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2024-11-22 8:42:14
Article

Xingdong Song, Jingman Tian, Minghui Li, Xiaoli Ba. Genetics and Pathogenicity of Influenza A (H4N6) Virus Isolated from Wild Birds in Jiangsu Province, China, 2023. Transboundary and Emerging Diseases, vol. 2024.  Abstract  
submitted by kickingbird at May, 30, 2024 from Transboundary and Emerging Diseases, vol. 2024 (via https://www.hindawi.com/journals/tbed/2024/7421277/)
During the routine surveillance, we isolated nine H4N6 subtype avian influenza viruses (AIVs) in Jiangsu Province, China, in March 2023. Phylogenetic analysis revealed that nine H4N6 viruses belonged to ...

Bing Liang, Menglu Fan, Qi Meng, Yaping Zhang, Jia. Effects of the Glycosylation of the HA Protein of H9N2 Subtype Avian Influenza Virus on the Pathogenicity in Mice and Antigenicity. Transboundary and Emerging Diseases, vol. 2024.  Abstract  
submitted by kickingbird at May, 30, 2024 from Transboundary and Emerging Diseases, vol. 2024 (via https://www.hindawi.com/journals/tbed/2024/6641285/)
As the H9N2 subtype avian influenza virus (H9N2 AIV) evolves naturally, mutations in the hemagglutinin (HA) protein still occur, which involves some sites with glycosylations. It is widely established ...

Qi An, Yuepeng Li, Zhuo Sun, Xiang Gao, Hongbin Wa. Spatial and Temporal Characteristic Analysis and Risk Assessment of Global Highly Pathogenic Avian Influenza H5N8 Subtype. Transboundary and Emerging Diseases, vol. 2024.  Abstract  
submitted by kickingbird at May, 30, 2024 from Transboundary and Emerging Diseases, vol. 2024 (via https://www.hindawi.com/journals/tbed/2024/5571668/)
H5N8 HPAI is a highly infectious avian disease that now poses a serious threat and potential risk to poultry farming, wild birds, and public health. In this study, to investigate the seasonality and transmission ...

Kamila Dziadek, Edyta ?wi?toń, Edyta Kozak, Krzysz. Phylogenetic and Molecular Characteristics of Wild Bird-Origin Avian Influenza Viruses Circulating in Poland in 2018-2022: Reassortment, Multiple Introductions, and Wild Bird–Poultry Epi Links. Transboundary and Emerging Diseases, vol. 2024.  Abstract  
submitted by kickingbird at May, 30, 2024 from Transboundary and Emerging Diseases, vol. 2024 (via https://www.hindawi.com/journals/tbed/2024/6661672/)
Since 2020, a significant increase in the severity of H5Nx highly pathogenic avian influenza (HPAI) epidemics in poultry and wild birds has been observed in Poland. To further investigate the genetic diversity ...

Cassandra L. Andrew, Shannon L. Russell, Michelle. Descriptive Epidemiology and Phylodynamics of the “First Wave” of an Outbreak of Highly Pathogenic Avian Influenza (H5N1 Clade 2.3.4.4b) in British Columbia and the Yukon, Canada, April to Sep 2022. Transboundary and Emerging Diseases, vol. 2024.  Abstract  
submitted by kickingbird at May, 30, 2024 from Transboundary and Emerging Diseases, vol. 2024 (via https://www.hindawi.com/journals/tbed/2024/2327939/)
Highly pathogenic avian influenza (HPAI) is a viral disease that causes significant rates of morbidity and mortality in domestic poultry and wild birds, with occasional spillover into mammals, including ...

Huiyan Yu, Ke Jin, Songning Ding, Ke Xu, Xian Qi,. Severe Avian Influenza A H5N1 Clade 2.3.4.4b Virus Infection in a Human with Continuation of SARS-CoV-2 Viral RNAs. Transboundary and Emerging Diseases, vol. 2024.  Abstract  
submitted by kickingbird at May, 30, 2024 from Transboundary and Emerging Diseases, vol. 2024 (via https://www.hindawi.com/journals/tbed/2024/8819622/)
Background. Since 2020, global attention has heightened towards epidemics caused by avian influenza A H5N1 virus of clade 2.3.4.4b in birds and mammals. This study presents the epidemiological history, ...

