Takada K, et al. A humanized MDCK cell line for the efficient isolation and propagation of human influenza viruses. Nat Microbiol. 2019 Apr 29.. Abstract
submitted by kickingbird at May, 2, 2019 from Nat Microbiol. 2019 Apr 29. (via https://www.nature.com/articles/s41564-019-0433-6)
Here, we developed hCK, a Madin-Darby canine kidney (MDCK) cell line that expresses high levels of human influenza virus receptors and low levels of avian virus receptors. hCK cells supported human A/H3N2 ... Maslanka Figueroa S, et al. Influenza A virus mimetic nanoparticles trigger selective cell uptake. Proc Natl Acad Sci U S A. 2019 Apr 29.. Abstract
submitted by kickingbird at May, 2, 2019 from Proc Natl Acad Sci U S A. 2019 Apr 29. (via https://www.pnas.org/content/early/2019/04/25/1902563116)
Poor target cell specificity is currently a major shortcoming of nanoparticles (NPs) used for biomedical applications. It causes significant material loss to off-target sites and poor availability at the ... Soh YS, et al. Comprehensive mapping of adaptation of the avian influenza polymerase protein PB2 to humans. Elife. 2019 Apr 30;8. Abstract
submitted by kickingbird at May, 2, 2019 from Elife. 2019 Apr 30;8 (via https://elifesciences.org/articles/45079)
Viruses like influenza are infamous for their ability to adapt to new hosts. Retrospective studies of natural zoonoses and passaging in the lab have identified a modest number of host-adaptive mutations. ... Hornick EE, et al. Dendritic cell NLRC4 regulates influenza A virus-specific CD4 T cell responses through FasL expression.. J Clin Invest. 2019 Apr 30;130. Abstract
submitted by kickingbird at May, 2, 2019 from J Clin Invest. 2019 Apr 30;130 (via https://www.jci.org/articles/view/124937)
Influenza A virus (IAV)-specific T cell responses are important correlates of protection during primary and subsequent infections. Generation and maintenance of robust IAV-specific T cell responses relies ... Elbahesh H, Gerlach T, Saletti G, Rimmelzwaan G. Response Modifiers: Tweaking the Immune Response Against Influenza A Virus. Front Immunol. 2019 Apr 12;10:809. Abstract
submitted by kickingbird at May, 1, 2019 from Front Immunol. 2019 Apr 12;10:809 (via https://www.frontiersin.org/articles/10.3389/fimmu.2019.0080)
Despite causing pandemics and yearly epidemics that result in significant morbidity and mortality, our arsenal of options to treat influenza A virus (IAV) infections remains limited and is challenged by ... Liu X, et al. Evidence for a novel mechanism of influenza A virus host adaption modulated by PB2-627. FEBS J. 2019 Apr 29.. Abstract
submitted by kickingbird at May, 1, 2019 from FEBS J. 2019 Apr 29. (via https://febs.onlinelibrary.wiley.com/doi/abs/10.1111/febs.14)
Influenza virus cross-species transmission is restricted by the host, but viruses overcome this restriction by accumulating mutations which allow them to adapt to a new host. Among the many factors which ... Shen X, Pu Z, Irwin DM, Shen Y. No gene communication between the human H3N2 and H1N1 pandemic 2009 influenza A viruses. J Infect. 2019 Apr 25. Abstract
submitted by kickingbird at Apr, 29, 2019 from J Infect. 2019 Apr 25 (via https://www.journalofinfection.com/article/S0163-4453(19)301)
Recently, a study in this journal suggested that the 2014 H1N1 pandemic 2009 (H1N1/pdm2009) had gene communication with 2016/2017 H3N2. The influenza A H1N1/pdm2009 virus, a novel swine-derived, triple ... Xiang B, et al. Genetic characterization of H7N4 avian influenza virus in China in 2018. J Infect. 2019 Apr 25. Abstract
