Zhu H, Wang D, Kelvin DJ, Li L, Zheng Z, Yoon SW,. Infectivity, Transmission, and Pathology of Human-Isolated H7N9 Influenza Virus in Ferrets and Pigs. Science. 2013 Jul 12;341(6142):183-186.. Abstract
submitted by kickingbird at Jul, 15, 2013 from Science. 2013 Jul 12;341(6142):183-186. (via http://www.ncbi.nlm.nih.gov/pubmed/23704376)
The emergence of the H7N9 influenza virus in humans in Eastern China has raised concerns that a new influenza pandemic could occur. Here, we used a ferret model to evaluate the infectivity and transmissibility ... Zhu W, Yang S, Guo Y, Yang L, Bai T, Yu Z, Li X, L. Imported pigs may have introduced the first classical swine influenza viruses into Mainland China. Infect Genet Evol. 2013 Jul;17:142-6.. Abstract
submitted by kickingbird at Jul, 15, 2013 from Infect Genet Evol. 2013 Jul;17:142-6. (via http://www.ncbi.nlm.nih.gov/pubmed/23567818)
Abstract
OBJECTIVES:
The first classical swine influenza A H1N1 viruses were isolated in Mainland China in 1991. To aid surveillance of swine influenza viruses as part of pandemic preparedness, we ... WATANABE T, Tisoncik-Go J, Tchitchek N, Watanabe S. 1918 Influenza virus hemagglutinin (HA) and the viral RNA polymerase complex enhance viral pathogenicity, but only HA induces aberrant host responses in mice. J Virol. 2013 May;87(9):5239-54. Abstract
submitted by kickingbird at Jul, 14, 2013 from J Virol. 2013 May;87(9):5239-54 (via http://www.ncbi.nlm.nih.gov/pubmed/23449804)
The 1918 pandemic influenza virus was the most devastating infectious agent in human history, causing fatal pneumonia and an estimated 20 to 50 million deaths worldwide. Previous studies indicated a prominent ... MASIC A, Pyo HM, Babiuk S, Zhou Y, et al. An eight-segment swine influenza virus harbouring H1 and H3 hemagglutinins is attenuated and protective against H1N1 and H3N2 subtypes in pigs. J Virol. 2013 Jul 10.. Abstract
submitted by kickingbird at Jul, 14, 2013 from J Virol. 2013 Jul 10. (via http://www.ncbi.nlm.nih.gov/pubmed/23843633)
Swine influenza virus (SIV) infections continue to cause production losses in the agricultural industry in addition to being a human public health concern. The primary method to control SIV is through ... ROBERTS KL, Leser GP, Ma C, Lamb RA, et al. The amphipathic helix of influenza A virus M2 protein is required for filamentous bud formation and scission of filamentous and spherical particles. J Virol. 2013 Jul 10. Abstract
submitted by kickingbird at Jul, 14, 2013 from J Virol. 2013 Jul 10 (via http://www.ncbi.nlm.nih.gov/pubmed/23843641)
Influenza virus assembles and buds at the infected-cell plasma membrane. This involves extrusion of the plasma membrane followed by scission of the bud, resulting in severing the nascent virion from its ... LONG JS, Howard WA, Nunez A, Moncorge O, et al. The effect of the PB2 mutation 627K on highly pathogenic H5N1 avian influenza virus is dependent on the virus lineage. J Virol. 2013 Jul 10.. Abstract
submitted by kickingbird at Jul, 14, 2013 from J Virol. 2013 Jul 10. (via http://www.ncbi.nlm.nih.gov/pubmed/23843645)
Clade 2.2 Eurasian lineage H5N1 highly pathogenic avian influenza viruses (HPAIV), were first detected in Qinghai Lake, China in 2005, and subsequently spread through Asia, Europe and Africa. Importantly, ... LANGLEY JM, Carmona Martinez A, Chatterjee A, Halp. Immunogenicity and Safety of an Inactivated Quadrivalent Influenza Vaccine Candidate: A Phase III Randomized Controlled Trial in Children. J Infect Dis. 2013 Jul 11. Abstract
submitted by kickingbird at Jul, 14, 2013 from J Infect Dis. 2013 Jul 11 (via http://www.ncbi.nlm.nih.gov/pubmed/23847058)
