WANG Qu-zhi; LONG Jin-xue; HU Shun-lin; WU Yan-tao. Biological significance of amino acids deletion in NA stalk of H5N1 avain influenza virus. Acta Microbiologica Sinica
It has been reported that NA gene of some H1N1 Influenza A virus strains isolated since 1933 is characterized by a deletion of 11 to 16 amino acids in the stalk.The spontaneous mutant in NA stalk of H1N1 virus lacks enzyme activity with large substrate(fetuin) but not with small substrate(sialyllactose).Recently,H5N1 virus also has been found that NA has the same unique mutation in the stalk,a deletion of 15 to 20 amino acids.However,biological significance of this mutation has not yet been reported.In order...
fulltext can be downloaded in Chinese version of FIC
See Also:
Latest articles in those days:
- The evolution, complexity, and diversity of swine influenza viruses in China: A hidden public health threat 19 hours ago
- MHC class II proteins mediate sialic acid independent entry of human and avian H2N2 influenza A viruses 19 hours ago
- Histopathologic Features and Viral Antigen Distribution of H5N1 Highly Pathogenic Avian Influenza Virus Clade 2.3.4.4b from the 2022–2023 Outbreak in Iowa Wild Birds 19 hours ago
- Detection and characterization of H5N1 HPAIV in environmental samples from a dairy farm 23 hours ago
- Genomic Characterization of Highly Pathogenic Avian Influenza A H5N1 Virus Newly Emerged in Dairy Cattle 23 hours ago
[Go Top] [Close Window]