ODAGIRI T, Matsuzaki Y, Okamoto M, Suzuki A, et al. Isolation and characterization of influenza C viruses in the Philippines and Japan. J Clin Microbiol. 2014 Dec 31. pii: JCM.02628.. Abstract
submitted by kickingbird at Jan, 4, 2015 from J Clin Microbiol. 2014 Dec 31. pii: JCM.02628. (via http://www.ncbi.nlm.nih.gov/m/pubmed/25552361/)
From November 2009 to December 2013, 15 influenza C viruses were isolated, using MDCK cells, from specimens obtained from children with severe pneumonia and influenza-like illness (ILI), in the Philippines. ... WJ Song, etc.,al. The K526R substitution in viral protein PB2 enhances the effects of E627K on influenza virus replication. Nature Communications 5, Article number: 5509, doi. Abstract
submitted by kickingbird at Nov, 22, 2014 from Nature Communications 5, Article number: 5509, doi (via http://www.nature.com/ncomms/2014/141120/ncomms6509/abs/ncom)
Host-adaptive strategies, such as the E627K substitution in the ?PB2 protein, are critical for replication of avian influenza A viruses in mammalian hosts. Here we show that mutation ?PB2-K526R is present ... MR.Gomma, AS Kayed, etc.,al. Avian Influenza A(H5N1) and A(H9N2) Seroprevalence and Risk Factors for Infection Among Egyptians: A Prospective, Controlled Seroepidemiological Study. J Infect Dis. (2014). Abstract
submitted by kickingbird at Nov, 2, 2014 from J Infect Dis. (2014) (via http://jid.oxfordjournals.org/content/early/2014/10/25/infdi)
Background.?A(H5N1) and A(H9N2) avian influenza viruses are enzootic in Egyptian poultry, and most A(H5N1) human cases since 2009 have occurred in Egypt. Our understanding of the epidemiology of avian ... Qi W, Su S, Xiao C, et al. Antibodies against H10N8 Avian Influenza Virus among Animal Workers in Guangdong Province before November 30, 2013, the First Recognized Human H10N8 Case. BMC Medicine 2014, 12:205. Abstract
submitted by kickingbird at Oct, 30, 2014 from BMC Medicine 2014, 12:205 (via http://www.biomedcentral.com/1741-7015/12/205/abstract)
BackgroundConsidered an epicenter of pandemic influenza virus generation, southern China has recently seen an increasing number of human H7N9 infections. However, it is not the only threat. On 30 November ... Wang XY, Chai CL, Li FD, He F, Yu Z, Wang XX, Shan. Epidemiology of human infections with avian influenza A(H7N9) virus in the two waves before and after October 2013 in Zhejiang province, China. Epidemiol Infect. 2014 Oct 7. Abstract
submitted by kickingbird at Oct, 12, 2014 from Epidemiol Infect. 2014 Oct 7 (via http://www.ncbi.nlm.nih.gov/pubmed/25286879)
We compared the epidemiological and clinical features of avian influenza A(H7N9) virus infections in the population in Zhejiang province, China, between March and April 2013 (first wave) and October 2013 ... CHIN AW, Li OT, Mok CK, Ng MK, et al. Influenza A viruses with different amino acid residues at PB2-627 display distinct replication properties in vitro and in vivo: Revealing the sequence plasticity of PB2-627 position. Virology. 2014 Sep 25;468-470C:545-555.. Abstract
submitted by kickingbird at Oct, 6, 2014 from Virology. 2014 Sep 25;468-470C:545-555. (via http://www.ncbi.nlm.nih.gov/pubmed/25262472)
Sequence analyses of influenza PB2 sequences indicate that the 627 position almost exclusively contains either lysine (K) or glutamic acid (E), suggesting a high sequence constraint at this genetic marker. ... TANG S, Li Y, Xia H, Huang J, et al. Improved methods for isolation of avian influenza virus. J Virol Methods. 2014 Sep 27. pii: S0166-0934. Abstract
submitted by kickingbird at Oct, 6, 2014 from J Virol Methods. 2014 Sep 27. pii: S0166-0934 (via http://www.ncbi.nlm.nih.gov/pubmed/25261812)
