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2024-4-29 6:11:34
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Amaro RE, et al. A Computational Assay that Explores the Hemagglutinin/Neuraminidase Functional Balance Reveals the Neuraminidase Secondary Site as a Novel Anti-Influenza Target. ACS Cent Sci. 2018 Nov 28;4(11):1570-1577.  Abstract  
submitted by kickingbird at Dec, 20, 2018 from ACS Cent Sci. 2018 Nov 28;4(11):1570-1577 (via https://www.ncbi.nlm.nih.gov/pubmed/30555910)
Studies of pathogen-host specificity, virulence, and transmissibility are critical for basic research as well as for assessing the pandemic potential of emerging infectious diseases. This is especially ...

Han L, et al. The evolution and molecular characteristics of H9N2 avian influenza viruses in Jiangxi of China. J Med Virol. 2018 Dec 17.  Abstract  
submitted by kickingbird at Dec, 20, 2018 from J Med Virol. 2018 Dec 17 (via https://www.ncbi.nlm.nih.gov/pubmed/30560545)
To understand the evolution and molecular characteristics of Jiangxi H9N2 viruses, we isolated 17 viruses in 2011 and analyzed their characteristics. Phylogenetic analyses revealed that their hemagglutinin ...

Nogales A, Martinez-Sobrido L, Topham DJ, et al. Modulation of Innate Immune Responses by the Influenza A NS1 and PA-X Proteins. Viruses. 2018 Dec 12;10(12)..  Abstract  
submitted by kickingbird at Dec, 18, 2018 from Viruses. 2018 Dec 12;10(12). (via https://www.ncbi.nlm.nih.gov/pubmed/30545063)
Influenza A viruses (IAV) can infect a broad range of animal hosts, including humans. In humans, IAV causes seasonal annual epidemics and occasional pandemics, representing a serious public health and ...

York IA, Stevens J, Alymova IV. Influenza Virus N-linked Glycosylation and Innate Immunity. Biosci Rep. 2018 Dec 14.  Abstract  
submitted by kickingbird at Dec, 18, 2018 from Biosci Rep. 2018 Dec 14 (via https://www.ncbi.nlm.nih.gov/pubmed/30552137)
Influenza viruses cause seasonal epidemics and sporadic pandemics in humans. The virus's ability to change its antigenic nature through mutation and recombination, and the difficulty in developing highly ...

Tangwangvivat R, et al. Evidence of pandemic H1N1 influenza exposure in dogs and cats, Thailand: A serological survey. Zoonoses Public Health. 2018 Dec 14.  Abstract  
submitted by kickingbird at Dec, 18, 2018 from Zoonoses Public Health. 2018 Dec 14 (via https://www.ncbi.nlm.nih.gov/pubmed/30552750)
Influenza A virus causes respiratory disease in both humans and animals. In this study, a survey of influenza A antibodies in domestic dogs and cats was conducted in 47 animal shelters in 19 provinces ...

Britton AP, et al. Probable reverse zoonosis of influenza A(H1N1)pdm 09 in a striped skunk (Mephitis mephitis). Zoonoses Public Health. 2018 Dec 14.  Abstract  
submitted by kickingbird at Dec, 18, 2018 from Zoonoses Public Health. 2018 Dec 14 (via https://www.ncbi.nlm.nih.gov/pubmed/30552753)
Striped skunks (skunks) are susceptible to respiratory infection by influenza A viruses (IAV). As they are common synanthropes, maintenance of IAV in skunks could provide a source of infection for humans. ...

Tanikawa T, et al. Pathogenicity of two novel human-origin H7N9 highly pathogenic avian influenza viruses in chickens and ducks. Arch Virol. 2018 Dec 11..  Abstract  
submitted by kickingbird at Dec, 14, 2018 from Arch Virol. 2018 Dec 11. (via https://www.ncbi.nlm.nih.gov/pubmed/30539262)
Human infection by low-pathogenic avian influenza viruses of the H7N9 subtype was first reported in March 2013 in China. Subsequently, these viruses caused five outbreaks through September 2017. In the ...

