Washio M, Oura A, Mori M.. Ecological studies on influenza infection and the effect of vaccination: Their advantages and limitations. Vaccine. 2008 Jun 20
Ecological studies lack the ability to control for the effects of confounding factors. The findings of a linear relationship between average exposure and disease frequency in ecological studies do not imply that such a linear relationship will be present at the individual levels. This is known as the ´ecological fallacy´. Despite these limitations, ecological studies may be the best approach to studying exposures that are easier to measure at the group rather than the individual level because most ecological studies make use of routinely collected data. They are also useful for monitoring the effectiveness of population interventions such as vaccination programs, health education campaigns and mass screening programs. Thus, ecological studies are useful epidemiologic tools for public health surveillance if we know their limitations and interpret their results carefully. Ecological studies often help to generate hypotheses, although they rarely provide a strong test of a causal hypothesis.
See Also:
Latest articles in those days:
- Airway organoids reveal patterns of influenza A tropism and adaptation in wildlife species 3 hours ago
- Early nasal and lung transcriptomic profiles reveal pathways associated with divergent clinical outcomes following H7N1 high pathogenicity avian influenza virus infection 3 hours ago
- [preprint]Acquisition of specific human respiratory tract binding of 2.3.4.4b H5N1 hemagglutinins requires multiple mutations 3 hours ago
- [preprint]Infection of the bovine mammary gland by avian H5N1 subclade 2.3.4.4b influenza viruses 3 hours ago
- Imported case of avian influenza A(H9N2) virus infection in a patient with miliary tuberculosis, Italy, March 2026 2 days ago
[Go Top] [Close Window]


