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2019-9-17 17:22:18
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Gouma S, Weirick M, Hensley SE. Potential antigenic mismatch of the H3N2 component of the 2019 Southern Hemisphere influenza vaccine. Clin Infect Dis. 2019 Aug 11..  Abstract  
submitted by kickingbird at Aug, 15, 2019 from Clin Infect Dis. 2019 Aug 11. (via https://academic.oup.com/cid/advance-article-abstract/doi/10)
Here, we find that the egg-adapted H3N2 component of the 2019 Southern Hemisphere influenza vaccine elicits an antibody response in ferrets that is highly focused on antigenic site A of hemagglutinin. ...

Garvey MI, et al. Lessons learnt from influenza POCT implementation in an AMU. J Hosp Infect. 2019 Aug 6.  Abstract  
submitted by kickingbird at Aug, 15, 2019 from J Hosp Infect. 2019 Aug 6 (via https://www.journalofhospitalinfection.com/article/S0195-670)
Influenza point of care tests (POCT) can speed up diagnosis and improve management of patients with influenza.1-3 Young et al discussed the impact of a POCT for influenza in an emergency department.4 The ...

Van Bennekom CM, Kerr SM, Mitchell AA. Oseltamivir exposure in pregnancy and the risk of specific birth defects. Birth Defects Res. 2019 Aug 8.  Abstract  
submitted by kickingbird at Aug, 11, 2019 from Birth Defects Res. 2019 Aug 8 (via https://onlinelibrary.wiley.com/doi/abs/10.1002/bdr2.1563)
BACKGROUND: Influenza during pregnancy contributes to maternal morbidity and mortality. Neuraminidase inhibitors, including oseltamivir, are recommended for treating women with influenza during pregnancy.METHODS: ...

Chambers CD, et al. Oseltamivir use in pregnancy: Risk of birth defects, preterm delivery, and small for gestational age infants. Birth Defects Res. 2019 Aug 8.  Abstract  
submitted by kickingbird at Aug, 11, 2019 from Birth Defects Res. 2019 Aug 8 (via https://onlinelibrary.wiley.com/doi/abs/10.1002/bdr2.1566)
BACKGROUND: Influenza infection during pregnancy increases risks for adverse outcomes for both mother and fetus. For this reason, treatment for infection or postexposure prophylaxis with a neuraminidase ...

Chang KH, et al. Gulllain-Barre Syndrome After Trivalent Influenza Vaccination in Adults. Front Neurol. 2019 Jul 24;10:768..  Abstract  
submitted by kickingbird at Aug, 11, 2019 from Front Neurol. 2019 Jul 24;10:768. (via https://www.frontiersin.org/articles/10.3389/fneur.2019.0076)
Lines of evidence suggest trivalent influenza vaccination may be associated with Guillain-Barre syndrome (GBS), an immune-mediated acute inflammatory neuropathy. On the other hand, this vaccination protects ...

Palekar R, et al. Patterns of influenza B circulation in Latin America and the Caribbean, 2010~2017. PLoS One. 2019 Aug 8;14(8):e0219595.  Abstract  
submitted by kickingbird at Aug, 11, 2019 from PLoS One. 2019 Aug 8;14(8):e0219595 (via https://journals.plos.org/plosone/article?id=10.1371/journal)
OBJECTIVE: There are limited published data about the circulation of influenza B/Victoria and B/Yamagata in Latin America and the Caribbean (LAC) and most countries have a vaccine policy that includes ...

Jha A, et al. Patterns of systemic and local inflammation in patients with asthma hospitalised with influenza. Eur Respir J. 2019 Aug 7..  Abstract  
submitted by kickingbird at Aug, 11, 2019 from Eur Respir J. 2019 Aug 7. (via https://erj.ersjournals.com/content/early/2019/07/31/1399300)
BACKGROUND: Patients with asthma are at risk of hospitalisation with influenza, but the reasons for this predisposition are unknown.STUDY SETTING: A prospective observational study of adults with PCR-confirmed ...

Naguib MM, et al. Global patterns of avian influenza A(H7): virus evolution and zoonotic threats. FEMS Microbiol Rev. 2019 Aug 5.  Abstract  
submitted by kickingbird at Aug, 8, 2019 from FEMS Microbiol Rev. 2019 Aug 5 (via https://academic.oup.com/femsre/advance-article/doi/10.1093/)
Avian influenza viruses (AIVs) continue to impose a negative impact on animal and human health worldwide. In particular, the emergence of highly pathogenic AIV H5 and, more recently, the emergence of low ...

Tzeng TT, et al. The stability and immunogenicity of inactivated MDCK cell-derived influenza H7N9 viruses. Vaccine. 2019 Aug 2.  Abstract  
submitted by kickingbird at Aug, 8, 2019 from Vaccine. 2019 Aug 2 (via https://www.sciencedirect.com/science/article/pii/S0264410X1)
In recent years, cell-based influenza vaccines have gained a great interest over the egg-based vaccines. Several inactivated H7N9 vaccines have been evaluated in clinical trials, including whole-virion ...

Liu J, et al. Genetic characterization of influenza A virus and assessment of vaccine efficacy in Yantai from 2014 to 2017. Zhonghua Yu Fang Yi Xue Za Zhi. 2019 Aug 6;53(8):8.  Abstract  
submitted by kickingbird at Aug, 8, 2019 from Zhonghua Yu Fang Yi Xue Za Zhi. 2019 Aug 6;53(8):8 (via https://www.ncbi.nlm.nih.gov/pubmed/31378046)
In this study, the swabs were collected among patients with an influenza-like illness (ILI) admitted to 2 sentinel surveillance hospitals of Yantai from April 2014 to August 2017. All specimen were cultured ...

