Bernadeta Dadonaite, etc.,al. [preprint]Defining the molecular interaction between influenza hemagglutinin and MHC-II. https://doi.org/10.64898/2026.07.17.738765. Abstract
submitted by kickingbird at 9 days ago from https://doi.org/10.64898/2026.07.17.738765 (via https://www.biorxiv.org/content/10.64898/2026.07.17.738765v1)
The hemagglutinin (HA) of some influenza viruses can interact with major histocompatibility complex class II (MHC-II), but how these proteins interact is unclear. Here we demonstrate that diverse H5 HAs ... Heather M. Machkovech, etc.,al. [preprint]Evolutionary constraints limit additional mammalian adaptation of bovine-derived H5N1 influenza viruses in ferrets. https://doi.org/10.64898/2026.07.20.739655. Abstract
submitted by kickingbird at 9 days ago from https://doi.org/10.64898/2026.07.20.739655 (via https://www.biorxiv.org/content/10.64898/2026.07.20.739655v1)
The outbreak of clade 2.3.4.4b H5N1 viruses among U.S. dairy cattle has raised concerns that sustained circulation among agricultural mammals could facilitate viral adaptation toward efficient human transmission. ... Hernandez-Gonzalez KM, Carranza-Aranda AS, Mu?oz-V. Molecular Characterization of Influenza A(H3N2) Hemagglutinin Variants Circulating in Western Mexico, 2022. International Journal of Molecular Sciences. 2026;. Abstract
submitted by kickingbird at 10 days ago from International Journal of Molecular Sciences. 2026; (via https://www.mdpi.com/1422-0067/27/15/6833)
Influenza A(H3N2) remains a significant public health threat due to its rapid antigenic drift, which often compromises vaccine effectiveness. This study characterized the molecular and epidemiological ... Volkhin IA, Dashian MA, Lukashev AN, Shipulin GA,. Assessment of Quantitative Genetic Distances Supports the Separation of H17N10 and H18N11 Subtypes of Influenza A Virus into a Distinct Species. Viruses. 2026; 18(8):838. Abstract
submitted by kickingbird at 11 days ago from Viruses. 2026; 18(8):838 (via https://www.mdpi.com/1999-4915/18/8/838)
The taxonomic status of the H17N10 and H18N11 influenza A viruses isolated from bats remains unclear due to the absence of quantitative classification criteria at this taxonomic level. A total of 3328 ... Li Y, Song X, Gao T, Wang G, Wei H, Wang J, Jiang. Genetic and Pathogenicity Studies of Avian Influenza (H9N2) Virus Isolated from Chickens in Jiangsu Province, China, in 2025. Microorganisms. 2026; 14(8):1667. Abstract
submitted by kickingbird at 11 days ago from Microorganisms. 2026; 14(8):1667 (via https://www.mdpi.com/2076-2607/14/8/1667)
In this study, one H9N2 subtype avian influenza virus (AIV) was isolated in Jiangsu Province, China, in March 2025. According to phylogenetic analysis, the HA gene fragment of the H9N2 isolate was classified ... Vidanovi? D, Maleti? J, ?ekler M, Te?ovi? B, Vasko. Complete coding sequence of influenza A virus subtype H1N3 from guinea fowl in Republic of Serbia. Microbiol Resour Announc. 2026 Jul 29:e0021326. Abstract
submitted by kickingbird at 12 days ago from Microbiol Resour Announc. 2026 Jul 29:e0021326 (via https://journals.asm.org/doi/10.1128/mra.00213-26)
Here, we report the complete coding sequence of the avian influenza A virus subtype H1N3 from guinea fowl [A/Guinea fowl/Serbia/Vinca_household/2025(H1N3)] obtained on the Oxford Nanopore Technologies ... Ksenia Sukhova, etc.,al. [preprint]Mutations in severe human H5N1 cases facilitate evasion from human mucus and antivirals. https://doi.org/10.64898/2026.07.28.740943. Abstract
submitted by kickingbird at 12 days ago from https://doi.org/10.64898/2026.07.28.740943 (via https://www.biorxiv.org/content/10.64898/2026.07.28.740943v1)
