Gao R, Du N, Liu D, Zhou J, et al.. Oseltamivir inhibits both viral entry and release but enhances apoptosis of cells infected with influenza A H1N1. Biochem Biophys Res Commun 2013 Jan 17. pii: S0006. Abstract
submitted by kickingbird at Jan, 30, 2013 from Biochem Biophys Res Commun 2013 Jan 17. pii: S0006 (via http://www.ncbi.nlm.nih.gov/m/pubmed/23333739/)
Oseltamivir (Tamiflu) has been shown to be effective as a treatment and chemoprophylaxis for influenza virus infections. However, the safety consideration of oseltamivir should not be overlooked because ... Siboonnan N, Wiriyarat W, Boonarkart C, Chakritbud. A serine-to-asparagine mutation at position 314 of H5N1 avian influenza virus NP is a temperature-sensitive mutation that interferes with nuclear localization of NP. Arch Virol 2013.. Abstract
submitted by kickingbird at Jan, 25, 2013 from Arch Virol 2013. (via http://www.ncbi.nlm.nih.gov/m/pubmed/23307364/)
We have generated a temperature-sensitive (ts) mutant from a human isolate of the H5N1 avian influenza virus by classical adaptation in cell culture. After 20 passages at low temperature, the virus showed ... Jegaskanda S, Job ER, Kramski M, Laurie K, et al.. Cross-Reactive Influenza-Specific Antibody-Dependent Cellular Cytotoxicity Antibodies in the Absence of Neutralizing Antibodies.. J Immunol 2013.. Abstract
submitted by kickingbird at Jan, 25, 2013 from J Immunol 2013. (via http://www.ncbi.nlm.nih.gov/m/pubmed/23319732/)
Abstract
A better understanding of immunity to influenza virus is needed to generate cross-protective vaccines. Engagement of Ab-dependent cellular cytotoxicity (ADCC) Abs by NK cells leads to killing ... Zhang AJ, To KK, Li C, Lau CC, et al.. Leptin mediates the pathogenesis of severe influenza A(H1N1)pdm09 associated with cytokine dysregulation is preventable by anti-leptin antibody in diet-induced obese mice.. J Infect Dis 2013.. Abstract
submitted by kickingbird at Jan, 25, 2013 from J Infect Dis 2013. (via http://www.ncbi.nlm.nih.gov/m/pubmed/23325916/)
Abstract
Background.?Obesity is associated with a high circulating leptin level and severe influenza A(H1N1)pdm09 infection. The mechanism for severe lung injury in obese patients and the specific treatment ... Zimmermann U, Gavazzi G, Richard P, Eymin C, et al. Immunogenicity and safety of a booster dose of diphtheria, tetanus, acellular pertussis and inactivated poliomyelitis vaccine (Tdap-IPV; Repevax((R))) administered concomitantly versus non-concomitant. Vaccine 2013 Jan 10. pii: S0264-410X(13)00010. Abstract
submitted by kickingbird at Jan, 25, 2013 from Vaccine 2013 Jan 10. pii: S0264-410X(13)00010 (via http://www.ncbi.nlm.nih.gov/m/pubmed/23313654/)
Abstract
BACKGROUND: Annual influenza vaccination provides an opportunity to administer a booster dose of diphtheria, tetanus, acellular pertussis and inactivated poliomyelitis vaccine (Tdap-IPV) to the ... Chertow DS, Memoli MJ. Bacterial coinfection in influenza: a grand rounds review. JAMA 2013;309:275-82. Abstract
submitted by kickingbird at Jan, 25, 2013 from JAMA 2013;309:275-82 (via http://www.ncbi.nlm.nih.gov/m/pubmed/23321766/)
Abstract
Bacterial coinfection complicated nearly all influenza deaths in the 1918 influenza pandemic and up to 34% of 2009 pandemic influenza A(H1N1) infections managed in intensive care units worldwide. ... Haberg SE, Trogstad L, Gunnes N, Wilcox AJ, et al. Risk of Fetal Death after Pandemic Influenza Virus Infection or Vaccination.. N Engl J Med 2013. Abstract
submitted by kickingbird at Jan, 25, 2013 from N Engl J Med 2013 (via http://www.ncbi.nlm.nih.gov/m/pubmed/23323868/)
Abstract
