Kaye D, Pringle CR. Avian influenza viruses and their implication for human health. Clin Infect Dis. 2005 Jan 1;40(1):108-12. Epub 2004 Dec 07
Widespread outbreaks of avian influenza in domestic fowl throughout eastern Asia have reawakened concern that avian influenza viruses may again cross species barriers to infect the human population and thereby initiate a new influenza pandemic. Simultaneous infection of humans (or swine) by avian influenza viruses in the presence of human influenza viruses could theoretically generate novel influenza viruses with pandemic potential as a result of reassortment of genome subunits between avian and mammalian influenza viruses. These hybrid viruses would have the potential to express surface antigens from avian viruses to which the human population has no preexisting immunity. This article reviews current knowledge of the routes of transmission of avian influenza A viruses to humans, places the risk of appearance of a new pandemic influenza virus in perspective, and describes the recently observed epidemiology and clinical syndromes of avian influenza in humans.
See Also:
Latest articles in those days:
- Nucleic acid detection and genomic sequence analysis of one H5N1 avian influenza virus from wide birds around Qinghai Lake 19 hours ago
- An aggregated dataset of serial morbidity and titer measurements from influenza A virus-infected ferrets 23 hours ago
- Structures of H5N1 influenza polymerase with ANP32B reveal mechanisms of genome replication and host adaptation 4 days ago
- Risk assessment of a highly pathogenic H5N1 influenza virus from mink 4 days ago
- Detection of clade 2.3.4.4b highly pathogenic H5N1 influenza virus in New York City 4 days ago
[Go Top] [Close Window]