Hu X, Saxena A, Magstadt DR, Gauger PC, Burrough E. Genomic Characterization of Highly Pathogenic Avian Influenza A H5N1 Virus Newly Emerged in Dairy Cattle. Emerg Microbes Infect. 2024 Jul 15:2380421. Abstract
submitted by kickingbird at Jul, 16, 2024 from Emerg Microbes Infect. 2024 Jul 15:2380421 (via https://www.tandfonline.com/doi/full/10.1080/22221751.2024.2)
In March 2024, the emergence of highly pathogenic avian influenza (HPAI) A (H5N1) infections in dairy cattle was detected in United States for the first time. We genetically characterize HPAI viruses from ... Roach SN, Shepherd FK, Mickelson CK, Fiege JK, Thi. Tropism for ciliated cells is the dominant driver of influenza viral burst size in the human airway. PNAS 2024 Jul 30;121(31):e2320303121. Abstract
submitted by kickingbird at Jul, 16, 2024 from PNAS 2024 Jul 30;121(31):e2320303121 (via https://www.pnas.org/doi/10.1073/pnas.2320303121)
Influenza viruses pose a significant burden on global human health. Influenza has a broad cellular tropism in the airway, but how infection of different epithelial cell types impacts replication kinetics ... Jiayun Yang, etc.,al. [preprint]The Haemagglutinin Genes of the UK Clade 2.3.4.4b H5N1 Avian Influenza Viruses from 2020 to 2022 Retain Strong Avian Phenotype. https://doi.org/10.1101/2024.07.09.602706. Abstract
submitted by kickingbird at Jul, 15, 2024 from https://doi.org/10.1101/2024.07.09.602706 (via https://www.biorxiv.org/content/10.1101/2024.07.09.602706v1)
Since 2020, the United Kingdom (UK) has suffered repeated epizootics of clade 2.3.4.4b H5 high pathogenicity avian influenza viruses (HPAIVs) in wild birds and poultry, resulting in substantial economic ... Ryota Tanaka, etc.,al. [preprint]In vitro one-pot construction of influenza viral genomes for virus particle synthesis based on reverse genetics system. https://doi.org/10.1101/2024.07.12.603202. Abstract
submitted by kickingbird at Jul, 14, 2024 from https://doi.org/10.1101/2024.07.12.603202 (via https://www.biorxiv.org/content/10.1101/2024.07.12.603202v1)
The reverse genetics system, which allows the generation of influenza viruses from plasmids encoding viral genome, is a powerful tool for basic research on viral infection mechanisms and application research ... Amy L. Baker, etc.,al. [preprint]Experimental reproduction of viral replication and disease in dairy calves and lactating cows inoculated with highly pathogenic avian influenza H5N1 clade 2.3.4.4b. https://doi.org/10.1101/2024.07.12.603337. Abstract
submitted by kickingbird at Jul, 14, 2024 from https://doi.org/10.1101/2024.07.12.603337 (via https://www.biorxiv.org/content/10.1101/2024.07.12.603337v1)
Highly pathogenic avian influenza (HPAI) H5N1 of the hemagglutinin clade 2.3.4.4b was detected in the United States in late 2021 and continues to circulate in all four North American flyways to date. In ... Hang Gong, Ganping Cai, Chunyan Chen, Feng Chen, C. Construction of a monoclonal molecular imprinted sensor with high affinity for specific recognition of influenza A virus subtype. Talanta 2024, 126568. Abstract
submitted by kickingbird at Jul, 14, 2024 from Talanta 2024, 126568 (via https://www.sciencedirect.com/science/article/abs/pii/S00399)
Although molecular imprinting technology has been widely used in the construction of virus sensors, it is still a great challenge to identify subtypes viruses specifically because of their high similarity ... Shubin Li, Xuebin Peng, MinJie Wang, Wenqian Wa. Influenza A Virus Utilizes the Nasolacrimal System to Establish Respiratory Infection after Ocular Exposure in the Swine Model. Transboundary and Emerging Diseases Vol 2024. Abstract
submitted by kickingbird at Jul, 14, 2024 from Transboundary and Emerging Diseases Vol 2024 (via https://onlinelibrary.wiley.com/doi/10.1155/2024/8192499)
