 from Virus Genes. 2009 Jul 14 (via http://www.ncbi.nlm.nih.gov/pubmed/19597980?ordinalpos=9&ito)
H1 influenza A viruses that were distinct from the classical swine H1 lineage were identified in pigs in Canada in 2003-2004; antigenic and genetic characterization identified the hemagglutinin (HA) as ...

Yang W, Qu S, Liu Q, Zheng C. Avian influenza virus A/chicken/Hubei/489/2004 (H5N1) induces caspase-dependent apoptosis in a cell-specific manner. Mol Cell Biochem. 2009 Jul 14.  Abstract  
submitted by kickingbird at Jul, 16, 2009 from Mol Cell Biochem. 2009 Jul 14 (via http://www.ncbi.nlm.nih.gov/pubmed/19597767?ordinalpos=10&it)
The economic damage caused by H5N1 avian influenza virus outbreak in domestic poultry and the threat of this virus to human health make the research of this virus highly significant. During the 2004 outbreak ...

Cady SD, Luo W, Hu F, Hong M.. Structure and Function of the Influenza A M2 Proton Channel. Biochemistry. 2009 Jul 14.  Abstract  
submitted by kickingbird at Jul, 16, 2009 from Biochemistry. 2009 Jul 14 (via http://www.ncbi.nlm.nih.gov/pubmed/19601584?ordinalpos=7&ito)
The M2 protein of influenza A viruses forms a tetrameric pH-activated proton-selective channel that is targeted by the amantadine class of antiviral drugs. Its ion channel function has been extensively ...

Cross KJ, Langley WA, Russell RJ, Skehel JJ, Stein. Composition and functions of the influenza fusion peptide. Protein Pept Lett. 2009;16(7):766-78.  Abstract  
submitted by kickingbird at Jul, 16, 2009 from Protein Pept Lett. 2009;16(7):766-78 (via http://www.ncbi.nlm.nih.gov/pubmed/19601906?ordinalpos=5&ito)
Fusion of the influenza virus envelope with the endosomal membrane of host cells is mediated by the hemagglutinin glycoprotein (HA). The most conserved region of HA is at the N-terminus of the HA2 subunit, ...

Yan S, Wu G. Describing evolution of hemagglutinins from influenza a viruses using a differential equation. Protein Pept Lett. 2009;16(7):794-804.  Abstract  
submitted by kickingbird at Jul, 16, 2009 from Protein Pept Lett. 2009;16(7):794-804 (via http://www.ncbi.nlm.nih.gov/pubmed/19601909?ordinalpos=4&ito)
Since 1999 we have developed three approaches to quantifying each amino acid in a protein as well as a protein in whole based on random mechanisms. With our approaches, we can reliably describe the evolution ...

Camitz M.. StatFlu - a static modelling tool for pandemic influenza hospital load for decision makers. Euro Surveill. 2009;14(26):pii=19256..  Full Text  
submitted by kickingbird at Jul, 16, 2009 from Euro Surveill. 2009;14(26):pii=19256. (via http://www.eurosurveillance.org/ViewArticle.aspx?ArticleId=1)
Introduction Many successful models using dynamic simulations to estimate the effect of an influenza pandemic have been presented and have been essential in providing the knowledge needed for pandemic ...

Cruz-Pacheco G, Duran L, Esteva L, Minzoni AA, Lóp. Modelling of the influenza A(H1N1)v outbreak in Mexico City, April-May 2009, with control sanitary measures. Euro Surveill. 2009;14(26):pii=19254.  Full Text  
submitted by kickingbird at Jul, 16, 2009 from Euro Surveill. 2009;14(26):pii=19254 (via http://www.eurosurveillance.org/ViewArticle.aspx?ArticleId=1)
Introduction                                                             ...

Hahné S, Donker T, Meijer A, Timen A, van Steenber. Epidemiology and control of influenza A(H1N1)v in the Netherlands: the first 115 cases. Euro Surveill. 2009;14(27):pii=19267.  Full Text  
submitted by kickingbird at Jul, 16, 2009 from Euro Surveill. 2009;14(27):pii=19267 (via http://www.eurosurveillance.org/ViewArticle.aspx?ArticleId=1)
IntroductionThe first human infections with the new influenza A(H1N1) variant virus [A(H1N1)v], a novel triple reassortant swine influenza virus, were diagnosed in two patients in the United States on ...

