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2024-11-22 9:20:35
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Valerie Le Sage, etc.,al. [preprint]Influenza H5N1 and H1N1 viruses remain infectious in unpasteurized milk on milking machinery surfaces. https://doi.org/10.1101/2024.05.22.24307745.  Abstract  
submitted by kickingbird at May, 25, 2024 from https://doi.org/10.1101/2024.05.22.24307745 (via https://www.medrxiv.org/content/10.1101/2024.05.22.24307745v)
Spillover of highly pathogenic avian H5N1 into the cattle population poses a risk to humans through the close contact with farm workers. High viral loads of influenza viruses in the unpasteurized milk ...

Jinyu Huang, Kaixiong Ma, Jiahao Zhang, Jiangtao Z. Pathogenicity and Transmission of Novel Highly Pathogenic H7N2 Variants Originating from H7N9 Avian Influenza Viruses in Chickens. Virology, 2024.  Abstract  
submitted by kickingbird at May, 25, 2024 from Virology, 2024 (via https://www.sciencedirect.com/science/article/abs/pii/S00426)
The H7 subtype avian influenza viruses are circulating widely worldwide, causing significant economic losses to the poultry industry and posing a serious threat to human health. In 2019, H7N2 and H7N9 ...

Nguyen, T.H.O., Rowntree, L.C., Chua, B.Y. et al. Defining the balance between optimal immunity and immunopathology in influenza virus infection. Nat Rev Immunol (2024).  Abstract  
submitted by kickingbird at May, 25, 2024 from Nat Rev Immunol (2024) (via https://link.springer.com/article/10.1038/s41577-024-01029-1)
Influenza A viruses remain a global threat to human health, with continued pandemic potential. In this Review, we discuss our current understanding of the optimal immune responses that drive recovery from ...

Ulupinar, P., ?a?layan, E., Rayaman, E. et al. The mitochondrial carrier homolog 2 is involved in down-regulation of influenza A virus replication. Mol Biol Rep 51, 642 (2024).  Abstract  
submitted by kickingbird at May, 25, 2024 from Mol Biol Rep 51, 642 (2024) (via https://link.springer.com/article/10.1007/s11033-024-09584-5)
BackgroundThe mitochondrial carrier homolog 2 (MTCH2) is a mitochondrial outer membrane protein regulating mitochondrial metabolism and functions in lipid homeostasis and apoptosis. Experimental data on ...

Li, J., Nie, L. Global Dynamics Analysis of Non-Local Delayed Reaction-Diffusion Avian Influenza Model with Vaccination and Multiple Transmission Routes in the Spatial Heterogeneous Environment. Theory Dyn. Syst. 23, 198 (2024).  Abstract  
submitted by kickingbird at May, 25, 2024 from Theory Dyn. Syst. 23, 198 (2024) (via https://link.springer.com/article/10.1007/s12346-024-01057-1)
In order to reveal the transmission dynamics of Avian influenza and explore effective control measures, we develop a non-local delayed reaction-diffusion model of Avian influenza with vaccination and multiple ...

Falcón A, Martínez-Pulgarín S, López-Serrano S, Re. Development of a Fully Protective Pandemic Avian Influenza Subunit Vaccine in Insect Pupae. Viruses. 2024; 16(6):829.  Abstract  
submitted by kickingbird at May, 25, 2024 from Viruses. 2024; 16(6):829 (via https://www.mdpi.com/1999-4915/16/6/829)
In this study, we pioneered an alternative technology for manufacturing subunit influenza hemagglutinin (HA)-based vaccines. This innovative method involves harnessing the pupae of the Lepidoptera Trichoplusia ...

Poulson RL, Reeves AB, Ahlstrom CA, Scott LC, Hubb. Infectivity of Wild-Bird Origin Influenza A Viruses in Minnesota Wetlands across Seasons. Pathogens. 2024 May 14;13(5):406.  Abstract  
submitted by kickingbird at May, 25, 2024 from Pathogens. 2024 May 14;13(5):406 (via https://www.mdpi.com/2076-0817/13/5/406)
The environmental tenacity of influenza A viruses (IAVs) in the environment likely plays a role in their transmission; IAVs are able to remain infectious in aquatic habitats and may have the capacity to ...

