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2024-11-22 9:07:57
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Yang F, Zhao X, Huo C, Miao X, Qin T, Chen S, Peng. An avian-origin internal backbone effectively increases the H5 subtype avian influenza vaccine candidate yield in both chicken embryonated eggs and MDCK cells. Poult Sci. 2024 Jun 18;103(9):103988.  Abstract  
submitted by kickingbird at Jul, 7, 2024 from Poult Sci. 2024 Jun 18;103(9):103988 (via https://www.sciencedirect.com/science/article/pii/S003257912)
Inactivated vaccines play an important role in preventing and controlling the epidemic caused by the H5 subtype avian influenza virus. The vaccine strains are updated in response to alterations in surface ...

Panwar P, Jhala D, Tamrakar A, Joshi C, Patel A. Bacterially expressed full length Hemagglutinin of Avian Influenza Virus H5N1 forms oligomers and exhibits hemagglutination. Protein Expr Purif. 2024 Jul 4:106541.  Abstract  
submitted by kickingbird at Jul, 7, 2024 from Protein Expr Purif. 2024 Jul 4:106541 (via https://www.sciencedirect.com/science/article/abs/pii/S10465)
Avian influenza poses a significant global health threat, with the potential for widespread pandemics and devastating consequences. Hemagglutinin (HA), a critical surface glycoprotein of influenza viruses, ...

Ge FF, Shen HX, Yang DQ, Yang XC, Li X, Wang J, Hu. The biological characteristics and infection dynamics of a novel H3N2 canine influenza virus genotype in beagles. Virol J. 2024 Jul 4;21(1):151.  Abstract  
submitted by kickingbird at Jul, 5, 2024 from Virol J. 2024 Jul 4;21(1):151 (via https://virologyj.biomedcentral.com/articles/10.1186/s12985-)
Background: The canine influenza virus (CIV) outbreak has garnered considerable attention as it poses a significant threat to dog health. During the H3N2 CIV evolution in beagles, the virus formed a new ...

Luchansky JB, C S Porto-Fett A, Suarez DL, Spackma. Inactivation of Avian Influenza Virus Inoculated into Ground Beef Patties Cooked on a Commercial Open-Flame Gas Grill. J Food Prot. 2024 Jul 2:100325.  Abstract  
submitted by kickingbird at Jul, 5, 2024 from J Food Prot. 2024 Jul 2:100325 (via https://www.sciencedirect.com/science/article/pii/S0362028X2)
With the emergence of clade 2.3.4.4b H5N1 highly pathogenic avian influenza virus (AIV) infection of dairy cattle and its subsequent detection in raw milk, coupled with recent AIV infections affecting ...

Fan Yang, Xinyu Zhao, Chenzhi Huo, Xinyu Miao, Tao. An avian-origin internal backbone effectively increases the H5 subtype avian influenza vaccine candidate yield in both chicken embryonated eggs and MDCK cells. Poultry Science,2024,103988.  Abstract  
submitted by kickingbird at Jul, 4, 2024 from Poultry Science,2024,103988 (via https://www.sciencedirect.com/science/article/pii/S003257912)
Inactivated vaccines play an important role in preventing and controlling the epidemic caused by the H5 subtype avian influenza virus. The vaccine strains are updated in response to alterations in surface ...

Liang, Z., Lin, X., Sun, L. et al. A(H2N2) and A(H3N2) influenza pandemics elicited durable cross-reactive and protective antibodies against avian N2 neuraminidases. Nat Commun 15, 5593 (2024).  Abstract  
submitted by kickingbird at Jul, 4, 2024 from Nat Commun 15, 5593 (2024) (via https://www.nature.com/articles/s41467-024-49884-9)
Human cases of avian influenza virus (AIV) infections are associated with an age-specific disease burden. As the influenza virus N2 neuraminidase (NA) gene was introduced from avian sources during the ...

