Simon B, et al. Whole Genome Sequencing of A(H3N2) Influenza Viruses Reveals Variants Associated with Severity during the 2016~2017 Season. Viruses. 2019 Jan 28;11(2). Abstract
submitted by kickingbird at Jan, 31, 2019 from Viruses. 2019 Jan 28;11(2) (via https://www.ncbi.nlm.nih.gov/pubmed/30695992)
Influenza viruses cause a remarkable disease burden and significant morbidity and mortality worldwide, and these impacts vary between seasons. To understand the mechanisms associated with these differences, ...
Ohkusa Y, et al. Inquiry into some gap among oseltamivir use and severe abnormal behavior in Japanese children and adolescents with influenza. Drug Discov Ther. 2018;12(6):381-383. Abstract
submitted by kickingbird at Jan, 26, 2019 from Drug Discov Ther. 2018;12(6):381-383 (via https://www.ncbi.nlm.nih.gov/pubmed/30674775)
The Fukushima research has examined data form a cohort study of 10,000 Japanese children under 18 years old with influenza during three months to demonstrate that the relative risk of A-type abnormal behavior ...
Takashita E, et al. Detection of influenza A(H3N2) viruses exhibiting reduced susceptibility to the novel cap-dependent endonuclease inhibitor baloxavir in Japan, December 2018. Euro Surveill. 2019 Jan;24(3).. Abstract
submitted by kickingbird at Jan, 26, 2019 from Euro Surveill. 2019 Jan;24(3). (via https://www.ncbi.nlm.nih.gov/pubmed/30670142)
The novel cap-dependent endonuclease inhibitor baloxavir marboxil was approved for the treatment of influenza virus infection in Japan in February 2018. Two influenza A(H3N2) viruses carrying an I38T substitution ...
Koutsakos M, Kedzierska K, Subbarao K. Immune Responses to Avian Influenza Viruses. J Immunol. 2019 Jan 15;202(2):382-391.. Abstract
submitted by kickingbird at Jan, 23, 2019 from J Immunol. 2019 Jan 15;202(2):382-391. (via https://www.ncbi.nlm.nih.gov/pubmed/30617120)
Avian influenza A viruses (IAVs) naturally infect different avian species, and aquatic birds are their natural reservoir. Sporadically, avian IAVs can be transmitted to humans, and some, such as H5N1 and ...
Hatayama K, et al. Combined effect of anti-high-mobility group box-1 monoclonal antibody and peramivir against influenza A virus-induced pneumonia in mice. J Med Virol. 2019 Mar;91(3):361-369.. Abstract
submitted by kickingbird at Jan, 23, 2019 from J Med Virol. 2019 Mar;91(3):361-369. (via https://www.ncbi.nlm.nih.gov/pubmed/30281823)
Human pandemic H1N1 2009 influenza virus causes significant morbidity and mortality with severe acute lung injury due to the excessive inflammatory reaction, even with neuraminidase inhibitor use. The ...
Yang Y, et al. Comparison between human infections caused by highly and low pathogenic H7N9 avian influenza viruses in Wave Five: clinical and virological findings. J Infect. 2019 Jan 18. Abstract
submitted by kickingbird at Jan, 23, 2019 from J Infect. 2019 Jan 18 (via https://www.ncbi.nlm.nih.gov/pubmed/30664912)
OBJECTIVE: The newly emerged highly pathogenic (HP) H7N9 avian influenza virus during Wave Five has caused 28 human infections, while differences in disease severity between low pathogenic (LP)- and HP-H7N9 ...
Parra-Rojas C, Messling VV, Hernandez-Vargas EA. Adjuvanted influenza vaccine dynamics. Sci Rep. 2019 Jan 11;9(1):73. Abstract
submitted by kickingbird at Jan, 15, 2019 from Sci Rep. 2019 Jan 11;9(1):73 (via https://www.ncbi.nlm.nih.gov/pubmed/30635599)
Adjuvanted influenza vaccines constitute a key element towards inducing neutralizing antibody responses in populations with reduced responsiveness, such as infants and elderly subjects, as well as in devising ...