In late 2024, two individuals in Canada and the United States were treated in intensive care for acute respiratory distress caused by infection with the avian Influenza A Virus H5N1 2.3.4.4b genotype D1.1. ... Taylor Pursell, etc.,al. [preprint]H5N1 influenza binding and cell entry via human class II MHC, and blocking by cross-reactive antibodies. https://doi.org/10.64898/2026.07.22.739677. Abstract
submitted by kickingbird at 12 days ago from https://doi.org/10.64898/2026.07.22.739677 (via https://www.biorxiv.org/content/10.64898/2026.07.22.739677v1)
Highly pathogenic avian influenza (HPAI) H5N1 clade 2.3.4.4b viruses are currently responsible for a multi-species outbreak affecting wild birds, poultry, numerous mammalian species, and humans. Influenza ... Yunfei Wang, Fabiola Vacca, Wes Rountree, Kevin Wi. [preprint]Characterization of Influenza A HA and NA Subtypes Using Protein Sequences. https://doi.org/10.64898/2026.07.22.740123. Abstract
submitted by kickingbird at 12 days ago from https://doi.org/10.64898/2026.07.22.740123 (via https://www.biorxiv.org/content/10.64898/2026.07.22.740123v1)
Motivation Influenza is an infectious disease associated with excess human deaths. For influenza A virus (IAV), the surface antigens hemagglutinin (HA) and neuraminidase (NA) define the specific subtype. ... Laura Mojsiejczuk, etc.,al. [preprint]Flu Mutation Explorer: an Interactive Platform for Mapping Host Adaptation Mutations in Influenza A Viruses. https://doi.org/10.64898/2026.07.22.740012. Abstract
submitted by kickingbird at 12 days ago from https://doi.org/10.64898/2026.07.22.740012 (via https://www.biorxiv.org/content/10.64898/2026.07.22.740012v1)
A rapid expansion of influenza A virus (IAV) genome sequencing has transformed global surveillance but has also created major challenges for interpreting the biological significance of viral mutations, ... Lara S. U. Schwab, etc.,al. [preprint]Epistasis facilitates the long-term antigenic evolution of the influenza B virus hemagglutinin. https://doi.org/10.64898/2026.07.22.739994. Abstract
submitted by kickingbird at 12 days ago from https://doi.org/10.64898/2026.07.22.739994 (via https://www.biorxiv.org/content/10.64898/2026.07.22.739994v1)
The antigenic drift of viral glycoproteins must be balanced by purifying selection pressure to maintain functionality. Understanding these evolutionary processes is key to predicting and combating viral ... Ji J, Lin Y, Zhu Z, Yue K, Zhang Y, Zhang W, Lei B. Immunoinformatics Design of a Broad-Spectrum Multi-Epitope Vaccine Targeting HA2 and M1 of H9N2 AIV. Microorganisms. 2026; 14(8):1617. Abstract
submitted by kickingbird at 12 days ago from Microorganisms. 2026; 14(8):1617 (via https://www.mdpi.com/2076-2607/14/8/1617)
H9N2 avian influenza virus (AIV) continues to mutate, leading to immunosuppression and secondary infections in poultry. Traditional inactivated vaccines mainly induce humoral immunity and have limited ... Thayse Bruggemann, etc.,al. Phospholipid Phosphatase 6 (PLPP6) protects against influenza A virus infection in mice. The Journal of Immunology. Abstract
submitted by kickingbird at 12 days ago from The Journal of Immunology (via https://academic.oup.com/jimmunol/article/215/Supplement_1/v)
IntroductionPhospholipid phosphatase 6 (PLPP6) is a membrane-associated enzyme that regulates polyisoprenoid diphosphate signaling in cell activation. In response to inflammatory stimuli, PLPP6 converts ... Sean A Nelson, etc.,al. Distinct kinetic features of innate and adaptive responses in influenza A versus influenza B–infected mice. The Journal of Immunology. Abstract