Kevin S Kuchinski, etc.,al. [preprint]Detection of a reassortant swine- and human-origin H3N2 influenza A virus in farmed mink in British Columbia, Canada. https://doi.org/10.1101/2024.05.27.596080.  Abstract  
submitted by kickingbird at May, 30, 2024 from https://doi.org/10.1101/2024.05.27.596080 (via https://www.biorxiv.org/content/10.1101/2024.05.27.596080v1)
In December 2021, influenza A viruses (IAV) were detected in a population of farmed mink in British Columbia, Canada. Based on genomic sequencing and phylogenetic analysis, these IAVs were subtyped as ...

Vigeveno RM, Han AX, de Vries RP, Parker E, de Haa. Long-term evolution of human seasonal influenza virus A(H3N2) is associated with an increase in polymerase complex activity. Virus Evol. 2024 May 4;10(1):veae030.  Abstract  
submitted by kickingbird at May, 29, 2024 from Virus Evol. 2024 May 4;10(1):veae030 (via https://academic.oup.com/ve/article/10/1/veae030/7665189)
Since the influenza pandemic in 1968, influenza A(H3N2) viruses have become endemic. In this state, H3N2 viruses continuously evolve to overcome immune pressure as a result of prior infection or vaccination, ...

Catani JPP, Smet A, Ysenbaert T, Vuylsteke M, Bott. The antigenic landscape of human influenza N2 neuraminidases from 2009 until 2017. Elife. 2024 May 28;12:RP90782.  Abstract  
submitted by kickingbird at May, 29, 2024 from Elife. 2024 May 28;12:RP90782 (via https://elifesciences.org/articles/90782)
Human H3N2 influenza viruses are subject to rapid antigenic evolution which translates into frequent updates of the composition of seasonal influenza vaccines. Despite these updates, the effectiveness ...

ia M, Zhao H, Morano NC, Lu H, Lui YM, Du H, Becke. Human neutralizing antibodies target a conserved lateral patch on H7N9 hemagglutinin head. Nat Commun. 2024 May 27;15(1):4505.  Abstract  
submitted by kickingbird at May, 29, 2024 from Nat Commun. 2024 May 27;15(1):4505 (via https://www.nature.com/articles/s41467-024-48758-4)
Avian influenza A virus H7N9 causes severe human infections with >30% fatality. Currently, there is no H7N9-specific prevention or treatment for humans. Here, from a 2013 H7N9 convalescent case in Hong ...

Kessler S, Burke B, Andrieux G, Schink?the J, Hamb. Deciphering bat influenza H18N11 infection dynamics in male Jamaican fruit bats on a single-cell level. Nat Commun. 2024 May 27;15(1):4500.  Abstract  
submitted by kickingbird at May, 29, 2024 from Nat Commun. 2024 May 27;15(1):4500 (via https://www.nature.com/articles/s41467-024-48934-6)
Jamaican fruit bats (Artibeus jamaicensis) naturally harbor a wide range of viruses of human relevance. These infections are typically mild in bats, suggesting unique features of their immune system. To ...

Swanson NJ, Girish J, Yunker M, Liu H, Norton J, H. [preprint]Clade-defining mutations in human H1N1 hemagglutinin protein from 2021-2023 have opposing effects on in vitro fitness and antigenic drift. https://doi.org/10.1101/2024.05.18.594815.  Abstract  
submitted by kickingbird at May, 29, 2024 from https://doi.org/10.1101/2024.05.18.594815 (via https://www.biorxiv.org/content/10.1101/2024.05.18.594815v1)
Seasonal influenza viruses frequently acquire mutations that have the potential to alter both virus replication and antigenic profile. Recent seasonal H1N1 viruses have acquired mutations to their hemagglutinin ...

Teo QW, Wang Y, Lv H, Mao KJ, Tan TJC, Huan YW, Ri. [preprint]Deep mutational scanning of influenza A virus NEP reveals pleiotropic mutations in its N-terminal domain. https://doi.org/10.1101/2024.05.16.594574.  Abstract  
submitted by kickingbird at May, 29, 2024 from https://doi.org/10.1101/2024.05.16.594574 (via https://www.biorxiv.org/content/10.1101/2024.05.16.594574v1)
The influenza A virus nuclear export protein (NEP) is a multifunctional protein that is essential for the viral life cycle and has very high sequence conservation. However, since the open reading frame ...