Background.?Mismatch between circulating influenza B viruses (Yamagata and Victoria lineages) and vaccine strains occurs frequently.Methods.?In a randomized controlled trial, immunogenicity and safety ... HE L, Zhao G, Zhong L, Liu Q, et al. Isolation and characterization of two H5N1 influenza viruses from swine in Jiangsu Province of China. Arch Virol. 2013 Jul 9. Abstract
submitted by kickingbird at Jul, 14, 2013 from Arch Virol. 2013 Jul 9 (via http://www.ncbi.nlm.nih.gov/pubmed/23836394)
Pigs are susceptible to infection with both human and avian influenza A viruses and are considered intermediate hosts that facilitate virus reassortment. Although H5N1 virus has spread to a wide range ... Scott Epperson, etc.,al. Human Infections With Influenza A(H3N2) Variant Virus in the United States, 2011–2012. Clin Infect Dis. (2013) 57 (suppl 1): S4-S11 doi:. Abstract
submitted by kickingbird at Jul, 12, 2013 from Clin Infect Dis. (2013) 57 (suppl 1): S4-S11 doi: (via http://cid.oxfordjournals.org/content/57/suppl_1/S4.abstract)
Background.During August 2011–April 2012, 13 human infections with influenza A(H3N2) variant (H3N2v) virus were identified in the United States; 8 occurred in the prior 2 years. This virus differs from ... Karen K. Wong, etc.,al. Transmissibility of Variant Influenza From Swine to Humans: A Modeling Approach. Clin Infect Dis. (2013) 57 (suppl 1): S16-S22 doi. Abstract
submitted by kickingbird at Jul, 12, 2013 from Clin Infect Dis. (2013) 57 (suppl 1): S16-S22 doi (via http://cid.oxfordjournals.org/content/57/suppl_1/S16.abstrac)
Background.Respiratory illness was reported among humans and swine at an agricultural fair in 2011; 3 human infections with an influenza A(H3N2) variant (H3N2v) virus were confirmed. Using epidemiologic ... Manoj Gambhir,etc.,al. Multiple Contributory Factors to the Age Distribution of Disease Cases: A Modeling Study in the Context of Influenza A(H3N2v). Clin Infect Dis. (2013) 57 (suppl 1): S23-S27 doi. Abstract
submitted by kickingbird at Jul, 12, 2013 from Clin Infect Dis. (2013) 57 (suppl 1): S23-S27 doi (via http://cid.oxfordjournals.org/content/57/suppl_1/S23.abstrac)
Background. In late 2011 and early 2012, 13 cases of human influenza resulted from infection with a novel triple reassortant swine-origin influenza virus, influenza A (H3N2) variant. This variant was notable ... JA Belser, etc.,al. Pathogenesis and transmission of avian influenza A (H7N9) virus in ferrets and mice. Nature Year published: (2013) DOI: doi:10.1038/nat. Abstract
submitted by kickingbird at Jul, 12, 2013 from Nature Year published: (2013) DOI: doi:10.1038/nat (via http://www.nature.com/nature/journal/vaop/ncurrent/full/natu)
On 29 March 2013, the Chinese Center for Disease Control and Prevention confirmed the first reported case of human infection with an avian influenza A(H7N9) virus1. The recent human infections with H7N9 ... Yinhua Huang, etc.,al. The duck genome and transcriptome provide insight into an avian influenza virus reservoir species. Nature Genetics 45, 776–783 (2013). Abstract
submitted by kickingbird at Jul, 11, 2013 from Nature Genetics 45, 776–783 (2013) (via http://www.nature.com/ng/journal/v45/n7/full/ng.2657.html)
The duck (Anas platyrhynchos) is one of the principal natural hosts of influenza A viruses. We present the duck genome sequence and perform deep transcriptome analyses to investigate immune-related genes. ... Andrew B. Reeves, etc.,al. GENOMIC ANALYSIS OF AVIAN INFLUENZA VIRUSES FROM WATERFOWL IN WESTERN ALASKA, USA. jwildlifedis July 1, 2013 vol. 49 no. 3 600-61. Abstract
submitted by kickingbird at Jul, 11, 2013 from jwildlifedis July 1, 2013 vol. 49 no. 3 600-61 (via http://www.jwildlifedis.org/content/49/3/600.full)
