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2024-4-24 16:14:54
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GARG S, Moore Z, Lee N, McKenna J, et al.. A Cluster of Patients Infected with I221V Influenza B Virus Variants with Reduced Oseltamivir Susceptibility--North Carolina and South Carolina, 2010-2011. J Infect Dis. 2012.  Abstract  
submitted by kickingbird at Jan, 2, 2013 from J Infect Dis. 2012 (via http://www.ncbi.nlm.nih.gov/pubmed/23242536)
Background.?During 2010-2011, influenza B viruses with a novel neuraminidase substitution, denoted I221V, (B/I221V) associated with reduced in vitro oseltamivir susceptibility were detected in North Carolina ...

TAKAYAMA I, Nakauchi M, Fujisaki S, Odagiri T, et. Rapid detection of the S247N neuraminidase mutation in influenza A(H1N1)pdm09 virus by one-step duplex RT-PCR assay. J Virol Methods. 2012 Dec 19. pii: S0166-0934(12)0.  Abstract  
submitted by kickingbird at Jan, 2, 2013 from J Virol Methods. 2012 Dec 19. pii: S0166-0934(12)0 (via http://www.ncbi.nlm.nih.gov/pubmed/23261798)
Neuraminidase inhibitors, especially oseltamivir, have been used worldwide for the prophylaxis or treatment of pandemic influenza H1N1 2009 (A(H1N1)pdm09) viruses. The most commonly detected oseltamivir-resistant ...

NGUYEN TT, Kwon HJ, Kim IH, Hong SM, et al. Multiplex nested RT-PCR for detecting avian influenza virus, infectious bronchitis virus and Newcastle disease virus. J Virol Methods. 2012 Dec 19. pii: S0166-0934(12)0.  Abstract  
submitted by kickingbird at Jan, 2, 2013 from J Virol Methods. 2012 Dec 19. pii: S0166-0934(12)0 (via http://www.ncbi.nlm.nih.gov/pubmed/23261801)
In this study, multiplex nested RT-PCR (mnRT-PCR) was applied to simultaneous detect multiplex PCR with the higher sensitivity of nested PCR that is required for avian influenza, infectious bronchitis ...

SUN Y, Tan Y, Wei K, Sun H, et al. Amino acid 316 of hemagglutinin and the neuraminidase stalk length influence virulence of H9N2 influenza virus in chickens and mice. J Virol. 2012.  Abstract  
submitted by kickingbird at Jan, 2, 2013 from J Virol. 2012 (via http://www.ncbi.nlm.nih.gov/pubmed/23269805)
H9N2 influenza viruses with an A316S substitution in hemagglutinin (HA) and a shorter neuraminidase (NA) stalk have become predominant in China. The A316S was shown to increase HA cleavage efficiency when ...

WANG D, Sleeman K, Huang W, Nguyen HT, et al. Neuraminidase Inhibitor Susceptibility Testing of Influenza Type B Viruses in China during 2010 and 2011 Identifies Viruses with Reduced Susceptibility to Oseltamivir and Zanamivir. Antiviral Res. 2012 Dec 22. pii: S0166-3542(12)002.  Abstract  
submitted by kickingbird at Jan, 2, 2013 from Antiviral Res. 2012 Dec 22. pii: S0166-3542(12)002 (via http://www.ncbi.nlm.nih.gov/pubmed/23267831)
Influenza type B viruses are responsible for substantial morbidity and mortality in humans. Antiviral drugs are an important supplement to vaccination for reducing the public health impact of influenza ...

Younan M, Poh MK, Elassal E, Davis T, Rivailler P,. Microevolution of Highly Pathogenic Avian Influenza A(H5N1) Viruses Isolated from Humans, Egypt, 2007–2011. Emerg Infect Dis. 2013 Jan.  Abstract  
submitted by kickingbird at Dec, 16, 2012 from Emerg Infect Dis. 2013 Jan (via http://wwwnc.cdc.gov:80/eid/article/19/1/12-1080_article.htm)
We analyzed highly pathogenic avian influenza A(H5N1) viruses isolated from humans infected in Egypt during 2007–2011. All analyzed viruses evolved from the lineage of subtype H5N1 viruses introduced into ...

