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2024-4-19 11:23:13
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Yang H, Dong Y, Bian Y, Huo C, Zhu C, Qin T, Chen. The synergistic effect of residues 32T and 550L in the PA protein of H5 subtype avian influenza virus contributes to viral pathogenicity in mice. PLoS Pathog. 2023 Jul 3;19(7):e1011489.  Abstract  
submitted by kickingbird at Jul, 4, 2023 from PLoS Pathog. 2023 Jul 3;19(7):e1011489 (via https://journals.plos.org/plospathogens/article?id=10.1371/j)
The avian influenza virus (AIV) PA protein contributes to viral replication and pathogenicity; however, its interaction with innate immunity is not well understood. Here, we report that the H5 subtype ...

Park J, Song CS, Chung DH, Choi S, Kwon J, Youk S,. Chimeric H5 influenza virus-like particle vaccine elicits broader cross-clade antibody responses in chickens than in ducks. Front Vet Sci. 2023 Jun 15;10:1158233.  Abstract  
submitted by kickingbird at Jul, 4, 2023 from Front Vet Sci. 2023 Jun 15;10:1158233 (via https://www.frontiersin.org/articles/10.3389/fvets.2023.1158)
Eurasian-lineage highly pathogenic avian influenza (HPAI) H5 viruses have spread throughout Asia, the Middle East, Europe, Africa, and most recently, North and South America. These viruses are independently ...

Yin Y, Qiu Z, Lei Y, Huang J, Sun Y, Liu H, Wu W,. Screening and identification of specific cluster miRNAs in N2a cells infected by H7N9 virus. Virus Genes. 2023 Jul 3.  Abstract  
submitted by kickingbird at Jul, 4, 2023 from Virus Genes. 2023 Jul 3 (via https://link.springer.com/article/10.1007/s11262-023-01996-y)
This study aims to screen and identify specific cluster miRNAs of H7N9 virus-infected N2a cells and explore the possible pathogenesis of these miRNAs. The N2a cells are infected with H7N9 and H1N1 influenza ...

Li Y, Liu P, Hao T, Liu S, Wang X, Xie Y, Xu K, Le. Rational design of an influenza-COVID-19 chimeric protective vaccine with S-RBD and HA-stalk. Emerg Microbes Infect. 2023 Jul 3:2231573.  Abstract  
submitted by kickingbird at Jul, 4, 2023 from Emerg Microbes Infect. 2023 Jul 3:2231573 (via https://www.tandfonline.com/doi/full/10.1080/22221751.2023.2)
Highly contagious respiratory illnesses like influenza and COVID-19 pose serious risks to public health. A two-in-one vaccine would be ideal to avoid multiple vaccinations for these diseases. Here, we ...

McMahon A, Andrews R, Groves D, Ghani SV, Cordes T. High-throughput super-resolution analysis of influenza virus pleomorphism reveals insights into viral spatial organization. PLoS Pathog. 2023 Jun 30;19(6):e1011484.  Abstract  
submitted by kickingbird at Jul, 1, 2023 from PLoS Pathog. 2023 Jun 30;19(6):e1011484 (via https://journals.plos.org/plospathogens/article?id=10.1371/j)
Many viruses form highly pleomorphic particles. In influenza, virion structure is of interest not only in the context of virus assembly, but also because pleomorphic variations may correlate with infectivity ...

Pinto RM, Bakshi S, Lytras S, Zakaria MK, Swingler. BTN3A3 evasion promotes the zoonotic potential of influenza A viruses. Nature. 2023 Jun 28.  Abstract  
submitted by kickingbird at Jun, 30, 2023 from Nature. 2023 Jun 28 (via https://www.nature.com/articles/s41586-023-06261-8)
Spillover events of avian influenza A viruses (IAVs) to humans could represent the first step in a future pandemic1. Several factors that limit the transmission and replication of avian IAVs in mammals ...

Kim JY, Lee SH, Kim DW, Lee DW, Song CS, Lee DH, K. Detection of intercontinental reassortant H6 avian influenza viruses from wild birds in South Korea, 2015 and 2017. Front Vet Sci. 2023 Jun 12;10:1157984.  Abstract  
submitted by kickingbird at Jun, 30, 2023 from Front Vet Sci. 2023 Jun 12;10:1157984 (via https://www.frontiersin.org/articles/10.3389/fvets.2023.1157)
Avian influenza viruses (AIVs) in wild birds are phylogenetically separated in Eurasian and North American lineages due to the separated distribution and migration of wild birds. However, AIVs are occasionally ...

