Kawano K, Hoshino T, Yano Y, Matsuzaki K. Steady dimer formation by the S31N mutant of influenza A virus M2 protein in living cell membranes. Biochim Biophys Acta Biomembr. 2025 Sep 9:184456. Abstract
submitted by kickingbird at Sep, 13, 2025 from Biochim Biophys Acta Biomembr. 2025 Sep 9:184456 (via https://www.sciencedirect.com/science/article/abs/pii/S00052)
The integral matrix protein M2 of the influenza A virus (H3N2) has been proposed to form a proton-selective channel, and is a target of the antiviral drug amantadine hydrochloride (Am). A significant increase ... Maya Sangesland et al. Functional, immunogenetic, and structural convergence in influenza immunity between humans and macaques. Sci. Transl. Med.17,eady3570(2025). Abstract
submitted by kickingbird at Sep, 13, 2025 from Sci. Transl. Med.17,eady3570(2025) (via https://www.science.org/doi/10.1126/scitranslmed.ady3570)
Human B cell immunity to the influenza hemagglutinin (HA) stem, a universal vaccine target, is often stereotyped and immunogenetically restricted, posing hurdles to study outside of humans. Here, we show ... Ruifeng Xu, Minhao Gao, Nailou Zhang, Zhenhua Wei,. [preprint]Transcontinental Spread of HPAI H5N1 from South America to Antarctica via Avian Vectors. https://doi.org/10.1101/2025.09.06.674605. Abstract
submitted by kickingbird at Sep, 12, 2025 from https://doi.org/10.1101/2025.09.06.674605 (via https://www.biorxiv.org/content/10.1101/2025.09.06.674605v1)
Our study has for the first time identified H5N1 strains (clade 2.3.4.4b, genotype B3.2) in brown skuas from the Fildes Peninsula, South Shetland Islands, Antarctica. These findings indicate that highly ... Antje Steinfurth, etc.,al. [preprint]Investigating high pathogenicity avian influenza virus incursions to remote islands: Detection of H5N1 on Gough Island in the South Atlantic Ocean. https://doi.org/10.1101/2025.09.06.674618. Abstract
submitted by kickingbird at Sep, 12, 2025 from https://doi.org/10.1101/2025.09.06.674618 (via https://www.biorxiv.org/content/10.1101/2025.09.06.674618v1)
Understanding the mechanisms underlying the emergence and spread of high pathogenicity avian influenza virus (HPAIV) is critical for tracking its global dissemination, particularly via migratory seabirds, ... Lan R, Yang J, Li J, Li H, Cao X, Tao M, Chang H,. Continuous evolution of Eurasian avian-like H1N1 swine influenza viruses with pdm/09-derived internal genes enhances pathogenicity in mice. J Virol. 2025 Sep 8:e0043025. Abstract
submitted by kickingbird at Sep, 11, 2025 from J Virol. 2025 Sep 8:e0043025 (via https://journals.asm.org/doi/10.1128/jvi.00430-25)
Swine influenza A virus (swIAV) is an important zoonotic pathogen with the potential to cause human influenza pandemics. Swine are considered "mixing vessels" for generating novel reassortant influenza ... Holly A. Coombes, etc.,al. [preprint]Infection of ratites with clade 2.3.4.4b HPAIV H5N1: Potential implications for zoonotic risk. https://doi.org/10.1101/2025.09.08.674895. Abstract
submitted by kickingbird at Sep, 11, 2025 from https://doi.org/10.1101/2025.09.08.674895 (via https://www.biorxiv.org/content/10.1101/2025.09.08.674895v1)
We detected H5N1 high pathogenicity avian influenza in captive Greater Rhea (Rhea americana). Viral genetic analysis revealed the mammalian associated PB2-E627K mutation, indicating selection of mammalian-relevant ... Zhu, Y., Sun, Y., Deng, X., Cao, P., Li, S., Yu, H. Matrix Protein 1 (M1) of Influenza A Virus: Structural and Functional Insights. Emerging Microbes & Infections. Abstract
submitted by kickingbird at Sep, 10, 2025 from Emerging Microbes & Infections (via https://www.tandfonline.com/doi/full/10.1080/22221751.2025.2)
