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2020-2-28 23:38:51
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Lee DH, Criado MF, Swayne DE. Pathobiological Origins and Evolutionary History of Highly Pathogenic Avian Influenza Viruses. Cold Spring Harb Perspect Med. 2020 Jan 21..  Abstract  
submitted by kickingbird at Jan, 25, 2020 from Cold Spring Harb Perspect Med. 2020 Jan 21. (via http://perspectivesinmedicine.cshlp.org/content/early/2020/0)
High-pathogenicity avian influenza (HPAI) viruses have arisen from low-pathogenicity avian influenza (LPAI) viruses via changes in the hemagglutinin proteolytic cleavage site, which include mutation of ...

Wang D, Zhu W, Yang L, Shu Y. The Epidemiology, Virology, and Pathogenicity of Human Infections with Avian Influenza Viruses. Cold Spring Harb Perspect Med. 2020 Jan 21.  Abstract  
submitted by kickingbird at Jan, 25, 2020 from Cold Spring Harb Perspect Med. 2020 Jan 21 (via http://perspectivesinmedicine.cshlp.org/content/early/2020/0)
Influenza is a global challenge, and future pandemics of influenza are inevitable. One of the lessons learned from past pandemics is that all pandemic influenza viruses characterized to date possess viral ...

Kombiah S, et al. Experimental pathology of two highly pathogenic H5N1 viruses isolated from crows in BALB/c mice. Microb Pathog. 2020 Jan 20:103984..  Abstract  
submitted by kickingbird at Jan, 25, 2020 from Microb Pathog. 2020 Jan 20:103984. (via https://www.sciencedirect.com/science/article/abs/pii/S08824)
In our study we assessed the pathogenicity of two H5N1 viruses isolated from crows in mice. Eighteen 6-8 weeks BALB/c mice each were intranasally inoculated with 106 EID50/ml of H5N1 viruses A/crow/India/03CA04/2015 ...

Root JJ, Ellis JW, Shriner SA. Effects of freshwater crayfish on influenza A virus persistence in water. Zoonoses Public Health. 2020 Jan 20..  Abstract  
submitted by kickingbird at Jan, 21, 2020 from Zoonoses Public Health. 2020 Jan 20. (via https://onlinelibrary.wiley.com/doi/abs/10.1111/zph.12688)
Several investigations have recently assessed the ability of some aquatic invertebrates to act as tools for avian influenza A virus (IAV) surveillance as well as their potential role(s) in IAV ecology. ...

Zou S, et al. Molecular characterization of H3 subtype avian influenza viruses based on poultry-related environmental surveillance in China between 2014 and 2017. Virology. 2020 Jan 11;542:8-19.  Abstract  
submitted by kickingbird at Jan, 21, 2020 from Virology. 2020 Jan 11;542:8-19 (via https://www.sciencedirect.com/science/article/abs/pii/S00426)
The H3 subtype avian influenza virus (AIV) poses a threat to both animal and human health. In this study, phylogenetic analysis showed that the H3 AIVs had various genomic constellations and extensive ...

Ou J, Chen R, Yan Z, Ou S, Dong N, Lu G, Li S. Codon usage bias of H3N8 equine influenza virus- an evolutionary perspective. J Infect. 2020 Jan 17..  Abstract  
submitted by kickingbird at Jan, 21, 2020 from J Infect. 2020 Jan 17. (via https://www.journalofinfection.com/article/S0163-4453(20)300)
Recently, several reports in the Journal of Infection have demonstrated the codon usage bias of influenza virus.1–3 Equine influenza (EI) is a severe and highly contagious disease in horses. Equine influenza ...

Moncla LH, et al. Quantifying within-host diversity of H5N1 influenza viruses in humans and poultry in Cambodia. PLoS Pathog. 2020 Jan 17;16(1):e1008191.  Abstract  
submitted by kickingbird at Jan, 20, 2020 from PLoS Pathog. 2020 Jan 17;16(1):e1008191 (via https://journals.plos.org/plospathogens/article?id=10.1371/j)
Avian influenza viruses (AIVs) periodically cross species barriers and infect humans. The likelihood that an AIV will evolve mammalian transmissibility depends on acquiring and selecting mutations during ...