Lamichhane PP, Puthavathana P. PR8 virus harbouring H5N1 NS gene contributed for THP-1 cell tropism. Virusdisease. 2018 Dec;29(4):548-552..  Abstract  
submitted by kickingbird at Dec, 14, 2018 from Virusdisease. 2018 Dec;29(4):548-552. (via https://www.ncbi.nlm.nih.gov/pubmed/30539061)
Innate immune cells are key player in immune response to influenza virus infection. Influenza infected monocytes exacerbate the disease pathology. However, monocytes differ in susceptibilities to influenza ...

Zhang K, et al. Structural-functional interactions of NS1-BP protein with the splicing and mRNA export machineries for viral and host gene expression. Proc Natl Acad Sci U S A. 2018 Dec 11.  Abstract  
submitted by kickingbird at Dec, 14, 2018 from Proc Natl Acad Sci U S A. 2018 Dec 11 (via https://www.ncbi.nlm.nih.gov/pubmed/30538201)
The influenza virulence factor NS1 protein interacts with the cellular NS1-BP protein to promote splicing and nuclear export of the viral M mRNAs. The viral M1 mRNA encodes the M1 matrix protein and is ...

Fike AJ, Kumova OK, Tardif VJ, Carey AJ. Neonatal influenza-specific effector CTLs retain elevated CD31 levels at the site of infection and have decreased IFN-γ production. J Leukoc Biol. 2018 Dec 11..  Abstract  
submitted by kickingbird at Dec, 14, 2018 from J Leukoc Biol. 2018 Dec 11. (via https://www.ncbi.nlm.nih.gov/pubmed/30536476)
The underlying mechanisms that regulate neonatal immune suppression are poorly characterized. CD31 (PECAM1) is highly expressed on neonatal lymphocytes and is a known modulator of TCR signaling. To further ...

Lau H, Deng YM, Xu X, Sessions W, Barr IG. Rapid detection of new B/Victoria-lineage haemagglutinin variants of influenza B viruses by pyrosequencing. Diagn Microbiol Infect Dis. 2018 Nov 13..  Abstract  
submitted by kickingbird at Dec, 13, 2018 from Diagn Microbiol Infect Dis. 2018 Nov 13. (via https://www.ncbi.nlm.nih.gov/pubmed/30528425)
During 2016/2017, several antigenically and genetically distinct variant viruses of the influenza B/Victoria/2/87-lineage (B/Vic) viruses, which have either deletions or mutations in the haemagglutinin ...

Radigan KA, et al. Influenza A Virus Infection Induces Muscle Wasting via IL-6 Regulation of the E3 Ubiquitin Ligase Atrogin-1. J Immunol. 2018 Dec 7..  Abstract  
submitted by kickingbird at Dec, 13, 2018 from J Immunol. 2018 Dec 7. (via https://www.ncbi.nlm.nih.gov/pubmed/30530483)
Muscle dysfunction is common in patients with adult respiratory distress syndrome and is associated with morbidity that can persist for years after discharge. In a mouse model of severe influenza A pneumonia, ...

Zhang H, et al. Complete Genome Sequence of an Influenza C Virus Strain Identified from a Sick Calf in the United States. Microbiol Resour Announc. 2018 Jul 12;7(1)..  Abstract  
submitted by kickingbird at Dec, 13, 2018 from Microbiol Resour Announc. 2018 Jul 12;7(1). (via https://www.ncbi.nlm.nih.gov/pubmed/30533603)
Influenza C virus (ICV) has been identified for the first time from bovine respiratory disease complex (BRDC) samples in the United States. Here, we report the complete genome sequence of the strain C/bovine/Montana/12/2016, ...

