Hibino A，etc.,al. Neuraminidase inhibitor susceptibility and evolutionary analysis of human influenza B isolates from three Asian countries during 2012~2015. Infect Genet Evol. 2018 Apr 14;62:27-33. Abstract
submitted by kickingbird at Apr, 24, 2018 from Infect Genet Evol. 2018 Apr 14;62:27-33 (via https://www.ncbi.nlm.nih.gov/pubmed/29665435)
Influenza B viruses of both the Yamagata and the Victoria lineages are implicated in a large proportion of the morbidity and mortality associated with influenza outbreaks. In this study, we characterized ... Renu S, etc.,al. Intranasal delivery of influenza antigen by nanoparticles, but not NKT-cell adjuvant differentially induces the expression of B-cell activation factors in mice and swine. Cell Immunol. 2018 Apr 11.. Abstract
submitted by kickingbird at Apr, 24, 2018 from Cell Immunol. 2018 Apr 11. (via https://www.sciencedirect.com/science/article/abs/pii/S00088)
Intranasal vaccination of pigs with poly lactic-co-glycolic acid and polyanhydride nanoparticles delivered inactivated influenza virus provides cross-reactive T-cell response, but not antibody response, ... Reber AJ, Music N, Kim JH, Gansebom S, Chen J. Extensive T cell cross-reactivity between diverse seasonal influenza strains in the ferret model. Sci Rep. 2018 Apr 17;8(1):6112.. Abstract
submitted by kickingbird at Apr, 24, 2018 from Sci Rep. 2018 Apr 17;8(1):6112. (via http://www.nature.com/articles/s41598-018-24394-z)
Influenza virus causes widespread, yearly epidemics by accumulating surface protein mutations to escape neutralizing antibodies established from prior exposure. In contrast to antibody epitopes, T cell ... Lin X, Yu S, Guo K, Sun X, Yi H, Jin M. Reassortant H5N1 Avian Influenza Virus Bearing PB2 Gene From a 2009 Pandemic H1N1 Exhibits Increased Pathogenicity in Mice. Front. Microbiol., 03 April 2018. Abstract
submitted by kickingbird at Apr, 24, 2018 from Front. Microbiol., 03 April 2018 (via https://www.frontiersin.org/articles/10.3389/fmicb.2018.0063)
Reassortment is a key driving force of the evolution and host adaptation of the influenza virus. A(H1N1)pdm2009 (pdm09), a novel H1N1 influenza viral subtype, caused a pandemic in 2009. The strain was ... Judith M. A. van den Brand, etc.,al. Wild ducks excrete highly pathogenic avian influenza virus H5N8 (2014~2015) without clinical or pathological evidence of disease. Emerging Microbes & Infections volume 7, Article. Abstract
submitted by kickingbird at Apr, 21, 2018 from Emerging Microbes & Infections volume 7, Article (via https://www.nature.com/articles/s41426-018-0070-9)
Highly pathogenic avian influenza (HPAI) is essentially a poultry disease. Wild birds have traditionally not been involved in its spread, but the epidemiology of HPAI has changed in recent years. After ... Ferhadian D, etc.,al. Structural and Functional Motifs in Influenza Virus RNAs. Front Microbiol. 2018 Mar 29;9:559. Abstract
submitted by kickingbird at Apr, 21, 2018 from Front Microbiol. 2018 Mar 29;9:559 (via https://www.ncbi.nlm.nih.gov/pubmed/29651275)
Influenza A viruses (IAV) are responsible for recurrent influenza epidemics and occasional devastating pandemics in humans and animals. They belong to the Orthomyxoviridae family and their genome consists ... Meseko C, etc.,al. Evidence of exposure of domestic pigs to Highly Pathogenic Avian Influenza H5N1 in Nigeria. Sci Rep. 2018 Apr 12;8(1):590. Abstract
submitted by kickingbird at Apr, 21, 2018 from Sci Rep. 2018 Apr 12;8(1):590 (via https://www.ncbi.nlm.nih.gov/pubmed/29651056)