The Yukon-Kuskokwim Delta (Y-K Delta) in western Alaska is an immense and important breeding ground for waterfowl. Migratory birds from the Pacific Americas, Central Pacific, and East Asian-Australasian ... KREIJTZ JH, Kroeze EV, Stittelaar KJ, de Waal L, e. Low pathogenic avian influenza A(H7N9) virus causes high mortality in ferrets upon intratracheal challenge: A model to study intervention strategies. Vaccine. 2013 Jun 28. pii: S0264-410X(13)00880. Abstract
submitted by kickingbird at Jul, 9, 2013 from Vaccine. 2013 Jun 28. pii: S0264-410X(13)00880 (via http://www.ncbi.nlm.nih.gov/pubmed/23816392)
Infections with low pathogenic avian influenza (LPAI) A(H7N9) viruses have caused more than 100 hospitalized human cases of severe influenza in China since February 2013 with a case fatality rate exceeding ... SALATHE M, Freifeld CC, Mekaru SR, Tomasulo AF, et. Influenza A (H7N9) and the Importance of Digital Epidemiology. N Engl J Med. 2013 Jul 3. Abstract
submitted by kickingbird at Jul, 9, 2013 from N Engl J Med. 2013 Jul 3 (via http://www.nejm.org/doi/full/10.1056/NEJMp1307752)
On March 31, 2013, Chinese health officials notified the World Health Organization of three cases of human infection with novel influenza A (H7N9). Since then, 132 people have been infected, 37 of them ... LI Q, Qi J, Wu Y, Kiyota H, et al. Functional and structural analysis of influenza neuraminidase N3 offers further insight into the mechanisms of oseltamivir-resistance. J Virol. 2013 Jul 3. Abstract
submitted by kickingbird at Jul, 9, 2013 from J Virol. 2013 Jul 3 (via http://www.ncbi.nlm.nih.gov/pubmed/23824808)
The influenza neuraminidase H274Y substitution is a highly prevalent amino acid substitution associated with resistance to the most heavily used influenza drug, oseltamivir. Previous structural studies ... MAGADAN JG, Khurana S, Das SR, Frank GM, et al. Influenza A Virus Hemagglutinin Trimerization Completes Monomer Folding and Antigenicity. J Virol. 2013 Jul 3. Abstract
submitted by kickingbird at Jul, 9, 2013 from J Virol. 2013 Jul 3 (via http://www.ncbi.nlm.nih.gov/pubmed/23824811)
Influenza A virus (IAV) remains an important human pathogen largely due to antigenic drift: the rapid emergence of antibody escape mutants which precludes durable vaccination. The most potent neutralizing ... LOVING CL, Lager KM, Vincent AL, Brockmeier SL, et. Efficacy of inactivated and live-attenuated influenza virus vaccines in pigs against infection and transmission of emerging H3N2 similar to the 2011-2012 H3N2v. J Virol. 2013 Jul 3. Abstract
submitted by kickingbird at Jul, 9, 2013 from J Virol. 2013 Jul 3 (via http://www.ncbi.nlm.nih.gov/pubmed/23824815)
Vaccines provide a primary means to limit disease but may not be effective at blocking infection and pathogen transmission. The objective of the current study was to evaluate the efficacy of commercial ... LI Y, Bostick DL, Sullivan CB, Myers JL, et al. Single Hemagglutinin Mutations that Alter Both Antigenicity and Receptor Binding Avidity Influence Influenza Virus Antigenic Clustering. J Virol. 2013 Jul 3.. Abstract
submitted by kickingbird at Jul, 9, 2013 from J Virol. 2013 Jul 3. (via http://www.ncbi.nlm.nih.gov/pubmed/23824816)
The hemagglutination-inhibition (HAI) assay is the primary measurement used for identifying antigenically novel influenza strains. HAI assays measure the amount of reference sera required to prevent virus ... 5584 items, 20/Page, Page[208/280][|<<] [|<] [201] [202] [203] [204] [205] [206] [207] [208] [209] [210] [>|] [>>|] |
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