Munster VJ, de Wit E, van den Brand JM, Herfst S,. Pathogenesis and Transmission of Swine-Origin 2009 A(H1N1) Influenza Virus in Ferrets. Science. 2009 Jul 2.  Abstract  
submitted by kickingbird at Jul, 5, 2009 from Science. 2009 Jul 2 (via http://www.sciencemag.org/cgi/content/abstract/1177127v1)
The swine-origin influenza A(H1N1) virus that has emerged in humans in early 2009 has raised concerns about pandemic developments. In a ferret pathogenesis and transmission model, the 2009 A(H1N1) virus ...

Maines TR, Jayaraman A, Belser JA, Wadford DA, Pap. Transmission and Pathogenesis of Swine-Origin 2009 A(H1N1) Influenza Viruses in Ferrets and Mice. Science. 2009 Jul 2.  Abstract  
submitted by kickingbird at Jul, 5, 2009 from Science. 2009 Jul 2 (via http://www.sciencemag.org/cgi/content/abstract/1177238v1)
Recent reports of mild to severe influenza-like illness in humans caused by a novel swine-origin 2009 A(H1N1) influenza virus underscore the need to better understand the pathogenesis and transmission ...

N Wilson and M G Baker. The emerging influenza pandemic: estimating the case fatality ratio. Eurosurveillance, Volume 14, Issue 26, 2009.  Abstract  
submitted by kickingbird at Jul, 3, 2009 from Eurosurveillance, Volume 14, Issue 26, 2009 (via http://www.eurosurveillance.org/ViewArticle.aspx?ArticleId=1)
To determine appropriate influenza pandemic containment and mitigation measures, health authorities need to know the approximate case fatality ratio (CFR) for this new infection. We present four different ...

Chowell D, Bertozzi S, Arantxa Colchero M et al.. Severe Respiratory Disease Concurrent with the Circulation of H1N1 Influenza. N Engl J Med 2009 (published online Jun 29).  Abstract  
submitted by kickingbird at Jun, 30, 2009 from N Engl J Med 2009 (published online Jun 29) (via http://content.nejm.org/cgi/content/full/NEJMoa0904252)
Background In the spring of 2009, an outbreak of severe pneumonia was reported in conjunction with the concurrent isolation of a novel swine-origin influenza A (H1N1) virus (S-OIV), widely known as swine ...

Perez-Padilla R, de la Rosa-Zamboni D, Ponce de Le. Pneumonia and Respiratory Failure from Swine-Origin Influenza A (H1N1) in Mexico. N Engl J Med 2009 (published online Jun 29).  Abstract  
submitted by kickingbird at Jun, 30, 2009 from N Engl J Med 2009 (published online Jun 29) (via http://content.nejm.org/cgi/content/full/NEJMoa0904252)
Background In late March 2009, an outbreak of a respiratory illness later proved to be caused by novel swine-origin influenza A (H1N1) virus (S-OIV) was identified in Mexico. We describe the clinical and ...

Nofs S, Abd-Eldaim M, Thomas KV, Toplon D, Rouse D. Influenza Virus A (H1N1) in Giant Anteaters (Myrmecophaga tridactyla). Emerg Infect Dis 2009 July.  Abstract  
submitted by kickingbird at Jun, 27, 2009 from Emerg Infect Dis 2009 July (via http://www.cdc.gov/eid/content/15/7/1081.htm)
In February 2007, an outbreak of respiratory disease occurred in a group of giant anteaters (Myrmecophaga tridactyla) at the Nashville Zoo. Isolates from 2 affected animals were identified in March 2007 ...

zu Dohna H, Li J, Cardona CJ, Miller J, Carpenter. Invasions by Eurasian Avian Influenza Virus H6 Genes and Replacement of the Virus´ North American Clade. Emerg Infect Dis 2009 Jul.  Abstract  
submitted by kickingbird at Jun, 27, 2009 from Emerg Infect Dis 2009 Jul (via http://www.cdc.gov/eid/content/15/7/1040.htm)
The spread of highly pathogenic avian influenza virus (AIV) (H5N1) underlines the potential for global AIV movement through birds. The phylogenies of AIV genes from avian hosts usually separate into Eurasian ...

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