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2024-7-18 3:36:40
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Louisa E. Sjaastad, Elizabeth J. Fay, Jessica K. F. Distinct antiviral signatures revealed by the magnitude and round of influenza virus replication in vivo. PNAS September 18, 2018 115 (38) 9610-9615.  Abstract  
submitted by kickingbird at Sep, 20, 2018 from PNAS September 18, 2018 115 (38) 9610-9615 (via http://www.pnas.org/content/115/38/9610)
Influenza virus has a broad cellular tropism in the respiratory tract. Infected epithelial cells sense the infection and initiate an antiviral response. To define the antiviral response at the earliest ...

Astill J, etc.,al. A Comparison of Toll-Like Receptor 5 and 21 Ligands as Adjuvants for a Formaldehyde Inactivated H9N2 Avian Influenza Virus Vaccine in Chickens. Viral Immunol. 2018 Sep 15..  Abstract  
submitted by kickingbird at Sep, 20, 2018 from Viral Immunol. 2018 Sep 15. (via https://www.ncbi.nlm.nih.gov/pubmed/30222508)
Low pathogenic avian influenza virus (AIV) infection in chickens can result in economic losses and has impacts on human health. Poultry vaccination is a tool that can be used to decrease infection and ...

Poolkhet C, etc.,al. Exponential random graph models to evaluate the movement of backyard chickens after the avian influenza crisis in 2004~2005, Thailand. Prev Vet Med. 2018 Oct 1;158:71-77..  Abstract  
submitted by kickingbird at Sep, 20, 2018 from Prev Vet Med. 2018 Oct 1;158:71-77. (via https://www.ncbi.nlm.nih.gov/pubmed/30220398)
The aim of this study was to use exponential random graph models (ERGMs) to explain networks of movement of backyard chickens in provinces which had been hotspots for avian influenza outbreaks in Thailand ...

Phillips AM, etc.,al. Destabilized adaptive influenza variants critical for innate immune system escape are potentiated by host chaperones. PLoS Biol. 2018 Sep 17;16(9):e3000008.  Abstract  
submitted by kickingbird at Sep, 20, 2018 from PLoS Biol. 2018 Sep 17;16(9):e3000008 (via https://www.ncbi.nlm.nih.gov/pubmed/30222731)
The threat of viral pandemics demands a comprehensive understanding of evolution at the host-pathogen interface. Here, we show that the accessibility of adaptive mutations in influenza nucleoprotein at ...

Treurnicht FK, etc.,al. Replacement of neuraminidase inhibitor susceptible influenza A(H1N1) with resistant phenotype in 2008 and circulation of susceptible influenza A and B viruses during 2009-2013, South Africa. Influenza Other Respir Viruses. 2018 Sep 14..  Abstract  
submitted by kickingbird at Sep, 20, 2018 from Influenza Other Respir Viruses. 2018 Sep 14. (via https://www.ncbi.nlm.nih.gov/pubmed/30218485)
BACKGROUND: Data on the susceptibility of influenza viruses from South Africa to neuraminidase inhibitors (NAIs) is scarce, and no extensive analysis was done.OBJECTIVES: We aimed to determine oseltamivir ...

Neyer VL, Woo JG, Siegel RM. Severe Obesity in Children May Not Pose Independent Risk for Influenza Complications. J Pediatr Nurs. 2018 Sep - Oct;42:21-24.  Abstract  
submitted by kickingbird at Sep, 20, 2018 from J Pediatr Nurs. 2018 Sep - Oct;42:21-24 (via https://www.ncbi.nlm.nih.gov/pubmed/30219295)
PURPOSE: Subsets of children are targeted for influenza vaccination due to known conditions that increase the risk of influenza complications. The purpose of this study was to determine if severe obesity ...

Abed Y, etc.,al. Comparison of early and recent influenza A(H1N1)pdm09 isolates harboring or not the H275Y neuraminidase mutation, in vitro and in animal models. Antiviral Res. 2018 Sep 13..  Abstract  
submitted by kickingbird at Sep, 20, 2018 from Antiviral Res. 2018 Sep 13. (via https://www.ncbi.nlm.nih.gov/pubmed/30219318)
After 6 years of circulation in humans, a novel antigenic variant of influenza A(H1N1)pdm09 (i.e., A/Michigan/45/2015) emerged in 2015-16 and has predominated thereafter worldwide. Herein, we compared ...