Influenza A virus (IAV) can rapidly disseminate among animals through various transmission routes, with emerging evidence suggesting the ocular surface as an important entrance. However, it remains unclear ... Minghui Li, etc.,al. Spatiotemporal and Species-Crossing Transmission Dynamics of Subclade 2.3.4.4b H5Nx HPAIVs. Transboundary and Emerging Diseases Vol 2024. Abstract
submitted by kickingbird at Jul, 14, 2024 from Transboundary and Emerging Diseases Vol 2024 (via https://onlinelibrary.wiley.com/doi/10.1155/2024/2862053)
Subclade 2.3.4.4b H5Nx highly pathogenic avian influenza (HPAI) viruses, emerged in 2013 with multiple subtypes of H5N8, H5N1, and H5N6, had unprecedently caused a global epizootic by H5N1 since 2021, ... Konstantin Andreev, Jeremy C. Jones, Patrick Seile. Genotypic and phenotypic susceptibility of emerging avian influenza A viruses to neuraminidase and cap-dependent endonuclease inhibitors. Antiviral Research, 2024, 105959. Abstract
submitted by kickingbird at Jul, 14, 2024 from Antiviral Research, 2024, 105959 (via https://www.sciencedirect.com/science/article/pii/S016635422)
Avian influenza outbreaks, including ones caused by highly pathogenic A(H5N1) clade 2.3.4.4b viruses, have devastated animal populations and remain a threat to humans. Risk elements assessed for emerging ... Cassidy N.G. Erdelyan, Ahmed Kandeil, Anthony V. S. Multiple transatlantic incursions of highly pathogenic avian influenza clade 2.3.4.4b A(H5N5) virus into North America and spillover to mammals. Cell Reports, Vol 43, Issue 7, 2024, 114479. Abstract
submitted by kickingbird at Jul, 14, 2024 from Cell Reports, Vol 43, Issue 7, 2024, 114479 (via https://www.sciencedirect.com/science/article/pii/S221112472)
Highly pathogenic avian influenza (HPAI) viruses have spread at an unprecedented scale, leading to mass mortalities in birds and mammals. In 2023, a transatlantic incursion of HPAI A(H5N5) viruses into ... Chowdhury D, Nayeem M, Vanderven HA, Sarker S. Role of miRNA in Highly Pathogenic H5 Avian Influenza Virus Infection: An Emphasis on Cellular and Chicken Models. Viruses. 2024; 16(7):1102. Abstract
submitted by kickingbird at Jul, 14, 2024 from Viruses. 2024; 16(7):1102 (via https://www.mdpi.com/1999-4915/16/7/1102)
The avian influenza virus, particularly the H5N1 strain, poses a significant and ongoing threat to both human and animal health. Recent outbreaks have affected domestic and wild birds on a massive scale, ... de Vos CJ, Elbers ARW. Quantitative Risk Assessment of Wind-Supported Transmission of Highly Pathogenic Avian Influenza Virus to Dutch Poultry Farms via Fecal Particles from Infected Wild Birds in the Environment. Pathogens. 2024; 13(7):571. Abstract
submitted by kickingbird at Jul, 14, 2024 from Pathogens. 2024; 13(7):571 (via https://www.mdpi.com/2076-0817/13/7/571)
A quantitative microbial risk assessment model was developed to estimate the probability that the aerosolization of fecal droppings from wild birds in the vicinity of poultry farms would result in the ... Zhao Y, Han L, Sang H, Liu S, Yang P, Hou Y, Xiao. Swine Influenza Viruses Isolated from 2019 to 2022 in Shandong Province, China, Exemplify the Dominant Genotype. Genes. 2024; 15(7):849. Abstract
submitted by kickingbird at Jul, 14, 2024 from Genes. 2024; 15(7):849 (via https://www.mdpi.com/2073-4425/15/7/849)
Swine influenza viruses (SIVs) have been circulating in swine globally and are potential threats to human health. During the surveillance of SIVs in Shandong Province, China, from 2019 to 2022, 21 reassortant ... Graaf-Rau A, Schmies K, Breithaupt A, Ciminski K,. Reassortment incompetent live attenuated and replicon influenza vaccines provide improved protection against influenza in piglets. NPJ Vaccines. 2024 Jul 13;9(1):127. Abstract
submitted by kickingbird at Jul, 14, 2024 from NPJ Vaccines. 2024 Jul 13;9(1):127 (via https://www.nature.com/articles/s41541-024-00916-x)
