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2024-3-29 18:36:16
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Jegede A, Fu Q, Lin M, Kumar A, Guan J. Aerosol exposure enhanced infection of low pathogenic avian influenza viruses in chickens. Transbound Emerg Dis. 2018 Oct 11..  Abstract  
submitted by kickingbird at Oct, 15, 2018 from Transbound Emerg Dis. 2018 Oct 11. (via https://www.ncbi.nlm.nih.gov/pubmed/30307712)
To assess the impact of different routes of inoculation on experimental infection of avian influenza (AI) viruses in chickens, this study compared virus replication and cytokine gene expression in respiratory ...

Tome-Amat J, et al. Influenza A virus utilizes low affinity, high avidity interactions with the nuclear import machinery to ensure infection and immune evasion. J Virol. 2018 Oct 10.  Abstract  
submitted by kickingbird at Oct, 15, 2018 from J Virol. 2018 Oct 10 (via https://www.ncbi.nlm.nih.gov/pubmed/30305352)
The incoming influenza A virus (IAV) genome must pass through two distinct barriers in order to establish infection in the cell- the plasma membrane and the nuclear membrane. A precise understanding of ...

Shi B, et al. Identifying key bird species and geographical hotspots of avian influenza A (H7N9) virus in China. Infect Dis Poverty. 2018 Oct 11;7(1):97..  Abstract  
submitted by kickingbird at Oct, 15, 2018 from Infect Dis Poverty. 2018 Oct 11;7(1):97. (via https://www.ncbi.nlm.nih.gov/pubmed/30305184)
BACKGROUND: In China since the first human infection of avian influenza A (H7N9) virus was identified in 2013, it has caused serious public health concerns due to its wide spread and high mortality rate. ...

Wang L, et al. Inhibition of autophagy and chemokine induction by sphingosine 1-phosphate receptor 1 through NF-κB signaling in human pulmonary endothelial cells infected with influenza A viruses. PLoS One. 2018 Oct 10;13(10):e0205344..  Abstract  
submitted by kickingbird at Oct, 15, 2018 from PLoS One. 2018 Oct 10;13(10):e0205344. (via https://www.ncbi.nlm.nih.gov/pubmed/30304001)
Endothelial cells have been considered the central regulators of cytokine storm in the respiratory system during influenza virus infection. Studies have found that elevated autophagy could be an essential ...

Nooruzzaman M, Haque ME, Chowdhury EH, Islam MR. Pathology of Clade 2.3.2.1 Avian Influenza Virus (H5N1) Infection in Quails and Ducks in Bangladesh. Avian Pathol. 2018 Oct 10:1-21.  Abstract  
submitted by kickingbird at Oct, 15, 2018 from Avian Pathol. 2018 Oct 10:1-21 (via https://www.ncbi.nlm.nih.gov/pubmed/30303027)
We performed pathological and molecular virological investigation of three outbreaks of highly pathogenic avian influenza (HPAI) in a quail farm and two duck farms of Mymensingh and Netrokona districts ...

Wu H, et al. Molecular characterization of H10 subtype avian influenza viruses isolated from poultry in Eastern China. Arch Virol. 2018 Oct 9.  Abstract  
submitted by kickingbird at Oct, 15, 2018 from Arch Virol. 2018 Oct 9 (via https://www.ncbi.nlm.nih.gov/pubmed/30302582)
In recent years, avian-origin H10 influenza viruses have proved capable of infecting human beings, and they pose a potential public health threat. Seven H10 avian influenza viruses (AIVs), H10N3 (n?=?2), ...

Akand EH, Downard KM. Ancestral and Compensatory Mutations that Promote Antiviral Resistance in Influenza N1 Neuraminidase Revealed by a Phylonumerics Approach. J Mol Evol. 2018 Oct 9..  Abstract  
submitted by kickingbird at Oct, 15, 2018 from J Mol Evol. 2018 Oct 9. (via https://www.ncbi.nlm.nih.gov/pubmed/30302501)
Implementation of a new phylonumerics approach to construct a mass tree representing over 6000 H1N1 human influenza strains has enabled ancestral and compensatory descendant mutations to be identified ...