Bolton MJ, etc.,al. Antigenic evolution of H3N2 influenza A viruses in swine in the United States from 2012 to 2016. Influenza Other Respir Viruses. 2018 Sep 14.  Abstract  
submitted by kickingbird at Sep, 20, 2018 from Influenza Other Respir Viruses. 2018 Sep 14 (via https://www.ncbi.nlm.nih.gov/pubmed/30216671)
BACKGROUND: Six amino acid positions (145, 155, 156, 158, 159 and 189, referred to as the antigenic motif; H3 numbering) in the globular head region of hemagglutinin (HA1 domain) play an important role ...

Garnacho-Montero J, etc.,al. Clinical characteristics, evolution, and treatment-related risk factors for mortality among immunosuppressed patients with influenza A (H1N1) virus admitted to the intensive care unit.. J Crit Care. 2018 Aug 24;48:172-177..  Abstract  
submitted by kickingbird at Sep, 20, 2018 from J Crit Care. 2018 Aug 24;48:172-177. (via https://www.ncbi.nlm.nih.gov/pubmed/30216935)
PURPOSE: Information about immunocompromised patients infected with influenza A (H1N1) virus and requiring admission to the ICU is lacking. Our objective was to know the clinical characteristics of these ...

Mostafa A, Abdelwhab EM, Mettenleiter TC. Zoonotic Potential of Influenza A Viruses: A Comprehensive Overview. Viruses. 2018 Sep 13;10(9).  Abstract  
submitted by kickingbird at Sep, 20, 2018 from Viruses. 2018 Sep 13;10(9) (via https://www.ncbi.nlm.nih.gov/pubmed/30217093)
Influenza A viruses (IAVs) possess a great zoonotic potential as they are able to infect different avian and mammalian animal hosts, from which they can be transmitted to humans. This is based on the ability ...

Hewei Zhang, etc.,al. Influenza C Virus in Cattle with Respiratory Disease, United States, 2016~2018. EID,Vol 24, Issue 10 Oct 2018.  Abstract  
submitted by kickingbird at Sep, 18, 2018 from EID,Vol 24, Issue 10 Oct 2018 (via https://wwwnc.cdc.gov/eid/article/24/10/18-0589_article)
We identified influenza C virus (ICV) in samples from US cattle with bovine respiratory disease through real-time PCR testing and sequencing. Bovine ICV isolates had high nucleotide identities (≈98%) with ...

Andrew M. Ramey, etc.,al. Introduction of Eurasian-Origin Influenza A(H8N4) Virus into North America by Migratory Birds. EID,Vol 24, Issue 10 Oct 2018.  Abstract  
submitted by kickingbird at Sep, 18, 2018 from EID,Vol 24, Issue 10 Oct 2018 (via https://wwwnc.cdc.gov/eid/article/24/10/18-0447_article)
We identified a Eurasian-origin influenza A(H8N4) virus in North America by sampling wild birds in western Alaska, USA. Evidence for repeated introductions of influenza A viruses into North America by ...

Jung-Hoon Kwon, etc.,al. New Reassortant Clade 2.3.4.4b Avian Influenza A(H5N6) Virus in Wild Birds, South Korea, 2017~18. EID,Vol 24, Issue 10 Oct 2018.  Abstract  
submitted by kickingbird at Sep, 18, 2018 from EID,Vol 24, Issue 10 Oct 2018 (via https://wwwnc.cdc.gov/eid/article/24/10/18-0461_article)
We isolated new reassortant avian influenza A(H5N6) viruses from feces of wild waterfowl in South Korea during 2017–18. Phylogenetic analysis suggested that reassortment occurred between clade 2.3.4.4b ...

Masato Hatta, etc.,al. Effectiveness of Whole, Inactivated, Low Pathogenicity Influenza A(H7N9) Vaccine against Antigenically Distinct, Highly Pathogenic H7N9 Virus. EID,Vol 24, Issue 10 Oct 2018.  Abstract  
submitted by kickingbird at Sep, 18, 2018 from EID,Vol 24, Issue 10 Oct 2018 (via https://wwwnc.cdc.gov/eid/article/24/10/18-0403_article)
The recent emergence of highly pathogenic influenza A(H7N9) variants poses a great risk to humans. We show that ferrets vaccinated with low pathogenicity H7N9 virus vaccine do not develop severe symptoms ...

