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2024-11-24 1:37:58
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LYOO KS, Na W, Yeom M, Jeong DG, et al. Virulence of a novel reassortant canine H3N2 influenza virus in ferret, dog and mouse models. Arch Virol. 2016 Apr 30..  Abstract  
submitted by kickingbird at May, 8, 2016 from Arch Virol. 2016 Apr 30. (via http://www.ncbi.nlm.nih.gov/pubmed/27138550)
An outbreak of a canine influenza virus (CIV) H3N2 reassortant derived from pandemic (pdm) H1N1 and CIV H3N2 in companion animals has underscored the urgent need to monitor CIV infections for potential ...

J Virol. 2016 Apr 27. pii: JVI.00410. Rearrangement of influenza virus spliced segments for the development of live attenuated vaccines.. J Virol. 2016 Apr 27. pii: JVI.00410-16.  Abstract  
submitted by kickingbird at May, 1, 2016 from J Virol. 2016 Apr 27. pii: JVI.00410-16 (via http://www.ncbi.nlm.nih.gov/pubmed/27122587)
Influenza viral infections represent a serious public health problem, causing a contagious respiratory disease, which is most effectively prevented through vaccination. Segments seven (M) and eight (NS) ...

JIANG J, Li J, Fan W, Zheng W, et al. Robust Lys63-linked Ubiquitination of RIG-I Promotes Cytokine Eruption in Early Influenza B Virus Infection. J Virol. 2016 Apr 27. pii: JVI.00549-16.  Abstract  
submitted by kickingbird at May, 1, 2016 from J Virol. 2016 Apr 27. pii: JVI.00549-16 (via http://www.ncbi.nlm.nih.gov/pubmed/27122586)
Influenza A and B virus infections both cause a host innate immunity response. Here, we report that the robust production of type I and III interferons (IFNs), IFN-stimulated genes, and pre-inflammatory ...

SUN H, Pu J, Wei Y, Sun Y, et al. Highly pathogenic avian influenza H5N6 viruses exhibit enhanced affinity for human type sialic acid receptor and in-contact transmission in model ferrets. J Virol. 2016 Apr 27. pii: JVI.00127-16..  Abstract  
submitted by kickingbird at May, 1, 2016 from J Virol. 2016 Apr 27. pii: JVI.00127-16. (via http://www.ncbi.nlm.nih.gov/pubmed/27122581)
Since May 2014, highly pathogenic avian influenza (HPAI) H5N6 virus has been reported to cause six severe human infections three of which were fatal. The biological properties of this subtype, in particular ...

SONG MS, Baek YH, Pascua PN, Kwon HI, et al. Growth and Pathogenic Potential of Naturally Selected Reassortants after Coinfection with Pandemic H1N1 and Highly Pathogenic Avian Influenza H5N1 Viruses. J Virol. 2015;90:616-23.  Abstract  
submitted by kickingbird at May, 1, 2016 from J Virol. 2015;90:616-23 (via http://www.ncbi.nlm.nih.gov/pubmed/26491154)
Coinfection of ferrets with H5N1 and pH1N1 viruses resulted in two predominate genotypes in the lungs containing surface genes of highly pathogenic avian influenza H5N1 virus in the backbone of pandemic ...

BERTRAN K, Swayne DE, Pantin-Jackwood MJ, Kapczyns. Lack of chicken adaptation of newly emergent Eurasian H5N8 and reassortant H5N2 high pathogenicity avian influenza viruses in the U.S. is consistent with restricted poultry outbreaks in the Pacific fl. Virology. 2016;494:190-197.  Abstract  
submitted by kickingbird at May, 1, 2016 from Virology. 2016;494:190-197 (via http://www.ncbi.nlm.nih.gov/pubmed/27110710)
In 2014-2015, the U.S. experienced an unprecedented outbreak of Eurasian clade 2.3.4.4 H5 highly pathogenic avian influenza (HPAI) virus, initially affecting mainly wild birds and few backyard and commercial ...