Vom Steeg LG, Klein SL. Sex and sex steroids impact influenza pathogenesis across the life course. Semin Immunopathol. 2018 Oct 8.  Abstract  
submitted by kickingbird at Oct, 15, 2018 from Semin Immunopathol. 2018 Oct 8 (via https://www.ncbi.nlm.nih.gov/pubmed/30298431)
Males and females differ in the outcome of influenza A virus (IAV) infections, which depends significantly on age. During a typical seasonal influenza epidemic, young children (

Beigel JH. Polyclonal and monoclonal antibodies for the treatment of influenza. Curr Opin Infect Dis. 2018 Oct 5..  Abstract  
submitted by kickingbird at Oct, 15, 2018 from Curr Opin Infect Dis. 2018 Oct 5. (via https://www.ncbi.nlm.nih.gov/pubmed/30299360)
PURPOSE OF REVIEW: This review summarizes past and ongoing efforts for using polyclonal and monoclonal antibodies for the treatment of influenza, and is focused on products that have entered clinical trials.RECENT ...

Vanderbeke L, et al. Invasive pulmonary aspergillosis complicating severe influenza: epidemiology, diagnosis and treatment. Curr Opin Infect Dis. 2018 Oct 5.  Abstract  
submitted by kickingbird at Oct, 15, 2018 from Curr Opin Infect Dis. 2018 Oct 5 (via https://www.ncbi.nlm.nih.gov/pubmed/30299367)
PURPOSE OF REVIEW: Bacterial superinfection of critically ill influenza patients is well-known, but in recent years, more and more reports describe invasive aspergillosis as a frequent complication as ...

Li J, et al.. Continued reassortment of avian H6 influenza viruses from Southern China, 2014~2016. Transbound Emerg Dis. 2018 Oct 9..  Abstract  
submitted by kickingbird at Oct, 15, 2018 from Transbound Emerg Dis. 2018 Oct 9. (via https://www.ncbi.nlm.nih.gov/pubmed/30300968)
H6 subtype avian influenza virus (AIV) was prevalent in poultry and could sporadically infect humans. Here, a total of 196 novel H6 AIVs isolated from poultry in eight provinces of China from 2014 to 2016 ...

Khurana S, et al. AS03-adjuvanted H5N1 vaccine promotes antibody diversity and affinity maturation, NAI titers, cross-clade H5N1 neutralization, but not H1N1 cross-subtype neutralization. NPJ Vaccines. 2018 Oct 1;3:40..  Abstract  
submitted by kickingbird at Oct, 15, 2018 from NPJ Vaccines. 2018 Oct 1;3:40. (via https://www.ncbi.nlm.nih.gov/pubmed/30302282)
Immune responses to inactivated vaccines against avian influenza are poor due in part to lack of immune memory. Adjuvants significantly increased virus neutralizing titers. We performed comprehensive analyses ...

Li R, et al.. Tree shrew as a new animal model to study the pathogenesis of avian influenza (H9N2) virus infection. Emerg Microbes Infect. 2018 Oct 10;7(1):166..  Abstract  
submitted by kickingbird at Oct, 15, 2018 from Emerg Microbes Infect. 2018 Oct 10;7(1):166. (via https://www.ncbi.nlm.nih.gov/pubmed/30301950)
Outbreaks of avian influenza virus continue to pose threats to human health. Animal models such as the mouse, ferret, and macaque are used to understand the pathogenesis of avian influenza virus infection ...

Van Hemert C, et., al. Survey of Arctic Alaskan Wildlife For Influenza A Antibodies: Limited Evidence For Exposure of Mammals. J Wildl Dis. 2018 Oct 5..  Abstract  
submitted by kickingbird at Oct, 11, 2018 from J Wildl Dis. 2018 Oct 5. (via https://www.ncbi.nlm.nih.gov/pubmed/30289331)
Influenza A viruses (IAVs) are maintained in wild waterbirds and have the potential to infect a broad range of species, including wild mammals. The Arctic Coastal Plain of Alaska supports a diverse suite ...

