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2024-4-24 18:58:21
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Tonouchi K, Adachi Y, Suzuki T, Kuroda D, Nishiyam. Structural basis for cross-group recognition of an influenza virus hemagglutinin antibody that targets postfusion stabilized epitope. PLoS Pathog. 2023 Aug 9;19(8):e1011554.  Abstract  
submitted by kickingbird at Aug, 10, 2023 from PLoS Pathog. 2023 Aug 9;19(8):e1011554 (via https://journals.plos.org/plospathogens/article?id=10.1371/j)
Plasticity of influenza virus hemagglutinin (HA) conformation increases an opportunity to generate conserved non-native epitopes with unknown functionality. Here, we have performed an in-depth analysis ...

Xie Q, Liao X, Huang B, Wang L, Liao G, Luo C, Wen. The truncated IFITM3 facilitates the humoral immune response in inactivated influenza vaccine-vaccinated mice via interaction with CD81. Emerg Microbes Infect. 2023 Aug 9:2246599.  Abstract  
submitted by kickingbird at Aug, 10, 2023 from Emerg Microbes Infect. 2023 Aug 9:2246599 (via https://pubmed.ncbi.nlm.nih.gov/37556756/)
A single-nucleotide polymorphism (SNP) rs12252-C of interferon-induced transmembrane protein 3 (IFITM3), resulting in a truncated IFITM3 protein lacking 21 N-terminus amino acids, is associated with severe ...

Zeller MA, Ma J, Wong FY, Tum S, Hidano A, Holt H,. The genomic landscape of swine influenza A viruses in Southeast Asia. Proc Natl Acad Sci U S A. 2023 Aug 15;120(33):e230.  Abstract  
submitted by kickingbird at Aug, 9, 2023 from Proc Natl Acad Sci U S A. 2023 Aug 15;120(33):e230 (via https://www.pnas.org/doi/10.1073/pnas.2301926120)
Swine are a primary source for the emergence of pandemic influenza A viruses. The intensification of swine production, along with global trade, has amplified the transmission and zoonotic risk of swine ...

Tsang TK, Wang C, Fang VJ, Perera RAPM, So HC, Ip. Reconstructing household transmission dynamics to estimate the infectiousness of asymptomatic influenza virus infections. Proc Natl Acad Sci U S A. 2023 Aug 15;120(33):e230.  Abstract  
submitted by kickingbird at Aug, 8, 2023 from Proc Natl Acad Sci U S A. 2023 Aug 15;120(33):e230 (via https://www.pnas.org/doi/10.1073/pnas.2304750120)
There has long been controversy over the potential for asymptomatic cases of the influenza virus to have the capacity for onward transmission, but recognition of asymptomatic transmission of COVID-19 stimulates ...

Yang Y, Huang Y, Huang K, Zhang Y, Hu X, Zou W, Wu. Isolation and identification of Eurasian avian-like H1N1 swine influenza virus and evaluation of their pathogenicity and immune protective effects in pigs. Vet Microbiol. 2023 Jul 12;284:109827.  Abstract  
submitted by kickingbird at Aug, 7, 2023 from Vet Microbiol. 2023 Jul 12;284:109827 (via https://www.sciencedirect.com/science/article/abs/pii/S03781)
Swine influenza (SI) is a severe disease affecting pigs, with a huge economic impact on pig farmers. Currently, available SIV vaccines do not meet the requirements for Swine influenza prevention and control, ...

Xu S, Yu L, Teng Q, Li X, Jin Z, Qu Y, Li J, Zhang. Enhance immune response to H9 AIV DNA vaccine based on polygene expression and DGL nanoparticle encapsulation. Poult Sci. 2023 Jul 6;102(10):102925.  Abstract  
submitted by kickingbird at Aug, 7, 2023 from Poult Sci. 2023 Jul 6;102(10):102925 (via https://www.sciencedirect.com/science/article/pii/S003257912)
DNA vaccination has great potential to treat or prevent avian influenza pandemics, but the technique may be limited by low immunogenicity and gene delivery in clinical testing. Here, to improve the immune ...

