Many U.S. households keep backyard bird flocks for their personal food supply or as garden partners. Backyard flocks in the United States have occasionally been infected with avian influenza A viruses, putting flock owners at risk for exposure. During July–December 2025, CDC, in collaboration with state health and agricultural partners, conducted an online survey to learn more about backyard flock owners and their knowledge, attitudes, and practices related to avian influenza. Among 638 respondents who completed the survey, 92% were White (and not Hispanic or Latino), and approximately one half had a graduate or professional degree; a majority kept small, predominantly chicken flocks; and many reported that wild birds could access their flock or the flock’s food or water, which increases the flock’s risk for avian influenza exposure. Although a majority of respondents had heard of avian influenza, approximately one third were unaware of the signs and symptoms of infection in their birds or humans. If they needed to interact with ill or dead birds, a majority of owners knew the recommended precautions to take and indicated willingness to use most, though not all, recommended personal protective equipment. These findings highlight important topics for risk messaging and educational resources so that backyard flock owners are better informed and better able to protect their flocks, themselves, and their families from avian influenza.