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Lu G, Ou J, Cai S, Lai Z, Zhong L, Yin X, Li S. Canine Interferon-Inducible Transmembrane Protein Is a Host Restriction Factor That Potently Inhibits Replication of Emerging Canine Influenza Virus. Front Immunol. 2021 Oct 14;12:710705.  Abstract  
submitted by kickingbird at Nov, 2, 2021 from Front Immunol. 2021 Oct 14;12:710705 (via https://www.frontiersin.org/articles/10.3389/fimmu.2021.7107)
Canine influenza virus (CIV) is an emerging virus that is associated with major hidden hazards to the canine population and public health. Until now, how canine uses its innate immunity to restrict CIV ...

Kinoshita T, Watanabe K, Sakurai Y, Nishi K, Yoshi. Co-infection of SARS-CoV-2 and influenza virus causes more severe and prolonged pneumonia in hamsters. Sci Rep. 2021 Oct 28;11(1):21259.  Abstract  
submitted by kickingbird at Nov, 1, 2021 from Sci Rep. 2021 Oct 28;11(1):21259 (via https://www.nature.com/articles/s41598-021-00809-2)
Coronavirus disease 2019 (COVID-19) caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is currently a serious public health concern worldwide. Notably, co-infection with other pathogens ...

Guo J, Song W, Ni X, Liu W, Wu J, Xia W, Zhou X, W. Pathogen change of avian influenza virus in the live poultry market before and after vaccination of poultry in southern China. Virol J. 2021 Oct 29;18(1):213.  Abstract  
submitted by kickingbird at Nov, 1, 2021 from Virol J. 2021 Oct 29;18(1):213 (via https://virologyj.biomedcentral.com/articles/10.1186/s12985-)
Background: The fifth wave of H7N9 avian influenza virus caused a large number of human infections and a large number of poultry deaths in China. Since September 2017, mainland China has begun to vaccinate ...

Guo J, Wang Y, Zhao C, Gao X, Zhang Y, Li J, Wang. Molecular characterization, receptor binding property and replication in chickens and mice of H9N2 avian influenza viruses isolated from chickens, peafowls and wild birds in eastern China. Emerg Microbes Infect. 2021 Oct 28:1-39.  Abstract  
submitted by kickingbird at Oct, 29, 2021 from Emerg Microbes Infect. 2021 Oct 28:1-39 (via https://www.tandfonline.com/doi/full/10.1080/22221751.2021.1)
H9N2 avian influenza viruses are widely prevalent in birds and pose an increasing threat to humans because of their enhanced virulence and transmissibility in mammals. Active surveillance on the prevalence ...

Su W, Harfoot R, Su YCF, DeBeauchamp J, Joseph U,. Ancestral sequence reconstruction pinpoints adaptations that enable avian influenza virus transmission in pigs. Nat Microbiol. 2021 Oct 26.  Abstract  
submitted by kickingbird at Oct, 28, 2021 from Nat Microbiol. 2021 Oct 26 (via https://www.nature.com/articles/s41564-021-00976-y)
Understanding the evolutionary adaptations that enable avian influenza viruses to transmit in mammalian hosts could allow better detection of zoonotic viruses with pandemic potential. We applied ancestral ...

Giacchetta I, Primieri C, Cavalieri R, Domnich A,. The burden of seasonal influenza in Italy: A systematic review of influenza-related complications, hospitalizations, and mortality. Influenza Other Respir Viruses. 2021 Oct 26.  Abstract  
submitted by kickingbird at Oct, 28, 2021 from Influenza Other Respir Viruses. 2021 Oct 26 (via https://onlinelibrary.wiley.com/doi/10.1111/irv.12925)
Reliable country-specific data on influenza burden play a crucial role in informing prevention and control measures. Our purpose was to provide a comprehensive summary of the available evidence on the ...

Ankhanbaatar U, Sainnokhoi T, Settypalli TBK, Datt. Isolation and Identification of a Highly Pathogenic Avian Influenza H5N6 Virus from Migratory Waterfowl in Western Mongolia. J Wildl Dis. 2021 Oct 26.  Abstract  
submitted by kickingbird at Oct, 27, 2021 from J Wildl Dis. 2021 Oct 26 (via https://pubmed.ncbi.nlm.nih.gov/34699593/)
In April 2020, two Whooper Swans (Cygnus cygnus) and one Swan Goose (Anser cygnoides) were found dead at three different locations in western Mongolia. Virus isolation from organs taken from the carcasses ...

