Zhao L,Zhang X,Wu Z,Huang K,Sun X,Chen H, Jin M. The Downregulation of MicroRNA hsa-miR-340-5p in IAV-Infected A549 Cells Suppresses Viral Replication by Targeting RIG-I and OAS2. Mol Ther Nucleic Acids. 2019 Jan 10;14:509-519.. Abstract
submitted by kickingbird at Feb, 14, 2019 from Mol Ther Nucleic Acids. 2019 Jan 10;14:509-519. (via https://www.ncbi.nlm.nih.gov/pubmed/30753994)
The influenza A virus poses serious public health challenges worldwide. Strikingly, small noncoding microRNAs (miRNAs) that modulate gene expression are closely involved in antiviral responses, although ... Wan YH, et al. Genetic characteristic of hemagglutinin of avian influenza A (H7N9) virus in Guizhou Province in 2017. Zhonghua Yu Fang Yi Xue Za Zhi. 2019 Feb 6;53(2):2. Abstract
submitted by kickingbird at Feb, 14, 2019 from Zhonghua Yu Fang Yi Xue Za Zhi. 2019 Feb 6;53(2):2 (via https://www.ncbi.nlm.nih.gov/pubmed/30744302)
The number of H7N9 bird flu cases was high and the situation was grim in guizhou province in 2017. To understand the molecular characteristics of the hemagglutinin gene (HA) and the risk of human infection ... Bosco-Lauth AM, et al. Shedding of clade 2.3.4.4 H5N8 and H5N2 highly pathogenic avian influenza viruses in peridomestic wild birds in the U.S.. Transbound Emerg Dis. 2019 Feb 10. Abstract
submitted by kickingbird at Feb, 13, 2019 from Transbound Emerg Dis. 2019 Feb 10 (via https://www.ncbi.nlm.nih.gov/pubmed/30740920)
European starlings (Sturnus vulgaris), house sparrows (Passer domesticus) and rock pigeons (Columba livia) are all wild birds commonly found in large numbers in and around human dwellings and domestic ... Wang R, et al. Influenza M2 protein regulates MAVS-mediated signaling pathway through interacting with MAVS and increasing ROS production. Autophagy. 2019 Feb 11.. Abstract
submitted by kickingbird at Feb, 13, 2019 from Autophagy. 2019 Feb 11. (via https://www.ncbi.nlm.nih.gov/pubmed/30741586)
Influenza A virus can evade host innate immune response that is involved in several viral proteins with complicated mechanisms. To date, how influenza A M2 protein modulates the host innate immunity remains ... Kanekiyo M, et al. Mosaic nanoparticle display of diverse influenza virus hemagglutinins elicits broad B cell responses. Nat Immunol. 2019 Feb 11. Abstract
submitted by kickingbird at Feb, 13, 2019 from Nat Immunol. 2019 Feb 11 (via https://www.ncbi.nlm.nih.gov/pubmed/30742080)
The present vaccine against influenza virus has the inevitable risk of antigenic discordance between the vaccine and the circulating strains, which diminishes vaccine efficacy. This necessitates new approaches ... Vuichard-Gysin D, et al. Development and validation of clinical prediction models to distinguish influenza from other viruses causing acute respiratory infections in children and adults. PLoS One. 2019 Feb 11;14(2):e0212050. Abstract
submitted by kickingbird at Feb, 13, 2019 from PLoS One. 2019 Feb 11;14(2):e0212050 (via https://www.ncbi.nlm.nih.gov/pubmed/30742654)
Predictive models have been developed for influenza but have seldom been validated. Typically they have focused on patients meeting a definition of infection that includes fever. Less is known about how ... Mohl G, et al. Novel influenza inhibitors designed to target PB1 interactions with host importin RanBP5. Antiviral Res. 2019 Feb 8.. Abstract
submitted by kickingbird at Feb, 13, 2019 from Antiviral Res. 2019 Feb 8. (via https://www.ncbi.nlm.nih.gov/pubmed/30742842)
