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2019-9-17 17:21:57
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Chen P, et al. A study of the relationship between human infection with avian influenza a (H5N6) and environmental avian influenza viruses in Fujian, China. BMC Infect Dis. 2019 Sep 2;19(1):762..  Abstract  
submitted by kickingbird at 12 days ago from BMC Infect Dis. 2019 Sep 2;19(1):762. (via https://bmcinfectdis.biomedcentral.com/articles/10.1186/s128)
BACKGROUND: Avian influenza A (H5N6) virus poses a great threat to the human health since it is capable to cross the species barrier and infect humans. Although human infections are believed to largely ...

Qiu Y, et al. Novel reassortant H7N2 originating from the H7N9 highly pathogenic avian influenza viruses in China, 2019. J Infect. 2019 Aug 29..  Abstract  
submitted by kickingbird at 14 days ago from J Infect. 2019 Aug 29. (via https://www.journalofinfection.com/article/S0163-4453(19)302)
In March 2013, the first human case of zoonotic H7N9 avian influenza virus (AIV) infection was reported in China. This virus has been circulating in domestic poultry in China while mutating to highly pathogenic ...

Li X, Chen J, Jin X, Hu J, Xie S, Dai Y, et al. Characterization of three H3N2 and one new reassortant H3N8 avian influenza virus in South China. Infect Genet Evol. 2019 Aug 28.  Abstract  
submitted by kickingbird at 15 days ago from Infect Genet Evol. 2019 Aug 28 (via https://www.sciencedirect.com/science/article/pii/S156713481)
Three H3N2 and one H3N8 avian influenza virus-positive isolates from live poultry market in Guangdong province during november 2018.?Our study found the genes of the new reassortant H3N8 were deriver from ...

Ito T, et al. Transient depression of myocardial function after influenza virus infection: A study of echocardiographic tissue imaging. PLoS One. 2019 Aug 23;14(8):e0221628.  Abstract  
submitted by kickingbird at Aug, 29, 2019 from PLoS One. 2019 Aug 23;14(8):e0221628 (via https://journals.plos.org/plosone/article?id=10.1371/journal)
BACKGROUND: Influenza virus infection (IVI) was reported to be associated with minor cardiac changes, mostly those detected on electrocardiogram with and without elevated blood markers of myocardial injury; ...

Wang H, Dou D, ?stbye H, Revol R, Daniels R. Structural restrictions for influenza neuraminidase activity promote adaptation and diversification. Nat Microbiol. 2019 Aug 26..  Abstract  
submitted by kickingbird at Aug, 29, 2019 from Nat Microbiol. 2019 Aug 26. (via https://www.nature.com/articles/s41564-019-0537-z)
Influenza neuraminidase (NA) is a sialidase that contributes to viral mobility by removing the extracellular receptors for the haemagglutinin (HA) glycoprotein. However, it remains unclear why influenza ...

Kenney AD, et al. IFITM3 protects the heart during influenza virus infection. Proc Natl Acad Sci U S A. 2019 Aug 26..  Abstract  
submitted by kickingbird at Aug, 29, 2019 from Proc Natl Acad Sci U S A. 2019 Aug 26. (via https://www.pnas.org/content/early/2019/08/23/1900784116)
Influenza virus can disseminate from the lungs to the heart in severe infections and can induce cardiac pathology, but this has been difficult to study due to a lack of small animal models. In humans, ...

Lee RTC, et al. Influenza A Hemagglutinin Passage Bias Sites and Host Specificity Mutations. Cells. 2019 Aug 22;8(9)..  Abstract  
submitted by kickingbird at Aug, 27, 2019 from Cells. 2019 Aug 22;8(9). (via https://www.mdpi.com/2073-4409/8/9/958)
Animal studies aimed at understanding influenza virus mutations that change host specificity to adapt to replication in mammalian hosts are necessarily limited in sample numbers due to high cost and safety ...

Gilbertson B, et al. Inhibition of Influenza A Virus by Human Infant Saliva. Viruses. 2019 Aug 20;11(8).  Abstract  
submitted by kickingbird at Aug, 25, 2019 from Viruses. 2019 Aug 20;11(8) (via https://www.mdpi.com/1999-4915/11/8/766)
Innate antiviral factors in saliva play a role in protection against respiratory infections. We tested the anti-influenza virus activities of saliva samples taken from human infants, 1-12 months old, with ...

Wang Y, et al. Influenza Virus Infection Induces ZBP1 Expression and Necroptosis in Mouse Lungs. Front Cell Infect Microbiol. 2019 Aug 7;9:286..  Abstract  
submitted by kickingbird at Aug, 25, 2019 from Front Cell Infect Microbiol. 2019 Aug 7;9:286. (via https://www.frontiersin.org/articles/10.3389/fcimb.2019.0028)
Programmed cell death and especially necroptosis, a programmed and regulated form of necrosis, have been recently implicated in the progression and outcomes of influenza in mouse models. Moreover, Z-DNA/RNA ...

Suttie A, et al. Inventory of molecular markers affecting biological characteristics of avian influenza A viruses. Virus Genes. 2019 Aug 19..  Abstract  
submitted by kickingbird at Aug, 21, 2019 from Virus Genes. 2019 Aug 19. (via https://link.springer.com/article/10.1007%2Fs11262-019-01700)
Avian influenza viruses (AIVs) circulate globally, spilling over into domestic poultry and causing zoonotic infections in humans. Fortunately, AIVs are not yet capable of causing sustained human-to-human ...