Nezworski J, St Charles KM, Malladi S, Ssematimba. A Retrospective Study of Early vs. Late Virus Detection and Depopulation on Egg Laying Chicken Farms Infected with Highly Pathogenic Avian Influenza Virus During the 2015 H5N2 Outbreak in the United S. Avian Dis. 2021 Sep;65(3):474-482.  Abstract  
submitted by kickingbird at Oct, 27, 2021 from Avian Dis. 2021 Sep;65(3):474-482 (via https://bioone.org/journals/avian-diseases/volume-65/issue-3)
The 2015 highly pathogenic avian influenza (HPAI) H5N2 outbreak affected more than 200 Midwestern U.S. poultry premises. Although each affected poultry operation incurred substantial losses, some operations ...

Xia YL, Li W, Li Y, Ji XL, Fu YX, Liu SQ. A Deep Learning Approach for Predicting Antigenic Variation of Influenza A H3N2. Comput Math Methods Med. 2021 Oct 16;2021:9997669..  Abstract  
submitted by kickingbird at Oct, 27, 2021 from Comput Math Methods Med. 2021 Oct 16;2021:9997669. (via https://www.hindawi.com/journals/cmmm/2021/9997669/)
Modeling antigenic variation in influenza (flu) virus A H3N2 using amino acid sequences is a promising approach for improving the prediction accuracy of immune efficacy of vaccines and increasing the efficiency ...

Arunkumar GA, Bhavsar D, Li T, Strohmeier S, Chrom. Functionality of the putative surface glycoproteins of the Wuhan spiny eel influenza virus. Nat Commun. 2021 Oct 25;12(1):6161.  Abstract  
submitted by kickingbird at Oct, 27, 2021 from Nat Commun. 2021 Oct 25;12(1):6161 (via https://www.nature.com/articles/s41467-021-26409-2)
A panel of influenza virus-like sequences were recently documented in fish and amphibians. Of these, the Wuhan spiny eel influenza virus (WSEIV) was found to phylogenetically cluster with influenza B viruses ...

Zecchin B, Goujgoulova G, Monne I, Salviato A, Sch. Evolutionary Dynamics of H5 Highly Pathogenic Avian Influenza Viruses (Clade Circulating in Bulgaria in 2019-2021. Viruses. 2021 Oct 16;13(10):2086.  Abstract  
submitted by kickingbird at Oct, 27, 2021 from Viruses. 2021 Oct 16;13(10):2086 (via https://www.mdpi.com/1999-4915/13/10/2086)
The first detection of a Highly Pathogenic Avian Influenza (HPAI) H5N8 virus in Bulgaria dates back to December 2016. Since then, many outbreaks caused by HPAI H5 viruses from clade have been ...

Na EJ, Kim YS, Kim YJ, Park JS, Oem JK. Genetic Characterization and Pathogenicity of H7N7 and H7N9 Avian Influenza Viruses Isolated from South Korea. Viruses. 2021 Oct 13;13(10):2057.  Abstract  
submitted by kickingbird at Oct, 27, 2021 from Viruses. 2021 Oct 13;13(10):2057 (via https://www.mdpi.com/1999-4915/13/10/2057)
H7 low pathogenic avian influenza viruses (LPAIVs) can mutate into highly pathogenic avian influenza viruses (HPAIVs). In addition to avian species, H7 avian influenza viruses (AIVs) also infect humans. ...

Wang Z, Ye S, Yao C, Wang J, Mao J, Xu L, Liu Y, F. Antiviral Activity of Canine RIG-I against Canine Influenza Virus and Interactions between Canine RIG-I and CIV. Viruses. 2021 Oct 12;13(10):2048.  Abstract  
submitted by kickingbird at Oct, 27, 2021 from Viruses. 2021 Oct 12;13(10):2048 (via https://www.mdpi.com/1999-4915/13/10/2048)
RIG-I functions as a virus sensor that induces a cellular antiviral response. Although it has been investigated in other species, there have been no further studies to date on canine RIG-I against canine ...

