STANEKOVA Z, Adkins I, Kosova M, Janulikova J, et. Heterosubtypic protection against influenza induced by adenylate cyclase toxoids delivering conserved HA2 subunit of hemagglutinin. Antiviral Res. 2012 Oct 1. pii: S0166-3542(12)0020. Abstract
submitted by kickingbird at Oct, 14, 2012 from Antiviral Res. 2012 Oct 1. pii: S0166-3542(12)0020 (via http://www.ncbi.nlm.nih.gov/pubmed/23036818)
The protective efficacy of currently available influenza vaccines is restricted to vaccine strains and their close antigenic variants. A new strategy to obtain a cross-protection against influenza is based ... DIMMOCK NJ, Dove BK, Meng B, Scott PD, et al. Comparison of the protection of ferrets against pandemic 2009 influenza A virus (H1N1) by 244 DI influenza virus and oseltamivir. Antiviral Res. 2012 Oct 4. pii: S0166-3542(12)0022. Abstract
submitted by kickingbird at Oct, 14, 2012 from Antiviral Res. 2012 Oct 4. pii: S0166-3542(12)0022 (via http://www.ncbi.nlm.nih.gov/pubmed/23041142)
The main antivirals employed to combat seasonal and pandemic influenza are oseltamivir and zanamivir which act by inhibiting the virus-encoded neuraminidase. These have to be deployed close to the time ... UCHIDA Y, Suzuki Y, Shirakura M, Kawaguchi A, et a. Genetics and infectivity of H5N1 highly pathogenic avian influenza viruses isolated from chickens and wild birds in Japan during 2010-11. Virus Res. 2012 Sep 19. pii: S0168-1702(12)00322.. Abstract
submitted by kickingbird at Oct, 8, 2012 from Virus Res. 2012 Sep 19. pii: S0168-1702(12)00322. (via http://www.ncbi.nlm.nih.gov/pubmed/23000396)
Outbreaks of H5N1 subtype highly pathogenic avian influenza virus (HPAIV) were recorded in chickens, domesticated birds and wild birds throughout Japan from November 2010 to March 2011. Genetic analysis ... TAKASHITA E, Muraki Y, Sugawara K, Asao H, et al. Intrinsic Temperature Sensitivity of Influenza C Virus Hemagglutinin-Esterase-Fusion Protein. J Virol. 2012. Abstract
submitted by kickingbird at Oct, 8, 2012 from J Virol. 2012 (via http://www.ncbi.nlm.nih.gov/pubmed/23015703)
Influenza C virus replicates more efficiently at 33°C than at 37°C. To determine whether hemagglutinin-esterase-fusion protein (HEF), a surface glycoprotein of influenza C virus, is a restricting factor ... ZHU X, McBride R, Nycholat CM, Yu W, et al. Influenza virus neuraminidases with reduced enzymatic activity that avidly bind sialic acid receptors. J Virol. 2012. Abstract
submitted by kickingbird at Oct, 8, 2012 from J Virol. 2012 (via http://www.ncbi.nlm.nih.gov/pubmed/23015718)
Influenza neuraminidase (NA) cleaves off sialic acid from cellular receptors of hemagglutinin (HA) to enable progeny escape from infected cells. However, NA variants (D151G) of recent human H3N2 viruses ... HAYNES L, Szaba FM, Eaton SM, Kummer LW, et al. Immunity to the Conserved Influenza Nucleoprotein Reduces Susceptibility to Secondary Bacterial Infections. J Immunol. 2012. Abstract
submitted by kickingbird at Oct, 8, 2012 from J Immunol. 2012 (via http://www.ncbi.nlm.nih.gov/pubmed/23028058)
Influenza causes >250,000 deaths annually in the industrialized world, and bacterial infections frequently cause secondary illnesses during influenza outbreaks, including pneumonia, bronchitis, sinusitis, ... KANG HM, Choi JG, Kim KI, Park HY, et al. Genetic and antigenic characteristics of H4 subtype avian influenza viruses in Korea and their pathogenicity in quails, domestic ducks and mice. J Gen Virol. 2012. Abstract