LIU WC, Lin YL, Spearman M, Cheng PY, et al. Influenza Hemagglutinin Glycoproteins with Different N-glycan Patterns Activate Dendritic Cells in Vitro. J Virol. 2016 Apr 20. pii: JVI.00452-16..  Abstract  
submitted by kickingbird at Apr, 28, 2016 from J Virol. 2016 Apr 20. pii: JVI.00452-16. (via http://www.ncbi.nlm.nih.gov/pubmed/27099319)
Influenza HA N-glycans serve important regulatory roles in the control of virus virulence, antigenicity, receptor-binding specificity, and viral immune escape. Considered essential for controlling innate ...

FUDO S, Yamamoto N, Nukaga M, Odagiri T, et al. Two Distinctive Binding Modes of Endonuclease Inhibitors to the N-Terminal Region of Influenza Virus Polymerase Acidic Subunit. Biochemistry. 2016 Apr 26.  Abstract  
submitted by kickingbird at Apr, 28, 2016 from Biochemistry. 2016 Apr 26 (via http://www.ncbi.nlm.nih.gov/pubmed/27088785)
Influenza viruses are global threat to humans, and the development of new antiviral agents are still demanded to prepare for pandemics and to overcome the emerging resistance to the current drugs. Influenza ...

WU H, Lu R, Peng X, Peng X, et al. Isolation and genetic characterization of novel reassortant H6N6 subtype avian influenza viruses isolated from chickens in eastern China. Arch Virol. 2016 Apr 21..  Abstract  
submitted by kickingbird at Apr, 28, 2016 from Arch Virol. 2016 Apr 21. (via http://www.ncbi.nlm.nih.gov/pubmed/27101069)
H6 subtype avian influenza viruses (AIVs) possess the ability to cross the species barrier to infect mammals and pose a threat to human health. From June 2014 to July 2015, 12 H6N6 AIVs were isolated from ...

M.C.W.Chan, etc.,al. Human mesenchymal stromal cells reduce influenza A H5N1-associated acute lung injury in vitro and in vivo. PNAS 2016 ; published ahead of print March 14, 201.  Abstract  
submitted by kickingbird at Mar, 29, 2016 from PNAS 2016 ; published ahead of print March 14, 201 (via http://www.pnas.org/content/early/2016/03/09/1601911113)
Influenza can cause acute lung injury. Because immune responses often play a role, antivirals may not ensure a successful outcome. To identify pathogenic mechanisms and potential adjunctive therapeutic ...

SONG MS, Kumar G, Shadrick WR, Zhou W, et al. Identification and characterization of influenza variants resistant to a viral endonuclease inhibitor. Proc Natl Acad Sci U S A. 2016 Mar 14. pii: 201519.  Abstract  
submitted by kickingbird at Mar, 21, 2016 from Proc Natl Acad Sci U S A. 2016 Mar 14. pii: 201519 (via http://www.ncbi.nlm.nih.gov/pubmed/26976575)
The influenza endonuclease is an essential subdomain of the viral RNA polymerase. It processes host pre-mRNAs to serve as primers for viral mRNA and is an attractive target for antiinfluenza drug discovery. ...

SHANKS GD, Burroughs SA, Sohn JD, Waters NC, et al. Enhanced risk of illness during the 1918 influenza pandemic after previous influenza-like illnesses in three military populations. Epidemiol Infect. 2016 Mar 9:1-6..  Abstract  
submitted by kickingbird at Mar, 14, 2016 from Epidemiol Infect. 2016 Mar 9:1-6. (via http://www.ncbi.nlm.nih.gov/pubmed/26957052)
The reasons for the unprecedented mortality during the 1918 influenza pandemic remain poorly understood. We examined morbidity records from three military cohorts from years prior to and during the 1918 ...

MARCHENKO VY, Susloparov IM, Kolosova NP, Goncharo. Highly pathogenic influenza H5N1 virus of clade 2.3.2.1c in Western Siberia. Arch Virol. 2016 Mar 3..  Abstract  
submitted by kickingbird at Mar, 14, 2016 from Arch Virol. 2016 Mar 3. (via http://www.ncbi.nlm.nih.gov/pubmed/26935914)
In the spring of 2015, avian influenza virus surveillance in Western Siberia resulted in isolation of several influenza H5N1 virus strains. The strains were isolated from several wild bird species. Investigation ...