Pulit-Penaloza JA, et al. Mammalian pathogenicity and transmissibility of a reassortant Eurasian avian-like A(H1N1v) influenza virus associated with human infection in China (2015). Virology. 2019 Aug 10;537:31-35..  Abstract  
submitted by kickingbird at Aug, 21, 2019 from Virology. 2019 Aug 10;537:31-35. (via https://www.sciencedirect.com/science/article/abs/pii/S00426)
Swine-origin (variant) H1 influenza A viruses associated with numerous human infections in North America in recent years have been extensively studied in vitro and in mammalian models to determine their ...

Shen Q, Cho JH. The structure and conformational plasticity of the nonstructural protein 1 of the 1918 influenza A virus. Biochem Biophys Res Commun. 2019 Aug 14..  Abstract  
submitted by kickingbird at Aug, 21, 2019 from Biochem Biophys Res Commun. 2019 Aug 14. (via https://www.sciencedirect.com/science/article/pii/S0006291X1)
Nonstructural protein 1 (NS1) is a multifunctional virulence factor of influenza virus. The effector domain (ED) of influenza viruses is capable of binding to a variety of host factors, however, the molecular ...

Arikata M, et al. Efficacy of clarithromycin against H5N1 and H7N9 avian influenza a virus infection in cynomolgus monkeys. Antiviral Res. 2019 Aug 14:1.  Abstract  
submitted by kickingbird at Aug, 21, 2019 from Antiviral Res. 2019 Aug 14:1 (via https://www.sciencedirect.com/science/article/pii/S016635421)
Clarithromycin (CAM), a 14-membered ring macrolide, has anti-inflammatory and immunomodulatory actions and antiviral effects in seasonal influenza virus infection. We examined the prophylactic and therapeutic ...

Ujie M, et al. Long-term culture of human lung adenocarcinoma A549 cells enhances the replication of human influenza A viruses. J Gen Virol. 2019 Aug 19..  Abstract  
submitted by kickingbird at Aug, 21, 2019 from J Gen Virol. 2019 Aug 19. (via https://www.microbiologyresearch.org/content/journal/jgv/10.)
Long-term culture of the human lung adenocarcinoma cell line A549 promotes the differentiation of these cells toward an alveolar type II cell phenotype. Here, we evaluated the susceptibility of long-term ...

Hay JA, Laurie K, White M, Riley S. Characterising antibody kinetics from multiple influenza infection and vaccination events in ferrets. PLoS Comput Biol. 2019 Aug 19;15(8):e1007294.  Abstract  
submitted by kickingbird at Aug, 21, 2019 from PLoS Comput Biol. 2019 Aug 19;15(8):e1007294 (via https://journals.plos.org/ploscompbiol/article?id=10.1371/jo)
The strength and breadth of an individual's antibody repertoire is an important predictor of their response to influenza infection or vaccination. Although progress has been made in understanding qualitatively ...

Yu J, et al. Development and characterization of a reverse genetics system for influenza D virus. J Virol. 2019 Aug 14..  Abstract  
submitted by kickingbird at Aug, 18, 2019 from J Virol. 2019 Aug 14. (via https://jvi.asm.org/content/early/2019/08/08/JVI.01186-19)
Influenza D virus (IDV) of the Orthomyxoviridae family has a wide host range and a broad geographical distribution. Recent IDV outbreaks in swine, along with serological and genetic evidence of IDV infection ...

Calderon BM, et al. Dysregulation of M segment gene expression contributes to influenza A virus host restriction. PLoS Pathog. 2019 Aug 15;15(8):e1007892.  Abstract  
submitted by kickingbird at Aug, 18, 2019 from PLoS Pathog. 2019 Aug 15;15(8):e1007892 (via https://journals.plos.org/plospathogens/article?id=10.1371/j)
The M segment of the 2009 pandemic influenza A virus (IAV) has been implicated in its emergence into human populations. To elucidate the genetic contributions of the M segment to host adaptation, and the ...

Liu YM, et al. Exosome-delivered and Y RNA-derived small RNA suppresses influenza virus replication. J Biomed Sci. 2019 Aug 15;26(1):58.  Abstract  
submitted by kickingbird at Aug, 18, 2019 from J Biomed Sci. 2019 Aug 15;26(1):58 (via https://jbiomedsci.biomedcentral.com/articles/10.1186/s12929)
BACKGROUND: Multiple interplays between viral and host factors are involved in influenza virus replication and pathogenesis. Several small RNAs have recently emerged as important regulators of host response ...

Zheng S, et al. Factors associated with fatality due to avian influenza A(H7N9) infection in China. Clin Infect Dis. 2019 Aug 16.  Abstract  
submitted by kickingbird at Aug, 18, 2019 from Clin Infect Dis. 2019 Aug 16 (via https://academic.oup.com/cid/advance-article-abstract/doi/10)
BACKGROUND: The high case fatality rate of influenza A H7N9 infected patients has been a major clinical concern.METHODS: To identify the common causes of death due to H7N9 as well as identify risk factors ...

Wan H, et al. The neuraminidase of A(H3N2) influenza viruses circulating since 2016 is antigenically distinct from the A/Hong Kong/4801/2014 vaccine strain. Nat Microbiol. 2019 Aug 12..  Abstract  
submitted by kickingbird at Aug, 15, 2019 from Nat Microbiol. 2019 Aug 12. (via https://www.nature.com/articles/s41564-019-0522-6)
A(H3N2) virus predominated recent influenza seasons, which has resulted in the rigorous investigation of haemagglutinin, but whether neuraminidase (NA) has undergone antigenic change and contributed to ...

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