Iwatsuki-Horimoto K, Uraki R, Ito M, Wang T, Guan. Transmission of bovine H5N1 virus in a hamster model. J Virol. 2025 Mar 25:e0014725. Abstract submitted by kickingbird at 6 days ago from J Virol. 2025 Mar 25:e0014725 (via https://journals.asm.org/doi/10.1128/jvi.00147-25) Transmission among mammals of bovine highly pathogenic avian influenza (HPAI) H5N1 viruses, which have caused outbreaks in US dairy cattle, has been demonstrated in ferrets by our group (4, 5) and the ... Li X, Li A, Qu F, Li Y, Chen F, Lv X, An Q, Fei M,. Evaluation of Global Distribution, Genetic Evolution, and Mammalian Infectivity and Pathogenicity of H13 and H16 Avian Influenza Viruses. Emerg Microbes Infect. 2025 Mar 25:2482695. Abstract submitted by kickingbird at 6 days ago from Emerg Microbes Infect. 2025 Mar 25:2482695 (via https://pubmed.ncbi.nlm.nih.gov/40130325/) H13 and H16 subtype avian influenza viruses (AIVs) typically infect Charadriiformes, are widely distributed throughout coastal regions worldwide, and pose a risk of spillover to mammals. Systematic research ... Liu CC, Ru YX, Li HR, Liu DJ, Liu JY, Zhao SL, Wu. Soluble influenza H3 trimer proteins enhance the breadth and potency of antibody response. Int J Biol Macromol. 2025 Mar 19;307(Pt 4):142240. Abstract submitted by kickingbird at 7 days ago from Int J Biol Macromol. 2025 Mar 19;307(Pt 4):142240 (via https://www.sciencedirect.com/science/article/abs/pii/S01418) Seasonal influenza poses a continuing threat to public health. The effectiveness of the influenza vaccine varies across seasons, with protection against H3N2 being notably less reliable. A primary contributor ... Sen TK, Jing L, Anand A, Zhang Ryan LZ, Ting HT, H. Unique Immune and Other Responses of Human Nasal Epithelial Cells Infected with H5N1 Avian Influenza Virus Compared to Seasonal Human Influenza A and B Viruses. Emerg Microbes Infect. 2025 Mar 24:2484330. Abstract submitted by kickingbird at 7 days ago from Emerg Microbes Infect. 2025 Mar 24:2484330 (via https://pubmed.ncbi.nlm.nih.gov/40126073/) Highly pathogenic avian influenza (HPAI) virus (e.g. H5N1) infects the lower airway to cause severe infections, and constitute a prime candidate for the emergence of disease X. The nasal epithelium is ... Nicole Lenz-Ajuh, etc.,al. [preprint]Impact of pH and temperature in dairy processing on the infectivity of H5N1 avian influenza viruses. https://doi.org/10.1101/2025.03.21.644501. Abstract submitted by kickingbird at 9 days ago from https://doi.org/10.1101/2025.03.21.644501 (via https://www.biorxiv.org/content/10.1101/2025.03.21.644501v1) Highly pathogenic avian influenza viruses (HPAIV) of subtype H5N1 (clade 2.3.4.4b) have crossed the species barrier and caused a mastitis-like infection in dairy cows. The high levels of infectious virus ... Amber L Pillar, etc.,al. [preprint]Crucial role for iron metabolism in mediating influenza A virus infection and associated disease. https://doi.org/10.1101/2025.03.20.644262. Abstract submitted by kickingbird at 9 days ago from https://doi.org/10.1101/2025.03.20.644262 (via https://www.biorxiv.org/content/10.1101/2025.03.20.644262v1) Rationale and Objectives: Iron availability and metabolism are important in the pathogenesis of bacterial infections. More recently, links have been reported between iron and the severity of viral infections. ... Ford, Colby T. et al. Large-scale computational modelling of H5 influenza variants against HA1-neutralising antibodies. eBioMedicine, Volume 114, 105632. Abstract submitted by kickingbird at 11 days ago from eBioMedicine, Volume 114, 105632 (via https://www.thelancet.com/journals/ebiom/article/PIIS2352-39) BackgroundThe United States Department of Agriculture has recently