Lindsey R Robinson-McCarthy, etc.,al. [preprint]Dairy cattle herds mount a characteristic antibody response to highly pathogenic H5N1 avian influenza viruses. https://doi.org/10.1101/2025.04.01.646587. Abstract
submitted by kickingbird at 1 days ago from https://doi.org/10.1101/2025.04.01.646587 (via https://www.biorxiv.org/content/10.1101/2025.04.01.646587v1)
An unprecedented outbreak of a highly pathogenic avian influenza virus, H5 clade 2.3.4.4b, was reported in United States dairy cattle during the spring of 2024. It has now spread to hundreds of herds across ... Liu, Y., Deng, S., Ren, S. et al. Intranasal influenza virus-vectored vaccine offers protection against clade 2.3.4.4b H5N1 infection in small animal models. Nat Commun 16, 3133 (2025). Abstract
submitted by kickingbird at 2 days ago from Nat Commun 16, 3133 (2025) (via https://link.springer.com/article/10.1038/s41467-025-58504-z)
The highly pathogenic avian influenza (HPAI) H5N1 virus has been endemic in aquatic birds since 1997, causing outbreaks in domestic poultry and occasional human infections worldwide. Recently, the cross-species ... zhu-nan Li, etc.,al. [preprint]Population Immunity to Hemagglutinin Head, Stalk and Neuraminidase of Highly Pathogenic Avian Influenza 2.3.4.4b A(H5N1) viruses in the United States and the Impact of Seasonal Influenza on. https://doi.org/10.1101/2025.03.30.25323419. Abstract
submitted by kickingbird at 3 days ago from https://doi.org/10.1101/2025.03.30.25323419 (via https://www.medrxiv.org/content/10.1101/2025.03.30.25323419v)
The unprecedented 2.3.4.4b A(H5N1) outbreak in dairy cattle, poultry, and spillover to humans in the United States (US) poses a major public health threat. Population immunity is a critical component of ... Ramya S Barre, etc.,al. [preprint]A Human H5N1 Influenza Virus Expressing Bioluminescence for Evaluating Viral Infection and Identifying Therapeutic Interventions. https://doi.org/10.1101/2025.03.28.646035. Abstract
submitted by kickingbird at 4 days ago from https://doi.org/10.1101/2025.03.28.646035 (via https://www.biorxiv.org/content/10.1101/2025.03.28.646035v1)
A multistate outbreak of highly pathogenic avian influenza virus (HPAIV) H5N1 in dairy cows was first reported on March 25, 2024, in the United States (US), marking the first discovery of HPAIV H5N1 in ... Ahmed Mostafa, etc.,al. [preprint]A Live Attenuated Vaccine Candidate against Emerging Highly Pathogenic Cattle-Origin 2.3.4.4b H5N1 Viruses. https://doi.org/10.1101/2025.03.28.646033. Abstract
submitted by kickingbird at 4 days ago from https://doi.org/10.1101/2025.03.28.646033 (via https://www.biorxiv.org/content/10.1101/2025.03.28.646033v1)
Influenza viruses present a significant public health risk, causing substantial illness and death in humans each year. Seasonal flu vaccines must be updated regularly, and their effectiveness often decreases ... Jia Li, Tangqi Wang, Xiaojuan Guo, Yujie Jiang,etc. Broad Mucosal and Systemic Immunity in Mice Induced by Intranasal Booster With a Novel Recombinant Adenoviral Based Vaccine Protects Against Divergent Influenza A Virus. Journal of Medical Virology. Abstract
submitted by kickingbird at 4 days ago from Journal of Medical Virology (via https://onlinelibrary.wiley.com/doi/10.1002/jmv.70326)
The development of broad-spectrum universal influenza vaccines and optimization of vaccination strategies to address the threats posed by pandemics and emerging influenza viruses are critical for public ... Phrutsamon Wongnak, etc.,al. [preprint]Characterising viral clearance kinetics in acute influenza. https://doi.org/10.1101/2025.03.07.25323547. Abstract
submitted by kickingbird at 4 days ago from https://doi.org/10.1101/2025.03.07.25323547 (via https://www.medrxiv.org/content/10.1101/2025.03.07.25323547v)
