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2019-5-22 10:03:27
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Russell AB, et al. Single-cell virus sequencing of influenza infections that trigger innate immunity. J Virol. 2019 May 8.  Abstract  
submitted by kickingbird at 10 days ago from J Virol. 2019 May 8 (via https://www.ncbi.nlm.nih.gov/pubmed/31068418)
Influenza-infected cells vary widely in their expression of viral genes, and only occasionally activate innate immunity. Here we develop a new method to assess how the genetic variation in viral populations ...

Muscatello DJ, Leong RNF, Turner RM, Newall A. Rapid mapping of the spatial and temporal intensity of influenza. Eur J Clin Microbiol Infect Dis. 2019 May 8.  Abstract  
submitted by kickingbird at 10 days ago from Eur J Clin Microbiol Infect Dis. 2019 May 8 (via https://www.ncbi.nlm.nih.gov/pubmed/31069558)
Surveillance of influenza epidemics is a priority for risk assessment and pandemic preparedness, yet representation of their spatiotemporal intensity remains limited. Using the epidemic of influenza type ...

Mine J, et al. Genetics and pathogenicity of H5N6 highly pathogenic avian influenza viruses isolated from wild birds and a chicken in Japan during winter 2017~2018. Virology. 2019 May 2;533:1-11..  Abstract  
submitted by kickingbird at 10 days ago from Virology. 2019 May 2;533:1-11. (via https://www.ncbi.nlm.nih.gov/pubmed/31071540)
An H5N6 highly pathogenic avian influenza virus (HPAIV) outbreak occurred in poultry in Japan during January 2018, and H5N6 HPAIVs killed several wild birds in 3 prefectures during Winter 2017~2018. Time-measured ...

Scheibner D, et al. Virulence of three European highly pathogenic H7N1 and H7N7 avian influenza viruses in Pekin and Muscovy ducks. BMC Vet Res. 2019 May 10;15(1):142..  Abstract  
submitted by kickingbird at 10 days ago from BMC Vet Res. 2019 May 10;15(1):142. (via https://bmcvetres.biomedcentral.com/articles/10.1186/s12917-)
BACKGROUND: There is paucity of data on the virulence of highly pathogenic (HP) avian influenza viruses (AIV) H7 in ducks compared to HPAIV H5. Here, the virulence of HPAIV H7N1 (designated H7N1-FPV34 ...

Bonomo ME, Kim RY, Deem MW. Modular epitope binding predicts influenza quasispecies dominance and vaccine effectiveness: Application to 2018/19 season. Vaccine. 2019 May 3. pii: S0264-410X(19)30417-7..  Abstract  
submitted by kickingbird at 12 days ago from Vaccine. 2019 May 3. pii: S0264-410X(19)30417-7. (via https://www.sciencedirect.com/science/article/pii/S0264410X1)
The modular binding sites on the influenza A(H3N2) hemagglutinin protein are under significant pressure to acquire mutations in order to evade human antibody recognition. Analysis of these hemagglutinin ...

Bao J, et al. Decreased Frequencies of Th17 and Tc17 Cells in Patients Infected with Avian Influenza A (H7N9) Virus. J Immunol Res. 2019 Apr 2;2019:1418251.  Abstract  
submitted by kickingbird at 12 days ago from J Immunol Res. 2019 Apr 2;2019:1418251 (via https://www.hindawi.com/journals/jir/2019/1418251/)
The outbreak of avian influenza A (H7N9) virus infection, with a high mortality rate, has caused concern worldwide. Although interleukin-17- (IL-17-) secreting CD4+ T (Th17) and CD8+ T (Tc17) cells have ...

Fernandes-Matano L, et al. Analysis of influenza data generated by four epidemiological surveillance laboratories in Mexico, 2010~2016. Epidemiol Infect. 2019 Jan;147:e183..  Abstract  
submitted by kickingbird at 12 days ago from Epidemiol Infect. 2019 Jan;147:e183. (via https://www.cambridge.org/core/journals/epidemiology-and-inf)
The disease caused by the influenza virus is a global public health problem due to its high rates of morbidity and mortality. Thus, analysis of the information generated by epidemiological surveillance ...

Yip L, et al. Influenza virus RNA recovered from droplets and droplet nuclei emitted by adults in an acute care setting. J Occup Environ Hyg. 2019 May 3:1-8..  Abstract  
submitted by kickingbird at 14 days ago from J Occup Environ Hyg. 2019 May 3:1-8. (via https://www.tandfonline.com/doi/abs/10.1080/15459624.2019.15)
Transmission in hospital settings of seasonal influenza viruses and novel agents such as the Middle East respiratory syndrome coronavirus (MERS-CoV) is well-described but poorly understood. The characterization ...

Zhu L, et al. Influenza virus matrix protein M1 interacts with SLD5 to block host cell cycle. Cell Microbiol. 2019 May 3:e13038.  Abstract  
submitted by kickingbird at 14 days ago from Cell Microbiol. 2019 May 3:e13038 (via https://onlinelibrary.wiley.com/doi/abs/10.1111/cmi.13038)
Influenza virus matrix 1 protein (M1) is highly conserved and plays essential roles at many stages of virus life cycle. Here we used a yeast two-hybrid system to identify the host protein SLD5, a component ...

Zhang Y, Xu C, Zhang H, Liu GD, Xue C, Cao Y. Targeting Hemagglutinin: Approaches for Broad Protection against the Influenza A Virus. Viruses. 2019 Apr 30;11(5)..  Abstract  
submitted by kickingbird at 14 days ago from Viruses. 2019 Apr 30;11(5). (via https://www.mdpi.com/1999-4915/11/5/405)
Influenza A viruses are dynamically epidemic and genetically diverse. Due to the antigenic drift and shift of the virus, seasonal vaccines are required to be reformulated annually to match with current ...

