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2024-4-18 14:54:38
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KIMBLE JB, Angel M, Wan H, Sutton TC, et al. Alternative reassortment events leading to transmissible H9N1 influenza viruses in the ferret model. J Virol. 2013 Oct 16..  Abstract  
submitted by kickingbird at Oct, 20, 2013 from J Virol. 2013 Oct 16. (via http://www.ncbi.nlm.nih.gov/pubmed/24131710)
Influenza A H9N2 viruses are common poultry pathogens that occasionally infect swine and humans. It has been shown previously with H9N2 viruses, reassortment can generate novel viruses with increased transmissibility. ...

SUN H, Sun Y, Pu J, Zhang Y, et al. Comparative virus replication and host innate response in human cells infected with 3 prevalent clades (2.3.4, 2.3.2 and 7) of highly pathogenic avian influenza H5N1 viruses. J Virol. 2013 Oct 16.  Abstract  
submitted by kickingbird at Oct, 20, 2013 from J Virol. 2013 Oct 16 (via http://www.ncbi.nlm.nih.gov/pubmed/24131718)
Highly pathogenic avian influenza H5N1 virus clades 2.3.4, 2.3.2 and 7 are the dominant co-circulating H5N1 viruses in poultry in China. However, humans appear to be clinically susceptible mostly to the ...

BARANOVICH T, Burnham AJ, Marathe BM, Armstrong J,. The Neuraminidase Inhibitor Oseltamivir is Effective against A/Anhui/1/2013 (H7N9) Influenza Virus in a Mouse Model of Acute Respiratory Distress Syndrome.. J Infect Dis. 2013 Oct 16.  Abstract  
submitted by kickingbird at Oct, 20, 2013 from J Infect Dis. 2013 Oct 16 (via http://www.ncbi.nlm.nih.gov/pubmed/24133191)
Background.?High mortality and uncertainty about the effectiveness of neuraminidase inhibitors (NAIs) in humans infected with A (H7N9) influenza viruses are public health concerns.Methods.?Susceptibility ...

WOODS CJ, Malaisree M, Long B, McIntosh-Smith S, e. Analysis and assay of oseltamivir-resistant mutants of influenza neuraminidase via direct observation of drug unbinding and rebinding in simulation. Biochemistry. 2013 Oct 15..  Abstract  
submitted by kickingbird at Oct, 20, 2013 from Biochemistry. 2013 Oct 15. (via http://www.ncbi.nlm.nih.gov/pubmed/24128064)
The emergence of influenza drug resistance is a major public health concern. The molecular basis of resistance to oseltamivir (Tamiflu) is investigated using a computational assay involving multiple 500 ...

SANT´ANNA FH, Borges LG, Fallavena PR, Gregi. Genomic analysis of pandemic and post-pandemic influenza A pH1N1 viruses isolated. Arch Virol. 2013 Oct 10..  Abstract  
submitted by kickingbird at Oct, 20, 2013 from Arch Virol. 2013 Oct 10. (via http://www.ncbi.nlm.nih.gov/pubmed/24114147)
During the 2009 influenza A pH1N1 pandemics in Brazil, the state that was most affected was Rio Grande do Sul (RS), with over 3,000 confirmed cases, including 298 deaths. While no cases were confirmed ...

JP Dudley, IM Mackay. Age-specific and sex-specific morbidity and mortality from avian influenza A(H7N9). Journal of Clinical Virology.  Abstract  
submitted by kickingbird at Oct, 20, 2013 from Journal of Clinical Virology (via http://www.journalofclinicalvirology.com/article/S1386-6532()
We used data on age and sex for 136 laboratory confirmed human A(H7N9) cases reported as of 11 August 2013 to compare age-specific and sex-specific patterns of morbidity and mortality from the avian influenza ...

SU WC, Chen YC, Tseng CH, Hsu PW, et al. Pooled RNAi screen identifies ubiquitin ligase Itch as crucial for influenza A virus release from the endosome during virus entry. Proc Natl Acad Sci U S A. 2013 Oct 7.  Abstract  
submitted by kickingbird at Oct, 13, 2013 from Proc Natl Acad Sci U S A. 2013 Oct 7 (via http://www.ncbi.nlm.nih.gov/pubmed/24101521)
Influenza viruses, like other viruses, rely on host factors to support their life cycle as viral proteins usually "hijack," or collaborate with, cellular proteins to execute their functions. Identification ...