Enveloped viruses rely on matrix proteins for structural integrity and lifecycle progression. Matrix protein 1 (M1) is the most abundant structural protein of influenza A virus (IAV), playing a multifaceted ... Chloe Stenkamp-Strahm, etc.,al. [preprint]Dairy Environments with Milk Exposure are Most Likely to Have Detection of Influenza A Virus. https://doi.org/10.1101/2025.09.03.25335023. Abstract
submitted by kickingbird at Sep, 9, 2025 from https://doi.org/10.1101/2025.09.03.25335023 (via https://www.medrxiv.org/content/10.1101/2025.09.03.25335023v)
Highly pathogenic avian influenza virus of the H5N1 subtype has been infecting U.S dairy cattle and spreading among dairy farms since March 2024. H5N1 surveillance systems for dairy farms are needed, but ... Chen P-L, Yang G, Ojha C, Banoth B, Russell CJ. Modification of H1N1 Influenza Luciferase Reporter Viruses Using StopGo Translation and/or Mouse-Adapted Mutations. Viruses. 2025; 17(9):1211. Abstract
submitted by kickingbird at Sep, 8, 2025 from Viruses. 2025; 17(9):1211 (via https://www.mdpi.com/1999-4915/17/9/1211)
Reporter viruses are valuable tools for studying infections at the cellular level and in living animals. They also enable rapid, high-throughput antiviral drug screening and serological studies. We previously ... Xia Y, Yuan J, Liu T, Zhang R, Wu C, Sui N, Li L,. TRPM2 knockdown alleviated H9N2 influenza virus infected ferroptosis in mouse pulmonary microvascular endothelial cells. Vet Microbiol. 2025 Sep 1;310:110703. Abstract
submitted by kickingbird at Sep, 6, 2025 from Vet Microbiol. 2025 Sep 1;310:110703 (via https://www.sciencedirect.com/science/article/abs/pii/S03781)
H9N2 influenza virus, a prevalent influenza A virus, causes acute lung injury through mitochondrial damage associated with oxidative stress. Transient receptor potential melastatin 2 (TRPM2) is a Ca2+ ... Jordan T. Ort, etc.,al. [preprint]Cross-reactive human antibody responses to H5N1 influenza virus neuraminidase are shaped by immune history. https://doi.org/10.1101/2025.09.02.25334929. Abstract
submitted by kickingbird at Sep, 5, 2025 from https://doi.org/10.1101/2025.09.02.25334929 (via https://www.medrxiv.org/content/10.1101/2025.09.02.25334929v)
H5N1 highly pathogenic avian influenza viruses have spread globally and pose a risk for a human pandemic. Prior studies suggest that early life exposures to group 1 influenza viruses (H1N1 and H2N2) prime ... Rute Maria Pinto, etc.,al. [preprint]The cow udder is a potential mixing vessel for influenza A viruses. https://doi.org/10.1101/2025.08.29.673079. Abstract
submitted by kickingbird at Sep, 4, 2025 from https://doi.org/10.1101/2025.08.29.673079 (via https://www.biorxiv.org/content/10.1101/2025.08.29.673079v1)
The incursion of high pathogenicity avian influenza A virus (IAV) into US dairy cows is unprecedented in the era of molecular diagnosis and pathogen sequencing. This raises questions over the likelihood ... Steve Leumi, etc.,al. [preprint]Cardioprotective effects of AMPK activation in H1N1 influenza virus infection. https://doi.org/10.1101/2025.08.28.672931. Abstract
submitted by kickingbird at Sep, 4, 2025 from https://doi.org/10.1101/2025.08.28.672931 (via https://www.biorxiv.org/content/10.1101/2025.08.28.672931v1)
Cardiac complications are among the most common and severe extrapulmonary manifestations of influenza virus infection, yet they are rarely recapitulated in mouse models without immunodeficiency. We found ... Feline F. W. Benavides, etc.,al. [preprint]Influenza A Virus Infection Impairs Neuronal Activity in Human iPSC-Derived NGN2 Neural Co-Cultures. https://doi.org/10.1101/2025.08.26.672266. Abstract
submitted by kickingbird at Sep, 4, 2025 from https://doi.org/10.1101/2025.08.26.672266 (via https://www.biorxiv.org/content/10.1101/2025.08.26.672266v1)