Isolation of viruses using chick embryos is a classical virological method. Inoculation of the allantoic cavity and use of allantoic fluid is a common method of passaging isolated avian influenza viruses. ... TAN L, Su S, Smith DK, He S, et al. A Combination of HA and PA Mutations Enhances Virulence in a Mouse-adapted H6N6 Influenza A Virus. J Virol. 2014 Oct 1. pii: JVI.01736-14. Abstract
submitted by kickingbird at Oct, 6, 2014 from J Virol. 2014 Oct 1. pii: JVI.01736-14 (via http://www.ncbi.nlm.nih.gov/pubmed/25275121)
H6N6 viruses are commonly isolated from domestic ducks and avian-to-swine transmissions of H6N6 viruses have been detected in China. Whether subsequent adaptation of H6N6 viruses in mammals would increase ... XU L, Bao L, Li F, Gu S, et al. Combinations of Oseltamivir and Fibrates Prolong the Mean Survival Time of Mice Infected with the Lethal H7N9 Influenza Virus.. J Gen Virol. 2014 Oct 1. pii: vir.0.069799-0.. Abstract
submitted by kickingbird at Oct, 6, 2014 from J Gen Virol. 2014 Oct 1. pii: vir.0.069799-0. (via http://www.ncbi.nlm.nih.gov/pubmed/25274854)
The outbreak of human infections caused by the novel avian-origin H7N9 influenza viruses in China since March 2013 underscores the urgent need to find an effective treatment strategy against H7N9 infection ... KAY AW, Fukuyama J, Aziz N, Dekker CL, et al. Enhanced natural killer-cell and T-cell responses to influenza A virus during pregnancy. Proc Natl Acad Sci U S A. 2014 Sep 22. Abstract
submitted by kickingbird at Sep, 30, 2014 from Proc Natl Acad Sci U S A. 2014 Sep 22 (via http://www.ncbi.nlm.nih.gov/pubmed/25246558)
Pregnant women experience increased morbidity and mortality after influenza infection, for reasons that are not understood. Although some data suggest that natural killer (NK)- and T-cell responses are ... COUZENS L, Gao J, Westgeest K, Sandbulte M, et al. An optimized enzyme-linked lectin assay to measure influenza A virus neuraminidase inhibition antibody titers in human sera. J Virol Methods. 2014 Sep 16.. Abstract
submitted by kickingbird at Sep, 30, 2014 from J Virol Methods. 2014 Sep 16. (via http://www.ncbi.nlm.nih.gov/pubmed/25233882)
Antibodies to neuraminidase (NA), the second most abundant surface protein on influenza virus, contribute toward protection against influenza. The traditional thiobarbituric acid (TBA) method to quantify ... MORALES-NEBREDA L, Chi M, Lecuona E, Chandel NS, e. Intratracheal administration of influenza virus is superior to intranasal administration as a model of acute lung injury. J Virol Methods. 2014 Sep 17. Abstract
submitted by kickingbird at Sep, 30, 2014 from J Virol Methods. 2014 Sep 17 (via http://www.ncbi.nlm.nih.gov/pubmed/25239366)
Infection of mice with human or murine adapted influenza A viruses results in a severe pneumonia. However, the results of studies from different laboratories show surprising variability, even in genetically ... FAN S, Hatta M, Kim JH, Le MQ, et al. Amino Acid Changes in the Influenza A Virus PA Protein that Attenuate Avian H5N1 Viruses in Mammals. J Virol. 2014 Sep 17. Abstract
submitted by kickingbird at Sep, 30, 2014 from J Virol. 2014 Sep 17 (via http://www.ncbi.nlm.nih.gov/pubmed/25231317)
The influenza viral polymerase complex affects host tropism and pathogenicity. In particular, several amino acids in the PB2 polymerase subunit are essential for the efficient replication of avian influenza ... CAO M, Wei C, Zhao L, Wang J, et al. DnaJA1/Hsp40 is co-opted by influenza A virus to enhance its viral RNA polymerase activity. J Virol. 2014 Sep 24. pii: JVI.02475. Abstract
submitted by kickingbird at Sep, 30, 2014 from J Virol. 2014 Sep 24. pii: JVI.02475 (via http://www.ncbi.nlm.nih.gov/pubmed/25253355)
