CHEN Yi-feng; JIN Ning-yi; JIA Lei-li;etc.,al. Construction of multiple-epitope rFPV against H3,H5,H7,H9 Subtype influenza A Virus. Immunological Journal
Objective To construct recombinant fowlpox virus (rFPV) co-expressing multi-epitopes of influenza/A subtype H3, H5, H5, H7, and H9 virus. Methods The epitope gene of dominant antigen (HA NA NP M) d of influenza A viruses was selected. The multi-epitopes gene was synthesized and optimized by bioinformatics methods, and then inserted into the H5 H7 HA gene to construct an ORF, which should be cloned into downstream of the complex prompter (ATI-P7.5×20) of pUTA-2 vector to construct the recombinant fowlpox virus...
Fulltext in Chinese can be downloaded at Chinese version of F.I.C
See Also:
Latest articles in those days:
- Structures of H5N1 influenza polymerase with ANP32B reveal mechanisms of genome replication and host adaptation 21 hours ago
- Risk assessment of a highly pathogenic H5N1 influenza virus from mink 21 hours ago
- Detection of clade 2.3.4.4b highly pathogenic H5N1 influenza virus in New York City 21 hours ago
- Sequence-based epitope mapping of high pathogenicity avian influenza H5 clade 2.3.4.4b in Latin America 2 days ago
- Guanylate-binding protein 1 inhibits inflammatory factors produced by H5N1 virus through Its GTPase activity 2 days ago
[Go Top] [Close Window]