Zhu C, etc.,al. System for the heterologous expression of NS1 protein of H9N2 avian influenza virus in the ciliate Tetrahymena thermophila. J Vet Med Sci. 2018 Sep 11.  Abstract  
submitted by kickingbird at Sep, 16, 2018 from J Vet Med Sci. 2018 Sep 11 (via https://www.ncbi.nlm.nih.gov/pubmed/30210069)
Tetrahymena is commonly used as an alternative eukaryotic system for efficiently expressing heterologous genes. In this study, we inserted the non-structural (NS) 1 gene of avian influenza virus (AIV) ...

Dunina-Barkovskaya AY, etc.,al. Amphipathic CRAC-Containing Peptides Derived from the Influenza Virus A M1 Protein Modulate Cholesterol-Dependent Activity of Cultured IC-21 Macrophages. Biochemistry (Mosc). 2018 Aug;83(8):982-991.  Abstract  
submitted by kickingbird at Sep, 16, 2018 from Biochemistry (Mosc). 2018 Aug;83(8):982-991 (via https://www.ncbi.nlm.nih.gov/pubmed/30208834)
Entry of many viral and bacterial pathogens into host cells depends on cholesterol and/or cholesterol-enriched domains (lipid rafts) in the cell membrane. Earlier, we showed that influenza virus A matrix ...

Marché S, van den Berg T, Lambrecht B. Domestic canaries (Serinus canaria forma domestica) are susceptible to Low Pathogenic Avian Influenza virus infections. Avian Pathol. 2018 Sep 12:0.  Abstract  
submitted by kickingbird at Sep, 16, 2018 from Avian Pathol. 2018 Sep 12:0 (via https://www.ncbi.nlm.nih.gov/pubmed/30207746)
Avian influenza viruses have been isolated from many bird species; however, little is known about the susceptibility of pet birds to low pathogenic avian influenza (LPAI) viruses. To address this research ...

Kawaguchi N, Koshimichi H, Ishibashi T, Wajima T. Evaluation of Drug-Drug Interaction Potential between Baloxavir Marboxil and Oseltamivir in Healthy Subjects. Clin Drug Investig. 2018 Sep 10..  Abstract  
submitted by kickingbird at Sep, 16, 2018 from Clin Drug Investig. 2018 Sep 10. (via https://www.ncbi.nlm.nih.gov/pubmed/30203386)
BACKGROUND AND OBJECTIVE: Baloxavir marboxil is a prodrug that is metabolized to baloxavir acid, which suppresses viral replication by inhibiting cap-dependent endonuclease with a single oral administration. ...

Krone O, Globig A, Ulrich R, Harder T, etc.,al. White-Tailed Sea Eagle (Haliaeetus albicilla) Die-Off Due to Infection with Highly Pathogenic Avian Influenza Virus, Subtype H5N8, in Germany. Viruses. 2018 Sep 7;10(9).  Abstract  
submitted by kickingbird at Sep, 16, 2018 from Viruses. 2018 Sep 7;10(9) (via https://www.ncbi.nlm.nih.gov/pubmed/30205456)
In contrast to previous incursions of highly pathogenic avian influenza (HPAIV) H5 viruses, H5N8 clade 2.3.4.4b viruses caused numerous cases of lethal infections in white-tailed sea eagles (Haliaeetus ...

Yang W, Yin X, Guan L, Li M, Ma S, Shi J. A live attenuated vaccine prevents replication and transmission of H7N9 highly pathogenic influenza viruses in mammals. Emerg Microbes Infect. 2018 Sep 12;7(1):153.  Abstract  
submitted by kickingbird at Sep, 16, 2018 from Emerg Microbes Infect. 2018 Sep 12;7(1):153 (via https://www.ncbi.nlm.nih.gov/pubmed/30206210)
H7N9 influenza viruses emerged in 2013 and have caused severe disease and deaths in humans in China. Some H7N9 viruses circulating in chickens have mutated to highly pathogenic viruses that have caused ...

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