WHO team. Genetic and antigenic characteristics of clade 2.3.4.4b A(H5N1) viruses identified in dairy cattle in the United States of America. WHO.  Abstract  
submitted by kickingbird at May, 24, 2024 from WHO (via https://www.who.int/publications/m/item/genetic-and-antigeni)
During 2020, highly pathogenic avian influenza A(H5N1) viruses of clade 2.3.4.4b emerged and rapidly spread across many parts of Africa, Asia and Europe. In late 2021, the 2.3.4.4b A(H5N1) viruses were ...

Schwab LSU, Do THT, Pilapitiya D, Koutsakos M. Dissemination of influenza B virus to the lower respiratory tract of mice is restricted by the interferon response. J Virol. 2024 May 23:e0160423.  Abstract  
submitted by kickingbird at May, 24, 2024 from J Virol. 2024 May 23:e0160423 (via https://journals.asm.org/doi/10.1128/jvi.01604-23)
The global burden of disease caused by influenza B virus (IBV) is substantial; however, IBVs remain overlooked. Understanding host-pathogen interactions and establishing physiologically relevant models ...

Brown JD, Black A, Haman KH, Diel DG, Ramirez VE,. Antibodies to Influenza A(H5N1) Virus in Hunting Dogs Retrieving Wild Fowl, Washington, USA. Emerg Infect Dis. 2024 Jun;30(6):1271-1274.  Abstract  
submitted by kickingbird at May, 24, 2024 from Emerg Infect Dis. 2024 Jun;30(6):1271-1274 (via https://wwwnc.cdc.gov/eid/article/30/6/23-1459_article)
We detected antibodies to H5 and N1 subtype influenza A viruses in 4/194 (2%) dogs from Washington, USA, that hunted or engaged in hunt tests and training with wild birds. Historical data provided by dog ...

Giulia Graziosi, Caterina Lupini, Francesco Dalla. Characterizing the domestic-wild bird interface through camera traps in an area at risk for avian influenza introduction in Northern Italy. Poultry ScienceAvailable online 23 May 2024.  Abstract  
submitted by kickingbird at May, 24, 2024 from Poultry ScienceAvailable online 23 May 2024 (via https://www.sciencedirect.com/science/article/pii/S003257912)
Direct or indirect interactions between sympatric wildlife and poultry can lead to interspecies disease transmission. Particularly, avian influenza (AI) is a viral epidemic disease for which the poultry-wild ...

Leonardo C Caserta, etc.,al. [preprint]From birds to mammals: spillover of highly pathogenic avian influenza H5N1 virus to dairy cattle led to efficient intra- and interspecies transmission. https://doi.org/10.1101/2024.05.22.595317.  Abstract  
submitted by kickingbird at May, 23, 2024 from https://doi.org/10.1101/2024.05.22.595317 (via https://www.biorxiv.org/content/10.1101/2024.05.22.595317v1)
Infections with the highly pathogenic avian influenza (HPAI) H5N1 clade 2.3.4.4b virus have resulted in the death of millions of domestic birds and thousands of wild birds in the U.S. since January, 2022. ...

Oltean T, Maelfait J, Saelens X. Need for standardization of Influenza A virus-induced cell death in vivo to improve consistency of inter-laboratory research findings. Cell Death Discov. 2024 May 22;10(1):247.  Abstract  
submitted by kickingbird at May, 23, 2024 from Cell Death Discov. 2024 May 22;10(1):247 (via https://www.nature.com/articles/s41420-024-01981-w)
The involvement of necroptosis in the control of influenza A virus (IAV) infection has been reported in multiple studies. Downstream of the nucleic acid sensor ZBP1, RIPK3 kinase activity is critically ...