Thompson D, Cismaru CV, Rougier JS, Schwemmle M, Z. The M2 proteins of bat influenza A viruses reveal atypical features compared to conventional M2 proteins. J Virol. 2023 Aug 4:e0038823.  Abstract  
submitted by kickingbird at Aug, 5, 2023 from J Virol. 2023 Aug 4:e0038823 (via https://journals.asm.org/doi/10.1128/jvi.00388-23)
The influenza A virus (IAV) M2 protein has proton channel activity, which plays a role in virus uncoating and may help to preserve the metastable conformation of the IAV hemagglutinin (HA). In contrast ...

Farrell A, Phan T, Brooke CB, Koelle K, Ke R. Semi-infectious particles contribute substantially to influenza virus within-host dynamics when infection is dominated by spatial structure. Virus Evol. 2023 Mar 21;9(1):vead020.  Abstract  
submitted by kickingbird at Aug, 5, 2023 from Virus Evol. 2023 Mar 21;9(1):vead020 (via https://academic.oup.com/ve/article/9/1/vead020/7117732)
Influenza is an ribonucleic acid virus with a genome that comprises eight segments. Experiments show that the vast majority of virions fail to express one or more gene segments and thus cannot cause a ...

Moreno G, Carbonell R, Díaz E, Martín-Loeches I, R. Effectiveness of prolonged versus standard-course of oseltamivir in critically ill patients with severe influenza infection: A multicentre cohort study. J Med Virol. 2023 Aug;95(8):e29010.  Abstract  
submitted by kickingbird at Aug, 5, 2023 from J Med Virol. 2023 Aug;95(8):e29010 (via https://onlinelibrary.wiley.com/doi/10.1002/jmv.29010)
The aim of this study is to investigate the effectiveness of prolonged versus standard course oseltamivir treatment among critically ill patients with severe influenza. A retrospective study of a prospectively ...

Mo J, Spackman E, Swayne DE. Prediction of highly pathogenic avian influenza vaccine efficacy in chickens by comparison of in vitro and in vivo data: A meta-analysis and systematic review. Vaccine. 2023 Aug 1:S0264-410X(23)00922-2.  Abstract  
submitted by kickingbird at Aug, 4, 2023 from Vaccine. 2023 Aug 1:S0264-410X(23)00922-2 (via https://www.sciencedirect.com/science/article/pii/S0264410X2)
Vaccines for avian influenza (AI) can protect poultry against disease, mortality, and virus transmission. Numerous factors, including: vaccine platform, immunogenicity, and relatedness to the field strain, ...

Zhou H, Liu J, Li L, Sun J, Wei Q, Huan Y, Carr MJ. Circulation of influenza C virus of C/Sao Paulo/378/82 lineage among pediatric acute respiratory cases, Shandong, China. Virology. 2023 Jul 27;587:109855.  Abstract  
submitted by kickingbird at Aug, 4, 2023 from Virology. 2023 Jul 27;587:109855 (via https://www.sciencedirect.com/science/article/abs/pii/S00426)
Influenza C virus (ICV) was identified in five pediatric acute respiratory cases in Shandong. Co-infection with other respiratory viruses was detected in four of these cases. Two ICV genomes were obtained ...

Zhu Z, Yang X, Huang C, Liu L. The Interferon-Induced Protein with Tetratricopeptide Repeats Repress Influenza Virus Infection by Inhibiting Viral RNA Synthesis. Viruses. 2023 Jun 22;15(7):1412.  Abstract  
submitted by kickingbird at Aug, 4, 2023 from Viruses. 2023 Jun 22;15(7):1412 (via https://www.mdpi.com/1999-4915/15/7/1412)
Influenza A virus (IAV) is an eight-segment negative-sense RNA virus and is subjected to gene recombination between strains to form novel strains, which may lead to influenza pandemics. Seasonal influenza ...

Markin A, Ciacci Zanella G, Arendsee ZW, Zhang J,. Reverse-zoonoses of 2009 H1N1 pandemic influenza A viruses and evolution in United States swine results in viruses with zoonotic potential. PLoS Pathog . 2023 Jul 27;19(7):e1011476.  Abstract  
submitted by kickingbird at Aug, 4, 2023 from PLoS Pathog . 2023 Jul 27;19(7):e1011476 (via https://journals.plos.org/plospathogens/article?id=10.1371/j)
The 2009 H1N1 pandemic (pdm09) lineage of influenza A virus (IAV) crosses interspecies barriers with frequent human-to-swine spillovers each year. These spillovers reassort and drift within swine populations, ...