Avian influenza viruses (AIV) potentially transmit to swine as shown by experiments, where further reassortment may contribute to the generation of pandemic strains. Associated risks of AIV inter-species ... Liu H, Xiong C, Chen J, Chen G, Zhang J, Li Y. Two genetically diverse H7N7 avian influenza viruses isolated from migratory birds in central China. Emerg Microbes Infect. 2018 Apr 11. Abstract
submitted by kickingbird at Apr, 17, 2018 from Emerg Microbes Infect. 2018 Apr 11 (via https://www.ncbi.nlm.nih.gov/pubmed/29636458)
After the emergence of H7N9 avian influenza viruses (AIV) in early 2013 in China, active surveillance of AIVs in migratory birds was undertaken, and two H7N7 strains were subsequently recovered from the ... Slater T, Eckerle I, Chang KC. Bat lung epithelial cells show greater host species-specific innate resistance than MDCK cells to human and avian influenza viruses. Virol J. 2018 Apr 10. Abstract
submitted by kickingbird at Apr, 17, 2018 from Virol J. 2018 Apr 10 (via https://www.ncbi.nlm.nih.gov/pubmed/29636078)
BACKGROUND: With the recent discovery of novel H17N10 and H18N11 influenza viral RNA in bats and report on high frequency of avian H9 seroconversion in a species of free ranging bats, an important issue ... Wang C, Zhang Y, etc.,al. The use of pyrosequencing for detection of hemagglutinin mutations associated with increased pathogenicity of H5N1 avian influenza viruses in mammals. J Vet Diagn Invest. 2018 Apr 1. Abstract
submitted by kickingbird at Apr, 17, 2018 from J Vet Diagn Invest. 2018 Apr 1 (via https://www.ncbi.nlm.nih.gov/pubmed/29633913)
Hemagglutinin (HA) cleavage is critical for virulence of influenza viruses. The amino acid residue at the P6 position of the HA cleavage site (HACS) has been shown to be most variable and to have a direct ... Liu Y, Chia ZH, Liew JNMH, Or SM, Phua KKL.. Modulation of mRNA Translation and Cell Viability by Influenza A Virus Derived Nonstructural Protein 1. Nucleic Acid Ther. 2018 Apr 10.. Abstract
submitted by kickingbird at Apr, 17, 2018 from Nucleic Acid Ther. 2018 Apr 10. (via https://www.liebertpub.com/doi/10.1089/nat.2017.0712)
Translation of in vitro transcribed messenger RNA (mRNA) is known to be compromised by cell's innate immune responses. Herein we show that when mRNA encoding nonstructural protein 1 (NS1), an immune evasion ... T Vesikari, etc.,al. Efficacy, immunogenicity, and safety evaluation of an MF59-adjuvanted quadrivalent influenza virus vaccine compared with non-adjuvanted influenza vaccine in children: a multicentre, randomised control. Lancet Respir Med. Abstract
submitted by kickingbird at Apr, 17, 2018 from Lancet Respir Med (via www.thelancet.com/journals/lanres/article/PIIS2213-2600%2818)
ackgroundYoung children have immature immune systems and respond poorly to standard influenza vaccines. The oil-in-water emulsion adjuvant MF59 can increase antigen uptake, macrophage recruitment, lymph ... Lapuente D, Ruzsics Z, Thirion C, Tenbusch M, et a. Evaluation of adenovirus 19a as a novel vector for mucosal vaccination against influenza A viruses. Lapuente D, Ruzsics Z, Thirion C, Tenbusch M, et a. Abstract
submitted by kickingbird at Apr, 16, 2018 from Lapuente D, Ruzsics Z, Thirion C, Tenbusch M, et a (via https://www.ncbi.nlm.nih.gov/m/pubmed/29628150/)
Since preexisting immunity and enhanced infection rates in a clinical trial of an HIV vaccine have raised some concerns on adenovirus (Ad) serotype 5-based vaccines, we evaluated the subgroup D adenovirus ... Bae JY, Lee I, Kim JI, Park S, et al. A Single Amino Acid at the Polymerase Acidic Protein Determines the Pathogenicity of Influenza B Viruses. J Virol 2018 Apr 11. Abstract
submitted by kickingbird at Apr, 16, 2018 from J Virol 2018 Apr 11 (via https://www.ncbi.nlm.nih.gov/m/pubmed/29643248/)