submitted by kickingbird at Oct, 8, 2012 from J Gen Virol. 2012 (via http://www.ncbi.nlm.nih.gov/pubmed/23015746)
In Korea, a nationwide surveillance program has been implemented to identify highly pathogenic avian influenza virus since 2003. Avian influenza viruses (AIVs) belonging to one of the most common haemagglutinin ... YAMADA H, Moriishi E, Haredy AM, Takenaka N, et al. Influenza virus neuraminidase contributes to the dextran sulfate-dependent suppressive replication of some influenza A virus strains. Antiviral Res. 2012 Sep 26. pii: S0166-3542(12)002. Abstract
submitted by kickingbird at Oct, 8, 2012 from Antiviral Res. 2012 Sep 26. pii: S0166-3542(12)002 (via http://www.ncbi.nlm.nih.gov/pubmed/23022352)
Dextran sulfate (DS), a negatively charged, sulfated polysaccharide, suppresses the replication of an influenza A virus strain, and this suppression is associated with inhibition of the hemagglutinin (HA)-dependent ... LU X, Shi Y, Gao F, Xiao H, et al. Insights into avian influenza virus pathogenicity: the hemagglutinin precursor HA0 of H16 subtype has an alpha-helix structure in its cleavage site with an inefficient HA1/HA2 cleavage. J Virol. 2012. Abstract
submitted by kickingbird at Sep, 24, 2012 from J Virol. 2012 (via http://www.ncbi.nlm.nih.gov/pubmed/22993148)
With a new serotype (H17) hemagglutinin (HA) recently being discovered, there are now 17 serotypes (H1-H17) of influenza A viruses in total. It is believed that HA is initially expressed as a precursor ... AYLLON J, Russell RJ, Garcia-Sastre A, Hale BG, et. Contribution of NS1 effector domain dimerization to influenza A virus replication and virulence. J Virol. 2012. Abstract
submitted by kickingbird at Sep, 24, 2012 from J Virol. 2012 (via http://www.ncbi.nlm.nih.gov/pubmed/22993153)
Conserved tryptophan-187 facilitates homodimerization of the influenza A virus NS1 effector domain. We generated a mutant influenza virus expressing NS1-W187R to destabilize this self-interaction. NS1-W187R ... SCHLAUDECKER EP, McNeal MM, Dodd CN, Ranz JB, et a. Pregnancy Influences the Antibody Response to Trivalent Influenza Immunization. J Infect Dis. 2012. Abstract
submitted by kickingbird at Sep, 24, 2012 from J Infect Dis. 2012 (via http://www.ncbi.nlm.nih.gov/pubmed/22984116)
We report the immunogenicity of trivalent influenza immunization in 29 pregnant compared to 22 non-pregnant women. We obtained blood on day 0 prior to 2011-2012 influenza vaccine administration, and day ... CHO JH, Kim CD, Kim MS, Kang ES, et al. The impact of A(H1N1)pdm09 infection on renal transplant recipients: a multicenter cohort study. J Infect. 2012;65:88-90. Abstract
submitted by kickingbird at Sep, 24, 2012 from J Infect. 2012;65:88-90 (via http://www.ncbi.nlm.nih.gov/pubmed/22522290)
2009 H1N1 influenza infection in cancer patients and hematopoietic stem cell transplant recipients. NELSON M, Detmer SE, Wentworth DE, Tan Y, et al. Genomic reassortment of influenza A virus in North American swine, 1998-2011. J Gen Virol. 2012.. Abstract
submitted by kickingbird at Sep, 24, 2012 from J Gen Virol. 2012. (via http://www.ncbi.nlm.nih.gov/pubmed/22993190)
Revealing the frequency and determinants of reassortment among RNA genome segments is fundamental to understanding basic aspects of the biology and evolution of the influenza virus. To estimate the extent ... SMIEJA M. Review: Oseltamivir relieves symptoms but does not reduce hospitalizations in influenza. Ann Intern Med. 2012;157:JC3-5. Abstract
submitted by kickingbird at Sep, 24, 2012 from Ann Intern Med. 2012;157:JC3-5 (via http://www.ncbi.nlm.nih.gov/pubmed/22986397)