In search of novel targets for influenza inhibitors, a site on PB1 was selected for its high conservation and probable interaction with a host protein, RanBP5, that is key to nuclear import of PB1, where ... Kwa?nik M, et al. Genetic Analysis of the M Gene of Equine Influenza Virus Strains Isolated in Poland, in the Context of the Asian-like Group Formation. J Vet Res. 2018 Dec 31;62(4):405-412. Abstract
submitted by kickingbird at Feb, 11, 2019 from J Vet Res. 2018 Dec 31;62(4):405-412 (via https://www.ncbi.nlm.nih.gov/pubmed/30729195)
Introduction: Traditionally, evolutionary analysis of equine influenza virus (EIV) is based on the HA gene. However, the specificity of the influenza virus enables the classification of viral strains into ... Jin M, Jang Y, Seo T, Seo SH. Inactivated H5 Antigens of H5N8 Protect Chickens from Lethal Infections by the Highly Pathogenic H5N8 and H5N6 Avian Influenza Viruses. J Vet Res. 2018 Dec 31;62(4):413-420. Abstract
submitted by kickingbird at Feb, 11, 2019 from J Vet Res. 2018 Dec 31;62(4):413-420 (via https://www.ncbi.nlm.nih.gov/pubmed/30729196)
Introduction: Highly pathogenic Asian H5-subtype avian influenza viruses have been found in poultry and wild birds worldwide since they were first detected in southern China in 1996. Extensive control ... Fallah Mehrabadi MH, et al. Full-genome characterization and genetic analysis of a H9N2 virus in commercial broilers in Iran, 2017. Trop Anim Health Prod. 2019 Feb 7. Abstract
submitted by kickingbird at Feb, 11, 2019 from Trop Anim Health Prod. 2019 Feb 7 (via https://www.ncbi.nlm.nih.gov/pubmed/30729386)
Since 1998, Iran's poultry industry has faced several outbreaks of low pathogenic avian influenza H9N2. Tissue samples were collected from a broiler flock with respiratory symptoms in autumn 2017. After ... Nelson MI, Souza C, et al. Human-Origin Influenza A(H3N2) Reassortant Viruses in Swine, Southeast Mexico. Emerg Infect Dis. 2019 Apr 17;25(4).. Abstract
submitted by kickingbird at Feb, 11, 2019 from Emerg Infect Dis. 2019 Apr 17;25(4). (via https://www.ncbi.nlm.nih.gov/pubmed/30730827)
The genetic diversity of influenza A viruses circulating in swine in Mexico complicates control efforts in animals and presents a threat to humans, as shown by influenza A(H1N1)pdm09 virus. To describe ... Zhu H, et al. Absence of adaptive evolution is the main barrier against influenza emergence in horses in Asia despite frequent virus interspecies transmission from wild birds. PLoS Pathog. 2019 Feb 7;15(2):e1007531.. Abstract
submitted by kickingbird at Feb, 11, 2019 from PLoS Pathog. 2019 Feb 7;15(2):e1007531. (via https://www.ncbi.nlm.nih.gov/pubmed/30731004)
Virus ecology and evolution play a central role in disease emergence. However, their relative roles will vary depending on the viruses and ecosystems involved. We combined field studies, phylogenetics ... Nagy A, Ji?inec T, Ji?incová H, ?erníková L, et al. In silico re-assessment of a diagnostic RT-qPCR assay for universal detection of Influenza A viruses. Sci Rep. 2019 Feb 7;9(1):1630.. Abstract
submitted by kickingbird at Feb, 11, 2019 from Sci Rep. 2019 Feb 7;9(1):1630. (via https://www.ncbi.nlm.nih.gov/pubmed/30733500)
The ongoing evolution of microbial pathogens represents a significant issue in diagnostic PCR/qPCR. Many assays are burdened with false negativity due to mispriming and/or probe-binding failures. Therefore, ... Feng H, Yamashita M, da Silva Lopes TJ, et al. Injectable Excipients as Novel Influenza Vaccine Adjuvants. Front Microbiol. 2019 Jan 24;10:19. Abstract
