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A. Gomez-Gomez et al.. Severe Pneumonia Associated with Pandemic (H1N1) 2009 Outbreak, San Luis Potosí, Mexico. EID Volume 16, Number 1–January 2010.  Abstract  
submitted by kickingbird at Dec, 23, 2009 from EID Volume 16, Number 1–January 2010 (via http://www.cdc.gov/EID/content/16/1/27.htm)
AbstractWe describe the clinical characteristics and outcomes of adults hospitalized with pneumonia during the pandemic (H1N1) 2009 outbreak. Patients admitted to a general hospital in San Luis Potosí, ...

Fleury H, Burrel S, Balick Weber C, Hadrien R, Bla. Prolonged shedding of influenza A(H1N1)v virus: two case reports from France 2009. Eurosurveillance, Volume 14, Issue 49.  Abstract  
submitted by kickingbird at Dec, 11, 2009 from Eurosurveillance, Volume 14, Issue 49 (via http://www.eurosurveillance.org/ViewArticle.aspx?ArticleId=1)
We observed a prolonged shedding of virus 14 and 28 days after symptom onset in two patients with pandemic H1N1 influenza, who did not have immunodepression and were treated with neuraminidase inhibitor. ...

Ayora-Talavera G, Shelton H, Scull MA, Ren J, Jone. Mutations in H5N1 Influenza Virus Hemagglutinin that Confer Binding to Human Tracheal Airway Epithelium. PLoS ONE 4(11): e7836. doi:10.1371/journal.pone.00.  Abstract  
submitted by kickingbird at Nov, 24, 2009 from PLoS ONE 4(11): e7836. doi:10.1371/journal.pone.00 (via http://www.plosone.org/article/info:doi/10.1371/journal.pone)
The emergence in 2009 of a swine-origin H1N1 influenza virus as the first pandemic of the 21st Century is a timely reminder of the international public health impact of influenza viruses, even those associated ...

Monica Schoch-Spana, Nidhi Bouri, Ann Norwood and. Preliminary Findings: Study of the Impact of the 2009 H1N1 Influenza Pandemic on Latino Migrant Farm Workers in the U.S. UPMC.  Abstract  
submitted by kickingbird at Nov, 24, 2009 from UPMC (via http://www.upmc-cbn.org/report_archive/h1n1/issue_briefs/200)
In the summer of 2009, the Center for Biosecurity of UPMC sought to investigate social threats to the health and well-being of Latino migrant and seasonal farm workers (MSFWs) in the U.S. in connection ...

Das P, Li J, Royyuru AK, Zhou R.. Free energy simulations reveal a double mutant avian H5N1 virus hemagglutinin with altered receptor binding specificity. J Comput Chem. 2009 Aug;30(11):1654-63.  Abstract  
submitted by kickingbird at Oct, 19, 2009 from J Comput Chem. 2009 Aug;30(11):1654-63 (via http://www.ncbi.nlm.nih.gov/pubmed/19399777?ordinalpos=1&ito)
Historically, influenza pandemics have been triggered when an avian influenza virus or a human/avian reassorted virus acquires the ability to replicate efficiently and become transmissible in the human ...

The Australia and New Zealand Extracorporeal Membr. Extracorporeal Membrane Oxygenation for 2009 Influenza A(H1N1) Acute Respiratory Distress Syndrome. JAMA. 2009 Oct 12.  Abstract  
submitted by kickingbird at Oct, 19, 2009 from JAMA. 2009 Oct 12 (via http://www.ncbi.nlm.nih.gov/pubmed/19822628)
CONTEXT: The novel influenza A(H1N1) pandemic affected Australia and New Zealand during the 2009 southern hemisphere winter. It caused an epidemic of critical illness and some patients developed severe ...

