John C. Obenauer, etc.,al. Large-Scale Sequence Analysis of Avian Influenza Isolates. Science DOI: 10.1126/science.1121586
The spread of H5N1 avian influenza viruses (AIV) from China to Europe has raised significant global concern about their potential to infect humans and cause a pandemic. In spite of their significant threat to human health, remarkably little AIV whole genome information is available. We report here a preliminary analysis of the first large-scale sequencing of AIV including 2,196 AIV genes and 169 complete genomes. We combine this new information with public AIV data to identify new gene alleles, persistent genotypes, compensatory mutations, and a potential virulence determinant.
See Also:
Latest articles in those days:
- Nucleic acid detection and genomic sequence analysis of one H5N1 avian influenza virus from wide birds around Qinghai Lake 10 hours ago
- An aggregated dataset of serial morbidity and titer measurements from influenza A virus-infected ferrets 14 hours ago
- Structures of H5N1 influenza polymerase with ANP32B reveal mechanisms of genome replication and host adaptation 3 days ago
- Risk assessment of a highly pathogenic H5N1 influenza virus from mink 3 days ago
- Detection of clade 2.3.4.4b highly pathogenic H5N1 influenza virus in New York City 3 days ago
[Go Top] [Close Window]