SU S, Qi W, Chen J, Zhu W, et al. Seroepidemiological Evidence of Avian Influenza A Virus Transmission to Pigs in Southern China. J Clin Microbiol. 2012.  Abstract  
submitted by kickingbird at Dec, 3, 2012 from J Clin Microbiol. 2012 (via http://www.ncbi.nlm.nih.gov/pubmed/23175250)
Recently, three novel avian-origin swine influenza viruses (SIVs) were first isolated from pigs in Guangdong Province, southern China, yet little is known about the seroprevalence of avian influenza among ...

HAMILTON BS, Sun X, Chung C, Whittaker GR, et al. Acquisition of a novel eleven amino acid insertion directly N-terminal to a tetrabasic cleavage site confers intracellular cleavage of an H7N7 influenza virus hemagglutinin. Virology. 2012 Oct 7. pii: S0042-6822(12)00445.  Abstract  
submitted by kickingbird at Oct, 14, 2012 from Virology. 2012 Oct 7. pii: S0042-6822(12)00445 (via http://www.ncbi.nlm.nih.gov/pubmed/23051710)
A critical feature of highly pathogenic avian influenza viruses (H5N1 and H7N7) is the efficient intracellular cleavage of the hemagglutinin (HA) protein. H7N7 viruses also exist in equine species, and ...

WANG B, Chen Q, Chen Z.. Complete Genome Sequence of an H9N2 Avian Influenza Virus Isolated from Egret in Lake Dongting Wetland.. J Virol. 2012;86:11939.  Abstract  
submitted by kickingbird at Oct, 14, 2012 from J Virol. 2012;86:11939 (via http://www.ncbi.nlm.nih.gov/pubmed/23043171)
We isolated a recombinant H9N2 avian influenza virus (AIV) from fresh egret feces in the Ardeidae protection region of the Dongting Lake wetland area in China, and it was designated A/Egret/Hunan/1/2012(H9N2). ...

TENG Q, Hu T, Li X, Li G, et al. Complete Genome Sequence of an H3N2 Avian Influenza Virus Isolated from a Live Poultry Market in Eastern China. J Virol. 2012;86:11944.  Abstract  
submitted by kickingbird at Oct, 14, 2012 from J Virol. 2012;86:11944 (via http://www.ncbi.nlm.nih.gov/pubmed/23043175)
Previous studies indicate that the H3 influenza virus has the ability to establish infection upon interspecies transmission and poses a threat to mammals. Therefore, it is important to enhance the surveillance ...

CHEN C, Zhao G, Gu X, Gu M, et al. Complete Genomic Sequence of a Novel Reassortant H11N3 Influenza Virus Isolated from Domestic Ducks in Jiangsu, China. J Virol. 2012;86:11950-1.  Abstract  
submitted by kickingbird at Oct, 14, 2012 from J Virol. 2012;86:11950-1 (via http://www.ncbi.nlm.nih.gov/pubmed/23043179)
For the first time we report the complete genomic sequence of an H11N3 influenza virus from domestic ducks in China. Phylogenetic analysis showed that the H11N3 virus was a novel reassortant with its genes ...

TENG Q, Ji X, Li G, Li X, et al. Complete Genome Sequences of a Novel Reassortant H4N2 Avian Influenza Virus Isolated from a Live Poultry Market in Eastern China. J Virol. 2012;86:11952.  Abstract  
submitted by kickingbird at Oct, 14, 2012 from J Virol. 2012;86:11952 (via http://www.ncbi.nlm.nih.gov/pubmed/23043180)
A/duck/Shanghai/28-1/2009(H4N2) (DK28) was isolated from a live poultry market in Shanghai, China. Using PCR and sequencing analysis, we obtained the complete genome sequences of the DK28 virus. The sequence ...

HSU WB, Shih JL, Shih JR, Du JL, et al. Cellular Protein HAX1 Interacts With Influenza A Virus Polymerase PA Subunit and Impedes Its Nuclear Translocation. J Virol. 2012.  Abstract  
submitted by kickingbird at Oct, 14, 2012 from J Virol. 2012 (via http://www.ncbi.nlm.nih.gov/pubmed/23055567)
Transcription and replication of the influenza A virus RNA genome occurs in the nucleus through the viral RNA-dependent RNA polymerase consisting of PB1, PB2, and PA. Cellular factors that associate with ...