Spronken, M.I., Funk, M., Gultyaev, A.P. et al. Nucleotide sequence as key determinant driving insertions at influenza A virus hemagglutinin cleavage sites. npj Viruses 2, 17 (2024).  Abstract  
submitted by kickingbird at May, 22, 2024 from npj Viruses 2, 17 (2024) (via https://www.nature.com/articles/s44298-024-00029-1)
Highly pathogenic avian influenza viruses (HPAIVs) emerge from H5 and H7 low pathogenic avian influenza viruses (LPAIVs), most frequently upon insertions of nucleotides coding for basic amino acids at ...

Shalaby S, Awadin W, Manzoor R, Karam R, Mohamadin. Pathological and phylogenetic characteristics of fowl AOAV-1 and H5 isolated from naturally infected Meleagris Gallopavo. BMC Vet Res. 2024 May 21;20(1):216.  Abstract  
submitted by kickingbird at May, 22, 2024 from BMC Vet Res. 2024 May 21;20(1):216 (via https://bmcvetres.biomedcentral.com/articles/10.1186/s12917-)
Background: In this study, we investigated the prevalence of respiratory viruses in four Hybrid Converter Turkey (Meleagris gallopavo) farms in Egypt. The infected birds displayed severe respiratory signs, ...

Deblanc C, Quéguiner S, Gorin S, Richard G, Moro A. Pathogenicity and escape to pre-existing immunity of a new genotype of swine influenza H1N2 virus that emerged in France in 2020. Vet Res. 2024 May 21;55(1):65.  Abstract  
submitted by kickingbird at May, 22, 2024 from Vet Res. 2024 May 21;55(1):65 (via https://veterinaryresearch.biomedcentral.com/articles/10.118)
In 2020, a new genotype of swine H1N2 influenza virus (H1avN2-HA 1C.2.4) was identified in France. It rapidly spread within the pig population and supplanted the previously predominant H1avN1-HA 1C.2.1 ...

Li S, Xiao W, Li H, Hu D, Li K, Chen Q, Liu G, Yan. Identification of neurological complications in childhood influenza: a random forest model. BMC Pediatr. 2024 May 20;24(1):347.  Abstract  
submitted by kickingbird at May, 22, 2024 from BMC Pediatr. 2024 May 20;24(1):347 (via https://bmcpediatr.biomedcentral.com/articles/10.1186/s12887)
Background: Among the neurological complications of influenza in children, the most severe is acute necrotizing encephalopathy (ANE), with a high mortality rate and neurological sequelae. ANE is characterized ...

Feoktistova S, Degtyarev E, Abramov I, Artemyev V,. The complete coding sequence of Influenza A/Unknown/Chelyabinsk/206/H7N4. Microbiol Resour Announc. 2024 May 20:e0031224.  Abstract  
submitted by kickingbird at May, 21, 2024 from Microbiol Resour Announc. 2024 May 20:e0031224 (via https://journals.asm.org/doi/10.1128/mra.00312-24)
An influenza virus strain was obtained during a bird surveillance study in 2023 near Lake Chebarkul in the Chelyabinsk region, Russia. This complete coding genome sequence of the virus sampled from the ...

Yusheng Jia, etc.,al. Revealing novel and conservative T-cell epitopes with MHC B2 restriction on H9N2 Avian Influenza Virus (AIV). Journal of Biological ChemistryAvailable online 19.  Abstract  
submitted by kickingbird at May, 21, 2024 from Journal of Biological ChemistryAvailable online 19 (via https://www.sciencedirect.com/science/article/pii/S002192582)
B2 haplotype MHC has been extensively reported to confer resistance to various avian diseases. But its peptide-binding motif is unknown and the presenting peptide is rarely identified. Here, we identified ...

Kieran TJ, Sun X, Creager HM, Tumpey TM, Maines TR. An aggregated dataset of serial morbidity and titer measurements from influenza A virus-infected ferrets. Sci Data. 2024 May 17;11(1):510.  Abstract  
submitted by kickingbird at May, 19, 2024 from Sci Data. 2024 May 17;11(1):510 (via https://www.nature.com/articles/s41597-024-03256-6)
Data from influenza A virus (IAV) infected ferrets provides invaluable information towards the study of novel and emerging viruses that pose a threat to human health. This gold standard model can recapitulate ...

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