VAN DER VRIES E, Ip DK, Cowling BJ, Zhang JD, et a. Outcomes and Susceptibility to Neuraminidase Inhibitors in Individuals Infected with Different Influenza B Lineages: the Influenza Resistance Information Study. J Infect Dis. 2015 Jul 9. pii: jiv375
BACKGROUND:
METHODS:
?Data from patients with influenza B infections from the first 5 years (2009-13) of the prospective Influenza Resistance Information Study (IRIS, NCT00884117) were evaluated. Cultured viruses were phenotypically tested for neuraminidase inhibitor (NAI) sensitivity, and sequenced to determine virus lineage (B/Victoria or B/Yamagata). Differences in clinical outcomes (viral clearance and symptom resolution) between virus lineages were assessed using Kaplan-Meier analysis.
RESULTS:
CONCLUSIONS:
See Also:
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