WANG R, Xiao Y, Taubenberger JK. Rapid sequencing of influenza A virus vRNA, cRNA and mRNA non-coding regions. J Virol Methods. 2013 Oct 3. pii: S0166-0934(13)00.  Abstract  
submitted by kickingbird at Oct, 13, 2013 from J Virol Methods. 2013 Oct 3. pii: S0166-0934(13)00 (via http://www.ncbi.nlm.nih.gov/pubmed/24096269)
Characterizing the genomic sequences of influenza A viruses is important for pathophysiological and evolutionary studies. Noncoding regions (NCR) of influenza A virus have been shown to play critical roles ...

KALTHOFF D, Rohrs S, Hoper D, Hoffmann B, et al. Truncation and sequence shuffling of segment 6 generate replication-competent neuraminidase-negative influenza H5N1 viruses. J Virol. 2013 Oct 9..  Abstract  
submitted by kickingbird at Oct, 13, 2013 from J Virol. 2013 Oct 9. (via http://www.ncbi.nlm.nih.gov/pubmed/24109212)
Influenza viruses are highly genetically variable and escape from immunogenic pressure by antigenic changes in their surface proteins referred to as antigenic drift and antigenic shift. To assess the potential ...

JEGASKANDA S, Amarasena TH, Laurie KL, Tan HX, et. Standard trivalent influenza protein vaccination does not prime antibody-dependent cellular cytotoxicity (ADCC) in macaques. J Virol. 2013 Oct 9..  Abstract  
submitted by kickingbird at Oct, 13, 2013 from J Virol. 2013 Oct 9. (via http://www.ncbi.nlm.nih.gov/pubmed/24109221)
Yearly vaccination with the trivalent inactivated influenza vaccine (TIV) is recommended since current vaccines induce little cross neutralization to divergent influenza strains. Whether the TIV can induce ...

PERWITASARI O, Torrecilhas AC, Yan X, Johnson S, e. Targeting Cell Division Cycle 25 Homolog B (CDC25B) to Regulate Influenza Virus Replication. J Virol. 2013 Oct 9.  Abstract  
submitted by kickingbird at Oct, 13, 2013 from J Virol. 2013 Oct 9 (via http://www.ncbi.nlm.nih.gov/pubmed/24109234)
Influenza virus is a worldwide global health concern causing seasonal morbidity, mortality, and economic burden. Chemotherapeutics is available however rapid emergence of drug resistant influenza strains ...

SPENCER S, Gaglani M, Naleway A, Reynolds S, et al. Consistency of influenza A test results across respiratory specimen collection methods using real time reverse transcription polymerase chain reaction. J Clin Microbiol. 2013 Oct 9..  Abstract  
submitted by kickingbird at Oct, 13, 2013 from J Clin Microbiol. 2013 Oct 9. (via http://www.ncbi.nlm.nih.gov/pubmed/24108606)
In our prospective cohort study, we compared the performance of nasopharyngeal, oropharyngeal, and nasal swabs for the detection of influenza using real-time reverse transcription polymerase chain reaction ...

Chong KC, Fong HF, Zee CY.. Estimating the incidence reporting rates of new influenza pandemics at an early stage using travel data from the source country. Epidemiol Infect. 2013 Oct 10:1-9..  Abstract  
submitted by kickingbird at Oct, 13, 2013 from Epidemiol Infect. 2013 Oct 10:1-9. (via http://www.ncbi.nlm.nih.gov/pubmed/24107289)
SUMMARY During the surveillance of influenza pandemics, underreported data are a public health challenge that complicates the understanding of pandemic threats and can undermine mitigation efforts. We ...

