Luvira V, Thippornchai N, Leaungwutiwong P, Siripo. Evidence of transmission of influenza A and influenza B co-infection in healthcare workers. J Infect Dev Ctries. 2022 Jul 28;16(7):1199-1205
Methodology: We investigated the outbreak setting through the utilization of structural questionnaires, molecular methods, and serological tests.
Results: Among 13 persons, one index case and five confirmed secondary cases were confirmed. The overall influenza infection rate was 46.2% (6/13), with infection rates for influenza A and B at 38.5% (5/13) and 23.1% (3/13), respectively. Interestingly, one of the secondary cases had influenza A and B co-infection identical to the index case. There was no significant association between vaccination status and influenza infection.
Conclusions: This study unveils the demonstration of human-to-human influenza A and B co-infection transmission for the first time. Surveillance systems, combined with epidemiological case investigation comprising molecular diagnosis, should be strengthened for future influenza outbreak preparedness.
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