BACKGROUND: During the 2009 influenza A (H1N1) pandemic, pregnant women were at risk for severe influenza illness. This concern was complicated by questions about vaccine safety in pregnant ... Rykkvin R, Kilander A, Dudman SG, Hungnes O.. Within-patient emergence of the influenza A(H1N1)pdm09 HA1 222G variant and clear association with severe disease, Norway. Euro Surveill. 2013;18(3):pii=20369. Abstract
submitted by kickingbird at Jan, 18, 2013 from Euro Surveill. 2013;18(3):pii=20369 (via http://www.eurosurveillance.org:80/ViewArticle.aspx?ArticleI)
The association between a particular mutation in the HA1 subunit of the influenza virus haemagglutinin, D222G, and severe and fatal disease in cases of influenza A(H1N1)pdm09 in Norway during the 2009 ... CDC and other experts. Early Estimates of Seasonal Influenza Vaccine Effectiveness — United States, January 2013. MMWR Weekly. Abstract
submitted by kickingbird at Jan, 12, 2013 from MMWR Weekly (via http://www.cdc.gov/mmwr/preview/mmwrhtml/mm62e0111a1.htm?s_c)
In the United States, annual vaccination against seasonal influenza is recommended for all persons aged ≥6 months (1). Each season since 2004–05, CDC has estimated the effectiveness of seasonal influenza ... Martin C.W. Chan, etc.,al. A ´pre-seasonal´ hospital outbreak of influenza pneumonia caused by the drift variant A/Victoria/361/2011-like H3N2 viruses, Hong Kong, 2011. Journal of Clinical Virology. Abstract
submitted by kickingbird at Jan, 12, 2013 from Journal of Clinical Virology (via http://www.sciencedirect.com/science/article/pii/S1386653212)
Abstract
Background
Beginning from late 2011 and early 2012, increasing circulation of antigenically drifted influenza A/Victoria/361/2011-like H3N2 viruses within genotype 3 of the A/Victoria/208/2009 ... DESMET EA, Bussey KA, Stone R, Takimoto T, et al. Identification of the N-terminal domain of influenza PA responsible for the suppression of host protein synthesis. J Virol. 2013. Abstract
submitted by kickingbird at Jan, 6, 2013 from J Virol. 2013 (via http://www.ncbi.nlm.nih.gov/pubmed/23283952)
Cellular protein synthesis is suppressed during influenza virus infection, allowing for preferential production of viral proteins. To explore the impact of polymerase subunits on protein synthesis, we ... JIANG W, Wang Q, Chen S, Gao S, et al.. Influenza A virus NS1 induces G0/G1 cell cycle arrest by inhibiting the expression and activity of RhoA protein. J Virol. 2013.. Abstract
submitted by kickingbird at Jan, 6, 2013 from J Virol. 2013. (via http://www.ncbi.nlm.nih.gov/pubmed/23283961)
Influenza A virus is an important pathogenic virus known to induce host cell cycle arrest in G0/G1 phase and create beneficial conditions for viral replication. However, how the virus achieves arrest remains ... TILLIB SV, Ivanova TI, Vasilev LA, Rutovskaya MV,. Formatted single-domain antibodies can protect mice against infection with influenza virus (H5N2). Antiviral Res. 2012 Dec 25. pii: S0166-3542(12)002. Abstract
submitted by kickingbird at Jan, 6, 2013 from Antiviral Res. 2012 Dec 25. pii: S0166-3542(12)002 (via http://www.ncbi.nlm.nih.gov/pubmed/23274623)
This work continues a series of recently published studies that employ recombinant single-domain antibody (sdAb, or nanobody?) generation technologies to battle viruses by a passive immunization approach. ... LEANG SK, Deng YM, Shaw R, Caldwell N, et al.. Influenza antiviral resistance in the Asia-Pacific region during 2011. Antiviral Res. 2012 Dec 25. pii: S0166-3542(12)002. Abstract
submitted by kickingbird at Jan, 6, 2013 from Antiviral Res. 2012 Dec 25. pii: S0166-3542(12)002 (via http://www.ncbi.nlm.nih.gov/pubmed/23274624)