Lu FS, Hattab MW, Clemente CL, et al. Improved state-level influenza nowcasting in the United States leveraging Internet-based data and network approaches. Nat Commun. 2019 Jan 11;10(1):147. Abstract
submitted by kickingbird at Jan, 14, 2019 from Nat Commun. 2019 Jan 11;10(1):147 (via https://www.ncbi.nlm.nih.gov/pubmed/30635558)
In the presence of health threats, precision public health approaches aim to provide targeted, timely, and population-specific interventions. Accurate surveillance methodologies that can estimate infectious ...
Lu C, Xing Y, Cai H, Shi Y, Liu J, Huang Y. Identification and analysis of long non-coding RNAs in response to H5N1 influenza viruses in duck (Anas platyrhynchos). BMC Genomics. 2019 Jan 11. Abstract
submitted by kickingbird at Jan, 14, 2019 from BMC Genomics. 2019 Jan 11 (via https://www.ncbi.nlm.nih.gov/pubmed/30634898)
BACKGROUND: Long non-coding RNAs (lncRNAs) are important component of mammalian genomes, where their numbers are even larger than that of protein-coding genes. For example, human (Homo sapiens) (96,308 ...
Chastagner A, et al. Spatiotemporal Distribution and Evolution of the A/H1N1 2009 Pandemic Influenza Virus in Pigs in France from 2009 to 2017: Identification of a Potential Swine-Specific Lineage. J Virol. 2018 Nov 27;92(24). Abstract
submitted by kickingbird at Jan, 14, 2019 from J Virol. 2018 Nov 27;92(24) (via https://www.ncbi.nlm.nih.gov/pubmed/30258006)
The H1N1 influenza virus responsible for the most recent pandemic in 2009 (H1N1pdm) has spread to swine populations worldwide while it replaced the previous seasonal H1N1 virus in humans. In France, surveillance ...
Htwe KTZ, et al. Phylogeographic analysis of human influenza A and B viruses in Myanmar, 2010-2015. PLoS One. 2019 Jan 10;14(1):e0210550. Abstract
submitted by kickingbird at Jan, 14, 2019 from PLoS One. 2019 Jan 10;14(1):e0210550 (via https://www.ncbi.nlm.nih.gov/pubmed/30629691)
We investigated the circulation patterns of human influenza A and B viruses in Myanmar between 2010 and 2015 by analyzing full HA genes. Upper respiratory tract specimens were collected from patients with ...
Martínez A, et al. Risk factors associated with severe outcomes in adult hospitalized patients according to influenza type and subtype. PLoS One. 2019 Jan 11;14(1):e0210353. Abstract
submitted by kickingbird at Jan, 14, 2019 from PLoS One. 2019 Jan 11;14(1):e0210353 (via https://www.ncbi.nlm.nih.gov/pubmed/30633778)
Seasonal influenza is a cause of hospitalization, especially in people with underlying disease or extreme age, and its severity may differ depending on the types and subtypes of circulating viruses. We ...
Gounder AP, Boon ACM. Influenza Pathogenesis: The Effect of Host Factors on Severity of Disease. J Immunol. 2019 Jan 15;202(2):341-350.. Abstract
submitted by kickingbird at Jan, 9, 2019 from J Immunol. 2019 Jan 15;202(2):341-350. (via https://www.ncbi.nlm.nih.gov/pubmed/30617115)
Influenza viruses continue to be a major global health threat. Severity and clinical outcome of influenza disease is determined by both viral and host factors. Viral factors have long been the subject ...