QUESTIONS Are neuraminidase inhibitors effective for preventing or treating influenza in adults and children who are not immunocompromised? What are the harms? REVIEW SCOPE Included studies compared neuraminidase ... Taubenberger JK, et al.. Reconstruction of the 1918 Influenza Virus: Unexpected Rewards from the Past. mBio 3(5):e00201-12. doi:10.1128/mBio.00201-12.. Abstract
submitted by kickingbird at Sep, 15, 2012 from mBio 3(5):e00201-12. doi:10.1128/mBio.00201-12. (via http://mbio.asm.org:80/content/3/5/e00201-12)
The influenza pandemic of 1918–1919 killed approximately 50 million people. The unusually severe morbidity and mortality associated with the pandemic spurred physicians and scientists to isolate the etiologic ... KOWALCZYK A, Markowska-Daniel I, Rasmussen TB. Development of a primer-probe energy transfer based real-time PCR for the detection of Swine Influenza Virus. J Virol Methods. 2012. Abstract
submitted by kickingbird at Sep, 10, 2012 from J Virol Methods. 2012 (via http://www.ncbi.nlm.nih.gov/pubmed/22944078)
Swine influenza virus (SIV) causes a contagious and requiring official notification disease of pigs and humans. In this study, a real-time reverse transcription-polymerase chain reaction (RT-PCR) assay ... EDENBOROUGH KM, Gilbertson BP, Brown LE. A mouse model for the study of contact-dependent transmission of influenza A virus and the factors that govern transmissibility. J Virol. 2012. Abstract
submitted by kickingbird at Sep, 10, 2012 from J Virol. 2012 (via http://www.ncbi.nlm.nih.gov/pubmed/22951824)
Influenza A virus transmission by direct contact is not well characterized. Here we describe a mouse model for investigation of factors regulating contact-dependent transmission. Strains within the H3N2 ... LI W, Moltedo B, Moran TM.. Type I IFN induction during influenza infection increases the susceptibility to secondary S. pneumoniae Infection by negative regulation of gammadelta T cells. J Virol. 2012. Abstract
submitted by kickingbird at Sep, 10, 2012 from J Virol. 2012 (via http://www.ncbi.nlm.nih.gov/pubmed/22951826)
The majority of deaths following influenza infection result from secondary bacterial superinfection, most commonly caused by Streptococcus pneumoniae. Several models have been proposed to explain how primary ... SHI M, Jagger BW, Wise HM, Digard P, et al. Evolutionary conservation of the PA-X open reading frame in segment 3 of influenza A virus. J Virol. 2012. Abstract
submitted by kickingbird at Sep, 10, 2012 from J Virol. 2012 (via http://www.ncbi.nlm.nih.gov/pubmed/22951836)
PA-X is a fusion protein of influenza A virus encoded in part from a +1 frameshifted 'X-ORF' in segment 3. We show that the X-ORF of diverse influenza A viruses can be divided into two groups that differ ... VAN WIELINK R, Harmsen MM, Martens DE, Peeters BP,. Mutations in the M gene segment can substantially increase replication efficiency of NS1 deletion influenza A virus in MDCK cells. J Virol. 2012. Abstract
submitted by kickingbird at Sep, 10, 2012 from J Virol. 2012 (via http://www.ncbi.nlm.nih.gov/pubmed/22951840)
Influenza viruses unable to express NS1 protein (delNS1) replicate poorly and induce high amounts of interferon (IFN). They are therefore considered as candidate viruses for live-attenuated influenza vaccines. ... 5154 items, 20/Page, Page[195/258][|<<] [|<] [191] [192] [193] [194] [195] [196] [197] [198] [199] [200] [>|] [>>|] |
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