SAKABE S, Takano R, Nagamura-Inoue T, Yamashita N,. Differences in Cytokine Production in Human Macrophages and in Virulence in Mice Are Attributable to the Acidic Polymerase Protein of Highly Pathogenic Influenza A Virus Subtype H5N1. J Infect Dis. 2012.  Abstract  
submitted by kickingbird at Oct, 14, 2012 from J Infect Dis. 2012 (via http://www.ncbi.nlm.nih.gov/pubmed/23042757)
BackgroundThe pathogenesis of influenza A virus subtype H5N1 (hereafter, "H5N1") infection in humans is not completely understood, although hypercytokinemia is thought to play a role. We previously reported ...

WU P, Goldstein E, Ho LM, Yang L, et al.. Excess mortality associated with influenza A and B virus in Hong Kong, 1998-2009. J Infect Dis. 2012.  Abstract  
submitted by kickingbird at Oct, 14, 2012 from J Infect Dis. 2012 (via http://www.ncbi.nlm.nih.gov/pubmed/23045622)
While deaths associated with laboratory-confirmed influenza virus infections are rare, the excess mortality burden of influenza estimated from statistical models may more reliably quantify the impact of ...

TAKANO R, Kiso M, Igarashi M, Le QM, et al. Molecular mechanisms underlying oseltamivir resistance mediated by an I117V substitution in the NA of H5N1 avian influenza viruses. J Infect Dis. 2012.  Abstract  
submitted by kickingbird at Oct, 14, 2012 from J Infect Dis. 2012 (via http://www.ncbi.nlm.nih.gov/pubmed/23053629)
The neuraminidase (NA) inhibitor oseltamivir is widely used to treat patients infected with influenza viruses. An Ile-to-Val change at position 117 in H5N1 NA (NA-I117V) confers a reduction in susceptibility ...

SOUBIES SM, Hoffmann TW, Croville G, Larcher T, et. Deletion of the C-terminal ESEV domain of NS1 does not affect the replication of a low-pathogenic avian influenza virus H7N1 in ducks and chickens. J Gen Virol. 2012.  Abstract  
submitted by kickingbird at Oct, 14, 2012 from J Gen Virol. 2012 (via http://www.ncbi.nlm.nih.gov/pubmed/23052391)
Highly pathogenic avian influenza (HPAI) H7N1 viruses caused a series of epizootics in Italy between 1999 and 2001. The emergence of these HPAI viruses coincided with the deletion of the six amino acids ...

YAO Y, Wang H, Chen Q, Zhang H, et al. Characterization of low-pathogenic H6N6 avian influenza viruses in central China. Arch Virol. 2012.  Abstract  
submitted by kickingbird at Oct, 14, 2012 from Arch Virol. 2012 (via http://www.ncbi.nlm.nih.gov/pubmed/23053524)
Three strains of H6N6 subtype avian influenza virus (AIV) were isolated from live-poultry markets of central China during 2009-2010. A phylogenetic analysis showed that these isolates originated from gene ...

BUI VN, Ogawa H, Ngo LH, Baatartsogt T, et al. H5N1 highly pathogenic avian influenza virus isolated from conjunctiva of a whooper swan with neurological signs. Arch Virol. 2012.  Abstract  
submitted by kickingbird at Oct, 14, 2012 from Arch Virol. 2012 (via http://www.ncbi.nlm.nih.gov/pubmed/23053526)
An H5N1 highly pathogenic avian influenza virus was isolated from conjunctiva of a whooper swan with neurological signs, which was captured during the latest H5N1 HPAI outbreak in Japan. The conjunctival ...

STANEKOVA Z, Adkins I, Kosova M, Janulikova J, et. Heterosubtypic protection against influenza induced by adenylate cyclase toxoids delivering conserved HA2 subunit of hemagglutinin. Antiviral Res. 2012 Oct 1. pii: S0166-3542(12)0020.  Abstract  
submitted by kickingbird at Oct, 14, 2012 from Antiviral Res. 2012 Oct 1. pii: S0166-3542(12)0020 (via http://www.ncbi.nlm.nih.gov/pubmed/23036818)
The protective efficacy of currently available influenza vaccines is restricted to vaccine strains and their close antigenic variants. A new strategy to obtain a cross-protection against influenza is based ...

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