To investigate the protection effect of DNA vaccine in mammalian and avian systems.the DNA vaccine was inoculated in bom BALB/c mice and SPF chickens immunized wim DNA vaccines encoding hemagglutinin (HA)from A/Goose/GuangDong/1/96(H5N1)virus. The mice and chickens were immunized twice,3 weeks apart,by electroporation into muscles or intramuscular injection.
H5N1DNAvaccineELectroporation.pdf