Liao Q, Qian Z, Liu R, An L, Chen X.. Germacrone inhibits early stages of influenza virus infection. Antiviral Res. 2013 Oct 3. pii: S0166-3542.  Abstract  
submitted by kickingbird at Oct, 13, 2013 from Antiviral Res. 2013 Oct 3. pii: S0166-3542 (via http://www.ncbi.nlm.nih.gov/pubmed/24095670)
Highly pathogenic influenza viruses pose a serious public health threat to humans. Although vaccines are available, antivirals are needed to efficiently control disease progression and virus transmission ...

Tong S, Zhu X, Li Y, Shi M, Zhang J, et al. New World Bats Harbor Diverse Influenza A Viruses. PLoS Pathog 9(10): e1003657. doi:10.1371/journal..  Abstract  
submitted by kickingbird at Oct, 12, 2013 from PLoS Pathog 9(10): e1003657. doi:10.1371/journal. (via http://www.plospathogens.org/article/info%3Adoi%2F10.1371%2F)
Aquatic birds harbor diverse influenza A viruses and are a major viral reservoir in nature. The recent discovery of influenza viruses of a new H17N10 subtype in Central American fruit bats suggests that ...

YAMAMOTO N, Sakoda Y, Okamatsu M, Kida H, et al. Polymerase complex with lysine at position 627 of the PB2 of influenza virus A/Hong Kong/483/97 (H5N1) efficiently transcribes and replicates virus genes in mouse cells. Virus Res. 2013 Sep 23..  Abstract  
submitted by kickingbird at Oct, 6, 2013 from Virus Res. 2013 Sep 23. (via http://www.ncbi.nlm.nih.gov/pubmed/24070983)
Influenza virus A/Hong Kong/483/97 (H5N1) (HK483-K) has the PB2 with lysine at position 627 (PB2-627K) and is highly pathogenic in chickens and mice. On the other hand, the pathogenicity of mutant virus ...

NI F, Kondrashkina E, Wang Q. Structural basis for the divergent evolution of influenza B virus hemagglutinin. Virology. 2013 Nov.  Abstract  
submitted by kickingbird at Oct, 6, 2013 from Virology. 2013 Nov (via http://www.ncbi.nlm.nih.gov/pubmed/24074573)
Influenza A and B viruses are responsible for the severe morbidity and mortality worldwide in annual influenza epidemics. Currently circulating influenza B virus belongs to the B/Victoria or B/Yamagata ...

YE J, Xu Y, Harris J, Sun H, et al. Mutation from arginine to lysine at the position 189 of hemagglutinin contributes to the antigenic drift in H3N2 swine influenza viruses. Virology. 2013 Nov;.  Abstract  
submitted by kickingbird at Oct, 6, 2013 from Virology. 2013 Nov; (via http://www.ncbi.nlm.nih.gov/pubmed/24074585)
Two distinct antigenic clusters were previously identified among the H3N2 swine influenza A viruses (IAVs) and were designated H3N2SIV-alpha and H3N2SIV-beta (Feng et al., 2013. Journal of Virology 87 ...

LAKDAWALA SS, Shih AR, Jayaraman A, Lamirande EW,. Receptor specificity does not affect replication or virulence of the 2009 pandemic H1N1 influenza virus in mice and ferrets. Virology. 2013 Nov.  Abstract  
submitted by kickingbird at Oct, 6, 2013 from Virology. 2013 Nov (via http://www.ncbi.nlm.nih.gov/pubmed/24074599)
Human influenza viruses predominantly bind α2,6 linked sialic acid (SA) while avian viruses bind α2,3 SA-containing complex glycans. Virulence and tissue tropism of influenza viruses have been ascribed ...

SELADI-SCHULMAN J, Steel J, Lowen AC. Spherical influenza viruses have a fitness advantage in embryonated eggs, while filament-producing strains are selected in vivo. J Virol. 2013 Oct 2.  Abstract  
submitted by kickingbird at Oct, 6, 2013 from J Virol. 2013 Oct 2 (via http://www.ncbi.nlm.nih.gov/pubmed/24089563)
Influenza viruses can take on two distinct morphologies: filamentous or spherical. While the functional significance of each virion type is unclear, filaments are generally observed in low-passage isolates ...

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