released reports that show samples collected from 2022 to 2025 of highly pathogenic avian influenza (H5N1) have been detected in mammals ... Mingsheng Zhao, etc.,al. Genetic Evolution and Molecular Characteristics of Avian Influenza Viruses in Jining from 2018 to 2023. Front. Microbiol. Volume 16, 2025. Abstract submitted by kickingbird at 11 days ago from Front. Microbiol. Volume 16, 2025 (via https://www.frontiersin.org/journals/microbiology/articles/1) Objective This study aimed to analyze the genetic evolution and molecular characteristics of H5, H7, and H9 subtypes of avian influenza viruses in the external environment of poultry in Jining from 2018 ... Sebastian Bittrich, etc.,al. Visualizing and analyzing 3D biomolecular structures using Mol* at RCSB.org: Influenza A H5N1 virus proteome case study. TOOLS FOR PROTEIN SCIENCE. Abstract submitted by kickingbird at 11 days ago from TOOLS FOR PROTEIN SCIENCE (via https://onlinelibrary.wiley.com/doi/10.1002/pro.70093) The easiest and often most useful way to work with experimentally determined or computationally predicted structures of biomolecules is by viewing their three-dimensional (3D) shapes using a molecular ... David J Bacsik, etc.,al. [preprint]Validation of H5 influenza virus subtyping RT-qPCR assay and low prevalence of H5 detection in 2024-2025 influenza virus season. https://doi.org/10.1101/2025.03.17.25324122. Abstract submitted by kickingbird at 11 days ago from https://doi.org/10.1101/2025.03.17.25324122 (via https://www.medrxiv.org/content/10.1101/2025.03.17.25324122v) A sustained outbreak of H5N1 influenza virus among wild fowl and domestic livestock has caused more than 70 zoonotic infections in humans in the United States, including one death. The Centers for Disease ... Daniel Janies, etc.,al. [preprint]Analyses of phylogenetics, natural selection, and protein structure of clade 2.3.4.4b H5N1 Influenza A reveal that recent viral lineages have evolved promiscuity in host range and improved r. https://doi.org/10.1101/2025.03.15.641219. Abstract submitted by kickingbird at 11 days ago from https://doi.org/10.1101/2025.03.15.641219 (via https://www.biorxiv.org/content/10.1101/2025.03.15.641219v1) H5N1 influenza has been circulating in birds from Eurasia and Africa for more than 146 years, but human infection has been sporadic. H5N1 (clade 2.3.4.4b) has recently infected hundreds of species of wild ... David Scheibner, etc.,al. [preprint]Different genetic determinants for high virulence, transmission and replication of high pathogenicity H7N7 avian influenza virus in turkeys and chickens. https://doi.org/10.1101/2025.03.18.643940. Abstract submitted by kickingbird at 11 days ago from https://doi.org/10.1101/2025.03.18.643940 (via https://www.biorxiv.org/content/10.1101/2025.03.18.643940v1) High pathogenicity (HP) avian influenza viruses (AIV) generally evolve from low pathogenicity (LP) precursors after transmission from wild birds to chickens (Gallus gallus domesticus) and turkeys (Meleagris ... Jessica A Belser, etc.,al. Ocular infectivity and replication of a clade 2.3.4.4b A(H5N1) influenza virus associated with human conjunctivitis in a dairy farm worker in the USA: an in-vitro and ferret study. The Lancet Microbe. Abstract submitted by kickingbird at 11 days ago from The Lancet Microbe (via https://www.sciencedirect.com/science/article/pii/S266652472) SummaryBackgroundThe human eye represents a potential site of influenza A virus (IAV) replication, and an entry point for the virus to reach the respiratory tract. The frequent detection of conjunctivitis ... Zhao C, Huang J, Zhang C, Wang Y, Zhang X, Liu S,. Characteristics of the First Domestic Duck-Origin H12N8 Avian Influenza Virus in China. International Journal of Molecular Sciences. 