Despite greater than 99% of influenza A viruses circulating in the Asia-Pacific region being resistant to the adamantane antiviral drugs in 2011, the large majority of influenza A (>97%) and B strains ... HU J, Hu Z, Song Q, Gu M, et al. The PA gene-mediated lethal dissemination and excessive innate immune response contribute to the high virulence of H5N1 avian influenza virus in mice. J Virol. 2012. Abstract
submitted by kickingbird at Jan, 2, 2013 from J Virol. 2012 (via http://www.ncbi.nlm.nih.gov/pubmed/23255810)
Highly pathogenic H5N1 influenza A virus remains a substantial threat to public health. To understand the molecular basis and host mechanism for the high virulence of H5N1 viruses in mammals, we compared ... GARG S, Moore Z, Lee N, McKenna J, et al.. A Cluster of Patients Infected with I221V Influenza B Virus Variants with Reduced Oseltamivir Susceptibility--North Carolina and South Carolina, 2010-2011. J Infect Dis. 2012. Abstract
submitted by kickingbird at Jan, 2, 2013 from J Infect Dis. 2012 (via http://www.ncbi.nlm.nih.gov/pubmed/23242536)
Background.?During 2010-2011, influenza B viruses with a novel neuraminidase substitution, denoted I221V, (B/I221V) associated with reduced in vitro oseltamivir susceptibility were detected in North Carolina ... TAKAYAMA I, Nakauchi M, Fujisaki S, Odagiri T, et. Rapid detection of the S247N neuraminidase mutation in influenza A(H1N1)pdm09 virus by one-step duplex RT-PCR assay. J Virol Methods. 2012 Dec 19. pii: S0166-0934(12)0. Abstract
submitted by kickingbird at Jan, 2, 2013 from J Virol Methods. 2012 Dec 19. pii: S0166-0934(12)0 (via http://www.ncbi.nlm.nih.gov/pubmed/23261798)
Neuraminidase inhibitors, especially oseltamivir, have been used worldwide for the prophylaxis or treatment of pandemic influenza H1N1 2009 (A(H1N1)pdm09) viruses. The most commonly detected oseltamivir-resistant ... NGUYEN TT, Kwon HJ, Kim IH, Hong SM, et al. Multiplex nested RT-PCR for detecting avian influenza virus, infectious bronchitis virus and Newcastle disease virus. J Virol Methods. 2012 Dec 19. pii: S0166-0934(12)0. Abstract
submitted by kickingbird at Jan, 2, 2013 from J Virol Methods. 2012 Dec 19. pii: S0166-0934(12)0 (via http://www.ncbi.nlm.nih.gov/pubmed/23261801)
In this study, multiplex nested RT-PCR (mnRT-PCR) was applied to simultaneous detect multiplex PCR with the higher sensitivity of nested PCR that is required for avian influenza, infectious bronchitis ... SUN Y, Tan Y, Wei K, Sun H, et al. Amino acid 316 of hemagglutinin and the neuraminidase stalk length influence virulence of H9N2 influenza virus in chickens and mice. J Virol. 2012. Abstract
submitted by kickingbird at Jan, 2, 2013 from J Virol. 2012 (via http://www.ncbi.nlm.nih.gov/pubmed/23269805)
H9N2 influenza viruses with an A316S substitution in hemagglutinin (HA) and a shorter neuraminidase (NA) stalk have become predominant in China. The A316S was shown to increase HA cleavage efficiency when ... WANG D, Sleeman K, Huang W, Nguyen HT, et al. Neuraminidase Inhibitor Susceptibility Testing of Influenza Type B Viruses in China during 2010 and 2011 Identifies Viruses with Reduced Susceptibility to Oseltamivir and Zanamivir. Antiviral Res. 2012 Dec 22. pii: S0166-3542(12)002. Abstract
submitted by kickingbird at Jan, 2, 2013 from Antiviral Res. 2012 Dec 22. pii: S0166-3542(12)002 (via http://www.ncbi.nlm.nih.gov/pubmed/23267831)
Influenza type B viruses are responsible for substantial morbidity and mortality in humans. Antiviral drugs are an important supplement to vaccination for reducing the public health impact of influenza ... 5328 items, 20/Page, Page[202/267][|<<] [|<] [201] [202] [203] [204] [205] [206] [207] [208] [209] [210] [>|] [>>|] |
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