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2019-7-24 5:11:34

Lee DH, et al. Genome Sequences of an H9N2 Avian Influenza Virus Strain Found in Pakistan in 2017. Microbiol Resour Announc. 2019 Jul 11;8(28)..  Abstract  
submitted by kickingbird at 9 days ago from Microbiol Resour Announc. 2019 Jul 11;8(28). (via https://mra.asm.org/content/8/28/e00433-19)
In 2017, we isolated an H9N2 avian influenza virus in Pakistan. Genetic analysis showed that the A/chicken/Kasoor/SI36/2017(H9N2) isolate belongs to the G1 lineage. In addition, this isolate possesses ...

Mishin VP, Patel MC, Chesnokov A, De La Cruz J, Ng. Susceptibility of Influenza A, B, C, and D Viruses to Baloxavir. Emerg Infect Dis. 2019 Oct.  Abstract  
submitted by kickingbird at 12 days ago from Emerg Infect Dis. 2019 Oct (via https://wwwnc.cdc.gov/eid/article/25/10/19-0607_article)
Baloxavir showed broad-spectrum in vitro replication inhibition of 4 types of influenza viruses (90% effective concentration range 1.2-98.3 nmol/L); susceptibility pattern was influenza A ? B ? C ? D. ...

Wang G, et al. Characterization of swine-origin H1N1 canine influenza viruses. Emerg Microbes Infect. 2019;8(1):1017-1026.  Abstract  
submitted by kickingbird at 12 days ago from Emerg Microbes Infect. 2019;8(1):1017-1026 (via https://www.tandfonline.com/doi/full/10.1080/22221751.2019.1)
Host switch events of influenza A viruses (IAVs) continuously pose a zoonotic threat to humans. In 2013, swine-origin H1N1 IAVs emerged in dogs soon after they were detected in swine in the Guangxi province ...

Kode SS, et al. A novel I117T substitution in neuraminidase of highly pathogenic avian influenza H5N1 virus conferring reduced susceptibility to oseltamivir and zanamivir. Vet Microbiol. 2019 Jun 5;235:21-24..  Abstract  
submitted by kickingbird at 12 days ago from Vet Microbiol. 2019 Jun 5;235:21-24. (via https://www.sciencedirect.com/science/article/pii/S037811351)
Occurrence of avian influenza (AI) with Neuraminidase (NA) mutations which confer reduced neuraminidase inhibitor (NAI) susceptibility has remained a cause of concern. The susceptibility to NAIs of 67 ...

Peacock TP, Sheppard CM, Staller E, Barclay WS. Host Determinants of Influenza RNA Synthesis. Annu Rev Virol. 2019 Jul 5.  Abstract  
submitted by kickingbird at 12 days ago from Annu Rev Virol. 2019 Jul 5 (via https://www.annualreviews.org/doi/10.1146/annurev-virology-0)
Influenza viruses are a leading cause of seasonal and pandemic respiratory illness. Influenza is a negative-sense single-stranded RNA virus that encodes its own RNA-dependent RNA polymerase (RdRp) for ...

Huo C, et al. Genomic and Bioinformatic Characterization of Mouse Mast Cells (P815) Upon Different Influenza A Virus (H1N1, H5N1, and H7N2) Infections. Front Genet. 2019 Jun 21;10:595.  Abstract  
submitted by kickingbird at 12 days ago from Front Genet. 2019 Jun 21;10:595 (via https://www.frontiersin.org/articles/10.3389/fgene.2019.0059)
Influenza A virus (IAV) is a segmented negative-stranded RNA virus that brings a potentially serious threat to public health and animal husbandry. Mast cells play an important role in both the inherent ...

Mei K, et al. Different Pathogenicity and Transmissibility of Goose-Origin H5N6 Avian Influenza Viruses in Chickens. Viruses. 2019 Jul 4;11(7)..  Abstract  
submitted by kickingbird at 14 days ago from Viruses. 2019 Jul 4;11(7). (via https://www.mdpi.com/1999-4915/11/7/612)
Highly pathogenic avian influenza H5N6 viruses have been circulating in poultry in Asia since 2013 and producing serious diseases in chickens. Here, we analyzed the genetic properties of 10 H5N6 subtypes ...