Han AX, de Jong SPJ, Russell CA. Co-evolution of immunity and seasonal influenza viruses. Nat Rev Microbiol. 2023 Aug 2.  Abstract  
submitted by kickingbird at Aug, 4, 2023 from Nat Rev Microbiol. 2023 Aug 2 (via https://www.nature.com/articles/s41579-023-00945-8)
Seasonal influenza viruses cause recurring global epidemics by continually evolving to escape host immunity. The viral constraints and host immune responses that limit and drive the evolution of these ...

Cohen LE, Hansen CL, Andrew MK, McNeil SA, Vanhems. Predictors of severity of influenza-related hospitalizations: Results from the Global Influenza Hospital Surveillance Network (GIHSN). J Infect Dis. 2023 Aug 1:jiad303.  Abstract  
submitted by kickingbird at Aug, 2, 2023 from J Infect Dis. 2023 Aug 1:jiad303 (via https://academic.oup.com/jid/advance-article-abstract/doi/10)
Background: The Global Influenza Hospital Surveillance Network (GIHSN) has since 2012 provided patient-level data on severe influenza-like illnesses from over 100 participating clinical sites worldwide ...

Kent CM, Bevins SN, Mullinax JM, Sullivan JD, Pros. Waterfowl show spatiotemporal trends in influenza A H5 and H7 infections but limited taxonomic variation. Ecol Appl. 2023 Jul 31:e2906.  Abstract  
submitted by kickingbird at Aug, 1, 2023 from Ecol Appl. 2023 Jul 31:e2906 (via https://esajournals.onlinelibrary.wiley.com/doi/10.1002/eap.)
Influenza A viruses in wild birds pose threats to the poultry industry, wild birds, and human health under certain conditions. Of particular importance are wild waterfowl, which are the primary reservoir ...

Lim EH, Lim SI, Kim MJ, Kwon M, Kim MJ, Lee KB, Choe S, An DJ, Hyun BH, Park JY, Bae YC, Jeoung HY,. First Detection of Influenza D Virus Infection in Cattle and Pigs in the Republic of Korea. Microorganisms. 2023 Jul 5;11(7):1751.  Abstract  
submitted by kickingbird at Jul, 31, 2023 from Microorganisms. 2023 Jul 5;11(7):1751 (via https://www.mdpi.com/2076-2607/11/7/1751)
Influenza D virus (IDV) belongs to the Orthomyxoviridae family, which also include the influenza A, B and C virus genera. IDV was first detected and isolated in 2011 in the United States from pigs with ...

Kastner M, Karner A, Zhu R, Huang Q, Geissner A, S. Relevance of Host Cell Surface Glycan Structure for Cell Specificity of Influenza A Viruses. Viruses. 2023 Jul 5;15(7):1507.  Abstract  
submitted by kickingbird at Jul, 31, 2023 from Viruses. 2023 Jul 5;15(7):1507 (via https://www.mdpi.com/1999-4915/15/7/1507)
Influenza A viruses (IAVs) initiate infection via binding of the viral hemagglutinin (HA) to sialylated glycans on host cells. HA's receptor specificity towards individual glycans is well studied and clearly ...

Peng F, Xia Y, Li W. Prediction of Antigenic Distance in Influenza A Using Attribute Network Embedding. Viruses. 2023 Jun 29;15(7):1478.  Abstract  
submitted by kickingbird at Jul, 31, 2023 from Viruses. 2023 Jun 29;15(7):1478 (via https://www.mdpi.com/1999-4915/15/7/1478)
Owing to the rapid changes in the antigenicity of influenza viruses, it is difficult for humans to obtain lasting immunity through antiviral therapy. Hence, tracking the dynamic changes in the antigenicity ...

Lin M, Yao QC, Liu J, Huo M, Zhou Y, Chen M, Li Y,. Evolution and Reassortment of H6 Subtype Avian Influenza Viruses. Viruses. 2023 Jul 13;15(7):1547.  Abstract  
submitted by kickingbird at Jul, 31, 2023 from Viruses. 2023 Jul 13;15(7):1547 (via https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10383184/)
The H6 subtype of avian influenza virus (H6 AIV) is the most detected AIV subtype in poultry and wild birds. It causes economic losses to the poultry industry, and the most important, H6 AIV may have the ...

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