ZHANG Qiang-Zhe, etc.,al. Efficient Protection of H5N1 Influenza Virus DNA Vaccine Delivering by Electroporation in Mammalian and Avian System. Prog．Biochem．Biophy 2005,32(8)
To investigate the protection effect of DNA vaccine in mammalian and avian systems.the DNA vaccine was inoculated in bom BALB/c mice and SPF chickens immunized wim DNA vaccines encoding hemagglutinin (HA)from A/Goose/GuangDong/1/96(H5N1)virus. The mice and chickens were immunized twice,3 weeks apart,by electroporation into muscles or intramuscular injection.
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