submitted by kickingbird at Apr, 29, 2019 from J Infect. 2019 Apr 25 (via https://www.journalofinfection.com/article/S0163-4453(19)301)
Recent study in this journal reported that the first case of human infection with H7N4 avian influenza virus (AIV) was confirmed in China.1 Subsequently, 11 H7N4 AIVs were isolated from poultries, 4 viruses ... Guo F, Shen X, Irwin DM, Shen Y. Avian influenza A viruses H5Nx (N1, N2, N6 and N8) show different adaptations of their codon usage patterns to their hosts. J Infect. 2019 Apr 25. pii: S0163-4453(19)30126-4. Abstract
submitted by kickingbird at Apr, 29, 2019 from J Infect. 2019 Apr 25. pii: S0163-4453(19)30126-4 (via https://www.journalofinfection.com/article/S0163-4453(19)301)
A recent study in this journal identified three H5 highly pathogenic avian influenza A viruses (HPAIVs) with differing NA subtypes (N1, N6 and N8) and revealed that while the three isolates were all highly ... Poen MJ, et al. Co-circulation of genetically distinct highly pathogenic avian influenza A clade 2.3.4.4 (H5N6) viruses in wild waterfowl and poultry in Europe and East Asia, 2017~18. Virus Evol. 2019 Apr 22;5(1):vez004. Abstract
submitted by kickingbird at Apr, 28, 2019 from Virus Evol. 2019 Apr 22;5(1):vez004 (via https://academic.oup.com/ve/article/5/1/vez004/5476200)
Highly pathogenic avian influenza (HPAI) H5 clade 2.3.4.4 viruses were first introduced into Europe in late 2014 and re-introduced in late 2016, following detections in Asia and Russia. In contrast to ... Holwerda M, et al. Determining the Replication Kinetics and Cellular Tropism of Influenza D Virus on Primary Well-Differentiated Human Airway Epithelial Cells. Viruses. 2019 Apr 24;11(4).. Abstract
submitted by kickingbird at Apr, 28, 2019 from Viruses. 2019 Apr 24;11(4). (via https://www.mdpi.com/1999-4915/11/4/377)
Influenza viruses are notorious pathogens that frequently cross the species barrier with often severe consequences for both animal and human health. In 2011, a novel member of the Orthomyxoviridae family, ... Novianti AN, et al. Whole-Genome Sequence of an Avian Influenza A/H9N2 Virus Isolated from an Apparently Healthy Chicken at a Live-Poultry Market in Indonesia. Microbiol Resour Announc. 2019 Apr 25;8(17).. Abstract
submitted by kickingbird at Apr, 28, 2019 from Microbiol Resour Announc. 2019 Apr 25;8(17). (via https://mra.asm.org/content/8/17/e01671-18)
We isolated an avian influenza A/H9N2 virus from an apparently healthy chicken at a live-poultry market in January 2018. This is the first report of a whole-genome sequence of A/H9N2 virus in Indonesia. ... Mi?o S, et al. Equine influenza virus in Asia: phylogeographic pattern and molecular features revealed the circulation of an autochthonous lineage. J Virol. 2019 Apr 24.. Abstract
submitted by kickingbird at Apr, 27, 2019 from J Virol. 2019 Apr 24. (via https://jvi.asm.org/content/early/2019/04/18/JVI.00116-19)
Equine influenza virus (EIV) causes severe acute respiratory disease in horses. Currently, the strains belonging to the H3N8 genotype are divided into two clades, Florida clade 1 (FC1) and Florida clade ... Kukushkin VI, et al. Highly sensitive detection of influenza virus with SERS aptasensor. PLoS One. 2019 Apr 25;14(4):e0216247. Abstract
submitted by kickingbird at Apr, 27, 2019 from PLoS One. 2019 Apr 25;14(4):e0216247 (via https://journals.plos.org/plosone/article?id=10.1371/journal)