Hagan RS, Torres-Castillo J, Doerschuk CM. Myeloid TBK1 Signaling Contributes to the Immune Response to Influenza. Am J Respir Cell Mol Biol. 2018 Oct 5..  Abstract  
submitted by kickingbird at Oct, 11, 2018 from Am J Respir Cell Mol Biol. 2018 Oct 5. (via https://www.ncbi.nlm.nih.gov/pubmed/30290124)
Macrophages provide key elements of the host response to influenza A virus (IAV) infection, including expression of type I interferon (IFN) and inflammatory cytokines and chemokines. TANK-binding kinase ...

Lee MS, Jang EY, Cho J, Kim K, Lee CH. Development and comparison of two H5N8 influenza A vaccine candidate strains. Arch Virol. 2018 Oct 5..  Abstract  
submitted by kickingbird at Oct, 11, 2018 from Arch Virol. 2018 Oct 5. (via https://www.ncbi.nlm.nih.gov/pubmed/30291503)
Avian influenza viruses circulating in birds have caused outbreaks of infection in poultry and humans, thereby threatening public health. Recently, a highly pathogenic avian influenza (HPAI) virus (H5N8) ...

Yu Z, Gao Y, He H, Zhao Y, Yuan X, Cheng K. Isolation and genetic characterization of H13N8 low pathogenic avian influenza virus from migratory birds in eastern China. Transbound Emerg Dis. 2018 Oct 6.  Abstract  
submitted by kickingbird at Oct, 11, 2018 from Transbound Emerg Dis. 2018 Oct 6 (via https://www.ncbi.nlm.nih.gov/pubmed/30291732)
Low pathogenic avian influenza virus (LPAIV) is an important zoonotic pathogen. Migratory birds are the natural reservoir for all 16 haemagglutinin (HA) and 9 neuraminidase (NA) subtypes of LPAIV. Surveillance ...

Yamayoshi S, Yasuhara A, Ito M, Uraki R, Kawaoka Y. Differences in the ease with which mutant viruses escape from human monoclonal antibodies against the HA stem of influenza A virus. J Clin Virol. 2018 Sep 26;108:105-111.  Abstract  
submitted by kickingbird at Oct, 11, 2018 from J Clin Virol. 2018 Sep 26;108:105-111 (via https://www.ncbi.nlm.nih.gov/pubmed/30292135)
BACKGROUND: Broadly protective human monoclonal antibodies that recognize the conserved epitopes in the HA of influenza A virus are being developed as therapeutic agents. Emergence of resistant viruses ...

Marchenko V, etc.,al. Isolation and characterization of H5Nx highly pathogenic avian influenza viruses of clade 2.3.4.4 in Russia. Virology. 2018 Oct 5;525:216-223.  Abstract  
submitted by kickingbird at Oct, 10, 2018 from Virology. 2018 Oct 5;525:216-223 (via https://www.ncbi.nlm.nih.gov/pubmed/30296682)
In 2016-2017, several subtypes of the highly pathogenic avian influenza (HPAI) virus were isolated on the territory of Russia. In the autumn of 2016, during the avian influenza virus surveillance in the ...

Haag R, et., al. Exploring rigid and flexible core trivalent sialosides for influenza virus inhibition. Chemistry. 2018 Oct 8..  Abstract  
submitted by kickingbird at Oct, 10, 2018 from Chemistry. 2018 Oct 8. (via https://www.ncbi.nlm.nih.gov/pubmed/30295350)
We describe the chemical synthesis and binding analysis of functionalizable rigid and flexible core trivalent sialosides bearing oligoethylene glycol (OEG) spacers interacting with spike proteins of influenza ...

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