To J, Torres J. Viroporins in the Influenza Virus. Cells. 2019 Jun 29;8(7)..  Abstract  
submitted by kickingbird at Jul, 7, 2019 from Cells. 2019 Jun 29;8(7). (via https://www.mdpi.com/2073-4409/8/7/654)
Influenza is a highly contagious virus that causes seasonal epidemics and unpredictable pandemics. Four influenza virus types have been identified to date: A, B, C, and D, where only A-C are known to infect ...

Zhang K, et al. Structural basis for influenza virus NS1 protein block of mRNA nuclear export. Nat Microbiol. 2019 Jul 1..  Abstract  
submitted by kickingbird at Jul, 7, 2019 from Nat Microbiol. 2019 Jul 1. (via https://www.nature.com/articles/s41564-019-0482-x)
Influenza viruses antagonize key immune defence mechanisms via the virulence factor non-structural protein 1 (NS1). A key mechanism of virulence by NS1 is blocking nuclear export of host messenger RNAs, ...

Watkins LC, Liang R, Swanson JMJ, DeGrado WF, Voth. Proton Induced Conformational and Hydration Dynamics in the Influenza A M2 Channel. J Am Chem Soc. 2019 Jul 2..  Abstract  
submitted by kickingbird at Jul, 7, 2019 from J Am Chem Soc. 2019 Jul 2. (via https://pubs.acs.org/doi/10.1021/jacs.9b05136)
The influenza A M2 protein is an acid-activated proton channel responsible for the acidification of the inside of the virus, a critical step in the viral life cycle. This channel has four central histidine ...

Zhou L, Li Q, Uyeki TM.. Estimated Incubation Period and Serial Interval for Human-to-Human Influenza A(H7N9) Virus Transmission. Emerg Infect Dis. 2019 Oct 17;25(10)..  Abstract  
submitted by kickingbird at Jul, 7, 2019 from Emerg Infect Dis. 2019 Oct 17;25(10). (via https://wwwnc.cdc.gov/eid/article/25/10/19-0117_article)
We estimated the incubation period and serial interval for human-to-human-transmitted avian influenza A(H7N9) virus infection using case-patient clusters from epidemics in China during 2013-2017. The median ...

Arai Y, et al. PB2 mutations arising during H9N2 influenza evolution in the Middle East confer enhanced replication and growth in mammals. PLoS Pathog. 2019 Jul 2;15(7):e1007919..  Abstract  
submitted by kickingbird at Jul, 7, 2019 from PLoS Pathog. 2019 Jul 2;15(7):e1007919. (via https://journals.plos.org/plospathogens/article?id=10.1371/j)
Avian influenza virus H9N2 has been endemic in birds in the Middle East, in particular in Egypt with multiple cases of human infections since 1998. Despite concerns about the pandemic threat posed by H9N2, ...

Tang J, et al. Highly pathogenic avian influenza H7N9 viruses with reduced susceptibility to neuraminidase inhibitors showed comparable replication capacity to their sensitive counterparts. Virol J. 2019 Jul 2;16(1):87.  Abstract  
submitted by kickingbird at Jul, 7, 2019 from Virol J. 2019 Jul 2;16(1):87 (via https://virologyj.biomedcentral.com/articles/10.1186/s12985-)
BACKGROUND: Human infection with avian influenza H7N9 virus was first reported in 2013. Since the fifth epidemic, a highly pathogenic avian influenza (HPAI) H7N9 virus has emerged and caused 33 human infections. ...

Zhu W, et al. Mammalian-adaptive mutation NP-Q357K in Eurasian H1N1 Swine Influenza viruses determines the virulence phenotype in mice. Emerg Microbes Infect. 2019;8(1):989-999..  Abstract  
submitted by kickingbird at Jul, 7, 2019 from Emerg Microbes Infect. 2019;8(1):989-999. (via https://www.tandfonline.com/doi/full/10.1080/22221751.2019.1)
It has recently been proposed that the Eurasian avian-like H1N1 (EA H1N1) swine influenza virus (SIV) is one of the most likely zoonotic viruses to cause the next influenza pandemic. Two main genotypes ...