Cha RM, Lee YN, Park MJ, Baek YG, Shin JI, Jung CH. Genetic Characterization and Pathogenesis of H5N1 High Pathogenicity Avian Influenza Virus Isolated in South Korea during 2021-2022. Viruses. 2023 Jun 20;15(6):1403.  Abstract  
submitted by kickingbird at Jun, 30, 2023 from Viruses. 2023 Jun 20;15(6):1403 (via https://www.mdpi.com/1999-4915/15/6/1403)
High pathogenicity avian influenza (HPAI) viruses of clade 2.3.4.4 H5Nx have been circulating in poultry and wild birds worldwide since 2014. In South Korea, after the first clade 2.3.4.4b H5N1 HPAI viruses ...

Meseko C, Milani A, Inuwa B, Chinyere C, Shittu I,. The Evolution of Highly Pathogenic Avian Influenza A (H5) in Poultry in Nigeria, 2021-2022. Viruses. 2023 Jun 17;15(6):1387.  Abstract  
submitted by kickingbird at Jun, 30, 2023 from Viruses. 2023 Jun 17;15(6):1387 (via https://www.mdpi.com/1999-4915/15/6/1387)
In 2021, amidst the COVID-19 pandemic and global food insecurity, the Nigerian poultry sector was exposed to the highly pathogenic avian influenza (HPAI) virus and its economic challenges. Between 2021 ...

Abolnik C, Phiri T, Peyrot B, de Beer R, Snyman A,. The Molecular Epidemiology of Clade 2.3.4.4B H5N1 High Pathogenicity Avian Influenza in Southern Africa, 2021-2022. Viruses. 2023 Jun 16;15(6):1383.  Abstract  
submitted by kickingbird at Jun, 30, 2023 from Viruses. 2023 Jun 16;15(6):1383 (via https://www.mdpi.com/1999-4915/15/6/1383)
In southern Africa, clade 2.3.4.4B H5N1 high pathogenicity avian influenza (HPAI) was first detected in South African (SA) poultry in April 2021, followed by outbreaks in poultry or wild birds in Lesotho ...

Slomka MJ, Reid SM, Byrne AMP, Coward VJ, Seekings. Efficient and Informative Laboratory Testing for Rapid Confirmation of H5N1 (Clade 2.3.4.4) High-Pathogenicity Avian Influenza Outbreaks in the United Kingdom. Viruses. 2023 Jun 9;15(6):1344.  Abstract  
submitted by kickingbird at Jun, 30, 2023 from Viruses. 2023 Jun 9;15(6):1344 (via https://www.mdpi.com/1999-4915/15/6/1344)
During the early stages of the UK 2021-2022 H5N1 high-pathogenicity avian influenza virus (HPAIV) epizootic in commercial poultry, 12 infected premises (IPs) were confirmed by four real-time reverse-transcription-polymerase ...

Niu J, Meng G. Roles and Mechanisms of NLRP3 in Influenza Viral Infection. Viruses. 2023 Jun 8;15(6):1339.  Abstract  
submitted by kickingbird at Jun, 30, 2023 from Viruses. 2023 Jun 8;15(6):1339 (via https://www.mdpi.com/1999-4915/15/6/1339)
Pathogenic viral infection represents a major challenge to human health. Due to the vast mucosal surface of respiratory tract exposed to the environment, host defense against influenza viruses has perpetually ...

Lv X, Tian J, Li X, Bai X, Li Y, Li M, An Q, Song. H10Nx avian influenza viruses detected in wild birds in China pose potential threat to mammals. One Health. 2023 Feb 21;16:100515.  Abstract  
submitted by kickingbird at Jun, 27, 2023 from One Health. 2023 Feb 21;16:100515 (via https://www.sciencedirect.com/science/article/pii/S235277142)
H10 subtype avian influenza viruses (AIVs) have been isolated from wild and domestic avian species worldwide and have occasionally crossed the species barrier to mammalian hosts. Fatal human cases of H10N8 ...