Guiomar R, Pereira da Silva S, Costa I, Conde P, C. Seroprevalence of Protective Antibodies Against Influenza and the Reduction of the Influenza Incidence Rate: An Annual Repeated Cross-Sectional Study From 2014 to 2019. Influenza Other Respir Viruses. 2024 May;18(5):e13.  Abstract  
submitted by kickingbird at May, 29, 2024 from Influenza Other Respir Viruses. 2024 May;18(5):e13 (via https://onlinelibrary.wiley.com/doi/10.1111/irv.13307)
Background: Seroepidemiological studies provide estimates of population-level immunity, prevalence/incidence of infections, and evaluation of vaccination programs. We assessed the seroprevalence of protective ...

Brogaard L, Heegaard PMH, Larsen LE, Skovgaard K. Pulmonary MicroRNA expression after heterologous challenge with swine influenza A virus (H1N2) in immunized and non-immunized pigs. Virology. 2024 May 23;596:110117.  Abstract  
submitted by kickingbird at May, 29, 2024 from Virology. 2024 May 23;596:110117 (via https://www.sciencedirect.com/science/article/abs/pii/S00426)
MicroRNAs (miRNAs) contribute to post-transcriptional modulation of the host response during influenza A virus (IAV) infection and may be involved in shaping disease severity. Differential disease severity ...

Nieves Sevilla, Wendy Lizarraga, Victor Jimenez-Va. Highly pathogenic avian influenza A (H5N1) virus outbreak in Peru in 2022~2023. Infectious Medicine, 2024.  Abstract  
submitted by kickingbird at May, 27, 2024 from Infectious Medicine, 2024 (via https://www.sciencedirect.com/science/article/pii/S2772431X2)
BackgroundAn epizootic of highly pathogenic avian influenza A (H5N1) has spread worldwide since 2022. Even though this virus has been extensively studied for many decades, little is known about its evolution ...

Yanyi Huang, Peiyang Zhang, Shuyi Han, Bin Hu, Qin. Effect of Enteromorpha polysaccharides on gut-lung axis in mice infected with H5N1 influenza virus. Virology, Volume 593, 2024.  Abstract  
submitted by kickingbird at May, 27, 2024 from Virology, Volume 593, 2024 (via https://www.sciencedirect.com/science/article/pii/S004268222)
Enteromorpha polysaccharides (EPPs) have been reported to have antiviral and anti-inflammatory properties. To explore the effect of EPPs on H5N1-infected mice, mice were pretreated with EPPs before being ...

Gonzalez-Obando J, Zuluaga-Cabrera A, Moreno I, ús. First Molecular Detection and Epidemiological Analysis of Equine Influenza Virus in Two Regions of Colombia, 2020~2023. Viruses. 2024; 16(6):839.  Abstract  
submitted by kickingbird at May, 27, 2024 from Viruses. 2024; 16(6):839 (via https://www.mdpi.com/1999-4915/16/6/839)
Equine influenza is a viral disease caused by the equine influenza virus (EIV), and according to the WOAH, it is mandatory to report these infections. In Latin America and Colombia, EIV risk factors have ...

Bernadeta Dadonaite, etc.,al. [preprint]Deep mutational scanning of H5 hemagglutinin to inform influenza virus surveillance. https://doi.org/10.1101/2024.05.23.595634.  Abstract  
submitted by kickingbird at May, 26, 2024 from https://doi.org/10.1101/2024.05.23.595634 (via https://www.biorxiv.org/content/10.1101/2024.05.23.595634v1)
H5 influenza is considered a potential pandemic threat. Recently, H5 viruses belonging to clade 2.3.4.4b have caused large outbreaks in avian and multiple non-human mammalian species. Previous studies ...

Valerie Le Sage, etc.,al. [preprint]Influenza H5N1 and H1N1 viruses remain infectious in unpasteurized milk on milking machinery surfaces. https://doi.org/10.1101/2024.05.22.24307745.  Abstract  
submitted by kickingbird at May, 25, 2024 from https://doi.org/10.1101/2024.05.22.24307745 (via https://www.medrxiv.org/content/10.1101/2024.05.22.24307745v)
Spillover of highly pathogenic avian H5N1 into the cattle population poses a risk to humans through the close contact with farm workers. High viral loads of influenza viruses in the unpasteurized milk ...

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