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Vahey MD, Fletcher DA. Low-Fidelity Assembly of Influenza A Virus Promotes Escape from Host Cells. Cell. 2018 Nov 27.  Abstract  
submitted by kickingbird at Dec, 9, 2018 from Cell. 2018 Nov 27 (via https://www.ncbi.nlm.nih.gov/pubmed/30503209)
Influenza viruses inhabit a wide range of host environments using a limited repertoire of protein components. Unlike viruses with stereotyped shapes, influenza produces virions with significant morphological ...

Zhang X, et al. Tissue tropisms opt for transmissible reassortants during avian and swine influenza A virus co-infection in swine. PLoS Pathog. 2018 Dec 3;14(12).  Abstract  
submitted by kickingbird at Dec, 9, 2018 from PLoS Pathog. 2018 Dec 3;14(12) (via https://www.ncbi.nlm.nih.gov/pubmed/30507946)
Genetic reassortment between influenza A viruses (IAVs) facilitate emergence of pandemic strains, and swine are proposed as a "mixing vessel" for generating reassortants of avian and mammalian IAVs that ...

Tan KS, et al. Comparative Transcriptomic and Metagenomic Analyses of Influenza Virus-Infected Nasal Epithelial Cells From Multiple Individuals Reveal Specific Nasal-Initiated Signatures. Front Microbiol. 2018 Nov 14;9:2685.  Abstract  
submitted by kickingbird at Dec, 6, 2018 from Front Microbiol. 2018 Nov 14;9:2685 (via https://www.ncbi.nlm.nih.gov/pubmed/30487780)
In vitro and in vivo research based on cell lines and animals are likely to be insufficient in elucidating authentic biological and physiological phenomena mimicking human systems, especially for generating ...

Long JS, Mistry B, Haslam SM, Barclay WS. Host and viral determinants of influenza A virus species specificity. Nat Rev Microbiol. 2018 Nov 28.  Abstract  
submitted by kickingbird at Dec, 6, 2018 from Nat Rev Microbiol. 2018 Nov 28 (via https://www.nature.com/articles/s41579-018-0115-z)
Influenza A viruses cause pandemics when they cross between species and an antigenically novel virus acquires the ability to infect and transmit between these new hosts. The timing of pandemics is currently ...

?van?arová P, Betáková T. Conserved methionine 165 of matrix protein contributes to the nuclear import and is essential for influenza A virus replication. Virol J. 2018 Dec 3;15(1):187.  Abstract  
submitted by kickingbird at Dec, 6, 2018 from Virol J. 2018 Dec 3;15(1):187 (via https://www.ncbi.nlm.nih.gov/pubmed/30509291)
BACKGROUND: The influenza matrix protein (M1) layer under the viral membrane plays multiple roles in virus assembly and infection. N-domain and C-domain are connected by a loop region, which consists of ...

Ampomah PB, et al. Annexins in Influenza Virus Replication and Pathogenesis. Front Pharmacol. 2018 Nov 15;9:1282.  Abstract  
submitted by kickingbird at Dec, 6, 2018 from Front Pharmacol. 2018 Nov 15;9:1282 (via https://www.ncbi.nlm.nih.gov/pubmed/30498445)
Influenza A viruses (IAVs) are important human respiratory pathogens which cause seasonal or periodic endemic infections. IAV can result in severe or fatal clinical complications including pneumonia and ...

Zhou J, et al. Identification and characterization of GLDC as host susceptibility gene to severe influenza. EMBO Mol Med. 2018 Nov 28..  Abstract  
submitted by kickingbird at Dec, 4, 2018 from EMBO Mol Med. 2018 Nov 28. (via https://www.ncbi.nlm.nih.gov/pubmed/30498026)
Glycine decarboxylase (GLDC) was prioritized as a candidate susceptibility gene to severe influenza in humans. The higher expression of GLDC derived from genetic variations may confer a higher risk to ...

Boyle CC, et al. Inflammation and dimensions of reward processing following exposure to the influenza vaccine. Psychoneuroendocrinology. 2018 Nov 20;102:16-23..  Abstract  
submitted by kickingbird at Dec, 4, 2018 from Psychoneuroendocrinology. 2018 Nov 20;102:16-23. (via https://www.ncbi.nlm.nih.gov/pubmed/30496908)
BACKGROUND: Alterations in reward processing are a central feature of depression and may be influenced by inflammation. Indeed, inflammation is associated with deficits in reward-related processes in animal ...

Chaimayo C, et al. Specificity and functional interplay between influenza virus PA-X and NS1 shutoff activity. PLoS Pathog. 2018 Nov 29;14(11):e1007465.  Abstract  
submitted by kickingbird at Dec, 4, 2018 from PLoS Pathog. 2018 Nov 29;14(11):e1007465 (via https://www.ncbi.nlm.nih.gov/pubmed/30496325)
Influenza A viruses modulate host antiviral responses to promote viral growth and pathogenicity. Through viral PA-X and NS1 proteins, the virus is capable of suppressing host protein synthesis, termed ...

Oladipo EK, Oloke JK, Adeniji JA. Intravenous pathogenicity of influenza virus A/H5N1/2014 isolated from pig in Ogbomoso, Nigeria. Open Vet J. 2018;8(3):347-350..  Abstract  
submitted by kickingbird at Dec, 4, 2018 from Open Vet J. 2018;8(3):347-350. (via https://www.ncbi.nlm.nih.gov/pubmed/30483460)
Understanding the pathogenicity of avian influenza viruses in poultry is an important scientific and public health challenge because of antigenic shift/drift and a source of novel, potentially human-pathogenic ...