Le TB, et al. Development of a Multiplex RT-qPCR for the Detection of Different Clades of Avian Influenza in Poultry. Viruses. 2020 Jan 15;12(1)..  Abstract  
submitted by kickingbird at Jan, 20, 2020 from Viruses. 2020 Jan 15;12(1). (via https://www.mdpi.com/1999-4915/12/1/100)
Since the initial detection of H5N1, a highly pathogenic avian influenza (HPAI) virus, in 1996 in China, numerous HPAI H5 lineages have been classified, and they continue to pose a threat to animal and ...

Ahmed BM, et al. Evaluating two approaches for using positive control in standardizing the avian influenza H5 reverse transcription recombinase polymerase amplification assay. Mol Cell Probes. 2020 Jan 14:101511..  Abstract  
submitted by kickingbird at Jan, 20, 2020 from Mol Cell Probes. 2020 Jan 14:101511. (via https://www.sciencedirect.com/science/article/abs/pii/S08908)
Highly pathogenic avian influenza H5N1 virus causes heavy losses in poultry farms worldwide. Molecular diagnostic techniques like RT-PCR and real-time RT-PCR are considered the gold standard for identification ...

Chen J, et al. Specificity, Kinetics and Longevity of Antibody Responses to Avian Influenza A(H7N9) Virus Infection in Humans. J Infect. 2020 Jan 16..  Abstract  
submitted by kickingbird at Jan, 20, 2020 from J Infect. 2020 Jan 16. (via https://www.journalofinfection.com/article/S0163-4453(20)300)
OBJECTIVES: The long-term dynamics of antibody responses in patients with influenza A(H7N9) virus infection are not well understood.METHODS: We conducted a longitudinal serological follow-up study in patients ...

Kato-Miyashita S, et al. Antigenic variants of influenza B viruses isolated in Japan during the 2017-2018 and 2018-2019 influenza seasons. Influenza Other Respir Viruses. 2020 Jan 19..  Abstract  
submitted by kickingbird at Jan, 20, 2020 from Influenza Other Respir Viruses. 2020 Jan 19. (via https://onlinelibrary.wiley.com/doi/full/10.1111/irv.12713)
BACKGROUND: Here, we genetically and antigenically analyzed influenza B viruses (IBVs) isolated in Japan during the 2017-2018 and 2018-2019 influenza seasons.METHODS: A total of 68 IBVs (61 B/Yamagata/16/88-like ...

Chan M, et al. H7N9 Influenza Virus Containing a Polybasic HA Cleavage Site Requires Minimal Host Adaptation to Obtain a Highly Pathogenic Disease Phenotype in Mice. Viruses. 2020 Jan 5;12(1)..  Abstract  
submitted by kickingbird at Jan, 19, 2020 from Viruses. 2020 Jan 5;12(1). (via https://www.mdpi.com/1999-4915/12/1/65)
Low pathogenic avian influenza (LPAI) H7N9 viruses have recently evolved to gain a polybasic cleavage site in the hemagglutinin (HA) protein, resulting in variants with increased lethality in poultry that ...

Qu B, Li X, Cardona CJ, Xing Z. Reassortment and adaptive mutations of an emerging avian influenza virus H7N4 subtype in China. PLoS One. 2020 Jan 17;15(1):e0227597..  Abstract  
submitted by kickingbird at Jan, 19, 2020 from PLoS One. 2020 Jan 17;15(1):e0227597. (via https://journals.plos.org/plosone/article?id=10.1371/journal)
Human infections with avian influenza viruses including H5, H7 and H9 hemagglutinin subtypes occur at a low rate. Among human infections with H7 viruses, regional outbreaks with H7N2, H7N3, H7N7 and H7N9 ...