Lee DH, et al. Intercontinental spread of Asian-origin H7 avian influenza viruses by captive bird trade in 1990´s. Infect Genet Evol. 2019 May 1..  Abstract  
submitted by kickingbird at 14 days ago from Infect Genet Evol. 2019 May 1. (via https://www.sciencedirect.com/science/article/pii/S156713481)
Wild bird migration and illegal trade of infected poultry, eggs, and poultry products have been associated with the spread of avian influenza viruses (AIV). During 1992-1996, H7N1 and H7N8 low pathogenic ...

Toh X, et al. Isolation and Characterization of Equine Influenza Virus (H3N8) from an Equine Influenza Outbreak in Malaysia in 2015. Transbound Emerg Dis. 2019 May 6.  Abstract  
submitted by kickingbird at 14 days ago from Transbound Emerg Dis. 2019 May 6 (via https://onlinelibrary.wiley.com/doi/abs/10.1111/tbed.13218)
Equine influenza is a major cause of respiratory infections in horses and can spread rapidly despite the availability of commercial vaccines. In this study, we carried out molecular characterization of ...

Bissinger T, et al. Semi-perfusion cultures of suspension MDCK cells enable high cell concentrations and efficient influenza A virus production. Vaccine. 2019 Apr 29..  Abstract  
submitted by kickingbird at May, 4, 2019 from Vaccine. 2019 Apr 29. (via https://www.sciencedirect.com/science/article/pii/S0264410X1)
Control and prevention of rapid influenza spread among humans depend on the availability of efficient and safe seasonal and pandemic vaccines, made primarily from inactivated influenza virus particles. ...

Zhu L, et al. Influenza virus matrix protein M1 interacts with SLD5 to block host cell cycle. Cell Microbiol. 2019 May 3:e13038.  Abstract  
submitted by kickingbird at May, 4, 2019 from Cell Microbiol. 2019 May 3:e13038 (via https://onlinelibrary.wiley.com/doi/abs/10.1111/cmi.13038)
Influenza virus matrix 1 protein (M1) is highly conserved and plays essential roles at many stages of virus life cycle. Here we used a yeast two-hybrid system to identify the host protein SLD5, a component ...

Takada K, et al. A humanized MDCK cell line for the efficient isolation and propagation of human influenza viruses. Nat Microbiol. 2019 Apr 29..  Abstract  
submitted by kickingbird at May, 2, 2019 from Nat Microbiol. 2019 Apr 29. (via https://www.nature.com/articles/s41564-019-0433-6)
Here, we developed hCK, a Madin-Darby canine kidney (MDCK) cell line that expresses high levels of human influenza virus receptors and low levels of avian virus receptors. hCK cells supported human A/H3N2 ...

Maslanka Figueroa S, et al. Influenza A virus mimetic nanoparticles trigger selective cell uptake. Proc Natl Acad Sci U S A. 2019 Apr 29..  Abstract  
submitted by kickingbird at May, 2, 2019 from Proc Natl Acad Sci U S A. 2019 Apr 29. (via https://www.pnas.org/content/early/2019/04/25/1902563116)
Poor target cell specificity is currently a major shortcoming of nanoparticles (NPs) used for biomedical applications. It causes significant material loss to off-target sites and poor availability at the ...

Soh YS, et al. Comprehensive mapping of adaptation of the avian influenza polymerase protein PB2 to humans. Elife. 2019 Apr 30;8.  Abstract  
submitted by kickingbird at May, 2, 2019 from Elife. 2019 Apr 30;8 (via https://elifesciences.org/articles/45079)
Viruses like influenza are infamous for their ability to adapt to new hosts. Retrospective studies of natural zoonoses and passaging in the lab have identified a modest number of host-adaptive mutations. ...

Hornick EE, et al. Dendritic cell NLRC4 regulates influenza A virus-specific CD4 T cell responses through FasL expression.. J Clin Invest. 2019 Apr 30;130.  Abstract  
submitted by kickingbird at May, 2, 2019 from J Clin Invest. 2019 Apr 30;130 (via https://www.jci.org/articles/view/124937)
Influenza A virus (IAV)-specific T cell responses are important correlates of protection during primary and subsequent infections. Generation and maintenance of robust IAV-specific T cell responses relies ...

Elbahesh H, Gerlach T, Saletti G, Rimmelzwaan G. Response Modifiers: Tweaking the Immune Response Against Influenza A Virus. Front Immunol. 2019 Apr 12;10:809.  Abstract  
submitted by kickingbird at May, 1, 2019 from Front Immunol. 2019 Apr 12;10:809 (via https://www.frontiersin.org/articles/10.3389/fimmu.2019.0080)
Despite causing pandemics and yearly epidemics that result in significant morbidity and mortality, our arsenal of options to treat influenza A virus (IAV) infections remains limited and is challenged by ...

Liu X, et al. Evidence for a novel mechanism of influenza A virus host adaption modulated by PB2-627. FEBS J. 2019 Apr 29..  Abstract  
submitted by kickingbird at May, 1, 2019 from FEBS J. 2019 Apr 29. (via https://febs.onlinelibrary.wiley.com/doi/abs/10.1111/febs.14)
Influenza virus cross-species transmission is restricted by the host, but viruses overcome this restriction by accumulating mutations which allow them to adapt to a new host. Among the many factors which ...

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