Wong JY, Goldstein E, Fang VJ, Cowling BJ, Wu P. Real-time estimation of the influenza-associated excess mortality in Hong Kong. Epidemiol Infect. 2019 Jan;147:e217.  Abstract  
submitted by kickingbird at Aug, 2, 2019 from Epidemiol Infect. 2019 Jan;147:e217 (via https://www.cambridge.org/core/journals/epidemiology-and-inf)
Statistical models are commonly employed in the estimation of influenza-associated excess mortality that, due to various reasons, is often underestimated by laboratory-confirmed influenza deaths reported ...

Schar D, et al. New frontiers in applied veterinary point-of-capture diagnostics: Toward early detection and control of zoonotic influenza. Influenza Other Respir Viruses. 2019 Jul 23.  Abstract  
submitted by kickingbird at Jul, 27, 2019 from Influenza Other Respir Viruses. 2019 Jul 23 (via https://onlinelibrary.wiley.com/doi/full/10.1111/irv.12648)
Among the chief limitations in achieving early detection and control of animal-origin influenza of pandemic potential in high-risk livestock populations is the existing lag time between sample collection ...

Xu L, et al. A Higher Rate of Pulmonary Fungal Infection in Chronic Obstructive Pulmonary Disease Patients with Influenza in a Large Tertiary Hospital. Respiration. 2019 Jul 22:1-10.  Abstract  
submitted by kickingbird at Jul, 24, 2019 from Respiration. 2019 Jul 22:1-10 (via https://www.karger.com/Article/Abstract/501410)
BACKGROUND: Influenza is considered a self-limiting disease. However, in patients with chronic obstructive pulmonary disease (COPD), it may result in serious outcomes during the flu season.OBJECTIVES: ...

Sedeyn K, Saelens X. New antibody-based prevention and treatment options for influenza. Antiviral Res. 2019 Jul 16:104562.  Abstract  
submitted by kickingbird at Jul, 21, 2019 from Antiviral Res. 2019 Jul 16:104562 (via https://www.sciencedirect.com/science/article/pii/S016635421)
The antigenic diversity of human influenza viruses represents a challenge to the development of vaccines with durable immune protection. In addition, small molecule anti-influenza viral drugs can bring ...

Shi N, et al. Interventions in live poultry markets for the control of avian influenza: A systematic review and meta-analysis. J Infect Dis. 2019 Jul 17..  Abstract  
submitted by kickingbird at Jul, 21, 2019 from J Infect Dis. 2019 Jul 17. (via https://academic.oup.com/jid/advance-article-abstract/doi/10)
BACKGROUND: This review aimed to provide constructive suggestions for the control and management of avian influenza through quantitative and qualitative evaluation of the impact of different live poultry ...

Chen Y, Zhang Y, Xu Z, Wang X, Lu J, Hu W. Avian Influenza A (H7N9) and related Internet search query data in China. Sci Rep. 2019 Jul 18;9(1):10434.  Abstract  
submitted by kickingbird at Jul, 21, 2019 from Sci Rep. 2019 Jul 18;9(1):10434 (via https://www.nature.com/articles/s41598-019-46898-y)
The use of Internet-based systems for infectious disease surveillance has been increasingly explored in recent years. However, few studies have used Internet search query or social media data to monitor ...

Danier J, et al. Clinical Presentation of Influenza in Children 6 to 35 Months of Age: Findings From a Randomized Clinical Trial of Inactivated Quadrivalent Influenza Vaccine. Pediatr Infect Dis J. 2019 Aug;38(8):866-872.  Abstract  
submitted by kickingbird at Jul, 17, 2019 from Pediatr Infect Dis J. 2019 Aug;38(8):866-872 (via https://insights.ovid.com/crossref?an=00006454-201908000-000)
BACKGROUND: In an exploratory analysis of an inactivated quadrivalent influenza vaccine (IIV4) trial in children 6-35 months without risk factors for influenza, we evaluated clinical presentation of influenza ...

Collins JP, et al. Outcomes of immunocompromised adults hospitalized with laboratory-confirmed influenza in the United States, 2011~2015. Clin Infect Dis. 2019 Jul 11..  Abstract  
submitted by kickingbird at Jul, 15, 2019 from Clin Infect Dis. 2019 Jul 11. (via https://academic.oup.com/cid/advance-article-abstract/doi/10)
BACKGROUND: Hospitalized immunocompromised (IC) adults with influenza may have worse outcomes than hospitalized non-immunocompromised adults.METHODS: We identified adults (≥18 years) hospitalized with ...

Carlock MA, et al. Impact of age and pre-existing influenza on the induction of human antibody responses against influenza B viruses. Hum Vaccin Immunother. 2019 Jul 10..  Abstract  
submitted by kickingbird at Jul, 12, 2019 from Hum Vaccin Immunother. 2019 Jul 10. (via https://www.tandfonline.com/doi/abs/10.1080/21645515.2019.16)
Pre-existing immunity to influenza is dependent on a number of factors and can vary greatly within and across influenza subtypes. In this study, volunteers (aged 18-85 years) were vaccinated with split, ...

Chua H, et al. Effectiveness of partial and full influenza vaccination in children aged <9 years in Hong Kong, 2011~2019. J Infect Dis. 2019 Jul 9..  Abstract  
submitted by kickingbird at Jul, 12, 2019 from J Infect Dis. 2019 Jul 9. (via https://academic.oup.com/jid/advance-article-abstract/doi/10)
INTRODUCTION: Two doses of influenza vaccination are recommended for previously unvaccinated children aged METHODS: Using the test-negative design we enrolled 23,187 children aged RESULTS: Overall VE estimates ...

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