Zeller MA, et al. Complete Genome Sequences of Two Novel Human-Like H3N2 Influenza A Viruses, A/swine/Oklahoma/65980/2017 (H3N2) and A/Swine/Oklahoma/65260/2017 (H3N2), Detected in Swine in the United States. Microbiol Resour Announc. 2018 Nov 21;7(20).  Abstract  
submitted by kickingbird at Dec, 13, 2018 from Microbiol Resour Announc. 2018 Nov 21;7(20) (via https://www.ncbi.nlm.nih.gov/pubmed/30533826)
Two novel human-like H3N2 influenza A virus strains, A/swine/Oklahoma/65980/2017 (H3N2) and A/swine/Oklahoma/65260/2017 (H3N2), were isolated from porcine samples submitted to the Iowa State University ...

Sangsiriwut K, et al. Complete Genomic Sequences of Highly Pathogenic H5N1 Avian Influenza Viruses Obtained Directly from Human Autopsy Specimens. Microbiol Resour Announc. 2018 Dec 6;7(22).  Abstract  
submitted by kickingbird at Dec, 13, 2018 from Microbiol Resour Announc. 2018 Dec 6;7(22) (via https://www.ncbi.nlm.nih.gov/pubmed/30533850)
The complete genomic sequences of H5N1 highly pathogenic avian influenza (HPAI) viruses were directly obtained from lung, trachea, and colon tissues and an intestinal fecal sample of a patient by using ...

Abdul-Cader MS, et al. Antiviral response elicited against avian influenza virus infection following activation of toll-like receptor (TLR)7 signaling pathway is attributable to interleukin (IL)-1β production. BMC Res Notes. 2018 Dec 4;11(1):859..  Abstract  
submitted by kickingbird at Dec, 9, 2018 from BMC Res Notes. 2018 Dec 4;11(1):859. (via https://www.ncbi.nlm.nih.gov/pubmed/30514372)
OBJECTIVE: Single stranded ribonucleic acid (ssRNA) binds to toll-like receptor (TLR)7 leading to recruitment of immune cells and production of pro-inflammatory cytokines, which has been shown in mammals. ...

Vahey MD, Fletcher DA. Low-Fidelity Assembly of Influenza A Virus Promotes Escape from Host Cells. Cell. 2018 Nov 27.  Abstract  
submitted by kickingbird at Dec, 9, 2018 from Cell. 2018 Nov 27 (via https://www.ncbi.nlm.nih.gov/pubmed/30503209)
Influenza viruses inhabit a wide range of host environments using a limited repertoire of protein components. Unlike viruses with stereotyped shapes, influenza produces virions with significant morphological ...

Zhang X, et al. Tissue tropisms opt for transmissible reassortants during avian and swine influenza A virus co-infection in swine. PLoS Pathog. 2018 Dec 3;14(12).  Abstract  
submitted by kickingbird at Dec, 9, 2018 from PLoS Pathog. 2018 Dec 3;14(12) (via https://www.ncbi.nlm.nih.gov/pubmed/30507946)
Genetic reassortment between influenza A viruses (IAVs) facilitate emergence of pandemic strains, and swine are proposed as a "mixing vessel" for generating reassortants of avian and mammalian IAVs that ...

Tan KS, et al. Comparative Transcriptomic and Metagenomic Analyses of Influenza Virus-Infected Nasal Epithelial Cells From Multiple Individuals Reveal Specific Nasal-Initiated Signatures. Front Microbiol. 2018 Nov 14;9:2685.  Abstract  
submitted by kickingbird at Dec, 6, 2018 from Front Microbiol. 2018 Nov 14;9:2685 (via https://www.ncbi.nlm.nih.gov/pubmed/30487780)
In vitro and in vivo research based on cell lines and animals are likely to be insufficient in elucidating authentic biological and physiological phenomena mimicking human systems, especially for generating ...

Long JS, Mistry B, Haslam SM, Barclay WS. Host and viral determinants of influenza A virus species specificity. Nat Rev Microbiol. 2018 Nov 28.  Abstract  
submitted by kickingbird at Dec, 6, 2018 from Nat Rev Microbiol. 2018 Nov 28 (via https://www.nature.com/articles/s41579-018-0115-z)
Influenza A viruses cause pandemics when they cross between species and an antigenically novel virus acquires the ability to infect and transmit between these new hosts. The timing of pandemics is currently ...

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