Berger KA, et al. The Geographic Variation of Surveillance and Zoonotic Spillover Potential of Influenza Viruses in Domestic Poultry and Swine. Open Forum Infect Dis. 2018 Nov 27. Abstract
submitted by kickingbird at Jan, 9, 2019 from Open Forum Infect Dis. 2018 Nov 27 (via https://www.ncbi.nlm.nih.gov/pubmed/30619908)
Background: Avian and swine influenza viruses circulate worldwide and pose threats to both animal and human health. The design of global surveillance strategies is hindered by information gaps on the geospatial ...
Peci A, et al. Effect of absolute and relative humidity, temperature and wind speed on influenza activity in Toronto, Canada. Appl Environ Microbiol. 2019 Jan 4. Abstract
submitted by kickingbird at Jan, 7, 2019 from Appl Environ Microbiol. 2019 Jan 4 (via https://www.ncbi.nlm.nih.gov/pubmed/30610079)
The occurrence of influenza in different climates is shown to be associated with multiple meteorological factors. Incidence of influenza has been reported to increase during rainy seasons in tropical climates ...
Peretz A, Azrad M, Blum A. Influenza virus and Atherosclerosis. QJM. 2019 Jan 3.. Abstract
submitted by kickingbird at Jan, 7, 2019 from QJM. 2019 Jan 3. (via https://www.ncbi.nlm.nih.gov/pubmed/30605546)
Influenza viruses infect the upper respiratory system, causing usually a self-limited disease with mild respiratory symptoms. Acute lung injury, pulmonary microvascular leakage and cardiovascular collapse ...
Pawestri HA, Nugraha AA, Hariastuti NI, Setiawaty. Detection of neuraminidase inhibitor-resistant influenza A (H1N1)pdm09 viruses obtained from influenza surveillance in Indonesia. SAGE Open Med. 2018 Dec 10;6:2050312118818293. Abstract
submitted by kickingbird at Dec, 24, 2018 from SAGE Open Med. 2018 Dec 10;6:2050312118818293 (via https://www.ncbi.nlm.nih.gov/pubmed/30574303)
Background: Influenza antiviral resistance has been shown to occur in many countries and is commonly found in influenza A(H1N1)pdm09 and A(H3N2). In this study, we monitored and investigated the neuraminidase ...
Yoshihara K, et al. Influenza B associated Paediatric Acute Respiratory Infection Hospitalization in Central Vietnam. Influenza Other Respir Viruses. 2018 Dec 21. Abstract
submitted by kickingbird at Dec, 24, 2018 from Influenza Other Respir Viruses. 2018 Dec 21 (via https://www.ncbi.nlm.nih.gov/pubmed/30575288)
BACKGROUND: Influenza B is one of the major etiologies for acute respiratory infections (ARI) among children worldwide; however, its clinical-epidemiological information is limited. We aimed to investigate ...
Yin R, Tran VH, Zhou X, Zheng J, Kwoh CK. Predicting antigenic variants of H1N1 influenza virus based on epidemics and pandemics using a stacking model. PLoS One. 2018 Dec 21;13(12):e0207777.. Abstract
submitted by kickingbird at Dec, 24, 2018 from PLoS One. 2018 Dec 21;13(12):e0207777. (via https://www.ncbi.nlm.nih.gov/pubmed/30576319)
H1N1 is the earliest emerging subtype of influenza A viruses with available genomic sequences, has caused several pandemics and seasonal epidemics, resulting in millions of deaths and enormous economic ...
van Asten L, et al. Estimating severity of influenza epidemics from severe acute respiratory infections (SARI) in intensive care units. Crit Care. 2018 Dec 19;22(1):351. Abstract
submitted by kickingbird at Dec, 23, 2018 from Crit Care. 2018 Dec 19;22(1):351 (via https://www.ncbi.nlm.nih.gov/pubmed/30567568)
BACKGROUND: While influenza-like-illness (ILI) surveillance is well-organized at primary care level in Europe, few data are available on more severe cases. With retrospective data from intensive care units ...
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