Imai K, et al. Whole Genome Sequencing of Influenza A and B Viruses With the MinION Sequencer in the Clinical Setting: A Pilot Study. Front Microbiol. 2018 Nov 13;9:2748..  Abstract  
submitted by kickingbird at Dec, 4, 2018 from Front Microbiol. 2018 Nov 13;9:2748. (via https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6243006/)
Introduction: Whole genome sequencing (WGS) of influenza viruses is important for preparing vaccines and coping with newly emerging viruses. However, WGS is difficult to perform using conventional next-generation ...

Rimondi A, et al. Evidence of a fixed internal gene constellation in influenza A viruses isolated from wild birds in Argentina (2006-2016). Emerg Microbes Infect. 2018 Nov 28;7(1):194.  Abstract  
submitted by kickingbird at Dec, 4, 2018 from Emerg Microbes Infect. 2018 Nov 28;7(1):194 (via https://www.ncbi.nlm.nih.gov/pubmed/30482896)
Wild aquatic birds are the major reservoir of influenza A virus. Cloacal swabs and feces samples (n?=?6595) were collected from 62 bird species in Argentina from 2006 to 2016 and screened for influenza ...

Golovko AO, et al. Aggregation of Influenza A Virus Nuclear Export Protein. Biochemistry (Mosc). 2018 Nov;83.  Abstract  
submitted by kickingbird at Dec, 4, 2018 from Biochemistry (Mosc). 2018 Nov;83 (via https://www.ncbi.nlm.nih.gov/pubmed/30482152)
Influenza A virus nuclear export protein (NEP) plays an important role in the viral life cycle. Recombinant NEP proteins containing (His)6-tag at either N- or C-terminus were obtained by heterologous expression ...

Ozawa M, et al. Phylogenetic variations of highly pathogenic H5N6 avian influenza viruses isolated from wild birds in the Izumi plain, Japan during the 2016/17 winter season. Transbound Emerg Dis. 2018 Nov 30.  Abstract  
submitted by kickingbird at Dec, 4, 2018 from Transbound Emerg Dis. 2018 Nov 30 (via https://www.ncbi.nlm.nih.gov/pubmed/30499632)
During the 2016/2017 winter season, we isolated 33 highly pathogenic avian influenza viruses (HPAIVs) of H5N6 subtype and three low pathogenic avian influenza viruses (LPAIVs) from debilitated or dead ...

Huang KA, et al. Structure-function analysis of neutralizing antibodies to H7N9 influenza from naturally infected humans. Nat Microbiol. 2018 Nov 26..  Abstract  
submitted by kickingbird at Nov, 30, 2018 from Nat Microbiol. 2018 Nov 26. (via https://www.ncbi.nlm.nih.gov/pubmed/30478290)
Little is known about the specificities and neutralization breadth of the H7-reactive antibody repertoire induced by natural H7N9 infection in humans. We have isolated and characterized 73 H7-reactive ...

Yan Z, et al. Evolutionary changes of the novel Influenza D virus hemagglutinin-esterase fusion gene revealed by the codon usage pattern. Virulence. 2018 Nov 26.  Abstract  
submitted by kickingbird at Nov, 27, 2018 from Virulence. 2018 Nov 26 (via https://www.ncbi.nlm.nih.gov/pubmed/30475085)
The codon usage pattern can reveal the adaptive changes that allow virus survival and fitness adaptation to their particular host, as well as the external environment. Although still considered a novel ...

Zhang J, et al. Molecular evolutionary and antigenic characteristics of newly isolated H9N2 avian influenza viruses in Guangdong province, China. Arch Virol. 2018 Nov 24..  Abstract  
submitted by kickingbird at Nov, 27, 2018 from Arch Virol. 2018 Nov 24. (via https://www.ncbi.nlm.nih.gov/pubmed/30474753)
Four new H9N2 avian influenza viruses (AIVs) were isolated from domestic birds in Guangdong between December 2015 and April 2016. Nucleotide sequence comparisons indicated that most of the internal genes ...

Abolnik C, Stutchbury S, Hartman MJ. Experimental infection of racing pigeons (Columba livia domestica) with highly pathogenic Clade 2.3.4.4 sub-group B H5N8 avian influenza virus. Vet Microbiol. 2018 Dec;227:127-132..  Abstract  
submitted by kickingbird at Nov, 27, 2018 from Vet Microbiol. 2018 Dec;227:127-132. (via https://www.ncbi.nlm.nih.gov/pubmed/30473343)
Reported mass mortalities in wild pigeons and doves during the 2017/2018 Clade 2.3.4.4 HPAI H5N8 outbreaks in South Africa necessitated an investigation of healthy racing pigeons for their susceptibility ...

Wang K, et al. Serological surveillance of avian influenza virus and canine distemper virus in captive Siberian Tigers in Northeastern China. Pol J Vet Sci. 2018 Sep;21(3):491-495..  Abstract  
submitted by kickingbird at Nov, 26, 2018 from Pol J Vet Sci. 2018 Sep;21(3):491-495. (via https://www.ncbi.nlm.nih.gov/pubmed/30468333)
In order to understand infection of avian influenza A virus (AIV) and canine distemper virus (CDV) in the Siberian Tiger in Northeast China, 75 Siberian Tiger serum samples from three cap- tive facilities ...

Lin HT, Chen CC, Liu PY, Wu HL, Wu TH, et al. Grail attenuates influenza A virus infection and pathogenesis by inhibiting viral nucleoprotein. Sci Rep. 2018 Nov 22;8(1):17242.  Abstract  
submitted by kickingbird at Nov, 26, 2018 from Sci Rep. 2018 Nov 22;8(1):17242 (via https://www.ncbi.nlm.nih.gov/pubmed/30467324)
Grail is a well-characterized mediator of metabolic disease, tumour progression, and immune response. However, its role in influenza A virus (IAV) infection remains poorly understood. In this study, we ...

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