GE F, Li X, Ju H, Yang D, et al. Genotypic evolution and antigenicity of H9N2 influenza viruses in Shanghai, China. Arch Virol. 2016 Mar 3.  Abstract  
submitted by kickingbird at Mar, 14, 2016 from Arch Virol. 2016 Mar 3 (via http://www.ncbi.nlm.nih.gov/pubmed/26935915)
H9N2 influenza viruses have been circulating in China since 1994, but a systematic investigation of H9N2 in Shanghai has not previously been undertaken. Here, using 14 viruses we isolated from poultry ...

BELSER JA, Creager HM, Sun X, Gustin KM, et al. Mammalian pathogenesis and transmission of H7N9 influenza viruses from three waves, 2013-2015. J Virol. 2016 Feb 24. pii: JVI.00134-16.  Abstract  
submitted by kickingbird at Mar, 7, 2016 from J Virol. 2016 Feb 24. pii: JVI.00134-16 (via http://www.ncbi.nlm.nih.gov/pubmed/26912620)
Three waves of human infection with H7N9 influenza viruses have concluded to date, but only viruses within the first wave (isolated between March-September 2013) have been extensively studied in mammalian ...

NAGESH PT, Husain M. Influenza A virus dysregulates host histone deacetylase 1 that inhibits viral infection in lung epithelial cells. J Virol. 2016 Feb 24. pii: JVI.00126-16.  Abstract  
submitted by kickingbird at Mar, 7, 2016 from J Virol. 2016 Feb 24. pii: JVI.00126-16 (via http://www.ncbi.nlm.nih.gov/pubmed/26912629)
Viruses dysregulate the host factors that inhibit virus infection. Here, we demonstrate that human enzyme, histone deacetylase 1 (HDAC1) is a new class of host factor that inhibits influenza A virus (IAV) ...

OBOHO I, Reed C, Gargiullo P, Leon M, et al. Benefit of Early Initiation of Influenza Antiviral Treatment to Pregnant Women Hospitalized With Laboratory-Confirmed Influenza. J Infect Dis. 2016 Feb 3. pii: jiw033.  Abstract  
submitted by kickingbird at Mar, 7, 2016 from J Infect Dis. 2016 Feb 3. pii: jiw033 (via http://www.ncbi.nlm.nih.gov/pubmed/26908745)
BACKGROUND: ?We describe the impact of early initiation of influenza antiviral treatment among pregnant women hospitalized with laboratory-confirmed influenza during the 2010-2014 influenza seasons. METHODS: ...

VIBOUD C, Simonsen L, Fuentes R, Flores J, et al. Global Mortality Impact of the 1957-1959 Influenza Pandemic. J Infect Dis. 2016 Mar 1;213(5):738-45. doi: 10.10.  Abstract  
submitted by kickingbird at Mar, 7, 2016 from J Infect Dis. 2016 Mar 1;213(5):738-45. doi: 10.10 (via http://www.ncbi.nlm.nih.gov/pubmed/26908781)
BACKGROUND: Quantitative estimates of the global burden of the 1957 influenza pandemic are lacking. Here we fill this gap by modeling historical mortality statistics. METHODS: We used annual rates ...

YU Yang, SI Weiying, YUAN Zhuangchuan, YAN Yan. Isolation and Identification of a Quail-origin H9N2 Subtype of the Influenza Virus and its Biologic Characterization. Chinese Journal of Virology, 2016(01).  Abstract  
submitted by kickingbird at Feb, 29, 2016 from Chinese Journal of Virology, 2016(01) (via http://www.cnki.net)
Abstract:A quail-origin subtype of the influenza virus was isolated from a human-infecting H7N9 subtype of the avian influenza virus found in a live poultry market and was given the name A/Quail/Hangzhou/1/2013 ...

SHA J, Chen X, Ren Y, Chen H, et al. Differences in the epidemiology and virology of mild, severe and fatal human infections with avian influenza A (H7N9) virus. Arch Virol. 2016 Feb 18..  Abstract  
submitted by kickingbird at Feb, 21, 2016 from Arch Virol. 2016 Feb 18. (via http://www.ncbi.nlm.nih.gov/pubmed/26887968)
A novel avian influenza A (H7N9) virus caused 5-10 % mild and 30.5 % fatal human infections as of December 10, 2015. In order to investigate the reason for the higher rate of fatal outcome of ...

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