Bradley KC, et al. Microbiota-Driven Tonic Interferon Signals in Lung Stromal Cells Protect from Influenza Virus Infection. Cell Rep. 2019 Jul 2;28(1):245-256.e4.  Abstract  
submitted by kickingbird at Jul, 7, 2019 from Cell Rep. 2019 Jul 2;28(1):245-256.e4 (via https://www.cell.com/cell-reports/fulltext/S2211-1247(19)307)
Type I interferon (IFNα/β) pathways are fine-tuned to elicit antiviral protection while minimizing immunopathology; however, the initiating stimuli, target tissues, and underlying mechanisms are unclear. ...

Li X, Gao Y, Ye Z. A Single Amino Acid Substitution at Residue 218 of Hemagglutinin Improves the Growth of Influenza A(H7N9) Candidate Vaccine Viruses. J Virol. 2019 Jul 3. pii: JVI.00570-19.  Abstract  
submitted by kickingbird at Jul, 7, 2019 from J Virol. 2019 Jul 3. pii: JVI.00570-19 (via https://jvi.asm.org/content/early/2019/06/27/JVI.00570-19)
The potential avian influenza pandemic remains a threat to public health, as the avian-originated influenza A(H7N9) virus has caused more than 1560 laboratory-confirmed human infections since 2013, with ...

Cohen L, et al. A Modular Cytokine Analysis Method Reveals Novel Associations With Clinical Phenotypes and Identifies Sets of Co-signaling Cytokines Across Influenza Natural Infection Cohorts and Healthy Controls. Front Immunol. 2019 Jun 18.  Abstract  
submitted by kickingbird at Jul, 7, 2019 from Front Immunol. 2019 Jun 18 (via https://www.frontiersin.org/articles/10.3389/fimmu.2019.0133)
Cytokines and chemokines are key signaling molecules of the immune system. Recent technological advances enable measurement of multiplexed cytokine profiles in biological samples. These profiles can then ...

Boumart Z, et al. Pathogenicity and Full Genome Sequencing of the Avian Influenza H9N2 Moroccan Isolate 2016. Avian Dis. 2018 Nov 16;63(1):24-30.  Abstract  
submitted by kickingbird at Jul, 2, 2019 from Avian Dis. 2018 Nov 16;63(1):24-30 (via https://bioone.org/journals/Avian-Diseases/volume-63/issue-1)
In Morocco in early 2016, a low pathogenic avian influenza virus serotype H9N2 caused large economic losses to the poultry industry, with specific clinical symptoms and high mortality rates on infected ...

Guo F, et al. Adaptive Evolution of Human-Isolated H5Nx Avian Influenza A Viruses. Front Microbiol. 2019 Jun 12;10:1328.  Abstract  
submitted by kickingbird at Jul, 2, 2019 from Front Microbiol. 2019 Jun 12;10:1328 (via https://www.frontiersin.org/articles/10.3389/fmicb.2019.0132)
Avian influenza A viruses (AIVs) H5N1, first identified in 1996, are highly pathogenic in domestic poultry and continue to occasionally infect humans. In this study, we sought to identify genetic changes ...

Spackman E, et al. Clade H5 North American Highly Pathogenic Avian Influenza Viruses Infect, but Do Not Cause Clinical Signs in, American Black Ducks (Anas rubripes).. Avian Dis. 2019 Jan 18;63(2):366-370.  Abstract  
submitted by kickingbird at Jul, 2, 2019 from Avian Dis. 2019 Jan 18;63(2):366-370 (via https://www.ncbi.nlm.nih.gov/pubmed/31251539)
Highly pathogenic avian influenza virus (HPAIV) from the goose/Guangdong/1996 clade H5 lineage spread from Asia into North America in 2014, most likely by wild bird migrations. Although several ...

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