Chen W, Gu Y, Ma Y, Dong L, Pan L, Ji C, Guo L, Qi. Profiling lipid mediators in serum from children with H1N1 influenza. Sci Rep. 2024 Jul 2;14(1):15186.  Abstract  
submitted by kickingbird at Jul, 4, 2024 from Sci Rep. 2024 Jul 2;14(1):15186 (via https://www.nature.com/articles/s41598-024-66190-y)
Influenza A virus subtype H1N1 can cause severe acute respiratory distress syndrome and death in young children and elderly individuals. H1N1 initiates inflammatory responses that aim to contain and eliminate ...

de Carvalho Araujo A, Cho AY, Silva LMN, Corrêa TC. Mortality in sea lions is associated with the introduction of the H5N1 clade 2.3.4.4b virus in Brazil October 2023: whole genome sequencing and phylogenetic analysis. BMC Vet Res. 2024 Jul 2;20(1):285.  Abstract  
submitted by kickingbird at Jul, 4, 2024 from BMC Vet Res. 2024 Jul 2;20(1):285 (via https://bmcvetres.biomedcentral.com/articles/10.1186/s12917-)
Clade 2.3.4.4b highly pathogenic avian influenza (HPAI) H5N1 virus was detected in the South American sea lions found dead in Santa Catarina, Brazil, in October 2023. Whole genome sequencing and comparative ...

Spackman E, Jones DR, McCoig AM, Colonius TJ, Gora. Characterization of highly pathogenic avian influenza virus in retail dairy products in the US. J Virol. 2024 Jul 3:e0088124.  Abstract  
submitted by kickingbird at Jul, 4, 2024 from J Virol. 2024 Jul 3:e0088124 (via https://journals.asm.org/doi/10.1128/jvi.00881-24)
In March 2024, clade 2.3.4.4b H5N1 highly pathogenic avian influenza virus (HPAIV) was detected in dairy cattle in the US, and it was discovered that the virus could be detected in raw milk. Although affected ...

Zath GK, Thomas MM, Loveday EK, Bikos DA, Sanche S. Influenza A viral burst size from thousands of infected single cells using droplet quantitative PCR (dqPCR). PLoS Pathog. 2024 Jul 1;20(7):e1012257.  Abstract  
submitted by kickingbird at Jul, 4, 2024 from PLoS Pathog. 2024 Jul 1;20(7):e1012257 (via https://journals.plos.org/plospathogens/article?id=10.1371/j)
An important aspect of how viruses spread and infect is the viral burst size, or the number of new viruses produced by each infected cell. Surprisingly, this value remains poorly characterized for influenza ...

Marina R. Good, etc.,al. [preprint]A single mutation in dairy cow-associated H5N1 viruses increases receptor binding breadth. https://doi.org/10.1101/2024.06.22.600211.  Abstract  
submitted by kickingbird at Jul, 1, 2024 from https://doi.org/10.1101/2024.06.22.600211 (via https://www.biorxiv.org/content/10.1101/2024.06.22.600211v1)
Clade 2.3.4.4b H5N1 is causing an unprecedented outbreak in dairy cows in the United States. To understand if recent H5N1 viruses are changing their receptor use, we screened recombinant hemagglutinin ...

Erica Spackman, etc.,al. Inactivation of highly pathogenic avian influenza virus with high temperature short time 2 continuous flow pasteurization and virus detection in bulk milk tanks. USFDA.  Abstract  
submitted by kickingbird at Jul, 1, 2024 from USFDA (via https://www.fda.gov/media/179708/download?attachment)
Infections of dairy cattle with clade 2.3.4.4b H5N1 highly pathogenic avian influenza virus (HPAIV) were reported in March 2024 in the U.S. and viable virus was detected at high levels in raw milk from ...

Matsuzaki Y, Sugawara K, Kidoguchi Y, Kadowaki Y,. Genetic Reassortment in a Child Coinfected with Two Influenza B Viruses, B/Yamagata Lineage and B/Victoria-Lineage Strains. Viruses. 2024 Jun 19;16(6):983.  Abstract  
submitted by kickingbird at Jun, 28, 2024 from Viruses. 2024 Jun 19;16(6):983 (via https://www.mdpi.com/1999-4915/16/6/983)
We identified a child coinfected with influenza B viruses of B/Yamagata and B/Victoria lineages, in whom we analyzed the occurrence of genetic reassortment. Plaque purification was performed using a throat ...