Pharmacometric assessment of antiviral efficacy in acute influenza informs treatment decisions and pandemic preparedness. We assessed natural viral clearance in untreated acute influenza to guide clinical ... Poulami Basu Thakur, etc.,al. [preprint]Heterogeneity across mammalian- and avian-origin A(H1N1) influenza viruses influences viral infectivity following incubation with host bacteria from the human respiratory tract. https://doi.org/10.1101/2025.03.28.645935. Abstract
submitted by kickingbird at 4 days ago from https://doi.org/10.1101/2025.03.28.645935 (via https://www.biorxiv.org/content/10.1101/2025.03.28.645935v1)
Influenza A viruses (IAV) are primarily transmitted between mammals by the respiratory route, and encounter bacteria in the respiratory tract before infecting susceptible epithelial cells. Previous studies ... Li L, Chen R, Yan Z, Cai Q, Guan Y, Zhu H. Experimental Infection of Rats with Influenza A Viruses: Implications for Murine Rodents in Influenza A Virus Ecology. Viruses. 2025; 17(4):495. Abstract
submitted by kickingbird at 4 days ago from Viruses. 2025; 17(4):495 (via https://www.mdpi.com/1999-4915/17/4/495)
Rattus norvegicus (brown rat), a widely distributed rodent and common biomedical model, is a known reservoir for many zoonotic pathogens but has not been traditionally recognized as a host for influenza ... Guangxu Zhang, Yuren Shi, Haoyu Ge, Yuanzhou Wang,. Genomic signatures and host adaptation of H5N1 clade 2.3.4.4b: A call for global surveillance and multi-target antiviral strategies. Current Research in Microbial Sciences. Abstract
submitted by kickingbird at 4 days ago from Current Research in Microbial Sciences (via https://www.sciencedirect.com/science/article/pii/S266651742)
The recent report of the first fatality associated with infection by influenza virus H5N1 clade 2.3.4.4b, identified as genotype D1.1, which is distinct from the B3.13 genotype, has sparked fears of a ... Frutos AM, Tenforde MW, Sundaresan D, Naleway AL,. Influenza-associated hospitalization rates by underlying conditions, 2016-17 to 2019-20: A retrospective cohort study. J Infect Dis. 2025 Mar 28:jiaf164. Abstract
submitted by kickingbird at 5 days ago from J Infect Dis. 2025 Mar 28:jiaf164 (via https://pubmed.ncbi.nlm.nih.gov/40155312/)
Background: Various underlying medical conditions (UMCs) elevate the risk of influenza-associated hospitalization. We evaluated how these rates changed by type and number of UMCs.Methods: Retrospective ... Ishiguro N, Morioka I, Nakano T, Manabe A, Kawaguc. Clinical and Virologic Outcomes of Baloxavir Compared with Oseltamivir in Pediatric Patients with Influenza in Japan. Infect Dis Ther. 2025 Mar 28. Abstract
submitted by kickingbird at 5 days ago from Infect Dis Ther. 2025 Mar 28 (via https://pubmed.ncbi.nlm.nih.gov/40155497/)
Introduction: Baloxavir marboxil, a cap-dependent endonuclease inhibitor, has proven efficacy against influenza. There are limited comparative data between baloxavir and oseltamivir in Japanese pediatric ... Aaron M Frutos, Mark W Tenforde, Devi Sundaresan,. Influenza-associated hospitalization rates by underlying conditions, 2016~17 to 2019~20: A retrospective cohort study. The Journal of Infectious Diseases, 2025;, jiaf164. Abstract
submitted by kickingbird at 6 days ago from The Journal of Infectious Diseases, 2025;, jiaf164 (via https://academic.oup.com/jid/advance-article-abstract/doi/10)
BackgroundVarious underlying medical conditions (UMCs) elevate the risk of influenza-associated hospitalization. We evaluated how these rates changed by type and number of UMCs.MethodsRetrospective cohorts ... Yu L, Jiang Y, Rang H, Wang X, Cai Y, Yan H, Wu S,. Restriction of influenza A virus replication by host DCAF7-CRL4B axis. J Virol. 2025 Mar 27:e0013325. Abstract