2025;. Abstract submitted by kickingbird at 11 days ago from International Journal of Molecular Sciences. 2025; (via https://www.mdpi.com/1422-0067/26/6/2740) The H12 subtypes of avian influenza viruses (AIVs) are globally prevalent in wild birds, occasionally spilling over into poultry. In this study, we isolated an H12N8 virus from ducks in a live poultry ... Jones JC, Andreev K, Fabrizio TP, Bowman AS, Govor. Baloxavir improves disease outcomes in mice after intranasal or ocular infection with Influenza A virus H5N1-contaminated cow´s milk. Nat Microbiol. 2025 Mar 17. Abstract submitted by kickingbird at 12 days ago from Nat Microbiol. 2025 Mar 17 (via https://www.nature.com/articles/s41564-025-01961-5) Testing approved antivirals against A(H5N1) influenza viruses circulating in peridomestic species, including dairy cows, is critical to public health and pre-pandemic planning. It cannot be tested in humans ... Mohammed Nooruzzaman, etc.,al. [preprint]Stability of influenza A H5N1 virus in raw milk cheese. https://doi.org/10.1101/2025.03.13.643009. Abstract submitted by kickingbird at Mar, 14, 2025 from https://doi.org/10.1101/2025.03.13.643009 (via https://www.biorxiv.org/content/10.1101/2025.03.13.643009v1) We evaluated the stability of highly pathogenic avian influenza (HPAI) H5N1 virus in raw milk cheeses using a mini cheese model prepared with HPAI-spiked raw milk under varying pH levels (pH 6.6, 5.8 and ... Octaviani, C.P., Huang, P., Bi-Hung, P. et al. Superior replication, pathogenicity, and immune evasion of a Texas dairy cattle H5N1 virus compared to a historical avian isolate. Sci Rep 15, 8797 (2025). Abstract submitted by kickingbird at Mar, 14, 2025 from Sci Rep 15, 8797 (2025) (via https://link.springer.com/article/10.1038/s41598-025-93493-5) The current outbreak of highly pathogenic avian influenza (HPAI) viruses of the H5N1 subtype clade 2.3.4.4b in dairy cattle in the United States has affected nearly 900 dairy farms and resulted in at least ... Smith VA, Schall AR, Tomsho JW. Nonstructural Protein 1 of Influenza A (NS1A) Demonstrates Strain-Specific dsRNA Binding Capabilities. ACS Infect Dis. 2025 Mar 13. Abstract submitted by kickingbird at Mar, 14, 2025 from ACS Infect Dis. 2025 Mar 13 (via https://pubs.acs.org/doi/10.1021/acsinfecdis.4c00882) Nonstructural protein 1 of influenza A (NS1A) is a key virulence factor produced inside host cells infected with Influenza A Virus (IAV) and consists of an N-terminal dsRNA binding domain (RBD) and a C-terminal ... Garretson, T.A., Liu, J., Li, S.H. et al. Immune history shapes human antibody responses to H5N1 influenza viruses. Nat Med (2025). Abstract submitted by kickingbird at Mar, 13, 2025 from Nat Med (2025) (via https://www.nature.com/articles/s41591-025-03599-6) Avian H5N1 influenza viruses are circulating widely in cattle and other mammals and pose a risk for a human pandemic. Previous studies suggest that older humans are more resistant to H5N1 infections due ... Edoardo Giussani, Alessandro Sartori, Angela Salom. FluMut: a tool for mutation surveillance in highly pathogenic H5N1 genomes. Virus Evolution, 2025; veaf011. Abstract submitted by kickingbird at Mar, 13, 2025 from Virus Evolution, 2025; veaf011 (via https://academic.oup.com/ve/advance-article/doi/10.1093/ve/v) Over the past century, Influenza A virus (IAV) has caused four of the five reported pandemics, all of which originated from viruses possessing genome segments of avian origin. The recent spread of highly ... 5856 items, 20/Page, Page[2/293][|<<] [|<] [1] [2] [3] [4] [5] [6] [7] [8] [9] [10] [>|] [>>|] |
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