Guo X, Zhou Y, Yan H, An Q, Liang C, Liu L, Qian J. Molecular Markers and Mechanisms of Influenza A Virus Cross-Species Transmission and New Host Adaptation. Viruses. 2024 May 30;16(6):88.  Abstract  
submitted by kickingbird at Jun, 28, 2024 from Viruses. 2024 May 30;16(6):88 (via https://www.mdpi.com/1999-4915/16/6/883)
Influenza A viruses continue to be a serious health risk to people and result in a large-scale socio-economic loss. Avian influenza viruses typically do not replicate efficiently in mammals, but through ...

Warren CJ, Brookes SM, Arnold ME, Irvine RM, Hanse. Assessment of Survival Kinetics for Emergent Highly Pathogenic Clade 2.3.4.4 H5Nx Avian Influenza Viruses. Viruses. 2024 May 31;16(6):889.  Abstract  
submitted by kickingbird at Jun, 28, 2024 from Viruses. 2024 May 31;16(6):889 (via https://www.mdpi.com/1999-4915/16/6/889)
High pathogenicity avian influenza viruses (HPAIVs) cause high morbidity and mortality in poultry species. HPAIV prevalence means high numbers of infected wild birds could lead to spill over events for ...

Bordes L, Gerhards NM, Peters S, van Oort S, Roose. H5N1 clade 2.3.4.4b avian influenza viruses replicate in differentiated bovine airway epithelial cells cultured at air-liquid interface. J Gen Virol. 2024 Jun;105(6).  Abstract  
submitted by kickingbird at Jun, 27, 2024 from J Gen Virol. 2024 Jun;105(6) (via https://www.microbiologyresearch.org/content/journal/jgv/10.)
Highly pathogenic avian influenza (HPAI) H5N1 viruses are responsible for disease outbreaks in wild birds and poultry, resulting in devastating losses to the poultry sector. Since 2020, an increasing number ...

Tang J, Zou SM, Zhou JF, Gao RB, Xin L, Zeng XX, H. R229I substitution from oseltamivir induction in HA1 region significantly increased the fitness of a H7N9 virus bearing NA 292K. Emerg Microbes Infect. 2024 Jun 26:2373314.  Abstract  
submitted by kickingbird at Jun, 27, 2024 from Emerg Microbes Infect. 2024 Jun 26:2373314 (via https://www.tandfonline.com/doi/full/10.1080/22221751.2024.2)
The proportion of human isolates with reduced neuraminidase inhibitors (NAIs) susceptibility in highly pathogenic avian influenza (HPAI) H7N9 virus was as high as 13%. These drug-resistant strains showed ...

Zhang X, Zhang Y, Wei F. Research progress on the nonstructural protein 1 (NS1) of influenza a virus. Virulence. 2024 Dec;15(1):2359470.  Abstract  
submitted by kickingbird at Jun, 27, 2024 from Virulence. 2024 Dec;15(1):2359470 (via https://www.tandfonline.com/doi/full/10.1080/21505594.2024.2)
Influenza A virus (IAV) is the leading cause of highly contagious respiratory infections, which poses a serious threat to public health. The non-structural protein 1 (NS1) is encoded by segment 8 of IAV ...

Chatzilena A, Hyams C, Challen R, Marlow R, King J. Winter 2022-23 influenza vaccine effectiveness against influenza-related hospitalised aLRTD: A test-negative, case-control study. Vaccine. 2024 Jun 24:S0264-410X(24)00713-8.  Abstract  
submitted by kickingbird at Jun, 27, 2024 from Vaccine. 2024 Jun 24:S0264-410X(24)00713-8 (via https://www.sciencedirect.com/science/article/abs/pii/S02644)
BackgroundInfluenza activity in the UK started early during the winter 2022–23 season, with most surveillance systems reporting high levels of hospitalisation, intensive care unit influenza admission and ...

Marina R. Good, etc.,al. [preprint]A single mutation in dairy cow-associated H5N1 viruses increases receptor binding breadth. https://doi.org/10.1101/2024.06.22.600211.  Abstract  
submitted by kickingbird at Jun, 25, 2024 from https://doi.org/10.1101/2024.06.22.600211 (via https://www.biorxiv.org/content/10.1101/2024.06.22.600211v1)
Clade 2.3.4.4b H5N1 is causing an unprecedented outbreak in dairy cows in the United States. To understand if recent H5N1 viruses are changing their receptor use, we screened recombinant hemagglutinin ...

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