The RNA-dependent RNA polymerase (RdRp) of influenza A virus is a heterotrimeric complex composed by PB1, PB2 and PA subunits. The interplay between host factors and the three subunits of the RdRp is critical ... LOVEDAY EK, Diederich S, Pasick J, Jean F, et al. Human microRNA-24 modulates highly pathogenic avian-origin H5N1 influenza A virus infection in A549 cells by targeting secretory pathway furin. J Gen Virol. 2014 Sep 18. Abstract
submitted by kickingbird at Sep, 30, 2014 from J Gen Virol. 2014 Sep 18 (via http://www.ncbi.nlm.nih.gov/pubmed/25234642)
A common critical cellular event many human enveloped viruses share is the requirement for proteolytic cleavage of the viral glycoprotein by furin in the host secretory pathway. For example, the furin-dependent ... LEON B, Ballesteros-Tato A, Randall TD, Lund FE, e. Prolonged antigen presentation by immune complex-binding dendritic cells programs the proliferative capacity of memory CD8 T cells. J Exp Med. 2014;211:1637-55. Abstract
submitted by kickingbird at Sep, 30, 2014 from J Exp Med. 2014;211:1637-55 (via http://www.ncbi.nlm.nih.gov/pubmed/25002751)
The commitment of naive CD8 T cells to effector or memory cell fates can occur after a single day of antigenic stimulation even though virus-derived antigens (Ags) are still presented by DCs long after ... YUAN XY, Wang YL, Yu KX, Zhang YX, et al. Isolation and genetic characterization of avian influenza virus H4N6 from ducks in China. Arch Virol. 2014 Sep 24. Abstract
submitted by kickingbird at Sep, 30, 2014 from Arch Virol. 2014 Sep 24 (via http://www.ncbi.nlm.nih.gov/pubmed/25248626)
An avian influenza virus (AIV) strain belonging to the H4 subtype and provisionally designated as A/duck/China/J1/2012(H4N6) was isolated from diseased ducks with respiratory disease at a commercial poultry ... SVANCAROVA P, Svetlikova D, Betakova T. Synergic and antagonistic effect of small hairpin RNAs targeting the NS gene of the influenza A virus in cells and mice. Virus Res. 2014 Sep 3. pii: S0168-1702. Abstract
submitted by kickingbird at Sep, 15, 2014 from Virus Res. 2014 Sep 3. pii: S0168-1702 (via http://www.ncbi.nlm.nih.gov/pubmed/25192613)
In the present study, we demonstrate the effect of individual and mixtures of shRNAs targeting the NS gene to treat an established infection of influenza A virus (IAV). We prepared 10 shRNAs targeting ... HILLAIRE ML, van Eijk M, Vogelzang-van Trierum SE,. Assessment of the antiviral properties of recombinant surfactant protein D against influenza B virus in vitro. Virus Res. 2014 Sep 5. Abstract
submitted by kickingbird at Sep, 15, 2014 from Virus Res. 2014 Sep 5 (via http://www.ncbi.nlm.nih.gov/pubmed/25200748)
The armamentarium of antiviral drugs against influenza viruses is limited. Furthermore, influenza viruses emerge that are resistant to existing antiviral drugs like the M2 and NA inhibitors. Therefore, ... CHENG K, Yu Z, Chai H, Sun W, et al. PB2-E627K and PA-T97I substitutions enhance polymerase activity and confer a virulent phenotype to an H6N1 avian influenza virus in mice. Virology. 2014 Sep 3;468-470C:207-213.. Abstract
submitted by kickingbird at Sep, 15, 2014 from Virology. 2014 Sep 3;468-470C:207-213. (via http://www.ncbi.nlm.nih.gov/pubmed/25194918)
H6N1 avian influenza viruses (AIVs) may pose a potential human risk as suggested by the first documented naturally-acquired human H6N1 virus infection in 2013. Here, we set out to elucidate viral determinants ... 5584 items, 20/Page, Page[195/280][|<<] [|<] [191] [192] [193] [194] [195] [196] [197] [198] [199] [200] [>|] [>>|] |
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