Swine influenza A viruses (swIAV) cause an economically important respiratory disease in modern pig production. Continuous virus transmission and antigenic drift are difficult to control in enzootically ... Chen D, Su W, Choy KT, Chu YS, Lin CH, Yen HL. High throughput profiling identified PA-L106R amino acid substitution in A(H1N1)pdm09 influenza virus that confers reduced susceptibility to baloxavir in vitro. Antiviral Res. 2024 Jul 11:105961. Abstract
submitted by kickingbird at Jul, 14, 2024 from Antiviral Res. 2024 Jul 11:105961 (via https://www.sciencedirect.com/science/article/pii/S016635422)
Baloxavir acid (BXA) is a pan-influenza antiviral that targets the cap-dependent endonuclease of the polymerase acidic (PA) protein required for viral mRNA synthesis. To gain a comprehensive understanding ... Fan Q, Xie Z, Zhao J, Hua J, Wei Y, Li X, Li D, Lu. Simultaneous differential detection of H5, H7 and H9 subtypes of avian influenza viruses by a triplex fluorescence loop-mediated isothermal amplification assay. Front. Vet. Sci. 11:1419312. Abstract
submitted by kickingbird at Jul, 14, 2024 from Front. Vet. Sci. 11:1419312 (via https://www.frontiersin.org/journals/veterinary-science/arti)
H5, H7, and H9 are pivotal avian influenza virus (AIV) subtypes that cause substantial economic losses and pose potential threats to public health worldwide. In this study, a novel triplex fluorescence ... Andreev K, Jones JC, Seiler P, Kandeil A, Webby RJ. Genotypic and phenotypic susceptibility of emerging avian influenza A viruses to neuraminidase and cap-dependent endonuclease inhibitors. Antiviral Res. 2024 Jul 8:105959. Abstract
submitted by kickingbird at Jul, 12, 2024 from Antiviral Res. 2024 Jul 8:105959 (via https://www.sciencedirect.com/science/article/pii/S016635422)
Avian influenza outbreaks, including ones caused by highly pathogenic A(H5N1) clade 2.3.4.4b viruses, have devastated animal populations and remain a threat to humans. Risk elements assessed for emerging ... Ahrens AK, Pohlmann A, Grund C, Harder T, Beer M. Novel Genotypes of Highly Pathogenic Avian Influenza H5N1 Clade 2.3.4.4b Viruses, Germany, November 2023. Emerg Infect Dis. 2024 Aug. Abstract
submitted by kickingbird at Jul, 12, 2024 from Emerg Infect Dis. 2024 Aug (via https://wwwnc.cdc.gov/eid/article/30/8/24-0103_article)
Several subtypes and many different genotypes of highly pathogenic avian influenza viruses of subtype H5 clade 2.3.4.4b have repeatedly caused outbreaks in Germany. Four new highly pathogenic avian influenza ... James J, Thomas SS, Seekings AH, Mahmood S, Kelly. Evaluating the epizootic and zoonotic threat of an H7N9 low-pathogenicity avian influenza virus (LPAIV) variant associated with enhanced pathogenicity in turkeys. J Gen Virol. 2024 Jul;105(7). Abstract
submitted by kickingbird at Jul, 10, 2024 from J Gen Virol. 2024 Jul;105(7) (via https://www.microbiologyresearch.org/content/journal/jgv/10.)
Between 2013 and 2017, the A/Anhui/1/13-lineage (H7N9) low-pathogenicity avian influenza virus (LPAIV) was epizootic in chickens in China, causing mild disease, with 616 fatal human cases. Despite poultry ... Yang Q, Ji J, Yang J, Zhang Y, Yin H, Dai H, Wang. Diversity of genotypes and pathogenicity of H9N2 avian influenza virus derived from wild bird and domestic poultry. Front. Microbiol. 15:1402235. Abstract
submitted by kickingbird at Jul, 9, 2024 from Front. Microbiol. 15:1402235 (via https://www.frontiersin.org/journals/microbiology/articles/1)
Introduction: The H9N2 subtype is a predominant avian influenza virus (AIV) circulating in Chinese poultry, forming various genotypes (A-W) based on gene segment origins. This study aims to investigate ... 5584 items, 20/Page, Page[14/280][|<<] [|<] [11] [12] [13] [14] [15] [16] [17] [18] [19] [20] [>|] [>>|] |
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