Steel J, Staeheli P, Mubareka S, García-Sastre A,. Transmission of pandemic H1N1 influenza virus and impact of prior exposure to seasonal strains or interferon treatment. J Virol. 2009 Oct 14.  Abstract  
submitted by kickingbird at Oct, 19, 2009 from J Virol. 2009 Oct 14 (via http://www.ncbi.nlm.nih.gov/pubmed/19828604)
Novel, swine origin influenza viruses of the H1N1 subtype were first detected in humans in April 2009. As of Aug 12th, 180,000 cases had been reported globally. Despite the fact that they are of the same ...

McAuley JL, Zhang K, McCullers JA.. The effects of influenza A virus PB1-F2 protein on polymerase activity are strain specific and do not impact pathogenesis. J Virol. 2009 Oct 14..  Abstract  
submitted by kickingbird at Oct, 19, 2009 from J Virol. 2009 Oct 14. (via http://www.ncbi.nlm.nih.gov/pubmed/19828614)
The influenza A virus PB1-F2 protein has been implicated as a virulence factor, but the mechanism by which it enhances pathogenicity is not understood. The PB1 gene segment of the H1N1 swine-origin influenza ...

Chen SC, Liao CM.. Probabilistic indoor transmission modeling for influenza (sub)type viruses in Taiwan. J Infect. 2009 Oct 6.  Abstract  
submitted by kickingbird at Oct, 19, 2009 from J Infect. 2009 Oct 6 (via http://www.ncbi.nlm.nih.gov/pubmed/19818365)
OBJECTIVES: To use a probability based transmission modeling approach to examine the influenza risk of infection virus in indoor environments. This was based on 10 years of data gathered from influenza-like ...

the 2009 Pandemic Influenza A (H1N1) Virus Hospita. Hospitalized Patients with 2009 H1N1 Influenza in the United States, April–June 2009. NEJM.  Abstract  
submitted by kickingbird at Oct, 15, 2009 from NEJM (via http://content.nejm.org/cgi/content/full/NEJMoa0906695)
Background During the spring of 2009, a pandemic influenza A (H1N1) virus emerged and spread globally. We describe the clinical characteristics of the patients who were hospitalized with 2009 H1N1 influenza ...

Seema Jain. Underlying conditions linked to more severe cases of influenza A (H1N1). The New England Journal of Medicine.  Abstract  
submitted by kickingbird at Oct, 13, 2009 from The New England Journal of Medicine (via http://infectiousdiseasenews.com/article/44444.aspx#)
The 2009 H1N1 influenza caused severe illness requiring hospitalization during the outbreak’s peak in the Northern Hemisphere last spring and was a burden on ICUs in the Southern Hemisphere during their ...

. Treatment with extracorporeal membrane oxygenation may be required for many patients with influenza A (H1N1). JAMA. 2009;302(17)..  Abstract  
submitted by kickingbird at Oct, 13, 2009 from JAMA. 2009;302(17). (via http://www.infectiousdiseasenews.com/article/44496.aspx#)
One-third of young adult patients in Australia and New Zealand may have received extracorporeal membrane oxygenation to treat respiratory failure associated with influenza A (H1N1), according to findings ...

US CDC. Bacterial Coinfections in Lung Tissue Specimens from Fatal Cases of 2009 Pandemic Influenza A (H1N1) --- United States, May--August 2009. MMWR Morb Mortal Wkly Rep 2009; 58 (early release).  Abstract  
submitted by kickingbird at Oct, 1, 2009 from MMWR Morb Mortal Wkly Rep 2009; 58 (early release) (via http://www.cdc.gov/mmwr/preview/mmwrhtml/mm58e0929a1.htm?s_c)
In previous influenza pandemics, studies of autopsy specimens have shown that most deaths attributed to influenza A virus infection occurred concurrently with bacterial pneumonia (1), but such evidence ...