Aegerter H, et al. Influenza-induced monocyte-derived alveolar macrophages confer prolonged antibacterial protection. Nat Immunol. 2020 Jan 13.  Abstract  
submitted by kickingbird at Jan, 17, 2020 from Nat Immunol. 2020 Jan 13 (via https://www.nature.com/articles/s41590-019-0568-x)
Despite the prevalence and clinical importance of influenza, its long-term effect on lung immunity is unclear. Here we describe that following viral clearance and clinical recovery, at 1?month after infection ...

Kupke SY, et al. Single-Cell Analysis Uncovers a Vast Diversity in Intracellular Viral Defective Interfering RNA Content Affecting the Large Cell-to-Cell Heterogeneity in Influenza A Virus Replication. Viruses. 2020 Jan 7;12(1).  Abstract  
submitted by kickingbird at Jan, 17, 2020 from Viruses. 2020 Jan 7;12(1) (via https://www.mdpi.com/1999-4915/12/1/71)
Virus replication displays a large cell-to-cell heterogeneity; yet, not all sources of this variability are known. Here, we study the effect of defective interfering (DI) particle (DIP) co-infection on ...

Daidoji T, et al. Infection of Human Tracheal Epithelial Cells by H5 Avian Influenza Virus Is Regulated by the Acid Stability of Hemagglutinin and the pH of Target Cell Endosomes. Viruses. 2020 Jan 9;12(1).  Abstract  
submitted by kickingbird at Jan, 17, 2020 from Viruses. 2020 Jan 9;12(1) (via https://www.mdpi.com/1999-4915/12/1/82)
Despite the possible relationships between tracheal infection and concomitant infection of the terminal part of the lower respiratory tract (bronchioles/alveoli), the behavior of avian influenza viruses ...

Novoseltseva AA, et al. Structural and Functional Aspects of G-Quadruplex Aptamers Which Bind a Broad Range of Influenza A Viruses. Biomolecules. 2020 Jan 10;10(1).  Abstract  
submitted by kickingbird at Jan, 17, 2020 from Biomolecules. 2020 Jan 10;10(1) (via https://www.mdpi.com/2218-273X/10/1/119)
An aptamer is a synthetic oligonucleotide with a unique spatial structure that provides specific binding to a target. To date, several aptamers to hemagglutinin of the influenza A virus have been described, ...

Wang C, et al. Cell-to-Cell Variation in Defective Virus Expression and Effects on Host Responses during Influenza Virus Infection. mBio. 2020 Jan 14;11(1). pii: e02880-19..  Abstract  
submitted by kickingbird at Jan, 17, 2020 from mBio. 2020 Jan 14;11(1). pii: e02880-19. (via https://mbio.asm.org/content/11/1/e02880-19)
Virus and host factors contribute to cell-to-cell variation in viral infections and determine the outcome of the overall infection. However, the extent of the variability at the single-cell level and how ...

Tare DS, Kode SS, Hurt AC, Pawar SD. Assessing the susceptibility of highly pathogenic avian influenza H5N1 viruses to oseltamivir using embryonated chicken eggs. Indian J Med Res. 2019 Nov;150(5):486-491..  Abstract  
submitted by kickingbird at Jan, 17, 2020 from Indian J Med Res. 2019 Nov;150(5):486-491. (via http://www.ijmr.org.in/article.asp?issn=0971-5916;year=2019;)
Background & objectives: The susceptibility of influenza viruses to neuraminidase inhibitors (NAIs) is studied using enzyme-based assays, sequence analysis and in vitro and in vivo studies. Oseltamivir ...

Covés-Datson EM, et al. A molecularly engineered antiviral banana lectin inhibits fusion and is efficacious against influenza virus infection in vivo. Proc Natl Acad Sci U S A. 2020 Jan 13.  Abstract  
submitted by kickingbird at Jan, 16, 2020 from Proc Natl Acad Sci U S A. 2020 Jan 13 (via https://www.pnas.org/content/early/2020/01/09/1915152117)
There is a strong need for a new broad-spectrum antiinfluenza therapeutic, as vaccination and existing treatments are only moderately effective. We previously engineered a lectin, H84T banana lectin (H84T), ...

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