Highly pathogenic avian influenza of subtype H5N1 (HPAIV H5N1) reached Antarctica in late 2023/2024 breeding season, but the host ecology and movement processes shaping its incursion and spread remain poorly resolved. We investigated these mechanisms by integrating viral genomics, multi-season serology, and seabird movement data at King George Island (Fildes Peninsula, South Shetland Islands), a likely gateway between South America and the Antarctic Peninsula. Across three breeding seasons (2022/23–2024/25), we collected swabs and blood serum from key scavenging and predatory seabirds (Brown skua, South Polar skua, Southern Giant petrel) and paired these data with light-level geolocator tracks (10–16 full annual tracks per species) and breeding-season GPS tracks (10–20 individuals per species). Phylogenetic analyses including three newly generated HPAIV H5N1 genomes from infected Brown skuas placed these viruses within the South Georgia–Antarctic lineage, consistent with introduction via South Georgia followed by onward spread within the region. Longitudinal serology revealed a rapid increase in cumulative exposure in scavenging species, with antibodies against influenza A virus’ nucleoprotein and hemagglutinin subtype H5 rising to high levels by 2024/25 in Brown skuas (52.2%) and Southern Giant petrels (62.5%), but remaining markedly lower in South Polar skuas (12.5%), consistent with their more pelagic and less scavenging foraging behaviour. Tracking showed that migratory connectivity was greatest during the non-breeding period but contracted rapidly during colony return and early breeding. In contrast, network simulations parameterized by high-percentile breeding-season foraging distances indicated strong peninsula-wide connectivity and non-zero potential links toward South Georgia and other sub-Antarctic stepping-stones. Together, these results provide a mechanistic, host-based framework suggesting that HPAIV H5N1 likely reached Antarctica through the South Georgia pathway, but that its regional spread was shaped primarily by foraging ecology and breeding-season movement networks rather than by long-distance migration.