submitted by kickingbird at 6 days ago from J Virol. 2025 Mar 27:e0013325 (via https://journals.asm.org/doi/10.1128/jvi.00133-25)
The balance between cellular defense and viral escape determines the fate of influenza A virus (IAV) infection. Viral polymerase activity is critical for the replication and propagation of IAV. The antiviral ... Cordero-Ortiz M, Magtoto R, Cauwels B, Baum DH, Ar. Fluorescent Microsphere Immunoassay for Isotype-Specific H5N1 Antibody Detection in Serum and Milk Samples From Dairy Cattle: A Tool for Epidemiological Surveillance. J Med Virol. 2025 Apr;97(4):e70321. Abstract
submitted by kickingbird at 6 days ago from J Med Virol. 2025 Apr;97(4):e70321 (via https://pubmed.ncbi.nlm.nih.gov/40145266/)
The detection of highly pathogenic avian influenza A virus H5N1 in dairy cows in the United States underscores the urgent need for reliable laboratory tools to support epidemiological surveillance. This ... Bessière Pierre, Brun Jessie, Hayes Brandon, March. Cats as sentinels of mammal exposure to H5Nx avian influenza viruses: a seroprevalence study, France, December 2023 to January 2025. Euro Surveill. 2025;30(12):pii=2500189. Abstract
submitted by kickingbird at 7 days ago from Euro Surveill. 2025;30(12):pii=2500189 (via https://www.eurosurveillance.org/content/10.2807/1560-7917.E)
Highly pathogenicity avian influenza viruses (HPAIV) H5Nx of clade 2.3.4.4b have circulated extensively in recent years and become enzootic in many regions since 2020. This increased circulation has led ... Wang, Yan-He et al. Early-warning signals and the role of H9N2 in the spillover of avian influenza viruses. Med, Mar 25, 2025. Abstract
submitted by kickingbird at 7 days ago from Med, Mar 25, 2025 (via https://www.cell.com/med/fulltext/S2666-6340(25)00066-2)
BackgroundThe spillover of avian influenza viruses (AIVs) presents a significant global public health threat, leading to unpredictable and recurring pandemics. Current pandemic assessment tools suffer ... Stachler E, Gnirke A, McMahon K, et al. Establishing Methods to Monitor Influenza (A)H5N1 Virus in Dairy Cattle Milk, Massachusetts, USA. Emerging Infectious Diseases. 2025;31(13). Abstract
submitted by kickingbird at 8 days ago from Emerging Infectious Diseases. 2025;31(13) (via https://wwwnc.cdc.gov/eid/article/31/13/25-0087_article)
Highly pathogenic avian influenza A(H5N1) virus has caused a multistate outbreak among US dairy cattle, spreading across 16 states and infecting hundreds of herds since its onset. We rapidly developed ... Ramey AM, Beckmen KB, Saalfeld DT, Nicholson KL, M. Exposure of Wild Mammals to Influenza A(H5N1) Virus, Alaska, USA, 2020-2023. Emerg Infect Dis. 2025 Apr;31(4):804-808. Abstract
submitted by kickingbird at 8 days ago from Emerg Infect Dis. 2025 Apr;31(4):804-808 (via https://wwwnc.cdc.gov/eid/article/31/4/24-1002_article)
Serum samples from wild mammals inhabiting Alaska, USA, showed that 4 species, including Ursus arctos bears and Vulpes vulpes foxes, were exposed to influenza A(H5N1) viruses. Results indicated some mammals ... Lang Y, Shi L, Roy S, Gupta D, Dai C, Khalid MA, Z. Detection of antibodies against influenza A viruses in cattle. J Virol 0:e02138-24. Abstract
submitted by kickingbird at 8 days ago from J Virol 0:e02138-24 (via https://journals.asm.org/doi/10.1128/jvi.02138-24)
Unexpected outbreaks caused by the H5N1 highly pathogenic avian influenza virus (HPAIV) in dairy cows in the United States (US) have raised significant veterinary and public health concerns. When and how ... 5859 items, 20/Page, Page[1/293][|<<] [|<] [1] [2] [3] [4] [5] [6] [7] [8] [9] [10] [>|] [>>|] |
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