Ma T, Nagy A, Xu G, Xin L, Bao D, Lu C, Niu S, Wu. RNA-Seq Analysis of Influenza A Virus-Induced Transcriptional Changes in Mice Lung and Its Possible Implications for the Virus Pathogenicity in Mice. Viruses. 2021 Oct 8;13(10):2031.  Abstract  
submitted by kickingbird at Oct, 27, 2021 from Viruses. 2021 Oct 8;13(10):2031 (via https://www.mdpi.com/1999-4915/13/10/2031)
The influenza A virus (IAV) is an important cause of respiratory disease worldwide. It is well known that alveolar epithelial cells are the target cells for the IAV, but there is relatively limited knowledge ...

Cáceres CJ, Rajao DS, Perez DR. Airborne Transmission of Avian Origin H9N2 Influenza A Viruses in Mammals. Viruses. 2021 Sep 24;13(10):1919.  Abstract  
submitted by kickingbird at Oct, 27, 2021 from Viruses. 2021 Sep 24;13(10):1919 (via https://www.mdpi.com/1999-4915/13/10/1919)
Influenza A viruses (IAV) are widespread viruses affecting avian and mammalian species worldwide. IAVs from avian species can be transmitted to mammals including humans and, thus, they are of inherent ...

Park MJ, Cha RM, Kye SJ, Lee YN, Kim NY, Baek YG,. Pathogenicity of H5N8 High Pathogenicity Avian Influenza Virus in Chickens and Ducks from South Korea in 2020-2021. Viruses. 2021 Sep 23;13(10):1903.  Abstract  
submitted by kickingbird at Oct, 27, 2021 from Viruses. 2021 Sep 23;13(10):1903 (via https://www.mdpi.com/1999-4915/13/10/1903)
During the 2020-2021 winter season, an outbreak of clade H5N8 high pathogenicity avian influenza (HPAI) virus occurred in South Korea. Here, we evaluated the pathogenicity and transmissibility ...

Jang Y, Seo SH. H5 cleavage-site peptide vaccine protects chickens from lethal infection by highly pathogenic H5 avian influenza viruses. Arch Virol. 2021 Oct 25.  Abstract  
submitted by kickingbird at Oct, 26, 2021 from Arch Virol. 2021 Oct 25 (via https://link.springer.com/article/10.1007%2Fs00705-021-05284)
Highly pathogenic H5Nx avian influenza viruses constantly threaten the poultry industry and humans and have pandemic potential. These viruses continuously evolve, requiring a universal vaccine to protect ...

Kong X, Guan L, Shi J, Kong H, Zhang Y, Zeng X, Ti. A single-amino-acid mutation at position 225 in hemagglutinin attenuates H5N6 influenza virus in mice. Emerg Microbes Infect. 2021 Oct 22:1-21.  Abstract  
submitted by kickingbird at Oct, 26, 2021 from Emerg Microbes Infect. 2021 Oct 22:1-21 (via https://www.tandfonline.com/doi/full/10.1080/22221751.2021.1)
The highly pathogenic avian influenza H5N6 viruses are widely circulating in poultry and wild birds, and have caused 38 human infections including 21 deaths; however, the key genetic determinants of the ...

Zhao J, He W, Lu M, He H, Lai A. Emergence and Characterization of a Novel Reassortant Canine Influenza Virus Isolated from Cats. Pathogens. 2021 Oct 14;10(10):1320.  Abstract  
submitted by kickingbird at Oct, 26, 2021 from Pathogens. 2021 Oct 14;10(10):1320 (via https://www.mdpi.com/2076-0817/10/10/1320)
Cats are susceptible to a wide range of influenza A viruses (IAV). Furthermore, cats can serve as an intermediate host, and transfer avian influenza virus (AIV) H7N2 to a veterinarian. In this report, ...

Kang HJ, Chu KB, Yoon KW, Eom GD, Mao J, Kim MJ, L. Neuraminidase in Virus-like Particles Contributes to the Protection against High Dose of Avian Influenza Virus Challenge Infection. Pathogens. 2021 Oct 7;10(10):1291.  Abstract  
submitted by kickingbird at Oct, 26, 2021 from Pathogens. 2021 Oct 7;10(10):1291 (via https://www.mdpi.com/2076-0817/10/10/1291)
Neuraminidase is an important target for influenza vaccination. In this study, we generated avian influenza VLPs, expressing hemagglutinin (HA), neuraminidase (NA), HA and NA co-expressed (HANA), to evaluate ...

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