Influenza A virus (IAV) infection is associated with a wide variety of neurological complications, of which mild complications like impaired cognitive functioning are most prominent. Even though several ... Corrin, T., K. M. Young, M. Qamar, et al. A Rapid Review Contrasting the Evidence on Avian Influenza A(H5Nx) Clades 2.3.4.4b and 2.3.2.1c in Humans. Zoonoses and Public Health 1-34. Abstract
submitted by kickingbird at Sep, 4, 2025 from Zoonoses and Public Health 1-34 (via https://onlinelibrary.wiley.com/doi/10.1111/zph.70006)
Avian influenza viruses (AIV) circulate in wild and domestic bird populations, posing an on-going risk for zoonotic transmission and virus adaptation to mammals and humans. The A(H5Nx) clades 2.3.2.1c ... Nemoto M, Kawanishi N, Kamei R, Furusho K, Kawauch. Genetic and serological analyses of equine influenza viruses isolated in Kumamoto and Hokkaido, Japan in 2025. Vet Microbiol. 2025 Aug 30;310:110701. Abstract
submitted by kickingbird at Sep, 4, 2025 from Vet Microbiol. 2025 Aug 30;310:110701 (via https://www.sciencedirect.com/science/article/abs/pii/S03781)
In April and May 2025, outbreaks of equine influenza occurred for the first time in 17 years in Japan. Equine influenza virus (EIV) of the H3N8 subtype was mainly detected in heavy draft horse populations ... Wenhao O. Ouyang et al.. High-throughput synthesis and specificity characterization of natively paired influenza hemagglutinin antibodies with oPool+ display. Sci Transl Med . 2025 Sep 3;17(814):eadt4147. Abstract
submitted by kickingbird at Sep, 4, 2025 from Sci Transl Med . 2025 Sep 3;17(814):eadt4147 (via https://www.science.org/doi/10.1126/scitranslmed.adt4147)
Antibody discovery is crucial for developing therapeutics and vaccines and for understanding adaptive immunity. However, the lack of approaches to synthesize antibodies with defined sequences in a high-throughput ... Guinat C, Valenzuela Agüí C, Briand FX, Chakrabort. Poultry farm density and proximity drive highly pathogenic avian influenza spread. Commun Biol. 2025 Aug 29;8(1):1306. Abstract
submitted by kickingbird at Sep, 2, 2025 from Commun Biol. 2025 Aug 29;8(1):1306 (via https://www.nature.com/articles/s42003-025-08687-4)
The continuous spread of highly pathogenic avian influenza H5 viruses poses significant challenges, particularly in regions with high poultry farm densities where conventional control measures are less ... Liu Y, Yang Y, Quan K, Yin Y, Su X, Mao X, Yang H,. MDCK cell line expressing H9N2 avian influenza virus NS1 protein promotes replication of the NS1 gene truncation virus. Vet Microbiol. 2025 Aug 25;309:110694.. Abstract
submitted by kickingbird at Sep, 2, 2025 from Vet Microbiol. 2025 Aug 25;309:110694. (via https://www.sciencedirect.com/science/article/abs/pii/S03781)
H9N2 subtype avian influenza virus (AIV) remains a major threat to poultry industry. Our previously developed live-attenuated vaccine candidate rTX-NS1-128(mut) demonstrated promising immunogenicity, but ... Liu Y, Kj?r LJ, Boklund AE, Ward M, Nyegaard T, Ki. Modelling spillover risk of highly pathogenic avian influenza from wild birds to poultry in Denmark. Prev Vet Med. 2025 Aug 27;245:106669. Abstract
submitted by kickingbird at Sep, 2, 2025 from Prev Vet Med. 2025 Aug 27;245:106669 (via https://www.sciencedirect.com/science/article/pii/S016758772)
Spillover risks of contagious diseases affecting both wildlife and farm animals are of growing concern. Since late 2020, several waves of highly pathogenic avian influenza virus (HPAIV) clade 2.3.4.4b ... 6499 items, 20/Page, Page[15/325][|<<] [|<] [11] [12] [13] [14] [15] [16] [17] [18] [19] [20] [>|] [>>|] |
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