submitted by kickingbird at 12 days ago from The Journal of Immunology (via https://academic.oup.com/jimmunol/article/215/7/vkag196/8745)
Influenza B infection is an important source of morbidity and mortality, especially in vulnerable populations such as children. Improved vaccines and antiviral therapeutics are hindered by gaps in knowledge ... Guo Luo, Emmanuel Mignot, Jing Zhang. Immunity to influenza B and cross-reactivity to Pandemrix/pH1N1 in narcolepsy. The Journal of Immunology. Abstract
submitted by kickingbird at 12 days ago from The Journal of Immunology (via https://academic.oup.com/jimmunol/article/215/Supplement_1/v)
IntroductionNarcolepsy type 1 (NT1) is caused by 85-95% hypocretin (HCRT) neuron loss due to a combination of genetic and environmental risk factors and associated with DQA1*01:02/DQB1*06:02 (DQ0602, 98%) ... Amber Smith, etc.,al. Multivariate Host-Pathogen Interactions Driving Heterogeneous Response to Influenza. The Journal of Immunology. Abstract
submitted by kickingbird at 12 days ago from The Journal of Immunology (via https://academic.oup.com/jimmunol/article/215/Supplement_1/v)
IntroductionInfluenza infections differ greatly among individuals, with controlled human infection studies showing wide variation in viral load, immune activation, and symptom profiles. However, the biological ... Rafael Medina, etc.,al. Dysregulated host responses are associated with severe influenza A virus disease in individuals with arterial hypertension. The Journal of Immunology. Abstract
submitted by kickingbird at 12 days ago from The Journal of Immunology (via https://academic.oup.com/jimmunol/article/215/Supplement_1/v)
IntroductionInfluenza A virus (IV) infections cause seasonal epidemics, which remain a major cause of morbidity and mortality worldwide. Disease severity depends on virological and host factors including ... Shiteng Huang, etc.,al. Molecular epidemiological characteristics of H9N2 subtype avian influenza virus in the external environment of Western Zhejiang, China, 2014-2025. Front. Public Health. Abstract
submitted by kickingbird at 13 days ago from Front. Public Health (via https://www.frontiersin.org/journals/public-health/articles/)
Objective: To elucidate the epidemiological distribution patterns of avian influenza virus (AIV) in the external environment of western Zhejiang from 2014 to 2025, analyze the molecular epidemiological ... Bemis IG, Shittu I, Gomez JF, Fadaka EA, Perez S,. Seroprevalence of Influenza A(H5N1) Virus in Domestic Cats at Epicenter of Dairy Cattle Outbreaks, California, USA, 2024–2026. Emerg Infect Dis. 2026 Sep. Abstract
submitted by kickingbird at 13 days ago from Emerg Infect Dis. 2026 Sep (via https://wwwnc.cdc.gov/eid/article/32/9/26-0785_article)
We conducted a serologic study of domestic cats near the epicenter of the dairy cattle outbreaks of influenza A(H5N1) in California, USA. Three of the 12 cats sampled within 2 km of farms had neutralizing ... Lee, H., Shin, Y., Heo, J. Y., Yu, A., Park, J. H.. Porcine Airway Organoids Reveal Strain-Associated Replication and Epithelial Host Response Signatures of a Reassortant H1N1 Virus. Emerging Microbes & Infections. Abstract
submitted by kickingbird at 14 days ago from Emerging Microbes & Infections (via https://www.tandfonline.com/doi/full/10.1080/22221751.2026.2)
Pigs serve as mixing vessels for influenza A viruses, facilitating reassortment and the emergence of variants with zoonotic potential. Since the 2009 pandemic, human-origin influenza gene segments have ... 7052 items, 20/Page, Page[2/353][|<<] [|<] [1] [2] [3] [4] [5] [6] [7] [8] [9] [10] [>|] [>>|] |
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