submitted by kickingbird at Feb, 11, 2019 from Front Microbiol. 2019 Jan 24;10:19 (via https://www.ncbi.nlm.nih.gov/pubmed/30733711)
Influenza outbreaks can be either seasonal or pandemic. Vaccination is an effective strategy to control influenza; however, the efficacy of the currently available inactivated influenza virus vaccines ... Mosaad Z, et al. In silico thermodynamic stability of mammalian adaptation and virulence determinants in polymerase complex proteins of H9N2 virus. J Genet Eng Biotechnol. 2018 Dec;16(2):757-767. Abstract
submitted by kickingbird at Feb, 11, 2019 from J Genet Eng Biotechnol. 2018 Dec;16(2):757-767 (via https://www.ncbi.nlm.nih.gov/pubmed/30733797)
The polymerase complex proteins (PB2, PB1, and PA) are responsible primarily for the replication of avian influenza virus and play an important role in virus virulence, mammalian adaptation, and interspecies ... Chamberlain N, et al. Lung epithelial protein disulfide isomerase A3 (PDIA3) plays an important role in influenza infection, inflammation, and airway mechanics. Redox Biol. 2019 Jan 29;22:101129. Abstract
submitted by kickingbird at Feb, 11, 2019 from Redox Biol. 2019 Jan 29;22:101129 (via https://www.ncbi.nlm.nih.gov/pubmed/30735910)
Protein disulfide isomerases (PDI) are a family of redox chaperones that catalyze formation or isomerization of disulfide bonds in proteins. Previous studies have shown that one member, PDIA3, interacts ... Wang P, et al. Structural and functional definition of a vulnerable site on the hemagglutinin of highly pathogenic avian influenza A virus H5N1. J Biol Chem. 2019 Feb 8.. Abstract
submitted by kickingbird at Feb, 11, 2019 from J Biol Chem. 2019 Feb 8. (via https://www.ncbi.nlm.nih.gov/pubmed/30737282)
Most neutralizing antibodies against highly pathogenic avian influenza A virus H5N1 recognize the receptor-binding site (RBS) on the globular head domain and the stem of H5N1 hemagglutinin (HA). Through ... Moriyama M, Ichinohe T. High ambient temperature dampens adaptive immune responses to influenza A virus infection. Proc Natl Acad Sci U S A. 2019 Feb 4.. Abstract
submitted by kickingbird at Feb, 8, 2019 from Proc Natl Acad Sci U S A. 2019 Feb 4. (via https://www.ncbi.nlm.nih.gov/pubmed/30718396)
Although climate change may expand the geographical distribution of several vector-borne diseases, the effects of environmental temperature in host defense to viral infection in vivo are unknown. Here, ... Sato M, et al. Generation of bat-derived influenza viruses and their reassortants. Sci Rep. 2019 Feb 4;9(1):1158.. Abstract
submitted by kickingbird at Feb, 8, 2019 from Sci Rep. 2019 Feb 4;9(1):1158. (via https://www.ncbi.nlm.nih.gov/pubmed/30718752)
Two novel influenza A virus-like genomes were detected in fruit bats in Central and South America. However, the biological properties of these bat-derived influenza viruses (BatIVs) are still largely unknown ... Zhao Z, et al. A Novel Reassortant Avian H7N6 Influenza Virus Is Transmissible in Guinea Pigs via Respiratory Droplets. Front Microbiol. 2019 Jan 22. Abstract
submitted by kickingbird at Feb, 8, 2019 from Front Microbiol. 2019 Jan 22 (via https://www.ncbi.nlm.nih.gov/pubmed/30723462)
Since 2013, H7N9 and H5N6 avian influenza viruses (AIVs) have caused sporadic human infections and deaths and continued to circulate in the poultry industry. Since 2014, H7N6 viruses which might be reassortants ... 5328 items, 20/Page, Page[121/267][|<<] [|<] [121] [122] [123] [124] [125] [126] [127] [128] [129] [130] [>|] [>>|] |
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