MMWR. Oseltamivir-Resistant Novel Influenza A (H1N1) Virus Infection in Two Immunosuppressed Patients --- Seattle, Washington, 2009. MMWR Dispatch, 14 Aug 2009 / 58 (Dispatch); 1-4.  Abstract  
submitted by kickingbird at Aug, 16, 2009 from MMWR Dispatch, 14 Aug 2009 / 58 (Dispatch); 1-4 (via http://www.cdc.gov/mmwr/preview/mmwrhtml/mm58d0814a1.htm?s_c)
Novel influenza A (H1N1) virus infection continues to cause illness and death among persons worldwide. Immunosuppressed patients with influenza virus infection can shed virus for prolonged periods, increasing ...

Amesh A. Adalja. Zanamivir Resistance in Influenza. CBN.  Abstract  
submitted by kickingbird at Aug, 14, 2009 from CBN (via http://www.upmc-cbn.org/report_archive/2009/08_August_2009/c)
Antiviral therapy against influenza always has been plagued by the development of resistance. Unfortunately, as medical management of influenza relies increasingly on antiviral therapy, drug resistance ...

Danishuddin M, Khan AU.. Phylogenetic Analysis of the Neuraminidase Gene Reveals that the H5N1 Strains Prevalent in Chickens During 2006 Bird Flu Outbreaks in Two Regions of Maharashtra, India Are Genetically Different. Genomics Proteomics Bioinformatics. 2009 Jun;7(1-2.  Abstract  
submitted by kickingbird at Jul, 16, 2009 from Genomics Proteomics Bioinformatics. 2009 Jun;7(1-2 (via http://www.ncbi.nlm.nih.gov/pubmed/19591792?ordinalpos=39&it)
In February 2006, two outbreaks of highly pathogenic avian influenza A virus subtype H5N1 occurred in chickens in two neighboring districts (first in Nandurbar and second in Jalgaon) of Maharashtra, India, ...

van Zoelen MA, van der Sluijs KF, Achouiti A, Flor. Receptor for advanced glycation end products is detrimental during influenza A virus pneumonia. Virology. 2009 Jul 8.  Abstract  
submitted by kickingbird at Jul, 16, 2009 from Virology. 2009 Jul 8 (via http://www.ncbi.nlm.nih.gov/pubmed/19592063?ordinalpos=35&it)
Pneumonia caused by influenza A virus (IAV) can have devastating effects, resulting in respiratory failure and death. The idea that a new influenza pandemic might occur in the near future has triggered ...

Lange E, Kalthoff D, Blohm U, Teifke JP, Breithaup. Pathogenesis and transmission of the novel swine origin influenza virus A/H1N1 after experimental infection of pigs. J Gen Virol. 2009 Jul 10..  Abstract  
submitted by kickingbird at Jul, 16, 2009 from J Gen Virol. 2009 Jul 10. (via http://www.ncbi.nlm.nih.gov/pubmed/19592456?ordinalpos=33&it)
Influenza virus A/H1N1n currently causing a pandemic contains gene segments with ancestors in North American and Eurasian swine lineages. To get insights into virus replication dynamics, clinical symptoms ...

Ilyinskii PO, Schmidt T, Lukashev D, Meriin AB, Th. Importance of mRNA Secondary Structural Elements for the Expression of Influenza Virus Genes. OMICS. 2009 Jul 13..  Abstract  
submitted by kickingbird at Jul, 16, 2009 from OMICS. 2009 Jul 13. (via http://www.ncbi.nlm.nih.gov/pubmed/19594376?ordinalpos=28&it)
Development of novel vaccines and therapeutics often requires efficient expression of recombinant viral proteins. Here we show that mutations in essential functional regions of conserved influenza proteins ...

Husain M, Harrod KS. Influenza A virus-induced caspase-3 cleaves the histone deacetylase 6 in infected epithelial cells. FEBS Lett. 2009 Jul 10.  Abstract  
submitted by kickingbird at Jul, 16, 2009 from FEBS Lett. 2009 Jul 10 (via http://www.ncbi.nlm.nih.gov/pubmed/19596000?ordinalpos=24&it)
Histone deacetylase 6 (HDAC6) is a multi-substrate cytoplasmic enzyme that regulates many important biological processes. Recently, some reports have implicated HDAC6 in viral infection. However, nothing ...

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