Swanson NJ, Marinho P, Dziedzic A, Jedlicka A, Liu. 2019-2020 H1N1 clade A5a.1 viruses have better in vitro fitness compared with the co-circulating A5a.2 clade. Sci Rep. 2023 Jun 23;13(1):10223.  Abstract  
submitted by kickingbird at Jun, 25, 2023 from Sci Rep. 2023 Jun 23;13(1):10223 (via https://www.nature.com/articles/s41598-023-37122-z)
Surveillance for emerging human influenza virus clades is important for identifying changes in viral fitness and assessing antigenic similarity to vaccine strains. While fitness and antigenic structure ...

Okuya K, Khalil AM, Esaki M, Nishi N, Koyamada D,. Newly emerged genotypes of highly pathogenic H5N8 avian influenza viruses in Kagoshima prefecture, Japan during winter 2020/21. J Gen Virol. 2023 Jun;104(6).  Abstract  
submitted by kickingbird at Jun, 25, 2023 from J Gen Virol. 2023 Jun;104(6) (via https://pubmed.ncbi.nlm.nih.gov/37351928/)
During the 2020/21 winter season, 29 and 10 H5N8 high pathogenicity avian influenza viruses (HPAIVs) were isolated from environmental water and wild birds, respectively, in Kagoshima prefecture, Japan. ...

Cheung J, Bui AN, Younas S, Edwards KM, Nguyen HQ,. Long-Term Epidemiology and Evolution of Swine Influenza Viruses, Vietnam. Emerg Infect Dis. 2023 Jul;29(7):1397-1406.  Abstract  
submitted by kickingbird at Jun, 25, 2023 from Emerg Infect Dis. 2023 Jul;29(7):1397-1406 (via https://wwwnc.cdc.gov/eid/article/29/7/23-0165_article)
Influenza A viruses are a One Health threat because they can spill over between host populations, including among humans, swine, and birds. Surveillance of swine influenza virus in Hanoi, Vietnam, during ...

Tian J, Bai X, Li M, Zeng X, Xu J, Li P, Wang M, S. Highly Pathogenic Avian Influenza Virus (H5N1) Clade 2.3.4.4b Introduced by Wild Birds, China, 2021. Emerg Infect Dis. 2023 Jul;29(7):1367-1375.  Abstract  
submitted by kickingbird at Jun, 23, 2023 from Emerg Infect Dis. 2023 Jul;29(7):1367-1375 (via https://wwwnc.cdc.gov/eid/article/29/7/22-1149_article)
Highly pathogenic avian influenza (HPAI) subtype H5N1 clade 2.3.4.4b virus has spread globally, causing unprecedented large-scale avian influenza outbreaks since 2020. In 2021, we isolated 17 highly pathogenic ...

Graaf A, Piesche R, Sehl-Ewert J, Grund C, Pohlman. Low Susceptibility of Pigs against Experimental Infection with HPAI Virus H5N1 Clade 2.3.4.4b. Emerg Infect Dis. 2023 Jul;29(7):1492-1495.  Abstract  
submitted by kickingbird at Jun, 23, 2023 from Emerg Infect Dis. 2023 Jul;29(7):1492-1495 (via https://wwwnc.cdc.gov/eid/article/29/7/23-0296_article)
We found that nasal and alimentary experimental exposure of pigs to highly pathogenic avian influenza virus H5N1 clade 2.3.4.4b was associated with marginal viral replication, without inducing any clinical ...

Liang Y. Pathogenicity and virulence of influenza. Virulence. 2023 Dec;14(1):2223057.  Abstract  
submitted by kickingbird at Jun, 21, 2023 from Virulence. 2023 Dec;14(1):2223057 (via https://www.tandfonline.com/doi/full/10.1080/21505594.2023.2)
Influenza viruses, including four major types (A, B, C, and D), can cause mild-to-severe and lethal diseases in humans and animals. Influenza viruses evolve rapidly through antigenic drift (mutation) and ...

Rafique S, Rashid F, Mushtaq S, Ali A, Li M, Luo S. Global review of the H5N8 avian influenza virus subtype. Front Microbiol. 2023 Jun 2;14:1200681.  Abstract  
submitted by kickingbird at Jun, 20, 2023 from Front Microbiol. 2023 Jun 2;14:1200681 (via https://www.frontiersin.org/articles/10.3389/fmicb.2023.1200)
Orthomyxoviruses are negative-sense, RNA viruses with segmented genomes that are highly unstable due to reassortment. The highly pathogenic avian influenza (HPAI) subtype H5N8 emerged in wild birds in ...

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