Highly sensitive and rapid technology of surface enhanced Raman scattering (SERS) was applied to create aptasensors for influenza virus detection. SERS achieves 106?109 times signal amplification, yielding ... Hom N, Gentles L, Bloom JD, Lee KK. Deep mutational scan of the highly conserved influenza A M1 matrix protein reveals substantial intrinsic mutational tolerance. J Virol. 2019 Apr 24. Abstract
submitted by kickingbird at Apr, 27, 2019 from J Virol. 2019 Apr 24 (via https://jvi.asm.org/content/early/2019/04/18/JVI.00161-19)
Influenza A virus matrix protein M1 is involved in multiple stages of the viral infectious cycle. Despite its functional importance, our present understanding of this essential viral protein is limited. ... Hana A Pawestri, et al. Viral factors associated with the high mortality of human infections with clade 2.1 influenza A/H5N1 virus in Indonesia. Clinical Infectious Diseases 26 April 2019. Abstract
submitted by kickingbird at Apr, 27, 2019 from Clinical Infectious Diseases 26 April 2019 (via https://academic.oup.com/cid/advance-article-abstract/doi/10)
AbstractBackgroundSince their emergence in Indonesia in 2005, 200 human infections with clade 2.1 highly pathogenic avian influenza A/H5N1 virus have been reportedassociated with exceptionally high mortality ... Barman S, et al. Continuing evolution of highly pathogenic H5N1 viruses in Bangladeshi live poultry markets. Emerg Microbes Infect. 2019;8(1):650-661. Abstract
submitted by kickingbird at Apr, 25, 2019 from Emerg Microbes Infect. 2019;8(1):650-661 (via https://www.tandfonline.com/doi/full/10.1080/22221751.2019.1)
Since November 2008, we have conducted active avian influenza surveillance in Bangladesh. Clades 2.2.2, 2.3.4.2, and 2.3.2.1a of highly pathogenic avian influenza H5N1 viruses have all been identified ... Koel BF, et al. Epistatic interactions can moderate the antigenic effect of substitutions in haemagglutinin of influenza H3N2 virus. J Gen Virol. 2019 Apr 24.. Abstract
submitted by kickingbird at Apr, 25, 2019 from J Gen Virol. 2019 Apr 24. (via https://jgv.microbiologyresearch.org/content/journal/jgv/10.)
We previously showed that single amino acid substitutions at seven positions in haemagglutinin determined major antigenic change of influenza H3N2 virus. Here, the impact of two such substitutions was ... Westera L, et al. Poly-ADP Ribosyl Polymerase 1 (PARP1) Regulates Influenza A Virus Polymerase. Adv Virol. 2019 Mar 19;2019:8512363.. Abstract
submitted by kickingbird at Apr, 25, 2019 from Adv Virol. 2019 Mar 19;2019:8512363. (via https://www.hindawi.com/journals/av/2019/8512363/)
Influenza A viruses (IAV) are evolutionarily successful pathogens, capable of infecting a number of avian and mammalian species and responsible for pandemic and seasonal epidemic disease in humans. To ... Alfardan R, Guo C, Toth LA, Nie D. Impaired Recovery from Influenza A/X-31(H3N2) Infection in Mice with 8-Lipoxygenase Deficiency. Med Sci (Basel). 2019 Apr 12;7(4).. Abstract
submitted by kickingbird at Apr, 25, 2019 from Med Sci (Basel). 2019 Apr 12;7(4). (via https://www.mdpi.com/2076-3271/7/4/60)
Lipoxygenase-derived lipid mediators can modulate inflammation and are stimulated in response to influenza infections. We report an effect of 8-lipoxygenase (ALOX8) on the recovery of mice after infection ... 5165 items, 20/Page, Page[104/259][|<<] [|<] [101] [102] [103] [104] [105] [106] [107] [108] [109] [110] [>|] [>>|] |
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