WHO launches new global influenza strategy    
submitted by kickingbird at Mar, 12, 2019 from WHO
WHO released a Global Influenza Strategy for 2019-2030 aimed at protecting people in all countries from the threat of influenza. The goal of the strategy is to prevent seasonal influenza, control the spread ...

USCDC: Avian Influenza A(H5N1) U.S. Situation Update and CDC Activities    
submitted by kickingbird at 10 hours ago from USCDC
April 26, 2024 – CDC continues to respond to the public health challenge posed by a multistate outbreak of avian influenza A(H5N1) virus, or “A(H5N1) virus” in dairy cows and other animals in the U.S. ...

USCDC: Urgent field correction notice    
submitted by kickingbird at 21 hours ago from USCDC
The H5b component may fail to amplify, resulting in inconclusive result with CDC's human influenza virus real-time RT-PCR diagnostic panel influenza A/H5 subtyping kit.

Joint FAO/WHO/WOAH preliminary assessment of recent influenza A(H5N1) viruses    
submitted by kickingbird at 2 days ago from FAO/WHO/WOAH
During 2020, highly pathogenic avian influenza (HPAI) A(H5N1) clade 2.3.4.4b viruses arose from previously circulating influenza A(H5Nx) viruses and spread predominantly via migratory birds to many parts ...

Primers and probes for H5 and N1 qRT-PCR detection [CNIC]    
submitted by kickingbird at 2 days ago from National Technical Guidelines(2017 Edition)
CNICH5-Forward 5’-TGG AAA GYG TRA GAA AYG GRA CRT-3’CNICH5-Reverse 5’-YRC TAR GGA ACY CGC CAC TG-3’CNICH5-probe 5’-TAY CCB CAS TAT TCA GAR GAA GC-3’AN1 Forward 5’-TAY AAC TCA AGG TTT GAG TCT GTY GCT ...

Se-Hee An, Na-Yeong Kim, etc.,al. Development and evaluation of a multiplex real-time RT-PCR assay for simultaneous detection of H5, H7, and H9 subtype avian influenza viruses. Journal of Virological Methods.  Abstract  
submitted by kickingbird at 10 hours ago from Journal of Virological Methods
H5, H7 and H9 are the major subtypes of avian influenza virus (AIV) that cause economic losses in the poultry industry and sporadic zoonotic infection. Early detection of AIV is essential for preventing ...

Siru Lin, Junhong Chen, etc.,al. Evolutionary dynamics and comparative pathogenicity of clade 2.3.4.4b H5 subtype avian influenza viruses, China, 2021~2022. Virologica Sinica.  Abstract  
submitted by kickingbird at 10 hours ago from Virologica Sinica
The recent concurrent emergence of H5N1, H5N6, and H5N8 avian influenza viruses (AIVs) has caused significant avian mortality globally. Since 2020, frequent human-animal interactions have been documented. ...

Zhi, Y.; Zhao, X.; Liu, Z.; Shen, G.; Zhang, T.; Z. Oxymatrine Modulation of TLR3 Signaling: A Dual-Action Mechanism for H9N2 Avian Influenza Virus Defense and Immune Regulation. Molecules 2024, 29, 1945.  Abstract  
submitted by kickingbird at 21 hours ago from Molecules 2024, 29, 1945
In our research, we explored a natural substance called Oxymatrine, found in a traditional Chinese medicinal plant, to fight against a common bird flu virus known as H9N2. This virus not only affects birds ...

Sanchez, P.L.; Andre, G.; Antipov, A.; Petrovsky,. Advax-SM?-Adjuvanted COBRA (H1/H3) Hemagglutinin Influenza Vaccines. Vaccines 2024, 12, 455.  Abstract  
submitted by kickingbird at 21 hours ago from Vaccines 2024, 12, 455
Adjuvants enhance immune responses stimulated by vaccines. To date, many seasonal influenza vaccines are not formulated with an adjuvant. In the present study, the adjuvant Advax-SM? was combined with ...

Xia, C.; Wang, T.; Hahm, B. Triggering Degradation of Host Cellular Proteins for Robust Propagation of Influenza Viruses. Int. J. Mol. Sci. 2024, 25, 4677.  Abstract  
submitted by kickingbird at 21 hours ago from Int. J. Mol. Sci. 2024, 25, 4677
Following infection, influenza viruses strive to establish a new host cellular environment optimized for efficient viral replication and propagation. Influenza viruses use or hijack numerous host factors ...