Influenza B virus (IBV) is one of the human respiratory viruses and the targets of seasonal vaccination. However, the bifurcation of two antigenically distinct lineages of IBVs makes it difficult to arrange ... Wang Y, Guo Q, Yan Z, Zhou D, et al. Factors Associated With Prolonged Viral Shedding in Patients With Avian Influenza A(H7N9) Virus Infection. J Infect Dis 2018 Apr 10. Abstract
submitted by kickingbird at Apr, 16, 2018 from J Infect Dis 2018 Apr 10 (via https://www.ncbi.nlm.nih.gov/m/pubmed/29648602/)
Background: Data are limited on the impact of neuraminidase inhibitor (NAI) treatment on avian influenza A(H7N9) virus RNA shedding. Methods: In this multicenter, retrospective study, data were collected ... Zhu H, Lee ACY, Li C, Mak WWN, Chen YY, etc.,al. Low population serum microneutralization antibody titer against the predominating influenza A(H3N2) N121K virus during the severe influenza summer peak of Hong Kong in 2017. Emerg Microbes Infect. 2018 Mar 6;7(1):23. Abstract
submitted by kickingbird at Apr, 9, 2018 from Emerg Microbes Infect. 2018 Mar 6;7(1):23 (via https://www.ncbi.nlm.nih.gov/pubmed/29511175)
The 2017 Hong Kong influenza A(H3N2) summer season was unexpectedly severe. However, antigenic characterization of the 2017 circulating A(H3N2) viruses using ferret antisera did not show significant antigenic ... Liping Ma, etc.,al. Two reassortant types of highly pathogenic H5N8 avian influenza virus from wild birds in Central China in 2016. Emerging Microbes & Infections (2018) 7:14. Abstract
submitted by kickingbird at Apr, 9, 2018 from Emerging Microbes & Infections (2018) 7:14 (via https://www.ncbi.nlm.nih.gov/pubmed/29410395)
Since 2016, the highly pathogenic avian influenza H5N8 virus has emerged in the Central Asian flyway and Europe, causing massive deaths in poultry and wild birds. In this study, we isolated and identified ... Reeves AB, Hall JS, Poulson RL, etc.,al. Influenza A virus recovery, diversity, and intercontinental exchange: A multi-year assessment of wild bird sampling at Izembek National Wildlife Refuge, Alaska. PLoS One. 2018 Apr 5;13(4):e0195327. Abstract
submitted by kickingbird at Apr, 8, 2018 from PLoS One. 2018 Apr 5;13(4):e0195327 (via https://www.ncbi.nlm.nih.gov/pubmed/29621333)
Western Alaska is a potential point-of-entry for foreign-origin influenza A viruses (IAVs) into North America via migratory birds. We sampled waterfowl and gulls for IAVs at Izembek National Wildlife Refuge ... Wu XX, Deng XL, Yu DS, etc.,al. The Protective Effects of the A/ZJU01/ PR8/2013 Split H7N9 Avian Influenza Vaccine Against Highly Pathogenic H7N9 in BALB/c Mice. Cell Physiol Biochem. 2018 Mar 28. Abstract
submitted by kickingbird at Apr, 8, 2018 from Cell Physiol Biochem. 2018 Mar 28 (via https://www.ncbi.nlm.nih.gov/pubmed/29617693)
BACKGROUND/AIMS: Since the first case of novel H7N9 infection was reported, China has experienced five epidemics of H7N9. During the fifth wave, a highly pathogenic H7N9 strain emerged. In order to assess ... Gao R, Gu M, Liu K, Li Q, Li J, Shi L, etc.,al. T160A mutation-induced deglycosylation at site 158 in hemagglutinin is a critical determinant of the dual receptor binding properties of clade 2.3.4.4 H5NX subtype avian influenza viruses. Vet Microbiol. 2018 Apr;217:158-166. Abstract
submitted by kickingbird at Apr, 8, 2018 from Vet Microbiol. 2018 Apr;217:158-166 (via https://www.ncbi.nlm.nih.gov/pubmed/29615249)
Most clade 2.3.4.4 H5NX subtype avian influenza viruses possess a T160A amino acid substitution in the hemagglutinin (HA) protein that has been shown to affect the receptor binding properties of a clade ... 5584 items, 20/Page, Page[164/280][|<<] [|<] [161] [162] [163] [164] [165] [166] [167] [168] [169] [170] [>|] [>>|] |
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